-
1
-
-
0037531126
-
Oxaliplatin for colorectal cancer in the United States: Better late than never
-
12775727 1:CAS:528:DC%2BD2cXpsVGqt7s%3D
-
Chau I, Cunningham D (2003) Oxaliplatin for colorectal cancer in the United States: better late than never. J Clin Oncol 21:2049-2051
-
(2003)
J Clin Oncol
, vol.21
, pp. 2049-2051
-
-
Chau, I.1
Cunningham, D.2
-
2
-
-
2542615200
-
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators 15175436 1:CAS:528:DC%2BD2cXks1Gjt78%3D
-
Andre T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, Topham C, Zaninelli M, Clingan P, Bridgewater J, Tabah-Fisch I, de Gramont A, Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators (2004) Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 350:2343-2351
-
(2004)
N Engl J Med
, vol.350
, pp. 2343-2351
-
-
Andre, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
Navarro, M.4
Tabernero, J.5
Hickish, T.6
Topham, C.7
Zaninelli, M.8
Clingan, P.9
Bridgewater, J.10
Tabah-Fisch, I.11
De Gramont, A.12
-
3
-
-
0031755917
-
Search for the optimal schedule for the oxaliplatin/5-fluorouracil association modulated or not by folinic acid: Preclinical data
-
9796987 1:CAS:528:DyaK1cXmvFykurk%3D
-
Fischel JL, Etienne MC, Formento P, Milano G (1998) Search for the optimal schedule for the oxaliplatin/5-fluorouracil association modulated or not by folinic acid: preclinical data. Clin Cancer Res 4:2529-2535
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2529-2535
-
-
Fischel, J.L.1
Etienne, M.C.2
Formento, P.3
Milano, G.4
-
4
-
-
38449107093
-
Capecitabine plus oxaliplatin and irinotecan regimen every other week: A phase I/II study in first-line treatment of metastatic colorectal cancer
-
17823385 1:STN:280:DC%2BD2sjktFemsw%3D%3D
-
Bajetta E, Celio L, Ferrario E, Di Bartolomeo M, Denaro A, Dotti K, Mancin M, Bajetta R, Colombo A, Pusceddu S (2007) Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer. Ann Oncol 18:1810-1816
-
(2007)
Ann Oncol
, vol.18
, pp. 1810-1816
-
-
Bajetta, E.1
Celio, L.2
Ferrario, E.3
Di Bartolomeo, M.4
Denaro, A.5
Dotti, K.6
Mancin, M.7
Bajetta, R.8
Colombo, A.9
Pusceddu, S.10
-
5
-
-
3042725384
-
Oxaliplatin plus oral fluoropyrimidines in colorectal cancer
-
15212704 1:CAS:528:DC%2BD2cXls1Sjsr4%3D
-
Grothey A, Goetz MP (2004) Oxaliplatin plus oral fluoropyrimidines in colorectal cancer. Clin Colorectal Cancer 4(Suppl 1):S37-S42
-
(2004)
Clin Colorectal Cancer
, vol.4
, pp. S37-S42
-
-
Grothey, A.1
Goetz, M.P.2
-
6
-
-
0031741679
-
Oxaliplatin: A review of preclinical and clinical studies
-
9834817 1:STN:280:DyaK1M%2FltFyrsA%3D%3D
-
Raymond E, Chaney SG, Taamma A, Cvitkovic E (1998) Oxaliplatin: a review of preclinical and clinical studies. Ann Oncol 9:1053-1071
-
(1998)
Ann Oncol
, vol.9
, pp. 1053-1071
-
-
Raymond, E.1
Chaney, S.G.2
Taamma, A.3
Cvitkovic, E.4
-
7
-
-
0029904811
-
The role of DNA mismatch repair in platinum drug resistance
-
8895738 1:CAS:528:DyaK28XmsFygsbg%3D
-
Fink D, Nebel S, Aebi S, Zheng H, Cenni B, Nehme A, Christen RD, Howell SB (1996) The role of DNA mismatch repair in platinum drug resistance. Cancer Res 56:4881-4886
-
(1996)
Cancer Res
, vol.56
, pp. 4881-4886
-
-
Fink, D.1
Nebel, S.2
Aebi, S.3
Zheng, H.4
Cenni, B.5
Nehme, A.6
Christen, R.D.7
Howell, S.B.8
-
8
-
-
33747152564
-
Different accumulation of cisplatin, oxaliplatin and JM216 in sensitive and cisplatin-resistant human cervical tumour cells
-
16844093 1:CAS:528:DC%2BD28XotlWgt7s%3D
-
Martelli L, Di Mario F, Ragazzi E, Apostoli P, Leone R, Perego P, Fumagalli G (2006) Different accumulation of cisplatin, oxaliplatin and JM216 in sensitive and cisplatin-resistant human cervical tumour cells. Biochem Pharmacol 72:693-700
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 693-700
-
-
Martelli, L.1
Di Mario, F.2
Ragazzi, E.3
Apostoli, P.4
Leone, R.5
Perego, P.6
Fumagalli, G.7
-
9
-
-
0031864830
-
Oxaliplatin: Mechanism of action and antineoplastic activity
-
9609103 1:CAS:528:DyaK1cXjvVCkt70%3D
-
Raymond E, Faivre S, Woynarowski JM, Chaney SG (1998) Oxaliplatin: mechanism of action and antineoplastic activity. Semin Oncol 25:4-12
-
(1998)
Semin Oncol
, vol.25
, pp. 4-12
-
-
Raymond, E.1
Faivre, S.2
Woynarowski, J.M.3
Chaney, S.G.4
-
10
-
-
70349381479
-
Strategies to improve the efficacy of platinum compounds
-
19601785 1:CAS:528:DC%2BD1MXptVahs74%3D
-
Cossa G, Gatti L, Zunino F, Perego P (2009) Strategies to improve the efficacy of platinum compounds. Curr Med Chem 16:2355-2365
-
(2009)
Curr Med Chem
, vol.16
, pp. 2355-2365
-
-
Cossa, G.1
Gatti, L.2
Zunino, F.3
Perego, P.4
-
11
-
-
0032529467
-
The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts
-
9721864 1:CAS:528:DyaK1cXlsFajtrY%3D
-
Vaisman A, Varchenko M, Umar A, Kunkel TA, Risinger JI, Barrett JC, Hamilton TC, Chaney SG (1998) The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts. Cancer Res 58:3579-3585
-
(1998)
Cancer Res
, vol.58
, pp. 3579-3585
-
-
Vaisman, A.1
Varchenko, M.2
Umar, A.3
Kunkel, T.A.4
Risinger, J.I.5
Barrett, J.C.6
Hamilton, T.C.7
