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Volumn 29, Issue 2, 2016, Pages 325-343

Zinc Modulates Nanosilver-Induced Toxicity in Primary Neuronal Cultures

Author keywords

Cell death; Free radicals; Nanotoxicity; NMDA receptor; TPEN; Zinc homeostasis

Indexed keywords

CHELATING AGENT; DIZOCILPINE; N,N,N,N TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; REACTIVE OXYGEN METABOLITE; SILVER NANOPARTICLE; UNCLASSIFIED DRUG; ZINC; ZINC CHLORIDE; ZINC ION; CALCIUM; ETHYLENEDIAMINE DERIVATIVE; METAL NANOPARTICLE; N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE; SILVER;

EID: 84954339080     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-015-9583-3     Document Type: Article
Times cited : (22)

References (61)
  • 2
    • 0033788519 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release
    • PID: 11032877, COI: 1:CAS:528:DC%2BD3cXns1ejtb8%3D
    • Aizenman E, Stout AK, Hartnett KA, Dineley KE, McLaughlin B, Reynolds IJ (2000) Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. J Neurochem 75:1878–1888
    • (2000) J Neurochem , vol.75 , pp. 1878-1888
    • Aizenman, E.1    Stout, A.K.2    Hartnett, K.A.3    Dineley, K.E.4    McLaughlin, B.5    Reynolds, I.J.6
  • 4
    • 63449105617 scopus 로고    scopus 로고
    • Cytotoxicity and genotoxicity of silver nanoparticles in human cells
    • PID: 19236062, COI: 1:CAS:528:DC%2BD1MXotA%3D%3D
    • AshaRani PV, Mun GLK, Hande MP, Valiyaveettil S (2009) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 3:279–290
    • (2009) ACS Nano , vol.3 , pp. 279-290
    • AshaRani, P.V.1    Mun, G.L.K.2    Hande, M.P.3    Valiyaveettil, S.4
  • 5
    • 0021287299 scopus 로고
    • 2+ from brain tissue during activity
    • PID: 6717566, COI: 1:CAS:528:DyaL2cXhvV2mtbk%3D
    • 2+ from brain tissue during activity. Nature 308:734–736
    • (1984) Nature , vol.308 , pp. 734-736
    • Assaf, S.Y.1    Chung, S.H.2
  • 6
    • 0035696301 scopus 로고    scopus 로고
    • Functions of zinc in signaling, proliferation and differentiation of mammalian cells
    • PID: 11831463, COI: 1:CAS:528:DC%2BD38XpsFWrug%3D%3D
    • Beyersmann D, Haase H (2001) Functions of zinc in signaling, proliferation and differentiation of mammalian cells. Biometals 14:331–341
    • (2001) Biometals , vol.14 , pp. 331-341
    • Beyersmann, D.1    Haase, H.2
  • 7
    • 0025239795 scopus 로고
    • The physiological role of zinc as an antioxidant
    • PID: 2187766, COI: 1:CAS:528:DyaK3MXks1yqtbg%3D
    • Bray TM, Bettge WJ (1990) The physiological role of zinc as an antioxidant. Free Radic Biol Med 8:281–291
    • (1990) Free Radic Biol Med , vol.8 , pp. 281-291
    • Bray, T.M.1    Bettge, W.J.2
  • 9
    • 55949113520 scopus 로고    scopus 로고
    • Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species
    • PID: 18831567, COI: 1:CAS:528:DC%2BD1cXhtF2gs7jP
    • Carlson C, Hussain SM, Schrand AM, Braydich-Stolle LK, Hess KL, Jones RL, Schlager JJ (2008) Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J Phys Chem B 112:13608–13619
    • (2008) J Phys Chem B , vol.112 , pp. 13608-13619
    • Carlson, C.1    Hussain, S.M.2    Schrand, A.M.3    Braydich-Stolle, L.K.4    Hess, K.L.5    Jones, R.L.6    Schlager, J.J.7
  • 11
    • 84875823626 scopus 로고    scopus 로고
    • Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions
    • PID: 23296910, COI: 1:CAS:528:DC%2BC3sXltVantQ%3D%3D
    • Cronholm P, Karlsson HL, Hedberg J, Lowe TA, Winnberg L, Elihn K, Wallinder IO, Möller L (2013) Intracellular uptake and toxicity of Ag and CuO nanoparticles: a comparison between nanoparticles and their corresponding metal ions. Small 9:970–982
    • (2013) Small , vol.9 , pp. 970-982
    • Cronholm, P.1    Karlsson, H.L.2    Hedberg, J.3    Lowe, T.A.4    Winnberg, L.5    Elihn, K.6    Wallinder, I.O.7    Möller, L.8
  • 13
    • 34447513255 scopus 로고    scopus 로고
    • 2+ in models of excitotoxicity
    • PID: 17343910, COI: 1:CAS:528:DC%2BD2sXotVGgt7w%3D
    • 2+ in models of excitotoxicity. Cell Calcium 42:341–342
    • (2007) Cell Calcium , vol.42 , pp. 341-342
    • Dineley, K.E.1
  • 15
    • 0025954937 scopus 로고
    • 2+ and the potentiation by serum albumin
    • PID: 1684730, COI: 1:CAS:528:DyaK3MXmslWmsL4%3D
    • 2+ and the potentiation by serum albumin. Brain Res 560:282–290
    • (1991) Brain Res , vol.560 , pp. 282-290
    • Eimerl, S.1    Schramm, M.2
  • 16
    • 0027337274 scopus 로고
    • 45Ca uptake and acute toxicity mediated by the N-methyl-d-aspartate receptor: the effect of metal binding agents and transition metal ions
    • PID: 8336139, COI: 1:CAS:528:DyaK3sXlvFKgs78%3D
    • 45Ca uptake and acute toxicity mediated by the N-methyl-d-aspartate receptor: the effect of metal binding agents and transition metal ions. J Neurochem 61:518–525
    • (1993) J Neurochem , vol.61 , pp. 518-525
    • Eimerl, S.1    Schramm, M.2
  • 17
    • 0024779411 scopus 로고
    • Neurobiology of zinc and zinc-containing neurons
    • PID: 2689380, COI: 1:CAS:528:DyaK3cXksFKitLs%3D
    • Frederickson CJ (1989) Neurobiology of zinc and zinc-containing neurons. Int Rev Neurobiol 31:145–238
    • (1989) Int Rev Neurobiol , vol.31 , pp. 145-238
    • Frederickson, C.J.1
  • 18
    • 34548226964 scopus 로고    scopus 로고
    • Zinc irreversibly damages major enzymem of energy production and antioxidant defense prior to mitochondria mitochondria permeability transition
    • PID: 17565998, COI: 1:CAS:528:DC%2BD2sXoslOnu7k%3D
    • Gazaryan IG, Krasinskaya IP, Kristal BS, Brown AM (2007) Zinc irreversibly damages major enzymem of energy production and antioxidant defense prior to mitochondria mitochondria permeability transition. J Biol Chem 282:24373–24380
    • (2007) J Biol Chem , vol.282 , pp. 24373-24380
    • Gazaryan, I.G.1    Krasinskaya, I.P.2    Kristal, B.S.3    Brown, A.M.4
  • 19
    • 84859046613 scopus 로고    scopus 로고
    • Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses
    • PID: 22240980, COI: 1:CAS:528:DC%2BC38Xks1Siurk%3D
    • Haase A, Rott S, Mantion A, Graf P, Plendl J, Thünemann AF, Meier WP, Taubert A, Luch A, Reiser G (2012) Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses. Toxicol Sci 126:457–468
    • (2012) Toxicol Sci , vol.126 , pp. 457-468
    • Haase, A.1    Rott, S.2    Mantion, A.3    Graf, P.4    Plendl, J.5    Thünemann, A.F.6    Meier, W.P.7    Taubert, A.8    Luch, A.9    Reiser, G.10
  • 20
    • 84888802356 scopus 로고    scopus 로고
    • Oral toxicity of silver ions, silver nanoparticles and colloidal silver—a review
    • COI: 1:CAS:528:DC%2BC2cXlt1Wktg%3D%3D
