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Volumn 29, Issue 2, 2016, Pages 275-287

Glycyrrhizic acid Attenuates Neuroinflammation and Oxidative Stress in Rotenone Model of Parkinson’s Disease

Author keywords

Glycyrrhizic acid; Inflammation; Neurodegeneration; Oxidative stress; Parkinson s disease; Rotenone

Indexed keywords

CATALASE; CYCLOOXYGENASE 2; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLYCYRRHIZIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1; MALONALDEHYDE; MEMBRANE PROTEIN; ROTENONE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, RAT; AUTACOID; CALCIUM BINDING PROTEIN; NOS2 PROTEIN, RAT; PTGS2 PROTEIN, RAT;

EID: 84954360343     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-015-9579-z     Document Type: Article
Times cited : (70)

References (37)
  • 1
    • 84893071526 scopus 로고    scopus 로고
    • Pathogenesis-targeted disease-modifying therapies in Parkinson disease
    • COI: 1:CAS:528:DC%2BC2cXhsFCitb0%3D
    • Al Dakheel A, Kalia LV, Lang AE (2014) Pathogenesis-targeted disease-modifying therapies in Parkinson disease. Neurotherapeutics 11:6–23
    • (2014) Neurotherapeutics , vol.11 , pp. 6-23
    • Al Dakheel, A.1    Kalia, L.V.2    Lang, A.E.3
  • 3
    • 84896401100 scopus 로고    scopus 로고
    • Neurodegeneration in Parkinson’s disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins
    • PID: 24085563, COI: 1:CAS:528:DC%2BC3sXhsFKiur%2FJ
    • Anderson G, Maes M (2014) Neurodegeneration in Parkinson’s disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins. Mol Neurobiol 49:771–783
    • (2014) Mol Neurobiol , vol.49 , pp. 771-783
    • Anderson, G.1    Maes, M.2
  • 4
    • 46849110600 scopus 로고    scopus 로고
    • Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds
    • PID: 18446848, COI: 1:CAS:528:DC%2BD1cXpsVCqu7s%3D
    • Asl MN, Hosseinzadeh H (2008) Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res 22:709–724
    • (2008) Phytother Res , vol.22 , pp. 709-724
    • Asl, M.N.1    Hosseinzadeh, H.2
  • 5
    • 0033681149 scopus 로고    scopus 로고
    • Chronic systemic pesticide exposure reproduces features of Parkinson’s disease
    • PID: 11100151, COI: 1:CAS:528:DC%2BD3cXosVGgsbg%3D
    • Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT (2000) Chronic systemic pesticide exposure reproduces features of Parkinson’s disease. Nat Neurosci 3:1301–1306
    • (2000) Nat Neurosci , vol.3 , pp. 1301-1306
    • Betarbet, R.1    Sherer, T.B.2    MacKenzie, G.3    Garcia-Osuna, M.4    Panov, A.V.5    Greenamyre, J.T.6
  • 6
  • 7
    • 84896727104 scopus 로고    scopus 로고
    • Unravelling mitochondrial pathways to Parkinson's disease
    • PID: 24117181, COI: 1:CAS:528:DC%2BC2cXltFejsrw%3D
    • Celardo I, Martins LM, Gandhi S (2014) Unravelling mitochondrial pathways to Parkinson's disease. Br J Pharmacol 171(8):1943–1957
    • (2014) Br J Pharmacol , vol.171 , Issue.8 , pp. 1943-1957
    • Celardo, I.1    Martins, L.M.2    Gandhi, S.3
  • 8
    • 0027434596 scopus 로고
    • Glutathione peroxidase, glial cells and Parkinson’s disease
    • PID: 8433802, COI: 1:STN:280:DyaK3s7msFWktg%3D%3D
    • Damier P, Hirsch EC, Zhang P, Agid Y, Javoy-Agid F (1993) Glutathione peroxidase, glial cells and Parkinson’s disease. Neuroscience 52:1–6
    • (1993) Neuroscience , vol.52 , pp. 1-6