Chaney, S.G.8
-
12
-
-
0033016378
-
Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells
-
10098743 1:CAS:528:DyaK1MXhvVKqtb8%3D 2362240
-
Nehme A, Baskaran R, Nebel S, Fink D, Howell SB, Wang JY, Christen RD (1999) Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells. Br J Cancer 79:1104-1110
-
(1999)
Br J Cancer
, vol.79
, pp. 1104-1110
-
-
Nehme, A.1
Baskaran, R.2
Nebel, S.3
Fink, D.4
Howell, S.B.5
Wang, J.Y.6
Christen, R.D.7
-
13
-
-
33846057130
-
Calreticulin exposure dictates the immunogenicity of cancer cell death
-
17187072 1:CAS:528:DC%2BD2sXhvFWisw%3D%3D
-
Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, Castedo M, Mignot G, Panaretakis T, Casares N, Metivier D, Larochette N, van Endert P, Ciccosanti F, Piacentini M, Zitvogel L, Kroemer G (2007) Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med 13:54-61
-
(2007)
Nat Med
, vol.13
, pp. 54-61
-
-
Obeid, M.1
Tesniere, A.2
Ghiringhelli, F.3
Fimia, G.M.4
Apetoh, L.5
Perfettini, J.L.6
Castedo, M.7
Mignot, G.8
Panaretakis, T.9
Casares, N.10
Metivier, D.11
Larochette, N.12
Van Endert, P.13
Ciccosanti, F.14
Piacentini, M.15
Zitvogel, L.16
Kroemer, G.17
-
14
-
-
0033962280
-
Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs
-
10732773 1:CAS:528:DC%2BD3cXhs1yhtbs%3D 2374394
-
Screnci D, McKeage MJ, Galettis P, Hambley TW, Palmer BD, Baguley BC (2000) Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs. Br J Cancer 82:966-972
-
(2000)
Br J Cancer
, vol.82
, pp. 966-972
-
-
Screnci, D.1
McKeage, M.J.2
Galettis, P.3
Hambley, T.W.4
Palmer, B.D.5
Baguley, B.C.6
-
15
-
-
84874625728
-
Polymorphic transporters and platinum pharmacodynamics
-
22986709 1:CAS:528:DC%2BC3sXns1Ghtb0%3D 3705946
-
Sprowl JA, Ness RA, Sparreboom A (2013) Polymorphic transporters and platinum pharmacodynamics. Drug Metab Pharmacokinet 28:19-27
-
(2013)
Drug Metab Pharmacokinet
, vol.28
, pp. 19-27
-
-
Sprowl, J.A.1
Ness, R.A.2
Sparreboom, A.3
-
16
-
-
33751168746
-
Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)
-
16914559 1:CAS:528:DC%2BD28XhtFOkurjK
-
Yonezawa A, Masuda S, Yokoo S, Katsura T, Inui K (2006) Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family). J Pharmacol Exp Ther 319:879-886
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 879-886
-
-
Yonezawa, A.1
Masuda, S.2
Yokoo, S.3
Katsura, T.4
Inui, K.5
-
17
-
-
34250764918
-
Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity
-
17582384 1:CAS:528:DC%2BD2sXntFamurc%3D
-
Yokoo S, Yonezawa A, Masuda S, Fukatsu A, Katsura T, Inui K (2007) Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity. Biochem Pharmacol 74:477-487
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 477-487
-
-
Yokoo, S.1
Yonezawa, A.2
Masuda, S.3
Fukatsu, A.4
Katsura, T.5
Inui, K.6
-
18
-
-
33749037182
-
Organic cation transporters are determinants of oxaliplatin cytotoxicity
-
16951202 1:CAS:528:DC%2BD28XovF2ht7w%3D 2775093
-
Zhang S, Lovejoy KS, Shima JE, Lagpacan LL, Shu Y, Lapuk A, Chen Y, Komori T, Gray JW, Chen X, Lippard SJ, Giacomini KM (2006) Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res 66:8847-8857
-
(2006)
Cancer Res
, vol.66
, pp. 8847-8857
-
-
Zhang, S.1
Lovejoy, K.S.2
Shima, J.E.3
Lagpacan, L.L.4
Shu, Y.5
Lapuk, A.6
Chen, Y.7
Komori, T.8
Gray, J.W.9
Chen, X.10
Lippard, S.J.11
Giacomini, K.M.12
-
19
-
-
79952485264
-
Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice
-
21104302 1:CAS:528:DC%2BC3cXhsVGru77F 3040319
-
Li S, Chen Y, Zhang S, More SS, Huang X, Giacomini KM (2011) Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice. Pharm Res 28:610-625
-
(2011)
Pharm Res
, vol.28
, pp. 610-625
-
-
Li, S.1
Chen, Y.2
Zhang, S.3
More, S.S.4
Huang, X.5
Giacomini, K.M.6
-
20
-
-
84954056045
-
High expression of organic anion transporter 2 and organic cation transporter 2 is an independent predictor of good outcomes in patients with metastatic colorectal cancer treated with FOLFOX-based chemotherapy
-
25232494 1:CAS:528:DC%2BC2cXhvVOru7bM 4163617
-
Tashiro A, Tatsumi S, Takeda R, Naka A, Matsuoka H, Hashimoto Y, Hatta K, Maeda K, Kamoshida S (2014) High expression of organic anion transporter 2 and organic cation transporter 2 is an independent predictor of good outcomes in patients with metastatic colorectal cancer treated with FOLFOX-based chemotherapy. Am J Cancer Res 4:528-536
-
(2014)
Am J Cancer Res
, vol.4
, pp. 528-536
-
-
Tashiro, A.1
Tatsumi, S.2
Takeda, R.3
Naka, A.4
Matsuoka, H.5
Hashimoto, Y.6
Hatta, K.7
Maeda, K.8
Kamoshida, S.9
-
21
-
-
79960525836
-
Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons
-
21606177 1:CAS:528:DC%2BC3MXpvFemu7s%3D
-
Jong NN, Nakanishi T, Liu JJ, Tamai I, McKeage MJ (2011) Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons. J Pharmacol Exp Ther 338:537-547
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 537-547
-
-
Jong, N.N.1
Nakanishi, T.2
Liu, J.J.3
Tamai, I.4
McKeage, M.J.5
-
22
-
-
59449104509
-
The role of the mammalian copper transporter 1 in the cellular accumulation of platinum-based drugs
-
18996970 1:CAS:528:DC%2BD1MXhtlGitrk%3D 2684896
