Topical formulation containing naringenin: Efficacy against ultraviolet B irradiation-induced skin inflammation and oxidative stress in mice

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Martinez, Renata M ^a   Pinho Ribeiro, Felipe A ^a   Steffen, Vinicius S ^a   Silva, Thais C C ^a   Caviglione, Carla V ^a   Bottura, Carolina ^a   Fonseca, Maria J V ^b   Vicentini, Fabiana T M C ^c   Vignoli, Josiane A ^a   Baracat, Marcela M ^a   Georgetti, Sandra R ^a   Verri, Waldiceu A ^a   Casagrande, Rubia ^a  

^a STATE UNIVERSITY OF LONDRINA   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FARMACORE BIOTECNOLOGIA LTDA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NARINGENIN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; 2,2'-AZINO-DI-(3-ETHYLBENZOTHIAZOLINE)-6-SULFONIC ACID; ANTIOXIDANT; BENZOTHIAZOLE DERIVATIVE; FLAVANONE DERIVATIVE; GLUTATHIONE PEROXIDASE; HYDROXYL RADICAL; IL10 PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; NFE2L2 PROTEIN, MOUSE; SULFONIC ACID DERIVATIVE; SUPEROXIDE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG STABILITY; ENZYME ACTIVITY; GENE EXPRESSION; GLUTATHIONE PEROXIDASE 1 GENE; GLUTATHIONE REDUCTASE GENE; HEME OXYGENASE 1 GENE; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; SKIN DEFECT; SKIN EDEMA; SKIN PROTECTION; TRANSCRIPTION FACTOR NRF2 GENE; ULTRAVIOLET B RADIATION; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CUTANEOUS DRUG ADMINISTRATION; DRUG EFFECTS; EDEMA; GENETICS; HAIRLESS MOUSE; INFLAMMATION; METABOLISM; PATHOLOGY; RADIATION RESPONSE; SKIN; ULTRAVIOLET RADIATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIOXIDANTS; BENZOTHIAZOLES; CATALASE; EDEMA; FLAVANONES; GENE EXPRESSION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE-1; HYDROXYL RADICAL; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPID PEROXIDATION; MICE; MICE, HAIRLESS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SKIN; SULFONIC ACIDS; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

EID: 84954179895     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0146296     Document Type: Article

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