    • Damier, P.1    Hirsch, E.C.2    Zhang, P.3    Agid, Y.4    Javoy-Agid, F.5
  • 9
    • 84881427177 scopus 로고    scopus 로고
    • Parkinson disease: from pathology to molecular disease mechanisms
    • PID: 23380027, COI: 1:CAS:528:DC%2BC3sXjtlykt7c%3D
    • Dexter DT, Jenner P (2013) Parkinson disease: from pathology to molecular disease mechanisms. Free Radic Biol Med 62:132–144
    • (2013) Free Radic Biol Med , vol.62 , pp. 132-144
    • Dexter, D.T.1    Jenner, P.2
  • 11
    • 18444371726 scopus 로고    scopus 로고
    • Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats
    • PID: 15635186, COI: 1:CAS:528:DC%2BD2MXjsVejtL0%3D
    • Fujikawa T, Kanada N, Shimada A, Ogata M, Suzuki I, Hayashi I, Nakashima K (2005) Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats. Biol Pharm Bull 28:169–172
    • (2005) Biol Pharm Bull , vol.28 , pp. 169-172
    • Fujikawa, T.1    Kanada, N.2    Shimada, A.3    Ogata, M.4    Suzuki, I.5    Hayashi, I.6    Nakashima, K.7
  • 12
    • 84897086481 scopus 로고    scopus 로고
    • Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats
    • PID: 24594628
    • Gong G, Xiang L, Yuan L, Hu L, Wu W, Cai L, Yin L, Dong H (2014) Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats. PLoS ONE 9:e89450
    • (2014) PLoS ONE , vol.9 , pp. e89450
    • Gong, G.1    Xiang, L.2    Yuan, L.3    Hu, L.4    Wu, W.5    Cai, L.6    Yin, L.7    Dong, H.8
  • 13
    • 0033169233 scopus 로고    scopus 로고
    • Interleukin-1β, inducible nitric oxide synthase, and nuclear factor-κB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-γ injection
    • PID: 10412030
    • Hartlage-Rübsamen M, Lemke R, Schliebs R (1999) Interleukin-1β, inducible nitric oxide synthase, and nuclear factor-κB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-γ injection. J Neurosci Res 57:388–398
    • (1999) J Neurosci Res , vol.57 , pp. 388-398
    • Hartlage-Rübsamen, M.1    Lemke, R.2    Schliebs, R.3
  • 14
    • 84920184454 scopus 로고    scopus 로고
    • An update on the rotenone models of Parkinson’s disease: their ability to reproduce the features of clinical disease and model gene-environment interactions
    • Johnson ME, Bobrovskaya L (2014) An update on the rotenone models of Parkinson’s disease: their ability to reproduce the features of clinical disease and model gene-environment interactions. Neurotoxicology 46C:101–116
    • (2014) Neurotoxicology , vol.46C , pp. 101-116
    • Johnson, M.E.1    Bobrovskaya, L.2
  • 15
    • 70649107801 scopus 로고    scopus 로고
    • Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes
    • PID: 19818347, COI: 1:CAS:528:DC%2BD1MXhsV2mtLrK
    • Kawakami Z, Ikarashi Y, Kase Y (2010) Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. Eur J Pharmacol 626:154–158
    • (2010) Eur J Pharmacol , vol.626 , pp. 154-158
    • Kawakami, Z.1    Ikarashi, Y.2    Kase, Y.3
  • 16
    • 84868152531 scopus 로고    scopus 로고
    • Recent updates in redox regulation and free radical scavenging effects by herbal products in experimental models of Parkinson’s disease
    • PID: 23014498, COI: 1:CAS:528:DC%2BC38XhvVyisbnP
    • Koppula S, Kumar H, More SV, Lim HW, Hong SM, Choi DK (2012) Recent updates in redox regulation and free radical scavenging effects by herbal products in experimental models of Parkinson’s disease. Molecules 17:11391–11420