-
Larson CA, Blair BG, Safaei R, Howell SB (2009) The role of the mammalian copper transporter 1 in the cellular accumulation of platinum-based drugs. Mol Pharmacol 75:324-330
-
(2009)
Mol Pharmacol
, vol.75
, pp. 324-330
-
-
Larson, C.A.1
Blair, B.G.2
Safaei, R.3
Howell, S.B.4
-
23
-
-
68149174943
-
Neuronal expression of copper transporter 1 in rat dorsal root ganglia: Association with platinum neurotoxicity
-
19466412 1:CAS:528:DC%2BD1MXptFCks7o%3D
-
Liu JJ, Jamieson SM, Subramaniam J, Ip V, Jong NN, Mercer JF, McKeage MJ (2009) Neuronal expression of copper transporter 1 in rat dorsal root ganglia: association with platinum neurotoxicity. Cancer Chemother Pharmacol 64:847-856
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 847-856
-
-
Liu, J.J.1
Jamieson, S.M.2
Subramaniam, J.3
Ip, V.4
Jong, N.N.5
Mercer, J.F.6
McKeage, M.J.7
-
24
-
-
67650359894
-
Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin
-
19509135 1:CAS:528:DC%2BD1MXnvFajsbs%3D 2862640
-
Blair BG, Larson CA, Safaei R, Howell SB (2009) Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin. Clin Cancer Res 15:4312-4321
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4312-4321
-
-
Blair, B.G.1
Larson, C.A.2
Safaei, R.3
Howell, S.B.4
-
25
-
-
3042663282
-
Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B
-
15213293 1:CAS:528:DC%2BD2cXlsVOjurw%3D
-
Samimi G, Katano K, Holzer AK, Safaei R, Howell SB (2004) Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B. Mol Pharmacol 66:25-32
-
(2004)
Mol Pharmacol
, vol.66
, pp. 25-32
-
-
Samimi, G.1
Katano, K.2
Holzer, A.K.3
Safaei, R.4
Howell, S.B.5
-
26
-
-
65649088246
-
Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy
-
19296535 1:CAS:528:DC%2BD1MXltlCgtLY%3D
-
Martinez-Balibrea E, Martinez-Cardus A, Musulen E, Gines A, Manzano JL, Aranda E, Plasencia C, Neamati N, Abad A (2009) Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy. Int J Cancer 124:2905-2910
-
(2009)
Int J Cancer
, vol.124
, pp. 2905-2910
-
-
Martinez-Balibrea, E.1
Martinez-Cardus, A.2
Musulen, E.3
Gines, A.4
Manzano, J.L.5
Aranda, E.6
Plasencia, C.7
Neamati, N.8
Abad, A.9
-
27
-
-
77956476273
-
Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue
-
Ip V, Liu JJ, Mercer JF, McKeage MJ (2010) Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue. Mol Pain 6:53-8069-6-53
-
(2010)
Mol Pain
, vol.6
-
-
Ip, V.1
Liu, J.J.2
Mercer, J.F.3
McKeage, M.J.4
-
28
-
-
70349572622
-
ABC transporters as potential targets for modulation of drug resistance
-
19689406 1:CAS:528:DC%2BD1MXhtVWnt7jP
-
Gatti L, Beretta GL, Cossa G, Zunino F, Perego P (2009) ABC transporters as potential targets for modulation of drug resistance. Mini Rev Med Chem 9:1102-1112
-
(2009)
Mini Rev Med Chem
, vol.9
, pp. 1102-1112
-
-
Gatti, L.1
Beretta, G.L.2
Cossa, G.3
Zunino, F.4
Perego, P.5
-
29
-
-
9544233652
-
A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
-
8797578 1:CAS:528:DyaK28XlslGgsbg%3D
-
Taniguchi K, Wada M, Kohno K, Nakamura T, Kawabe T, Kawakami M, Kagotani K, Okumura K, Akiyama S, Kuwano M (1996) A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res 56:4124-4129
-
(1996)
Cancer Res
, vol.56
, pp. 4124-4129
-
-
Taniguchi, K.1
Wada, M.2
Kohno, K.3
Nakamura, T.4
Kawabe, T.5
Kawakami, M.6
Kagotani, K.7
Okumura, K.8
Akiyama, S.9
Kuwano, M.10
-
30
-
-
35948997380
-
Predictive factors of oxaliplatin neurotoxicity: The involvement of the oxalate outcome pathway
-
17975148 1:CAS:528:DC%2BD2sXht1Cgtb%2FL
-
Gamelin L, Capitain O, Morel A, Dumont A, Traore S, le Anne B, Gilles S, Boisdron-Celle M, Gamelin E (2007) Predictive factors of oxaliplatin neurotoxicity: the involvement of the oxalate outcome pathway. Clin Cancer Res 13:6359-6368
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6359-6368
-
-
Gamelin, L.1
Capitain, O.2
Morel, A.3
Dumont, A.4
Traore, S.5
Le Anne, B.6
Gilles, S.7
Boisdron-Celle, M.8
Gamelin, E.9
-
31
-
-
0034046035
-
Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas
-
10873092 1:CAS:528:DC%2BD3cXksVGhsLg%3D
-
Hinoshita E, Uchiumi T, Taguchi K, Kinukawa N, Tsuneyoshi M, Maehara Y, Sugimachi K, Kuwano M (2000) Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas. Clin Cancer Res 6:2401-2407
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2401-2407
-
-
Hinoshita, E.1
Uchiumi, T.2
Taguchi, K.3
Kinukawa, N.4
Tsuneyoshi, M.5
Maehara, Y.6
Sugimachi, K.7
Kuwano, M.8
-
32
-
-
84866103307
-
Lack of association between expression of MRP2 and early relapse of colorectal cancer in patients receiving FOLFOX-4 chemotherapy
-
23162618 1:CAS:528:DC%2BC38Xhs1ygtb%2FI 3499608
-
Mirakhorli M, Shayanfar N, Rahman SA, Rosli R, Abdullah S, Khoshzaban A (2012) Lack of association between expression of MRP2 and early relapse of colorectal cancer in patients receiving FOLFOX-4 chemotherapy. Oncol Lett 4:893-897
-
(2012)
Oncol Lett
, vol.4
, pp. 893-897
-
-
Mirakhorli, M.1
Shayanfar, N.2
Rahman, S.A.3
Rosli, R.4
Abdullah, S.5
Khoshzaban, A.6
-
33
-
-
84925285641
-
What do drug transporters really do?
