-
1
-
-
0038668000
-
Escaping cell death: Survival proteins in cancer
-
Jaattela, M. (1999). Escaping cell death: survival proteins in cancer. Exp. Cell Res. 248, 30-43.
-
(1999)
Exp. Cell Res.
, vol.248
, pp. 30-43
-
-
Jaattela, M.1
-
2
-
-
0037572319
-
Tumor necrosis factor-α stimulates the epithelial to mesenchymal transition of human colonic organoids
-
Bates, R.C., and Mercurio, A.M. (2003). Tumor necrosis factor-α stimulates the epithelial to mesenchymal transition of human colonic organoids. Mol. Biol. Cell 14, 1790-1800.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 1790-1800
-
-
Bates, R.C.1
Mercurio, A.M.2
-
3
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft, M., Pili, J., Rudaz, C., Schwarz, H., Beug, H., and Reichmann, E. (1996). TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10, 2462-2477.
-
(1996)
Genes Dev.
, vol.10
, pp. 2462-2477
-
-
Oft, M.1
Pili, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
4
-
-
0032547895
-
TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
-
Oft, M., Heider, K.H., and Berg, H. (1998). TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis. Curr. Biol. 8, 1243-1252.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1243-1252
-
-
Oft, M.1
Heider, K.H.2
Berg, H.3
-
5
-
-
0035185853
-
Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a Rho-A-dependent mechanism
-
Bhowmick, N.A., Ghiassi, M., Bakin, A., Aakre, M., Lundquist, C.A., Engel, M.E., Artega, C.L., and Moses, H.L. (2001). Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a Rho-A-dependent mechanism. Mol. Biol. Cell 12, 27-36.
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 27-36
-
-
Bhowmick, N.A.1
Ghiassi, M.2
Bakin, A.3
Aakre, M.4
Lundquist, C.A.5
Engel, M.E.6
Artega, C.L.7
Moses, H.L.8
-
6
-
-
0029553183
-
An overview of the epithelio-mesenchymal transformation
-
Hay, E.D. (1995). An overview of the epithelio-mesenchymal transformation. Acta Anat. 154, 8-20.
-
(1995)
Acta Anat.
, vol.154
, pp. 8-20
-
-
Hay, E.D.1
-
7
-
-
0034798707
-
Leaving the neighborhood: Molecular mechanisms involved during epithelial-mesenchymal transition
-
Savagner, P. (2001). Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. Bioessays 23, 912-923.
-
(2001)
Bioessays
, vol.23
, pp. 912-923
-
-
Savagner, P.1
-
8
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery, J.P. (2002). Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2, 442-454.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
9
-
-
0023265494
-
A new colon carcinoma cell line (LIM 1863) that grows as organoids with spontaneous differentiation into crypt-like structures in vitro
-
Whitehead, R.H., Jones, J.K., Gabriel, A., and Lukies, R.E. (1987). A new colon carcinoma cell line (LIM 1863) that grows as organoids with spontaneous differentiation into crypt-like structures in vitro. Cancer Res. 47, 2683-2689.
-
(1987)
Cancer Res.
, vol.47
, pp. 2683-2689
-
-
Whitehead, R.H.1
Jones, J.K.2
Gabriel, A.3
Lukies, R.E.4
-
10
-
-
0028258533
-
Apoptosis induced by inhibition of intercellular contact
-
Bates, R.C., Buret, A., van Helden, D.F., Horton, M.A., and Burns, G.F. (1994). Apoptosis induced by inhibition of intercellular contact. J. Cell Biol. 125, 403-415.
-
(1994)
J. Cell Biol.
, vol.125
, pp. 403-415
-
-
Bates, R.C.1
Buret, A.2
Van Helden, D.F.3
Horton, M.A.4
Burns, G.F.5
-
11
-
-
0027997863
-
Different signal transduction properties of KDR and Flt-1, two receptors for vascular endothelial growth factor
-
Waltenberger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M., and Heldin, C.H. (1994). Different signal transduction properties of KDR and Flt-1, two receptors for vascular endothelial growth factor. J. Biol. Chem. 269, 26988-26995.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26988-26995
-
-
Waltenberger, J.1
Claesson-Welsh, L.2
Siegbahn, A.3
Shibuya, M.4
Heldin, C.H.5
-
12
-
-
0032053767
-
Signaling angiogenesis and lymphangiogenesis
-
Korpelainen, E.I., and Alitalo, K. (1998). Signaling angiogenesis and lymphangiogenesis. Curr. Opin. Cell Biol. 10, 159-164.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 159-164
-
-
Korpelainen, E.I.1
Alitalo, K.2
-
13
-
-
0035114105
-
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis
-
Hiratsuka, S., Maru, Y., Okada, A., Seiki, M., Noda, T., and Shibuya, M. (2001). Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res. 61, 1207-1213.