    • (2012) Molecules , vol.17 , pp. 11391-11420
    • Koppula, S.1    Kumar, H.2    More, S.V.3    Lim, H.W.4    Hong, S.M.5    Choi, D.K.6
  • 17
    • 0035665020 scopus 로고    scopus 로고
    • Possible new role for NF-kappaB in the resolution of inflammation
    • PID: 11726968, COI: 1:CAS:528:DC%2BD3MXovFGqurc%3D
    • Lawrence T, Gilroy DW, Colville-Nash PR, Willoughby DA (2001) Possible new role for NF-kappaB in the resolution of inflammation. Nat Med 7:1291–1297
    • (2001) Nat Med , vol.7 , pp. 1291-1297
    • Lawrence, T.1    Gilroy, D.W.2    Colville-Nash, P.R.3    Willoughby, D.A.4
  • 18
    • 79952172294 scopus 로고    scopus 로고
    • Inflammatory mechanisms of neurodegeneration in toxin-based models of Parkinson’s disease
    • Litteljohn D, Mangano E, Clarke M, Bobyn J, Moloney K, Hayley S (2011) Inflammatory mechanisms of neurodegeneration in toxin-based models of Parkinson’s disease. Parkinson’s Dis 2010:713517
    • (2011) Parkinson’s Dis , vol.2010 , pp. 713517
    • Litteljohn, D.1    Mangano, E.2    Clarke, M.3    Bobyn, J.4    Moloney, K.5    Hayley, S.6
  • 19
    • 84929464105 scopus 로고    scopus 로고
    • Glycyrrhizin attenuates kainic Acid-induced neuronal cell death in the mouse hippocampus
    • PID: 23833559
    • Luo L, Jin Y, Kim ID, Lee JK (2013) Glycyrrhizin attenuates kainic Acid-induced neuronal cell death in the mouse hippocampus. Exp Neurobiol 22:107–115
    • (2013) Exp Neurobiol , vol.22 , pp. 107-115
    • Luo, L.1    Jin, Y.2    Kim, I.D.3    Lee, J.K.4
  • 20
    • 84860365643 scopus 로고    scopus 로고
    • Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson’s disease
    • PID: 22417924, COI: 1:CAS:528:DC%2BC38XkvFSrt70%3D
    • Martin HL, Mounsey RB, Mustafa S, Sathe K, Teismann P (2012) Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson’s disease. Exp Neurol 235:528–538
    • (2012) Exp Neurol , vol.235 , pp. 528-538
    • Martin, H.L.1    Mounsey, R.B.2    Mustafa, S.3    Sathe, K.4    Teismann, P.5
  • 21
    • 84878871995 scopus 로고    scopus 로고
    • High throughput screening to identify natural human monoamine oxidase B inhibitors
    • PID: 22887993, COI: 1:CAS:528:DC%2BC3sXpt1ektrY%3D
    • Mazzio E, Deiab S, Park K, Soliman KF (2013) High throughput screening to identify natural human monoamine oxidase B inhibitors. Phytother Res 27:818–828
    • (2013) Phytother Res , vol.27 , pp. 818-828
    • Mazzio, E.1    Deiab, S.2    Park, K.3    Soliman, K.F.4
  • 22
    • 84894384733 scopus 로고    scopus 로고
    • The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson’s disease: focus on astrocytes
    • PID: 23783559, COI: 1:CAS:528:DC%2BC2cXitFyisrk%3D
    • Niranjan R (2014) The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson’s disease: focus on astrocytes. Mol Neurobiol 49:28–38
    • (2014) Mol Neurobiol , vol.49 , pp. 28-38
    • Niranjan, R.1
  • 23
    • 84870246788 scopus 로고    scopus 로고
    • Glycyrrhiza glabra protects from myocardial ischemia-reperfusion injury by improving hemodynamic, biochemical, histopathological and ventricular function
    • PID: 21975080, COI: 1:CAS:528:DC%2BC38XhslKqsbbP
    • Ojha S, Golechha M, Kumari S, Bhatia J, Arya DS (2013) Glycyrrhiza glabra protects from myocardial ischemia-reperfusion injury by improving hemodynamic, biochemical, histopathological and ventricular function. Exp Toxicol Pathol 65:219–227