-
25475361 1:CAS:528:DC%2BC2cXitVClu7rN
-
Nigam SK (2015) What do drug transporters really do? Nat Rev Drug Discov 14:29-44
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 29-44
-
-
Nigam, S.K.1
-
34
-
-
75149143363
-
ABC transporters in cancer: More than just drug efflux pumps
-
20075923 1:CAS:528:DC%2BC3cXlvFGlsQ%3D%3D
-
Fletcher JI, Haber M, Henderson MJ, Norris MD (2010) ABC transporters in cancer: more than just drug efflux pumps. Nat Rev Cancer 10:147-156
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 147-156
-
-
Fletcher, J.I.1
Haber, M.2
Henderson, M.J.3
Norris, M.D.4
-
36
-
-
70349759344
-
Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy
-
19622348 1:CAS:528:DC%2BD1MXht1GmsbzE
-
Theile D, Grebhardt S, Haefeli WE, Weiss J (2009) Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy. Biochem Pharmacol 78:1366-1373
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1366-1373
-
-
Theile, D.1
Grebhardt, S.2
Haefeli, W.E.3
Weiss, J.4
-
37
-
-
84882942352
-
Defining the role of MRP-mediated efflux and glutathione in detoxification of oxaliplatin
-
23923647 1:CAS:528:DC%2BC3sXht1Ohu7jL
-
Mohn C, Hacker HG, Hilger RA, Gutschow M, Jaehde U (2013) Defining the role of MRP-mediated efflux and glutathione in detoxification of oxaliplatin. Pharmazie 68:622-627
-
(2013)
Pharmazie
, vol.68
, pp. 622-627
-
-
Mohn, C.1
Hacker, H.G.2
Hilger, R.A.3
Gutschow, M.4
Jaehde, U.5
-
38
-
-
77954936807
-
Contribution of glutathione and MRP-mediated efflux to intracellular oxaliplatin accumulation
-
20557839 1:STN:280:DC%2BC3crhtlCrtQ%3D%3D
-
Mohn C, Kalayda GV, Hacker HG, Gutschow M, Metzger S, Jaehde U (2010) Contribution of glutathione and MRP-mediated efflux to intracellular oxaliplatin accumulation. Int J Clin Pharmacol Ther 48:445-447
-
(2010)
Int J Clin Pharmacol Ther
, vol.48
, pp. 445-447
-
-
Mohn, C.1
Kalayda, G.V.2
Hacker, H.G.3
Gutschow, M.4
Metzger, S.5
Jaehde, U.6
-
39
-
-
1642453792
-
Molecular determinants of the cytotoxicity of platinum compounds: The contribution of in silico research
-
14729645 1:CAS:528:DC%2BD2cXkslyrtw%3D%3D
-
Vekris A, Meynard D, Haaz MC, Bayssas M, Bonnet J, Robert J (2004) Molecular determinants of the cytotoxicity of platinum compounds: the contribution of in silico research. Cancer Res 64:356-362
-
(2004)
Cancer Res
, vol.64
, pp. 356-362
-
-
Vekris, A.1
Meynard, D.2
Haaz, M.C.3
Bayssas, M.4
Bonnet, J.5
Robert, J.6
-
40
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
15789122 1:CAS:528:DC%2BD2MXivVart7c%3D
-
Wang D, Lippard SJ (2005) Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 4:307-320
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
42
-
-
84954067271
-
Lessons for the NCI panel and clinical correlates
-
A. Bonetti R. Leone S.B. Howell (eds) 2009 Humana Press New York
-
Robert J, Laurand A, Meynard D, Le Morvan V (2009) Lessons for the NCI panel and clinical correlates. In: Bonetti A, Leone R, Howell SB (eds) Platinum and other heavy metal compounds in cancer chemotherapy, 2009th edn. Humana Press, New York, pp 149-155
-
(2009)
Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy
, pp. 149-155
-
-
Robert, J.1
Laurand, A.2
Meynard, D.3
Le Morvan, V.4
-
43
-
-
0034705031
-
Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin
-
10811891 1:CAS:528:DC%2BD3cXjvFakt7o%3D 18508
-
He Q, Liang CH, Lippard SJ (2000) Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin. Proc Natl Acad Sci USA 97:5768-5772
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5768-5772
-
-
He, Q.1
Liang, C.H.2
Lippard, S.J.3
-
44
-
-
0035866336
-
Transcriptional activation of the human HMG1 gene in cisplatin-resistant human cancer cells
-
11245470 1:CAS:528:DC%2BD3MXhvVelur4%3D
-
Nagatani G, Nomoto M, Takano H, Ise T, Kato K, Imamura T, Izumi H, Makishima K, Kohno K (2001) Transcriptional activation of the human HMG1 gene in cisplatin-resistant human cancer cells. Cancer Res 61:1592-1597
-
(2001)
Cancer Res
, vol.61
, pp. 1592-1597
-
-
Nagatani, G.1
Nomoto, M.2
Takano, H.3
Ise, T.4
Kato, K.5
Imamura, T.6
Izumi, H.7
Makishima, K.8
Kohno, K.9
-
45
-
-
0034724922
-
The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta
-
10777605 1:CAS:528:DC%2BD3cXjtVaqs74%3D
-
Vaisman A, Chaney SG (2000) The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta. J Biol Chem 275:13017-13025
-
(2000)
J Biol Chem
, vol.275
, pp. 13017-13025
-
-
Vaisman, A.1
Chaney, S.G.2
-
46
-
-
0034712656
-
Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta
-
10769112 1:CAS:528:DC%2BD3cXitVGns74%3D
-
Vaisman A, Masutani C, Hanaoka F, Chaney SG (2000) Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. Biochemistry 39:4575-4580
-
(2000)
Biochemistry
, vol.39
, pp. 4575-4580
-
-
Vaisman, A.1
Masutani, C.2
Hanaoka, F.3
Chaney, S.G.4
-
47
-
-
27544489816
-
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage
-
16267001 1:CAS:528:DC%2BD2MXhtFKktLzM
-
Albertella MR, Green CM, Lehmann AR, O'Connor MJ (2005) A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Cancer Res 65:9799-9806
-
(2005)
Cancer Res
, vol.65
, pp. 9799-9806
-
-
Albertella, M.R.1
Green, C.M.2
Lehmann, A.R.3
O'Connor, M.J.4
-
48
-
-
84861434605
-
DNA polymerase zeta is a major determinant of resistance to platinum-based chemotherapeutic agents
-
22387291 1:CAS:528:DC%2BC38XotlWmtbs%3D 3362893
-
Sharma S, Shah NA, Joiner AM, Roberts KH, Canman CE (2012) DNA polymerase zeta is a major determinant of resistance to platinum-based chemotherapeutic agents. Mol Pharmacol 81:778-787
-
(2012)
Mol Pharmacol
, vol.81
, pp. 778-787
-
-
Sharma, S.1
Shah, N.A.2
Joiner, A.M.3
Roberts, K.H.4
Canman, C.E.5
-
49
-
-
75149151363
-
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy
-
19838217 1:CAS:528:DC%2BD1MXht1OgsrrL
-
