ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells

Brazilian Journal of Medical and Biological Research

Volumn 47, Issue 9, 2014, Pages 773-779

  Wang, D ^a   Guo, T Q ^a   Wang, Z Y ^a   Lu, J H ^a   Liu, D P ^a   Meng, Q F ^a   Xie, J ^a   Zhang, X L ^b   Liu, Y ^a   Teng, L S ^a  

^a JILIN UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

ERKs; Glutamate; Glycyrrhizic acid; Mitochondria; Neuroprotection

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL) CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CYTOCHROME C; GLYCYRRHIZIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; UNCLASSIFIED DRUG; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTIINFLAMMATORY AGENT; CHROMONE DERIVATIVE; ENZYME INHIBITOR; FLAVONOID; GLUTAMIC ACID; MORPHOLINE DERIVATIVE; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOIMMUNOPRECIPITATION; RAT; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; WESTERN BLOTTING; ANIMAL; APOPTOSIS; CELL SURVIVAL; CLASSIFICATION; CYTOLOGY; DRUG EFFECTS; ISOLATION AND PURIFICATION; MITOCHONDRION; PC12 CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DIFFERENTIATION; CELL SURVIVAL; CHROMONES; CYTOCHROMES C; ENZYME INHIBITORS; FLAVONOIDS; GLUTAMIC ACID; GLYCYRRHIZIC ACID; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; MORPHOLINES; NEUROPROTECTIVE AGENTS; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SIGNAL TRANSDUCTION;

EID: 84906505476     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/1414-431X20143760     Document Type: Article

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