    • (2013) Exp Toxicol Pathol , vol.65 , pp. 219-227
    • Ojha, S.1    Golechha, M.2    Kumari, S.3    Bhatia, J.4    Arya, D.S.5
  • 24
    • 0025057048 scopus 로고
    • Glutathione peroxidase, superoxide dismutase, and catalase inactivation by peroxides and oxygen derived free radicals
    • PID: 2308398, COI: 1:CAS:528:DyaK3cXhsleksLY%3D
    • Pigeolet E, Corbisier P, Houbion A, Lambert D, Michiels C, Raes M, Zachary MD, Remacle J (1990) Glutathione peroxidase, superoxide dismutase, and catalase inactivation by peroxides and oxygen derived free radicals. Mech Ageing Dev 51:283–297
    • (1990) Mech Ageing Dev , vol.51 , pp. 283-297
    • Pigeolet, E.1    Corbisier, P.2    Houbion, A.3    Lambert, D.4    Michiels, C.5    Raes, M.6    Zachary, M.D.7    Remacle, J.8
  • 25
    • 84906306620 scopus 로고    scopus 로고
    • Slowing of neurodegeneration in Parkinson’s disease and Huntington’s disease: future therapeutic perspectives
    • PID: 24954676, COI: 1:CAS:528:DC%2BC2cXhtVanu7jL
    • Schapira AH, Olanow CW, Greenamyre JT, Bezard E (2014) Slowing of neurodegeneration in Parkinson’s disease and Huntington’s disease: future therapeutic perspectives. Lancet 384:545–555
    • (2014) Lancet , vol.384 , pp. 545-555
    • Schapira, A.H.1    Olanow, C.W.2    Greenamyre, J.T.3    Bezard, E.4
  • 26
    • 0037402801 scopus 로고    scopus 로고
    • Selective microglial activation in the rat rotenone model of Parkinson’s disease
    • PID: 12686372, COI: 1:CAS:528:DC%2BD3sXislensrs%3D
    • Sherer TB, Betarbet R, Kim JH, Greenamyre JT (2003) Selective microglial activation in the rat rotenone model of Parkinson’s disease. Neurosci Lett 341:87–90
    • (2003) Neurosci Lett , vol.341 , pp. 87-90
    • Sherer, T.B.1    Betarbet, R.2    Kim, J.H.3    Greenamyre, J.T.4
  • 28
    • 84856225515 scopus 로고    scopus 로고
    • Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models?
    • PID: 22212501, COI: 1:CAS:528:DC%2BC38Xht1OgtLg%3D
    • Song JX, Sze SC, Ng TB, Lee CK, Leung GP, Shaw PC, Tong Y, Zhang YB (2012) Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models? J Ethnopharmacol 139:698–711
    • (2012) J Ethnopharmacol , vol.139 , pp. 698-711
    • Song, J.X.1    Sze, S.C.2    Ng, T.B.3    Lee, C.K.4    Leung, G.P.5    Shaw, P.C.6    Tong, Y.7    Zhang, Y.B.8
  • 29
    • 84890960121 scopus 로고    scopus 로고
    • Glycyrrhizin alleviates neuroinflammation and memory deficit induced by systemic lipopolysaccharide treatment in mice
    • PID: 24352029
    • Song JH, Lee JW, Shim B, Lee CY, Choi S, Kang C, Sohn NW, Shin JW (2013) Glycyrrhizin alleviates neuroinflammation and memory deficit induced by systemic lipopolysaccharide treatment in mice. Molecules 18:15788–15803
    • (2013) Molecules , vol.18 , pp. 15788-15803
    • Song, J.H.1    Lee, J.W.2    Shim, B.3    Lee, C.Y.4    Choi, S.5    Kang, C.6    Sohn, N.W.7    Shin, J.W.8
  • 30
    • 84898471667 scopus 로고    scopus 로고
    • Vitamin A and carotenoids and the risk of Parkinson’s disease: a systematic review and meta-analysis
    • PID: 24356061
    • Takeda A, Nyssen OP, Syed A, Jansen E, Bueno-de-Mesquita B, Gallo V (2014) Vitamin A and carotenoids and the risk of Parkinson’s disease: a systematic review and meta-analysis. Neuroepidemiology 42:25–38