Yang J, Parsons J, Nicolay NH, Caporali S, Harrington CF, Singh R, Finch D, D'Atri S, Farmer PB, Johnston PG, McKenna WG, Dianov G, Sharma RA (2010) Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy. Oncogene 29:463-468
-
(2010)
Oncogene
, vol.29
, pp. 463-468
-
-
Yang, J.1
Parsons, J.2
Nicolay, N.H.3
Caporali, S.4
Harrington, C.F.5
Singh, R.6
Finch, D.7
D'Atri, S.8
Farmer, P.B.9
Johnston, P.G.10
McKenna, W.G.11
Dianov, G.12
Sharma, R.A.13
-
50
-
-
78649334377
-
DNA polymerase eta protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy
-
Teng KY, Qiu MZ, Li ZH, Luo HY, Zeng ZL, Luo RZ, Zhang HZ, Wang ZQ, Li YH, Xu RH (2010) DNA polymerase eta protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy. J Transl Med 8:126-5876-8-126
-
(2010)
J Transl Med
, vol.8
-
-
Teng, K.Y.1
Qiu, M.Z.2
Li, Z.H.3
Luo, H.Y.4
Zeng, Z.L.5
Luo, R.Z.6
Zhang, H.Z.7
Wang, Z.Q.8
Li, Y.H.9
Xu, R.H.10
-
51
-
-
2442419814
-
Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines
-
15095299 1:CAS:528:DC%2BD2cXktFeku78%3D
-
Welsh C, Day R, McGurk C, Masters JR, Wood RD, Koberle B (2004) Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines. Int J Cancer 110:352-361
-
(2004)
Int J Cancer
, vol.110
, pp. 352-361
-
-
Welsh, C.1
Day, R.2
McGurk, C.3
Masters, J.R.4
Wood, R.D.5
Koberle, B.6
-
52
-
-
0037444279
-
Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
-
12649192 1:CAS:528:DC%2BD3sXit1Sgtbs%3D
-
Selvakumaran M, Pisarcik DA, Bao R, Yeung AT, Hamilton TC (2003) Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res 63:1311-1316
-
(2003)
Cancer Res
, vol.63
, pp. 1311-1316
-
-
Selvakumaran, M.1
Pisarcik, D.A.2
Bao, R.3
Yeung, A.T.4
Hamilton, T.C.5
-
53
-
-
33748435058
-
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
-
16957145 1:CAS:528:DC%2BD28XpsFKmtLw%3D
-
Olaussen KA, Dunant A, Fouret P, Brambilla E, Andre F, Haddad V, Taranchon E, Filipits M, Pirker R, Popper HH, Stahel R, Sabatier L, Pignon JP, Tursz T, Le Chevalier T, Soria JC, Bio Investigators IALT (2006) DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 355:983-991
-
(2006)
N Engl J Med
, vol.355
, pp. 983-991
-
-
Olaussen, K.A.1
Dunant, A.2
Fouret, P.3
Brambilla, E.4
Andre, F.5
Haddad, V.6
Taranchon, E.7
Filipits, M.8
Pirker, R.9
Popper, H.H.10
Stahel, R.11
Sabatier, L.12
Pignon, J.P.13
Tursz, T.14
Le Chevalier, T.15
Soria, J.C.16
-
54
-
-
34447573875
-
Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: A phase III trial in non-small-cell lung cancer
-
17602080 1:CAS:528:DC%2BD2sXosValtLk%3D
-
Cobo M, Isla D, Massuti B, Montes A, Sanchez JM, Provencio M, Vinolas N, Paz-Ares L, Lopez-Vivanco G, Munoz MA, Felip E, Alberola V, Camps C, Domine M, Sanchez JJ, Sanchez-Ronco M, Danenberg K, Taron M, Gandara D, Rosell R (2007) Customizing cisplatin based on quantitative excision repair cross-complementing 1 mRNA expression: a phase III trial in non-small-cell lung cancer. J Clin Oncol 25:2747-2754
-
(2007)
J Clin Oncol
, vol.25
, pp. 2747-2754
-
-
Cobo, M.1
Isla, D.2
Massuti, B.3
Montes, A.4
Sanchez, J.M.5
Provencio, M.6
Vinolas, N.7
Paz-Ares, L.8
Lopez-Vivanco, G.9
Munoz, M.A.10
Felip, E.11
Alberola, V.12
Camps, C.13
Domine, M.14
Sanchez, J.J.15
Sanchez-Ronco, M.16
Danenberg, K.17
Taron, M.18
Gandara, D.19
Rosell, R.20
more..
-
55
-
-
33847681504
-
Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy
-
Spanish Oncology Genitourinary Group 17229776 1:STN:280:DC%2BD2s7hsFKqtg%3D%3D
-
Bellmunt J, Paz-Ares L, Cuello M, Cecere FL, Albiol S, Guillem V, Gallardo E, Carles J, Mendez P, de la Cruz JJ, Taron M, Rosell R, Baselga J, Spanish Oncology Genitourinary Group (2007) Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy. Ann Oncol 18:522-528
-
(2007)
Ann Oncol
, vol.18
, pp. 522-528
-
-
Bellmunt, J.1
Paz-Ares, L.2
Cuello, M.3
Cecere, F.L.4
Albiol, S.5
Guillem, V.6
Gallardo, E.7
Carles, J.8
Mendez, P.9
De La Cruz, J.J.10
Taron, M.11
Rosell, R.12
Baselga, J.13
-
56
-
-
46349110628
-
ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation
-
18594541 1:CAS:528:DC%2BD1cXnvFeqsLY%3D 2453006
-
Jun HJ, Ahn MJ, Kim HS, Yi SY, Han J, Lee SK, Ahn YC, Jeong HS, Son YI, Baek JH, Park K (2008) ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation. Br J Cancer 99:167-172
-
(2008)
Br J Cancer
, vol.99
, pp. 167-172
-
-
Jun, H.J.1
Ahn, M.J.2
Kim, H.S.3
Yi, S.Y.4
Han, J.5
Lee, S.K.6
Ahn, Y.C.7
Jeong, H.S.8
Son, Y.I.9
Baek, J.H.10
Park, K.11
-
57
-
-
48249135539
-
Patients with ERCC1-negative locally advanced esophageal cancers may benefit from preoperative chemoradiotherapy
-
18594004 1:CAS:528:DC%2BD1cXnvFyksrc%3D
-
Kim MK, Cho KJ, Kwon GY, Park SI, Kim YH, Kim JH, Song HY, Shin JH, Jung HY, Lee GH, Choi KD, Kim SB (2008) Patients with ERCC1-negative locally advanced esophageal cancers may benefit from preoperative chemoradiotherapy. Clin Cancer Res 14:4225-4231
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4225-4231
-
-
Kim, M.K.1
Cho, K.J.2
Kwon, G.Y.3
Park, S.I.4
Kim, Y.H.5
Kim, J.H.6
Song, H.Y.7
Shin, J.H.8
Jung, H.Y.9
Lee, G.H.10
Choi, K.D.11
Kim, S.B.12
-
58
-
-
80052469770
-
A review of excision repair cross-complementation group 1 in colorectal cancer
-
21855036 1:CAS:528:DC%2BC3MXhtlKju7rJ
-
Bohanes P, Labonte MJ, Lenz HJ (2011) A review of excision repair cross-complementation group 1 in colorectal cancer. Clin Colorectal Cancer 10:157-164
-
(2011)
Clin Colorectal Cancer
, vol.10
, pp. 157-164
-
-
Bohanes, P.1
Labonte, M.J.2
Lenz, H.J.3
-
59
-
-
84876420292
-
ERCC1, defective mismatch repair status as predictive biomarkers of survival for stage III colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy
-
23481186 1:CAS:528:DC%2BC3sXlsVeqtrg%3D 3619275
-
Li P, Fang YJ, Li F, Ou QJ, Chen G, Ma G (2013) ERCC1, defective mismatch repair status as predictive biomarkers of survival for stage III colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy. Br J Cancer 108:1238-1244