    • Hadrup N, Lam HR (2014) Oral toxicity of silver ions, silver nanoparticles and colloidal silver—a review. Reg Toxicol Pharmacol 68:1–7
    • (2014) Reg Toxicol Pharmacol , vol.68 , pp. 1-7
    • Hadrup, N.1    Lam, H.R.2
  • 21
    • 0028170444 scopus 로고
    • Zn2 + : an endogenous modulator of ligand-gated ion channels
    • PID: 7845550, COI: 1:CAS:528:DyaK2cXmsFWqtLc%3D
    • Harrison NL, Gibson SJ (1994) Zn2 +: an endogenous modulator of ligand-gated ion channels. Neuropharmacology 33:935–952
    • (1994) Neuropharmacology , vol.33 , pp. 935-952
    • Harrison, N.L.1    Gibson, S.J.2
  • 23
  • 24
    • 0034306017 scopus 로고    scopus 로고
    • 2+ channels and enhanced by extracellular acidity in mouse cortical neurons
    • PID: 11018104, COI: 1:CAS:528:DC%2BD3cXnslWqtr0%3D
    • 2+ channels and enhanced by extracellular acidity in mouse cortical neurons. J Physiol 528:39–52
    • (2000) J Physiol , vol.528 , pp. 39-52
    • Kerchner, G.A.1    Canzoniero, L.M.2    Yu, S.P.3    Ling, C.4    Choi, D.W.5
  • 25
    • 0034672431 scopus 로고    scopus 로고
    • L-type Ca(2+) channel-mediated Zn(2+) toxicity and modulation by ZnT-1 in PC12 cells
    • PID: 11119691, COI: 1:CAS:528:DC%2BD3cXovFGktLg%3D
    • Kim AH, Sheline CT, Tian M, Higashi T, McMahon RJ, Cousins RJ, Choi DW (2000) L-type Ca(2+) channel-mediated Zn(2+) toxicity and modulation by ZnT-1 in PC12 cells. Brain Res 886:99–107
    • (2000) Brain Res , vol.886 , pp. 99-107
    • Kim, A.H.1    Sheline, C.T.2    Tian, M.3    Higashi, T.4    McMahon, R.J.5    Cousins, R.J.6    Choi, D.W.7
  • 26
    • 77955697820 scopus 로고    scopus 로고
    • Toxicity of silver nanoparticles increases during storage because of slow dissolution under release of silver ions
    • COI: 1:CAS:528:DC%2BC3cXpsV2ltbo%3D
    • Kittler S, Greulich C, Diendorf J, Köller M, Epple M (2010) Toxicity of silver nanoparticles increases during storage because of slow dissolution under release of silver ions. Chem Mater 22:4548–4554
    • (2010) Chem Mater , vol.22 , pp. 4548-4554
    • Kittler, S.1    Greulich, C.2    Diendorf, J.3    Köller, M.4    Epple, M.5
  • 27
    • 0029777299 scopus 로고    scopus 로고
    • The role of zinc in selective neuronal death after transient global cerebral ischemia
    • PID: 8638123, COI: 1:CAS:528:DyaK28XjtVejsrw%3D
    • Koh JY, Suh SW, Gwag BJ, He YY, Hsu CY, Choi DW (1996) The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272:1013–1016
    • (1996) Science , vol.272 , pp. 1013-1016
    • Koh, J.Y.1    Suh, S.W.2    Gwag, B.J.3    He, Y.Y.4    Hsu, C.Y.5    Choi, D.W.6
  • 28
    • 84934270686 scopus 로고    scopus 로고
    • Hazard effects of nanoparticles in central nervous system: searching for biocompatible nanomaterials for drug delivery
    • PID: 26116398, COI: 1:CAS:528:DC%2BC2MXhtVyiu7fP
    • Leite PE, Pereira MR, Granjeiro JM (2015) Hazard effects of nanoparticles in central nervous system: searching for biocompatible nanomaterials for drug delivery. Toxicol In Vitro 29:1653–1660
    • (2015) Toxicol In Vitro , vol.29 , pp. 1653-1660
    • Leite, P.E.1    Pereira, M.R.2    Granjeiro, J.M.3
  • 29
    • 0025960330 scopus 로고
    • Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures
    • PID: 1670952, COI: 1:CAS:528:DyaK3MXnsFGksQ%3D%3D