-
(2001)
Cancer Res.
, vol.61
, pp. 1207-1213
-
-
Hiratsuka, S.1
Maru, Y.2
Okada, A.3
Seiki, M.4
Noda, T.5
Shibuya, M.6
-
14
-
-
0028134936
-
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
-
Park, J.E., Chen, H.H., Winer, J., Houck, K.A., and Ferrara, N. (1994). Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J. Biol. Chem. 269, 25646-25654.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25646-25654
-
-
Park, J.E.1
Chen, H.H.2
Winer, J.3
Houck, K.A.4
Ferrara, N.5
-
15
-
-
0034323062
-
De novo expression of vascular endothelial growth factor in human pancreatic cancer: Evidence for an autocrine mitogenic loop
-
von Marschall, Z., Cramer, T., Hocker, M., Burde, R., Plath, T., Schirner, M., Heindrich, R., Breier, G., Riecken, E.O., Wiedenmann, B., et al. (2000). De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop. Gastroenterology 119, 1358-1372.
-
(2000)
Gastroenterology
, vol.119
, pp. 1358-1372
-
-
Von Marschall, Z.1
Cramer, T.2
Hocker, M.3
Burde, R.4
Plath, T.5
Schirner, M.6
Heindrich, R.7
Breier, G.8
Riecken, E.O.9
Wiedenmann, B.10
-
16
-
-
0034891532
-
Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype
-
Soker, S., Kaefer, M., Johnson, M., Klagsbrun, M., Atala, A., and Freeman, M.R. (2001). Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype. Am. J. Pathol. 159, 651-659.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 651-659
-
-
Soker, S.1
Kaefer, M.2
Johnson, M.3
Klagsbrun, M.4
Atala, A.5
Freeman, M.R.6
-
17
-
-
0036219606
-
Upregulation of vascular endothelial growth factor receptors is associated with advanced neuroblastoma
-
Fakhari, M., Pullirsch, D., Paya, K., Abraham, D., Hofbauer, R., and Aharinejad, S. (2002). Upregulation of vascular endothelial growth factor receptors is associated with advanced neuroblastoma. J. Pediatr. Surg. 37, 582-587.
-
(2002)
J. Pediatr. Surg.
, vol.37
, pp. 582-587
-
-
Fakhari, M.1
Pullirsch, D.2
Paya, K.3
Abraham, D.4
Hofbauer, R.5
Aharinejad, S.6
-
18
-
-
0029807470
-
A cAMP response element and an Ets motif are involved in the transcriptional regulation of the flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene
-
Wakiya, K., Begue, A., Stehelin, D., and Shibuya, M. (1996). A cAMP response element and an Ets motif are involved in the transcriptional regulation of the flt-1 tyrosine kinase (vascular endothelial growth factor receptor 1) gene. J. Biol. Chem. 271, 30823-30828.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30823-30828
-
-
Wakiya, K.1
Begue, A.2
Stehelin, D.3
Shibuya, M.4
-
19
-
-
0033612363
-
Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene
-
Dube, A., Akbarali, Y., Sato, T.N., Libermann, T.A., and Oettgen, P. (1999). Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene. Circ. Res, 84, 1177-1185.
-
(1999)
Circ. Res
, vol.84
, pp. 1177-1185
-
-
Dube, A.1
Akbarali, Y.2
Sato, T.N.3
Libermann, T.A.4
Oettgen, P.5
-
20
-
-
0034665166
-
Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice
-
Brekken, R.A., Overholser, J.P., Stastny, V.A., Walteneberger, J., Minna, J.D., and Thorpe, P.E. (2000). Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice. Cancer Res, 60, 5117-5124.
-
(2000)
Cancer Res
, vol.60
, pp. 5117-5124
-
-
Brekken, R.A.1
Overholser, J.P.2
Stastny, V.A.3
Walteneberger, J.4
Minna, J.D.5
Thorpe, P.E.6
-
21
-
-
0035254646
-
Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans
-
Sawano, A., Iwai, S., Sakurai, Y., Ito, M., Shitara, K., Nakahata, T., and Shibuya, M. (2001). Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. Blood 97, 785-791.