-
(2013)
Br J Cancer
, vol.108
, pp. 1238-1244
-
-
Li, P.1
Fang, Y.J.2
Li, F.3
Ou, Q.J.4
Chen, G.5
Ma, G.6
-
60
-
-
79952728697
-
ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: A systemic review and meta-analysis
-
21278243 1:CAS:528:DC%2BC3MXjtFChtL8%3D 3060288
-
Yin M, Yan J, Martinez-Balibrea E, Graziano F, Lenz HJ, Kim HJ, Robert J, Im SA, Wang WS, Etienne-Grimaldi MC, Wei Q (2011) ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis. Clin Cancer Res 17:1632-1640
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1632-1640
-
-
Yin, M.1
Yan, J.2
Martinez-Balibrea, E.3
Graziano, F.4
Lenz, H.J.5
Kim, H.J.6
Robert, J.7
Im, S.A.8
Wang, W.S.9
Etienne-Grimaldi, M.C.10
Wei, Q.11
-
61
-
-
84866173015
-
Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexed-carboplatin
-
22889494
-
Tiseo M, Giovannetti E, Tibaldi C, Camerini A, Di Costanzo F, Barbieri F, Burgers JA, Vincent A, Peters GJ, Smit EF, Ardizzoni A (2012) Pharmacogenetic study of patients with advanced non-small cell lung cancer (NSCLC) treated with second-line pemetrexed or pemetrexed-carboplatin. Lung Cancer 78:92-99
-
(2012)
Lung Cancer
, vol.78
, pp. 92-99
-
-
Tiseo, M.1
Giovannetti, E.2
Tibaldi, C.3
Camerini, A.4
Di Costanzo, F.5
Barbieri, F.6
Burgers, J.A.7
Vincent, A.8
Peters, G.J.9
Smit, E.F.10
Ardizzoni, A.11
-
62
-
-
84878865076
-
Prognostic factors in gemcitabine-cisplatin polychemotherapy regimens in pancreatic cancer: XPD-Lys751Gln polymorphism strikes back
-
23390054 1:CAS:528:DC%2BC3sXjtlartL0%3D
-
Avan A, Pacetti P, Reni M, Milella M, Vasile E, Mambrini A, Vaccaro V, Caponi S, Cereda S, Peters GJ, Cantore M, Giovannetti E (2013) Prognostic factors in gemcitabine-cisplatin polychemotherapy regimens in pancreatic cancer: XPD-Lys751Gln polymorphism strikes back. Int J Cancer 133:1016-1022
-
(2013)
Int J Cancer
, vol.133
, pp. 1016-1022
-
-
Avan, A.1
Pacetti, P.2
Reni, M.3
Milella, M.4
Vasile, E.5
Mambrini, A.6
Vaccaro, V.7
Caponi, S.8
Cereda, S.9
Peters, G.J.10
Cantore, M.11
Giovannetti, E.12
-
63
-
-
8944230189
-
Loss of DNA mismatch repair in acquired resistance to cisplatin
-
8674066 1:CAS:528:DyaK28XjvFCkt7c%3D
-
Aebi S, Kurdi-Haidar B, Gordon R, Cenni B, Zheng H, Fink D, Christen RD, Boland CR, Koi M, Fishel R, Howell SB (1996) Loss of DNA mismatch repair in acquired resistance to cisplatin. Cancer Res 56:3087-3090
-
(1996)
Cancer Res
, vol.56
, pp. 3087-3090
-
-
Aebi, S.1
Kurdi-Haidar, B.2
Gordon, R.3
Cenni, B.4
Zheng, H.5
Fink, D.6
Christen, R.D.7
Boland, C.R.8
Koi, M.9
Fishel, R.10
Howell, S.B.11
-
64
-
-
0030741503
-
HMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
-
9233776 1:CAS:528:DyaK2sXkslygsbo%3D
-
Brown R, Hirst GL, Gallagher WM, McIlwrath AJ, Margison GP, van der Zee AG, Anthoney DA (1997) hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene 15:45-52
-
(1997)
Oncogene
, vol.15
, pp. 45-52
-
-
Brown, R.1
Hirst, G.L.2
Gallagher, W.M.3
McIlwrath, A.J.4
Margison, G.P.5
Van Der Zee, A.G.6
Anthoney, D.A.7
-
65
-
-
77954748953
-
Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer
-
20498393 1:CAS:528:DC%2BC3cXhtVajurzE 2903323
-
Sargent DJ, Marsoni S, Monges G, Thibodeau SN, Labianca R, Hamilton SR, French AJ, Kabat B, Foster NR, Torri V, Ribic C, Grothey A, Moore M, Zaniboni A, Seitz JF, Sinicrope F, Gallinger S (2010) Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 28:3219-3226
-
(2010)
J Clin Oncol
, vol.28
, pp. 3219-3226
-
-
Sargent, D.J.1
Marsoni, S.2
Monges, G.3
Thibodeau, S.N.4
Labianca, R.5
Hamilton, S.R.6
French, A.J.7
Kabat, B.8
Foster, N.R.9
Torri, V.10
Ribic, C.11
Grothey, A.12
Moore, M.13
Zaniboni, A.14
Seitz, J.F.15
Sinicrope, F.16
Gallinger, S.17
-
66
-
-
82555173112
-
Defective mismatch repair status as a prognostic biomarker of disease-free survival in stage III colon cancer patients treated with adjuvant FOLFOX chemotherapy
-
21998335 1:CAS:528:DC%2BC3MXhsFCmtrfK
-
Zaanan A, Flejou JF, Emile JF, Des GG, Cuilliere-Dartigues P, Malka D, Lecaille C, Validire P, Louvet C, Rougier P, de Gramont A, Bonnetain F, Praz F, Taieb J (2011) Defective mismatch repair status as a prognostic biomarker of disease-free survival in stage III colon cancer patients treated with adjuvant FOLFOX chemotherapy. Clin Cancer Res 17:7470-7478
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7470-7478
-
-
Zaanan, A.1
Flejou, J.F.2
Emile, J.F.3
Des, G.G.4
Cuilliere-Dartigues, P.5
Malka, D.6
Lecaille, C.7
Validire, P.8
Louvet, C.9
Rougier, P.10
De Gramont, A.11
Bonnetain, F.12
Praz, F.13
Taieb, J.14
-
67
-
-
84865688579
-
Cancer treatment according to BRCA1 and BRCA2 mutations
-
22825375 1:CAS:528:DC%2BC38Xht1Kjs7zM
-
Maxwell KN, Domchek SM (2012) Cancer treatment according to BRCA1 and BRCA2 mutations. Nat Rev Clin Oncol 9:520-528
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 520-528
-
-
Maxwell, K.N.1
Domchek, S.M.2
-
68
-
-
80053950209
-
Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer
-
21990299 1:CAS:528:DC%2BC3MXhtlelsbvI 4159096
-
Yang D, Khan S, Sun Y, Hess K, Shmulevich I, Sood AK, Zhang W (2011) Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer. JAMA 306:1557-1565
-
(2011)
JAMA
, vol.306
, pp. 1557-1565
-
-
Yang, D.1
Khan, S.2
Sun, Y.3
Hess, K.4
Shmulevich, I.5
Sood, A.K.6
Zhang, W.7
-
69
-
-
84908365902
-
Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers
-
25072261 1:CAS:528:DC%2BC2cXht1GksL3N 4453851
-
Golan T, Kanji ZS, Epelbaum R, Devaud N, Dagan E, Holter S, Aderka D, Paluch-Shimon S, Kaufman B, Gershoni-Baruch R, Hedley D, Moore MJ, Friedman E, Gallinger S (2014) Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers. Br J Cancer 111:1132-1138
-
(2014)
Br J Cancer
, vol.111
, pp. 1132-1138
-
-
Golan, T.1
Kanji, Z.S.2
Epelbaum, R.3
Devaud, N.4
Dagan, E.5
Holter, S.6
Aderka, D.7
Paluch-Shimon, S.8
Kaufman, B.9