    • Levi G, Patrizio M, Gallo V (1991) Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures. J Neurochem 56:199–206
    • (1991) J Neurochem , vol.56 , pp. 199-206
    • Levi, G.1    Patrizio, M.2    Gallo, V.3
  • 32
    • 0031194657 scopus 로고    scopus 로고
    • Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells
    • PID: 9225750, COI: 1:CAS:528:DyaK2sXkslOit7Y%3D
    • Manev H, Kharlamov E, Uz T, Mason RP, Cagnoli CM (1997) Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells. Exp Neurol 146:171–178
    • (1997) Exp Neurol , vol.146 , pp. 171-178
    • Manev, H.1    Kharlamov, E.2    Uz, T.3    Mason, R.P.4    Cagnoli, C.M.5
  • 33
    • 59649092943 scopus 로고    scopus 로고
    • 2+ accumulation contributes to synaptic failure, mitochondrial depolarization and cell death in an acute slice oxygen-glucose deprivation model of ischemia
    • PID: 19176819, COI: 1:CAS:528:DC%2BD1MXhs1Kqtrk%3D
    • 2+ accumulation contributes to synaptic failure, mitochondrial depolarization and cell death in an acute slice oxygen-glucose deprivation model of ischemia. J Neurosci 29:1105–1114
    • (2009) J Neurosci , vol.29 , pp. 1105-1114
    • Medvedeva, Y.V.1    Lin, B.2    Shuttleworth, C.W.3    Weiss, J.H.4
  • 34
    • 84862290800 scopus 로고    scopus 로고
    • Ion channels and zinc: mechanisms of neurotoxicity and neurodegeneration
    • Morris DR, Lavensonn CW (2012) Ion channels and zinc: mechanisms of neurotoxicity and neurodegeneration. J Toxicol ID: 785647
    • (2012) J Toxicol ID
    • Morris, D.R.1    Lavensonn, C.W.2
  • 35
    • 0028948696 scopus 로고
    • Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc
    • PID: 7882967, COI: 1:CAS:528:DyaK2MXktF2msrg%3D
    • Palmiter RD, Findley SD (1995) Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J 14:639–649
    • (1995) EMBO J , vol.14 , pp. 639-649
    • Palmiter, R.D.1    Findley, S.D.2
  • 36
    • 58149467940 scopus 로고    scopus 로고
    • Zinc at glutamatergic synapses
    • PID: 18353558, COI: 1:CAS:528:DC%2BD1MXns1yiug%3D%3D
    • Paoletti P, Vergnano AM, Barbour B, Casado M (2009) Zinc at glutamatergic synapses. Neuroscience 158:126–136
    • (2009) Neuroscience , vol.158 , pp. 126-136
    • Paoletti, P.1    Vergnano, A.M.2    Barbour, B.3    Casado, M.4
  • 37
    • 0031024717 scopus 로고    scopus 로고
    • Zinc and DNA fragmentation in keratinocyte apoptosis: its inhibitory effect in UVB irradiated cells
    • PID: 9043099, COI: 1:CAS:528:DyaK2sXmsVOnuw%3D%3D
    • Parat MO, Richard MJ, Pollet S, Hadjur C, Favie A, Béani JC (1997) Zinc and DNA fragmentation in keratinocyte apoptosis: its inhibitory effect in UVB irradiated cells. J Photochem Photobiol B 37:101–106
    • (1997) J Photochem Photobiol B , vol.37 , pp. 101-106
    • Parat, M.O.1    Richard, M.J.2    Pollet, S.3    Hadjur, C.4    Favie, A.5    Béani, J.C.6
  • 38
    • 77649338980 scopus 로고    scopus 로고
    • Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism
    • PID: 19969064, COI: 1:CAS:528:DC%2BC3cXjtVSgs7o%3D
    • Park EJ, Yi J, Kim Y, Choi K, Park K (2010) Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicol In Vitro 24:872–878
    • (2010) Toxicol In Vitro , vol.24 , pp. 872-878
    • Park, E.J.1    Yi, J.2    Kim, Y.3    Choi, K.4    Park, K.5
  • 39
    • 0023253615 scopus 로고