-
(2001)
Blood
, vol.97
, pp. 785-791
-
-
Sawano, A.1
Iwai, S.2
Sakurai, Y.3
Ito, M.4
Shitara, K.5
Nakahata, T.6
Shibuya, M.7
-
22
-
-
0035836697
-
Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer
-
Kuo, C.J., Farnebo, F., Yu, E.Y., Christofferson, R., Swearingen, R.A., Carter, R., von Recum, H.A., Yuan, J., Kamihara, J., Flynn, E., et al. (2001). Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc. Natl. Acad. Sci. USA 98, 4606-4610.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4606-4610
-
-
Kuo, C.J.1
Farnebo, F.2
Yu, E.Y.3
Christofferson, R.4
Swearingen, R.A.5
Carter, R.6
Von Recum, H.A.7
Yuan, J.8
Kamihara, J.9
Flynn, E.10
-
23
-
-
0021016610
-
Intercellular karyotypic similarity in near-diploid cell lines of human tumor origins
-
Chen, T.R., Hay, R.J., and Macy, M.L. (1983). Intercellular karyotypic similarity in near-diploid cell lines of human tumor origins. Cancer Genet. Cytogenet. 10, 351-362.
-
(1983)
Cancer Genet. Cytogenet.
, vol.10
, pp. 351-362
-
-
Chen, T.R.1
Hay, R.J.2
Macy, M.L.3
-
24
-
-
0035068834
-
Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma
-
Strizzi, L., Catalano, A., Vianale, G., Orecchia, S., Casalini, A., Tassi, G., Puntoni, R., Mutti, L., and Procopio, A. (2001). Vascular endothelial growth factor is an autocrine growth factor in human malignant mesothelioma. J. Pathol. 193, 468-475.
-
(2001)
J. Pathol.
, vol.193
, pp. 468-475
-
-
Strizzi, L.1
Catalano, A.2
Vianale, G.3
Orecchia, S.4
Casalini, A.5
Tassi, G.6
Puntoni, R.7
Mutti, L.8
Procopio, A.9
-
25
-
-
0037182861
-
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
-
Gerber, H.-P., Malik, A.K., Solar, G.P., Sherman, D., Liang, X.H., Meng, G., Hong, K., Marsters, J.C., and Ferrara, N. (2002). VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature 417, 954-958.
-
(2002)
Nature
, vol.417
, pp. 954-958
-
-
Gerber, H.-P.1
Malik, A.K.2
Solar, G.P.3
Sherman, D.4
Liang, X.H.5
Meng, G.6
Hong, K.7
Marsters, J.C.8
Ferrara, N.9
-
26
-
-
0037265805
-
Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells Molt-4
-
Broggini, M., Marchini, S.V., Galliera, E., Borsotti, P., Taraboletti, G., Erba, E., Sironi, M., Jimeno, J., Faircloth, G.T., Giavazzi, R., et al. (2003). Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells Molt-4. Leukemia 17, 52-59.
-
(2003)
Leukemia
, vol.17
, pp. 52-59
-
-
Broggini, M.1
Marchini, S.V.2
Galliera, E.3
Borsotti, P.4
Taraboletti, G.5
Erba, E.6
Sironi, M.7
Jimeno, J.8
Faircloth, G.T.9
Giavazzi, R.10
-
27
-
-
0032822591
-
Vascular endothelial growth factor-induced migration of vascular smooth muscle cells in vitro
-
Grosskreutz, C.L., Anand-Apte, B., Duplaa, C., Quinn, T.P., Terman, B.I., Zetter, B., and D'Amore, P.A. (1999). Vascular endothelial growth factor-induced migration of vascular smooth muscle cells in vitro. Microvasc. Res. 58, 128-136.
-
(1999)
Microvasc. Res.
, vol.58
, pp. 128-136
-
-
Grosskreutz, C.L.1
Anand-Apte, B.2
Duplaa, C.3
Quinn, T.P.4
Terman, B.I.5
Zetter, B.6
D'Amore, P.A.7
-
28
-
-
0034892980
-
Expression of vascular endothelial growth factor receptors in smooth muscle cells
-
Ishida, A., Murray, J., Saito, Y., Kanthou, C., Benzakour, O., Shibuya, M., and Wijelath, E.S. (2001). Expression of vascular endothelial growth factor receptors in smooth muscle cells. J. Cell. Physiol. 188, 359-368.
-
(2001)
J. Cell. Physiol.
, vol.188
, pp. 359-368
-
-
Ishida, A.1
Murray, J.2
Saito, Y.3
Kanthou, C.4
Benzakour, O.5
Shibuya, M.6
Wijelath, E.S.7
-
29
-
-
0034028399
-
Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa
-
Andre, T., Kotelevets, L., Vaillant, J.C., Coudray, A.M., Weber, L., Prevot, S., Parc, R., Gespach, C., and Chastre, E. (2000). Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa. Int. J. Cancer 86, 174-181.