Gershoni-Baruch, R.10
Hedley, D.11
Moore, M.J.12
Friedman, E.13
Gallinger, S.14
-
70
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
18264087 1:CAS:528:DC%2BD1cXisFWjt74%3D 2577037
-
Sakai W, Swisher EM, Karlan BY, Agarwal MK, Higgins J, Friedman C, Villegas E, Jacquemont C, Farrugia DJ, Couch FJ, Urban N, Taniguchi T (2008) Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 451:1116-1120
-
(2008)
Nature
, vol.451
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
Agarwal, M.K.4
Higgins, J.5
Friedman, C.6
Villegas, E.7
Jacquemont, C.8
Farrugia, D.J.9
Couch, F.J.10
Urban, N.11
Taniguchi, T.12
-
71
-
-
42349096328
-
Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
-
18413725 1:CAS:528:DC%2BD1cXks1Git7c%3D 2674369
-
Swisher EM, Sakai W, Karlan BY, Wurz K, Urban N, Taniguchi T (2008) Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res 68:2581-2586
-
(2008)
Cancer Res
, vol.68
, pp. 2581-2586
-
-
Swisher, E.M.1
Sakai, W.2
Karlan, B.Y.3
Wurz, K.4
Urban, N.5
Taniguchi, T.6
-
72
-
-
37549007196
-
Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab
-
18094427 1:CAS:528:DC%2BD2sXhsVCktr3L
-
Prewett M, Deevi DS, Bassi R, Fan F, Ellis LM, Hicklin DJ, Tonra JR (2007) Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab. Clin Cancer Res 13:7432-7440
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7432-7440
-
-
Prewett, M.1
Deevi, D.S.2
Bassi, R.3
Fan, F.4
Ellis, L.M.5
Hicklin, D.J.6
Tonra, J.R.7
-
73
-
-
0034769605
-
MAPK dependence of DNA damage repair: Ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion
-
11682011 1:CAS:528:DC%2BD3MXnvFSmurc%3D
-
Yacoub A, Park JS, Qiao L, Dent P, Hagan MP (2001) MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion. Int J Radiat Biol 77:1067-1078
-
(2001)
Int J Radiat Biol
, vol.77
, pp. 1067-1078
-
-
Yacoub, A.1
Park, J.S.2
Qiao, L.3
Dent, P.4
Hagan, M.P.5
-
74
-
-
78349254271
-
The insulin-like growth factor i receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models
-
20943761 1:CAS:528:DC%2BC3cXhsVWmsbjN 3119523
-
Flanigan SA, Pitts TM, Eckhardt SG, Tentler JJ, Tan AC, Thorburn A, Leong S (2010) The insulin-like growth factor I receptor/insulin receptor tyrosine kinase inhibitor PQIP exhibits enhanced antitumor effects in combination with chemotherapy against colorectal cancer models. Clin Cancer Res 16:5436-5446
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5436-5446
-
-
Flanigan, S.A.1
Pitts, T.M.2
Eckhardt, S.G.3
Tentler, J.J.4
Tan, A.C.5
Thorburn, A.6
Leong, S.7
-
75
-
-
62449205665
-
Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
-
19244128 1:CAS:528:DC%2BD1MXisFSrtb4%3D 3198868
-
Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren G, Samuel S, Kim MP, Lim SJ, Ellis LM (2009) Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 69:1951-1957
-
(2009)
Cancer Res
, vol.69
, pp. 1951-1957
-
-
Dallas, N.A.1
Xia, L.2
Fan, F.3
Gray, M.J.4
Gaur, P.5
Van Buren, I.I.G.6
Samuel, S.7
Kim, M.P.8
Lim, S.J.9
Ellis, L.M.10
-
76
-
-
36849018017
-
Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R
-
17918158 1:CAS:528:DC%2BD2sXhsVOnsrrK
-
Patel BB, Sengupta R, Qazi S, Vachhani H, Yu Y, Rishi AK, Majumdar AP (2008) Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int J Cancer 122:267-273
-
(2008)
Int J Cancer
, vol.122
, pp. 267-273
-
-
Patel, B.B.1
Sengupta, R.2
Qazi, S.3
Vachhani, H.4
Yu, Y.5
Rishi, A.K.6
Majumdar, A.P.7
-
77
-
-
81955167415
-
Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells
-
22045189 1:CAS:528:DC%2BC3MXhsFWqs7bN 3242606
-
Bose D, Zimmerman LJ, Pierobon M, Petricoin E, Tozzi F, Parikh A, Fan F, Dallas N, Xia L, Gaur P, Samuel S, Liebler DC, Ellis LM (2011) Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells. Br J Cancer 105:1759-1767
-
(2011)
Br J Cancer
, vol.105
, pp. 1759-1767
-
-
Bose, D.1
Zimmerman, L.J.2
Pierobon, M.3
Petricoin, E.4
Tozzi, F.5
Parikh, A.6
Fan, F.7
Dallas, N.8
Xia, L.9
Gaur, P.10
Samuel, S.11
Liebler, D.C.12
Ellis, L.M.13
-
78
-
-
84892174197
-
Functional and clinical implications of autocrine VEGF signaling in colorectal cancer
-
Larsen AK, de Gramont A, Poindessous V, Bouygues A, Ayadi M, Mésange P (2013) Functional and clinical implications of autocrine VEGF signaling in colorectal cancer. Curr Colorectal Cancer Rep 9:270-277
-
(2013)
Curr Colorectal Cancer Rep
, vol.9
, pp. 270-277
-
-
Larsen, A.K.1
De Gramont, A.2
Poindessous, V.3
Bouygues, A.4
Ayadi, M.5
Mésange, P.6
-
79
-
-
33847327128
-
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines
-
16857785 1:CAS:528:DC%2BD28XntFSmsrc%3D
-
Yang AD, Fan F, Camp ER, van Buren G, Liu W, Somcio R, Gray MJ, Cheng H, Hoff PM, Ellis LM (2006) Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res 12:4147-4153
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4147-4153
-
-
Yang, A.D.1
Fan, F.2
Camp, E.R.3
Van Buren, G.4
Liu, W.5
Somcio, R.6
Gray, M.J.7
Cheng, H.8
Hoff, P.M.9
Ellis, L.M.10
-
80
-
-
0141838134
-
Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids
-
14521839 1:CAS:528:DC%2BD3sXnvVOmtb0%3D
-
Bates RC, Goldsmith JD, Bachelder RE, Brown C, Shibuya M, Oettgen P, Mercurio AM (2003) Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids. Curr Biol 13:1721-1727
-
(2003)
Curr Biol
, vol.13
, pp. 1721-1727
-
-
Bates, R.C.1
Goldsmith, J.D.2
Bachelder, R.E.3
Brown, C.4
Shibuya, M.5
Oettgen, P.6
Mercurio, A.M.7
-
81
-
-
77955037795
-
Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters
-
20551056 1:CAS:528:DC%2BC3cXovVanu7g%3D 2906706
-
Morrow CJ, Ghattas M, Smith C, Bonisch H, Bryce RA, Hickinson DM, Green TP, Dive C (2010) Src family kinase inhibitor Saracatinib (AZD0530) impairs oxaliplatin uptake in colorectal cancer cells and blocks organic cation transporters. Cancer Res 70:5931-5941
-
(2010)
Cancer Res
, vol.70
, pp. 5931-5941
-
-
Morrow, C.J.1
Ghattas, M.2