    • Zinc selectively blocks the action of N-methyl-d-aspartate on cortical neurons
    • PID: 2883728, COI: 1:CAS:528:DyaL2sXktFyhtbg%3D
    • Peters S, Koh J, Choi DW (1987) Zinc selectively blocks the action of N-methyl-d-aspartate on cortical neurons. Science 236:589–593
    • (1987) Science , vol.236 , pp. 589-593
    • Peters, S.1    Koh, J.2    Choi, D.W.3
  • 40
    • 79651472432 scopus 로고    scopus 로고
    • Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
    • PID: 21182908, COI: 1:CAS:528:DC%2BC3MXhvFeksLo%3D
    • Piao MJ, Kang KA, Lee IK, Kim HS, Kim S, Choi JY, Choi J, Hyun JW (2011) Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis. Toxicol Lett 201:92–100
    • (2011) Toxicol Lett , vol.201 , pp. 92-100
    • Piao, M.J.1    Kang, K.A.2    Lee, I.K.3    Kim, H.S.4    Kim, S.5    Choi, J.Y.6    Choi, J.7    Hyun, J.W.8
  • 41
    • 84893856723 scopus 로고    scopus 로고
    • The interactive roles of zinc and calcium in mitochondrial dysfunction and neurodegeneration
    • PID: 24127746, COI: 1:CAS:528:DC%2BC2cXitFWktLs%3D
    • Pivovarova NB, Stanika RI, Kazanina G, Villanueva I, Andrews SB (2014) The interactive roles of zinc and calcium in mitochondrial dysfunction and neurodegeneration. J Neurochem 128:592–602
    • (2014) J Neurochem , vol.128 , pp. 592-602
    • Pivovarova, N.B.1    Stanika, R.I.2    Kazanina, G.3    Villanueva, I.4    Andrews, S.B.5
  • 43
    • 0035869336 scopus 로고    scopus 로고
    • Mitochondria control ampa/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells
    • PID: 11245674, COI: 1:CAS:528:DC%2BD3MXjslClsbo%3D
    • Rego AC, Ward MW, Nicholls DG (2001) Mitochondria control ampa/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells. J Neurosci 21:1893–1901
    • (2001) J Neurosci , vol.21 , pp. 1893-1901
    • Rego, A.C.1    Ward, M.W.2    Nicholls, D.G.3
  • 44
    • 0027154162 scopus 로고
    • Effect of zinc supplementation on resistance of cultured human skin fibroblasts toward oxidant stress
    • PID: 7688532, COI: 1:CAS:528:DyaK3sXltFKis7s%3D
    • Richard MJ, Guiraud P, Leccia MT, Beani JC, Favier A (1993) Effect of zinc supplementation on resistance of cultured human skin fibroblasts toward oxidant stress. Biol Trace Elem Res 37:187–199
    • (1993) Biol Trace Elem Res , vol.37 , pp. 187-199
    • Richard, M.J.1    Guiraud, P.2    Leccia, M.T.3    Beani, J.C.4    Favier, A.5
  • 45
    • 1642310426 scopus 로고    scopus 로고
    • Prevention of catheter-related infections: the potential of a new nano-silver impregnated catheter
    • COI: 1:CAS:528:DC%2BD2cXisVehtLk%3D
    • Samuel U, Guggenbichler JP (2004) Prevention of catheter-related infections: the potential of a new nano-silver impregnated catheter. Int J Antimicrob Agent 23(Suppl 1):S75–S78
    • (2004) Int J Antimicrob Agent , vol.23 , pp. S75-S78
    • Samuel, U.1    Guggenbichler, J.P.2
  • 46
    • 84876677994 scopus 로고    scopus 로고
    • Nanosilver: application and novel aspects of toxicology
    • PID: 23344422, COI: 1:CAS:528:DC%2BC3sXhtlGmsrs%3D
    • Schluesener JK, Schluesener HJ (2013) Nanosilver: application and novel aspects of toxicology. Arch Toxicol 87:569–576
    • (2013) Arch Toxicol , vol.87 , pp. 569-576
    • Schluesener, J.K.1    Schluesener, H.J.2
  • 47
    • 0031466709 scopus 로고    scopus 로고
