Silibinin prevents ultraviolent radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis

Carcinogenesis

Volumn 25, Issue 8, 2004, Pages 1459-1465

  Dhanalakshmi, Sivanandhan ^a   Mallikarjuna, G U ^a   Singh, Rana P ^a   Agarwal, Rajesh ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; PROTEIN P21; PROTEIN P53; SILIBININ; THYMINE; ANTINEOPLASTIC AGENT; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PYRIMIDINE DIMER; SILYMARIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIMERIZATION; DNA DAMAGE; DRUG EFFICACY; DRUG MECHANISM; EPIDERMIS CELL; FEMALE; MOUSE; NICK END LABELING; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RADIATION INJURY; RADIATION PROTECTION; SKIN DEFECT; STAINING; SUNBURN; ULTRAVIOLET RADIATION; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL DIVISION; CHEMISTRY; DRUG EFFECT; EPIDERMIS; HAIRLESS MOUSE; IMMUNOHISTOCHEMISTRY; METABOLISM; RADIATION EXPOSURE; SKIN; SKIN TUMOR; TIME;

ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DIMERIZATION; DNA DAMAGE; EPIDERMIS; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICE, INBRED HRS; MODELS, BIOLOGICAL; PROLIFERATING CELL NUCLEAR ANTIGEN; PYRIMIDINE DIMERS; SILYMARIN; SKIN; SKIN NEOPLASMS; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 4344650392     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh152     Document Type: Article

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