Smith, C.3
Bonisch, H.4
Bryce, R.A.5
Hickinson, D.M.6
Green, T.P.7
Dive, C.8
-
82
-
-
84876706092
-
Modulation of sensitivity to antitumor agents by targeting the MAPK survival pathway
-
22973957 1:CAS:528:DC%2BC3sXktF2lt7Y%3D
-
Cossa G, Gatti L, Cassinelli G, Lanzi C, Zaffaroni N, Perego P (2013) Modulation of sensitivity to antitumor agents by targeting the MAPK survival pathway. Curr Pharm Des 19:883-894
-
(2013)
Curr Pharm des
, vol.19
, pp. 883-894
-
-
Cossa, G.1
Gatti, L.2
Cassinelli, G.3
Lanzi, C.4
Zaffaroni, N.5
Perego, P.6
-
83
-
-
41649102402
-
Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds
-
18347153 1:CAS:528:DC%2BD1cXjtlWgsrY%3D
-
Benedetti V, Perego P, Luca Beretta G, Corna E, Tinelli S, Righetti SC, Leone R, Apostoli P, Lanzi C, Zunino F (2008) Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds. Mol Cancer Ther 7:679-687
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 679-687
-
-
Benedetti, V.1
Perego, P.2
Luca Beretta, G.3
Corna, E.4
Tinelli, S.5
Righetti, S.C.6
Leone, R.7
Apostoli, P.8
Lanzi, C.9
Zunino, F.10
-
84
-
-
84898457102
-
Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells
-
24576622 1:CAS:528:DC%2BC2cXkt1Wisbc%3D
-
Cossa G, Lanzi C, Cassinelli G, Carenini N, Arrighetti N, Gatti L, Corna E, Zunino F, Zaffaroni N, Perego P (2014) Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells. Cancer Lett 347:212-224
-
(2014)
Cancer Lett
, vol.347
, pp. 212-224
-
-
Cossa, G.1
Lanzi, C.2
Cassinelli, G.3
Carenini, N.4
Arrighetti, N.5
Gatti, L.6
Corna, E.7
Zunino, F.8
Zaffaroni, N.9
Perego, P.10
-
85
-
-
77950858034
-
Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa
-
20354524 2856010
-
de Bruijn MT, Raats DA, Hoogwater FJ, van Houdt WJ, Cameron K, Medema JP, Borel Rinkes IH, Kranenburg O (2010) Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br J Cancer 102:1254-1264
-
(2010)
Br J Cancer
, vol.102
, pp. 1254-1264
-
-
De Bruijn, M.T.1
Raats, D.A.2
Hoogwater, F.J.3
Van Houdt, W.J.4
Cameron, K.5
Medema, J.P.6
Borel Rinkes, I.H.7
Kranenburg, O.8
-
86
-
-
34250723431
-
P53 dependent and independent sensitivity to oxaliplatin of colon cancer cells
-
17559811 1:CAS:528:DC%2BD2sXntFamur8%3D
-
Toscano F, Parmentier B, Fajoui ZE, Estornes Y, Chayvialle JA, Saurin JC, Abello J (2007) P53 dependent and independent sensitivity to oxaliplatin of colon cancer cells. Biochem Pharmacol 74:392-406
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 392-406
-
-
Toscano, F.1
Parmentier, B.2
Fajoui, Z.E.3
Estornes, Y.4
Chayvialle, J.A.5
Saurin, J.C.6
Abello, J.7
-
87
-
-
57349084704
-
Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis
-
18780829 1:CAS:528:DC%2BD1cXhsVCjtLvP
-
Wilson C, Purcell C, Seaton A, Oladipo O, Maxwell PJ, O'Sullivan JM, Wilson RH, Johnston PG, Waugh DJ (2008) Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis. J Pharmacol Exp Ther 327:746-759
-
(2008)
J Pharmacol Exp Ther
, vol.327
, pp. 746-759
-
-
Wilson, C.1
Purcell, C.2
Seaton, A.3
Oladipo, O.4
Maxwell, P.J.5
O'Sullivan, J.M.6
Wilson, R.H.7
Johnston, P.G.8
Waugh, D.J.9
-
88
-
-
73349114941
-
KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: Results from the MRC FOCUS trial
-
19884549 1:CAS:528:DC%2BC3cXhtVWisL4%3D
-
Richman SD, Seymour MT, Chambers P, Elliott F, Daly CL, Meade AM, Taylor G, Barrett JH, Quirke P (2009) KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. J Clin Oncol 27:5931-5937
-
(2009)
J Clin Oncol
, vol.27
, pp. 5931-5937
-
-
Richman, S.D.1
Seymour, M.T.2
Chambers, P.3
Elliott, F.4
Daly, C.L.5
Meade, A.M.6
Taylor, G.7
Barrett, J.H.8
Quirke, P.9
-
89
-
-
68149165771
-
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
-
19603024 1:CAS:528:DC%2BD1MXpsVKmsr4%3D 2720232
-
Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA (2009) Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer 101:465-472
-
(2009)
Br J Cancer
, vol.101
, pp. 465-472
-
-
Souglakos, J.1
Philips, J.2
Wang, R.3
Marwah, S.4
Silver, M.5
Tzardi, M.6
Silver, J.7
Ogino, S.8
Hooshmand, S.9
Kwak, E.10
Freed, E.11
Meyerhardt, J.A.12
Saridaki, Z.13
Georgoulias, V.14
Finkelstein, D.15
Fuchs, C.S.16
Kulke, M.H.17
Shivdasani, R.A.18
-
90
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
17979839 1:CAS:528:DC%2BD2sXhsVKgtr3L
-
Apetoh L, Ghiringhelli F, Tesniere A, Criollo A, Ortiz C, Lidereau R, Mariette C, Chaput N, Mira JP, Delaloge S, Andre F, Tursz T, Kroemer G, Zitvogel L (2007) The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev 220:47-59
-
(2007)
Immunol Rev
, vol.220
, pp. 47-59
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Criollo, A.4
Ortiz, C.5
Lidereau, R.6
Mariette, C.7
Chaput, N.8
Mira, J.P.9
Delaloge, S.10
Andre, F.11
Tursz, T.12
Kroemer, G.13
Zitvogel, L.14
-
91
-
-
84890103572
-
Molecular mechanisms of ATP secretion during immunogenic cell death
-
23852373 1:CAS:528:DC%2BC3sXhvFCqs7rN 3857631
-
Martins I, Wang Y, Michaud M, Ma Y, Sukkurwala AQ, Shen S, Kepp O, Metivier D, Galluzzi L, Perfettini JL, Zitvogel L, Kroemer G (2014) Molecular mechanisms of ATP secretion during immunogenic cell death. Cell Death Differ 21:79-91
-
(2014)
Cell Death Differ
, vol.21
, pp. 79-91
-
-
Martins, I.1
Wang, Y.2
Michaud, M.3
Ma, Y.4
Sukkurwala, A.Q.5
Shen, S.6
Kepp, O.7
Metivier, D.8
Galluzzi, L.9
Perfettini, J.L.10
Zitvogel, L.11
Kroemer, G.12
-
92
-
-
84906489918
-
Trial watch: Immunostimulatory cytokines in cancer therapy
-
25083328 4091551
-
Vacchelli E, Aranda F, Obrist F, Eggermont A, Galon J, Cremer I, Zitvogel L, Kroemer G, Galluzzi L (2014) Trial watch: immunostimulatory cytokines in cancer therapy. Oncoimmunology 3:e29030
-
(2014)
Oncoimmunology
, vol.3
, pp. e29030
-
-
Vacchelli, E.1
Aranda, F.2
Obrist, F.3
Eggermont, A.4
Galon, J.5
Cremer, I.6
Zitvogel, L.7
Kroemer, G.8
Galluzzi, L.9
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