    • Measurement of intracellular free zinc in living cortical neurons: routes of entry
    • PID: 9391010, COI: 1:CAS:528:DyaK2sXotVWgsLg%3D
    • Sensi SL, Canzoniero LM, Yu SP, Ying HS, Koh JY, Kerchner GA, Choi DW (1997) Measurement of intracellular free zinc in living cortical neurons: routes of entry. J Neurosci 17:9554–9564
    • (1997) J Neurosci , vol.17 , pp. 9554-9564
    • Sensi, S.L.1    Canzoniero, L.M.2    Yu, S.P.3    Ying, H.S.4    Koh, J.Y.5    Kerchner, G.A.6    Choi, D.W.7
  • 48
    • 68249161469 scopus 로고    scopus 로고
    • Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches
    • PID: 19928185, COI: 1:CAS:528:DC%2BD1MXht1yrsbfN
    • Sharma HS, Ali SF, Hussain SM, Schlager JJ, Sharma A (2009) Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches. J Nanosci Nanotechnol 9:5055–5072
    • (2009) J Nanosci Nanotechnol , vol.9 , pp. 5055-5072
    • Sharma, H.S.1    Ali, S.F.2    Hussain, S.M.3    Schlager, J.J.4    Sharma, A.5
  • 49
    • 0034194361 scopus 로고    scopus 로고
    • Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis
    • PID: 10777777, COI: 1:CAS:528:DC%2BD3cXivFKht78%3D
    • Sheline CT, Behrens MM, Choi DW (2000) Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis. J Neurosci 20:3139–3146
    • (2000) J Neurosci , vol.20 , pp. 3139-3146
    • Sheline, C.T.1    Behrens, M.M.2    Choi, D.W.3
  • 50
    • 84864435661 scopus 로고    scopus 로고
    • Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles
    • PID: 22820426, COI: 1:CAS:528:DC%2BC38Xht1SktLrI
    • Singh RP, Ramarao P (2012) Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles. Toxicol Lett 213:249–259
    • (2012) Toxicol Lett , vol.213 , pp. 249-259
    • Singh, R.P.1    Ramarao, P.2
  • 51
    • 84862572710 scopus 로고    scopus 로고
    • Is the zinc neuroprotective effect caused by prevention of intracellular zinc accumulation?
    • PID: 23214289
    • Sobieszczańska M, Tubek S, Szyguła R, Bunio A (2012) Is the zinc neuroprotective effect caused by prevention of intracellular zinc accumulation? Adv Clin Exp Med 21:245–248
    • (2012) Adv Clin Exp Med , vol.21 , pp. 245-248
    • Sobieszczańska, M.1    Tubek, S.2    Szyguła, R.3    Bunio, A.4
  • 52
    • 84912025296 scopus 로고    scopus 로고
    • Markers of oxidative stress in hepatopancreas of crayfish (Orconectes limosus, Raf.) experimentally exposed to nanosilver
    • PID: 23460582, COI: 1:CAS:528:DC%2BC3sXjsFOgtb0%3D
    • Struzynski W, Dabrowska-Bouta B, Grygorowicz T, Zieminska E, Struzynska L (2014) Markers of oxidative stress in hepatopancreas of crayfish (Orconectes limosus, Raf.) experimentally exposed to nanosilver. Environ Toxicol 29:1283–1291
    • (2014) Environ Toxicol , vol.29 , pp. 1283-1291
    • Struzynski, W.1    Dabrowska-Bouta, B.2    Grygorowicz, T.3    Zieminska, E.4    Struzynska, L.5
  • 53
    • 0025138527 scopus 로고
    • Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat
    • PID: 2330128
    • Tønder N, Johansen FF, Frederickson CJ, Zimmer J, Diemer NH (1990) Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neurosci Lett 109:247–252
    • (1990) Neurosci Lett , vol.109 , pp. 247-252
    • Tønder, N.1    Johansen, F.F.2    Frederickson, C.J.3    Zimmer, J.4    Diemer, N.H.5
  • 54
    • 0034221295 scopus 로고    scopus 로고