-
(2000)
Int. J. Cancer
, vol.86
, pp. 174-181
-
-
Andre, T.1
Kotelevets, L.2
Vaillant, J.C.3
Coudray, A.M.4
Weber, L.5
Prevot, S.6
Parc, R.7
Gespach, C.8
Chastre, E.9
-
30
-
-
0028935608
-
Regulation by vascular enothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
-
Warren, R.S., Yuan, H., Matli, M.R., Gillett, N.A., and Ferrara, N. (1995). Regulation by vascular enothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J. Clin. Invest. 95, 1789-1797.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1789-1797
-
-
Warren, R.S.1
Yuan, H.2
Matli, M.R.3
Gillett, N.A.4
Ferrara, N.5
-
31
-
-
0034772251
-
Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma
-
Mahasreshti, P.J., Navarro, J.G., Kataram, M., Wang, M.H., Carey, D., Siegal, G.P., Barnes, M.N., Nettelbeck, D.M., Alvarez, R.D., Hemminki, A., et al. (2001). Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma. Clin. Cancer Res. 7, 2057-2066.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2057-2066
-
-
Mahasreshti, P.J.1
Navarro, J.G.2
Kataram, M.3
Wang, M.H.4
Carey, D.5
Siegal, G.P.6
Barnes, M.N.7
Nettelbeck, D.M.8
Alvarez, R.D.9
Hemminki, A.10
-
32
-
-
0036531821
-
Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer
-
Hasumi, Y., Mizukami, H., Urabe, M., Kohno, T., Takeuchi, K., Kume, A., Momoeda, M., Yoshikawa, H., Tsuruo, T., Shibuya, M., et al. (2002). Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer. Cancer Res. 62, 2019-2023.
-
(2002)
Cancer Res.
, vol.62
, pp. 2019-2023
-
-
Hasumi, Y.1
Mizukami, H.2
Urabe, M.3
Kohno, T.4
Takeuchi, K.5
Kume, A.6
Momoeda, M.7
Yoshikawa, H.8
Tsuruo, T.9
Shibuya, M.10
-
33
-
-
0036316020
-
Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor
-
Hoshida, T., Sunamura, M., Duda, D.G., Egawa, S., Miyazaki, S., Shineha, R., Hamada, H., Ohtani, H., Satomi, S., and Matsuno, S. (2002). Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor. Pancreas 25, 111-121.
-
(2002)
Pancreas
, vol.25
, pp. 111-121
-
-
Hoshida, T.1
Sunamura, M.2
Duda, D.G.3
Egawa, S.4
Miyazaki, S.5
Shineha, R.6
Hamada, H.7
Ohtani, H.8
Satomi, S.9
Matsuno, S.10
-
34
-
-
0035503609
-
sFlt-1 gene-transfected fibroblasts: A wound specific gene therapy inhibits local cancer recurrence
-
Yang, W., Arii, S., Mori, A., Furumoto, K., Nakao, T., Isobe, N., Murata, T., Onodera, H., and Imamura, M. (2001). sFlt-1 gene-transfected fibroblasts: a wound specific gene therapy inhibits local cancer recurrence. Cancer Res. 61, 7840-7845.
-
(2001)
Cancer Res.
, vol.61
, pp. 7840-7845
-
-
Yang, W.1
Arii, S.2
Mori, A.3
Furumoto, K.4
Nakao, T.5
Isobe, N.6
Murata, T.7
Onodera, H.8
Imamura, M.9
-
35
-
-
0034655246
-
Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
-
Takayama, KK., Ueno, H., Nakanishi, Y., Sakamoto, T., Inoue, K., Shimizu, K., Oohashi, H., and Hara, N. (2000). Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res. 60, 2169-2177.
-
(2000)
Cancer Res.
, vol.60
, pp. 2169-2177
-
-
Takayama, K.K.1
Ueno, H.2
Nakanishi, Y.3
Sakamoto, T.4
Inoue, K.5
Shimizu, K.6
Oohashi, H.7
Hara, N.8
-
36
-
-
0036915886
-
Therapies directed at vascular endothelial growth factor
-
Manley, P.W., Martiny-Baron, G., Schlaeppi, J.-M., and Wood, J.M. (2002). Therapies directed at vascular endothelial growth factor. Expert Opin. Investig. Drugs 11, 1715-1736.
-
(2002)
Expert Opin. Investig. Drugs
, vol.11
, pp. 1715-1736
-
-
Manley, P.W.1
Martiny-Baron, G.2
Schlaeppi, J.-M.3
Wood, J.M.4
|