    • (2014) Neuroepidemiology , vol.42 , pp. 25-38
    • Takeda, A.1    Nyssen, O.P.2    Syed, A.3    Jansen, E.4    Bueno-de-Mesquita, B.5    Gallo, V.6
  • 31
    • 84875703698 scopus 로고    scopus 로고
    • Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson’s disease
    • PID: 23291248, COI: 1:CAS:528:DC%2BC3sXit1yksbs%3D
    • Taylor JM, Main BS, Crack PJ (2013) Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson’s disease. Neurochem Int 62:803–819
    • (2013) Neurochem Int , vol.62 , pp. 803-819
    • Taylor, J.M.1    Main, B.S.2    Crack, P.J.3
  • 32
    • 84905057923 scopus 로고    scopus 로고
    • Involvement of the ERK pathway in the protective effects of glycyrrhizic acid against the MPP + -induced apoptosis of dopaminergic neuronal cells
    • PID: 24993693, COI: 1:CAS:528:DC%2BC2cXhs1yiurzF
    • Teng L, Kou C, Lu C, Xu J, Xie J, Lu J, Liu Y, Wang Z, Wang D (2014) Involvement of the ERK pathway in the protective effects of glycyrrhizic acid against the MPP + -induced apoptosis of dopaminergic neuronal cells. Int J Mol Med 34:742–748
    • (2014) Int J Mol Med , vol.34 , pp. 742-748
    • Teng, L.1    Kou, C.2    Lu, C.3    Xu, J.4    Xie, J.5    Lu, J.6    Liu, Y.7    Wang, Z.8    Wang, D.9
  • 33
    • 67650094606 scopus 로고    scopus 로고
    • Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson’s disease
    • PID: 19375462, COI: 1:CAS:528:DC%2BD1MXoslSju7w%3D
    • Verma R, Nehru B (2009) Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson’s disease. Neurochem Int 55:369–375
    • (2009) Neurochem Int , vol.55 , pp. 369-375
    • Verma, R.1    Nehru, B.2
  • 34
    • 84906505476 scopus 로고    scopus 로고
    • ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells
    • PID: 25075574, COI: 1:CAS:528:DC%2BC2cXitFOit7zN
    • Wang D, Guo TQ, Wang ZY, Lu JH, Liu DP, Meng QF, Xie J, Zhang XL, Liu Y, Teng LS (2014) ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells. Braz J Med Biol Res 47:773–779
    • (2014) Braz J Med Biol Res , vol.47 , pp. 773-779
    • Wang, D.1    Guo, T.Q.2    Wang, Z.Y.3    Lu, J.H.4    Liu, D.P.5    Meng, Q.F.6    Xie, J.7    Zhang, X.L.8    Liu, Y.9    Teng, L.S.10
  • 36
    • 79960434600 scopus 로고    scopus 로고
    • Effects of glycyrrhizic acid on peroxisome proliferator-activated receptor gamma (PPAR-gamma), lipoprotein lipase (LPL), serum lipid and HOMA-IR in rats
    • PID: 20011054
    • Yoke Yin C, So Ha T, Abdul Kadir K (2010) Effects of glycyrrhizic acid on peroxisome proliferator-activated receptor gamma (PPAR-gamma), lipoprotein lipase (LPL), serum lipid and HOMA-IR in rats. PPAR Res 2010:530265
    • (2010) PPAR Res , vol.2010 , pp. 530265
    • Yoke Yin, C.1    So Ha, T.2    Abdul Kadir, K.3
  • 37
    • 84859949806 scopus 로고    scopus 로고
    • Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced neurotoxicity
    • PID: 22540007, COI: 1:CAS:528:DC%2BC38Xms1ClsrY%3D
    • Zhu X, Chen C, Ye D, Guan D, Ye L, Jin J, Zhao H, Chen Y, Wang Z, Wang X, Xu Y (2012) Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced neurotoxicity. PLoS ONE 7:e35823
    • (2012) PLoS ONE , vol.7 , pp. e35823
    • Zhu, X.1    Chen, C.2    Ye, D.3    Guan, D.4    Ye, L.5    Jin, J.6    Zhao, H.7    Chen, Y.8    Wang, Z.9    Wang, X.10    Xu, Y.11


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