    • Interactions between carnosine and zinc and copper: implications for neuromodulation and neuroprotection
    • COI: 1:CAS:528:DC%2BD3cXlvFOlsbk%3D
    • Trombley PQ, Horning MS, Blakemore LJ (2000) Interactions between carnosine and zinc and copper: implications for neuromodulation and neuroprotection. Biochemistry (Mosc) 65:807–816
    • (2000) Biochemistry (Mosc) , vol.65 , pp. 807-816
    • Trombley, P.Q.1    Horning, M.S.2    Blakemore, L.J.3
  • 55
    • 0030839480 scopus 로고    scopus 로고
    • Expression of zinc transporter gene, ZnT-1, is induced after transient forebrain ischemia in the gerbil
    • PID: 9254680, COI: 1:CAS:528:DyaK2sXlsleisr4%3D
    • Tsuda M, Imaizumi K, Katayama T, Kitagawa K, Wanaka A, Tohyama M, Takagi T (1997) Expression of zinc transporter gene, ZnT-1, is induced after transient forebrain ischemia in the gerbil. J Neurosci 17:6678–6684
    • (1997) J Neurosci , vol.17 , pp. 6678-6684
    • Tsuda, M.1    Imaizumi, K.2    Katayama, T.3    Kitagawa, K.4    Wanaka, A.5    Tohyama, M.6    Takagi, T.7
  • 56
    • 0027394031 scopus 로고
    • The biochemical basis of zinc physiology
    • PID: 8419966, COI: 1:CAS:528:DyaK3sXhvVyhtrY%3D
    • Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79–118
    • (1993) Physiol Rev , vol.73 , pp. 79-118
    • Vallee, B.L.1    Falchuk, K.H.2
  • 57
    • 0023160323 scopus 로고
    • 2+ antagonize NMDA and GABA responses of hippocampal neurons
    • PID: 3039375, COI: 1:CAS:528:DyaL2sXlt1OrsrY%3D
    • 2+ antagonize NMDA and GABA responses of hippocampal neurons. Nature 328:640–643
    • (1987) Nature , vol.328 , pp. 640-643
    • Westbrook, G.L.1    Mayer, M.L.2
  • 58
    • 84878042941 scopus 로고    scopus 로고
    • Silver nanoparticle exposure attenuates the viability of rat cerebellum granule cells through apoptosis coupled to oxidative stress
    • PID: 23427069, COI: 1:CAS:528:DC%2BC3sXivVKjsLw%3D
    • Yin N, Liu Q, Liu J, He B, Cui L, Li Z, Yun Z, Qu G, Liu S, Zhou Q, Jiang G (2013) Silver nanoparticle exposure attenuates the viability of rat cerebellum granule cells through apoptosis coupled to oxidative stress. Small 9:1831–1841
    • (2013) Small , vol.9 , pp. 1831-1841
    • Yin, N.1    Liu, Q.2    Liu, J.3    He, B.4    Cui, L.5    Li, Z.6    Yun, Z.7    Qu, G.8    Liu, S.9    Zhou, Q.10    Jiang, G.11
  • 60
    • 77957262510 scopus 로고    scopus 로고
    • Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins
    • PID: 20696200, COI: 1:CAS:528:DC%2BC3cXht1CgurvE
    • Zieminska E, Toczylowska B, Stafiej A, Lazarewicz JW (2010) Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins. Toxicology 276:154–163
    • (2010) Toxicology , vol.276 , pp. 154-163
    • Zieminska, E.1    Toczylowska, B.2    Stafiej, A.3    Lazarewicz, J.W.4
  • 61
    • 84890283664 scopus 로고    scopus 로고
    • The role of the glutamatergic NMDA receptor in nanosilver-evoked neurotoxicity in primary cultures of cerebellar granule cells
    • COI: 1:CAS:528:DC%2BC2cXisFajsg%3D%3D
    • Zieminska E, Stafiej A, Strużyńska L (2014) The role of the glutamatergic NMDA receptor in nanosilver-evoked neurotoxicity in primary cultures of cerebellar granule cells. Toxicol 315:38–48
    • (2014) Toxicol , vol.315 , pp. 38-48
    • Zieminska, E.1    Stafiej, A.2    Strużyńska, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.