-
1
-
-
0033989203
-
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
-
Giacchetti S., Perpoint B., Zidani R., Le Bail N., Faggiuolo R., Focan C., et al. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 18 (2000) 136-147
-
(2000)
J Clin Oncol
, vol.18
, pp. 136-147
-
-
Giacchetti, S.1
Perpoint, B.2
Zidani, R.3
Le Bail, N.4
Faggiuolo, R.5
Focan, C.6
-
2
-
-
0000460127
-
Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel
-
Rixe O., Ortuzar W., Alvarez M., Parker R., Reed E., Paull K., et al. Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel. Biochem Pharmacol 52 (1996) 1855-1865
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 1855-1865
-
-
Rixe, O.1
Ortuzar, W.2
Alvarez, M.3
Parker, R.4
Reed, E.5
Paull, K.6
-
3
-
-
17444422174
-
Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy
-
Kweekel D.M., Gelderblom H., and Guchelaar H.J. Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy. Cancer Treat Rev 31 (2005) 90-105
-
(2005)
Cancer Treat Rev
, vol.31
, pp. 90-105
-
-
Kweekel, D.M.1
Gelderblom, H.2
Guchelaar, H.J.3
-
4
-
-
18644383632
-
Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma
-
Gourdier I., Del Rio M., Crabbe L., Candeil L., Copois V., Ychou M., et al. Drug specific resistance to oxaliplatin is associated with apoptosis defect in a cellular model of colon carcinoma. FEBS Lett 529 (2002) 232-236
-
(2002)
FEBS Lett
, vol.529
, pp. 232-236
-
-
Gourdier, I.1
Del Rio, M.2
Crabbe, L.3
Candeil, L.4
Copois, V.5
Ychou, M.6
-
5
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz F., Hwang P.M., Torrance C., Waldman T., Zhang Y., Dillehay L., et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 104 (1999) 263-269
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
-
6
-
-
0035874884
-
Augenlicht LH. c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo
-
Arango D., Corner G.A., Wadler S., and Catalano P.J. Augenlicht LH. c-myc/p53 interaction determines sensitivity of human colon carcinoma cells to 5-fluorouracil in vitro and in vivo. Cancer Res 61 (2001) 4910-4915
-
(2001)
Cancer Res
, vol.61
, pp. 4910-4915
-
-
Arango, D.1
Corner, G.A.2
Wadler, S.3
Catalano, P.J.4
-
7
-
-
33646843583
-
DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis
-
Bhonde M.R., Hanski M.L., Budczies J., Cao M., Gillissen B., Moorthy D., et al. DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis. J Biol Chem 281 (2006) 8675-8685
-
(2006)
J Biol Chem
, vol.281
, pp. 8675-8685
-
-
Bhonde, M.R.1
Hanski, M.L.2
Budczies, J.3
Cao, M.4
Gillissen, B.5
Moorthy, D.6
-
8
-
-
0036722801
-
Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status
-
Magrini R., Bhonde M.R., Hanski M.L., Notter M., Scherubl H., Boland C.R., et al. Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status. Int J Cancer 101 (2002) 23-31
-
(2002)
Int J Cancer
, vol.101
, pp. 23-31
-
-
Magrini, R.1
Bhonde, M.R.2
Hanski, M.L.3
Notter, M.4
Scherubl, H.5
Boland, C.R.6
-
9
-
-
0036674617
-
Live or let die: the cell's response to p53
-
Vousden K.H., and Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2 (2002) 594-604
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
11
-
-
18144416611
-
The transcriptional targets of p53 in apoptosis control
-
Yu J., and Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 331 (2005) 851-858
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 851-858
-
-
Yu, J.1
Zhang, L.2
-
12
-
-
0033552948
-
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
-
Blandino G., Levine A.J., and Oren M. Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 18 (1999) 477-485
-
(1999)
Oncogene
, vol.18
, pp. 477-485
-
-
Blandino, G.1
Levine, A.J.2
Oren, M.3
-
13
-
-
11244303546
-
Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells
-
Arango D., Wilson A.J., Shi Q., Corner G.A., Aranes M.J., Nicholas C., et al. Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells. Br J Cancer 91 (2004) 1931-1946
-
(2004)
Br J Cancer
, vol.91
, pp. 1931-1946
-
-
Arango, D.1
Wilson, A.J.2
Shi, Q.3
Corner, G.A.4
Aranes, M.J.5
Nicholas, C.6
-
14
-
-
1642327569
-
Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan
-
Boyer J., McLean E.G., Aroori S., Wilson P., McCulla A., Carey P.D., et al. Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. Clin Cancer Res 10 (2004) 2158-2167
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2158-2167
-
-
Boyer, J.1
McLean, E.G.2
Aroori, S.3
Wilson, P.4
McCulla, A.5
Carey, P.D.6
-
15
-
-
6344236877
-
Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA
-
Gourdier I., Crabbe L., Andreau K., Pau B., and Kroemer G. Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA. Oncogene 23 (2004) 7449-7457
-
(2004)
Oncogene
, vol.23
, pp. 7449-7457
-
-
Gourdier, I.1
Crabbe, L.2
Andreau, K.3
Pau, B.4
Kroemer, G.5
-
16
-
-
0037213983
-
Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines
-
Arnould S., Hennebelle I., Canal P., Bugat R., and Guichard S. Cellular determinants of oxaliplatin sensitivity in colon cancer cell lines. Eur J Cancer 39 (2003) 112-119
-
(2003)
Eur J Cancer
, vol.39
, pp. 112-119
-
-
Arnould, S.1
Hennebelle, I.2
Canal, P.3
Bugat, R.4
Guichard, S.5
-
17
-
-
2542615200
-
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
Andre T., Boni C., Mounedji-Boudiaf L., Navarro M., Tabernero J., Hickish T., et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 350 (2004) 2343-2351
-
(2004)
N Engl J Med
, vol.350
, pp. 2343-2351
-
-
Andre, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
Navarro, M.4
Tabernero, J.5
Hickish, T.6
-
18
-
-
0035859006
-
Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay
-
Maurici D., Monti P., Campomenosi P., North S., Frebourg T., Fronza G., et al. Amifostine (WR2721) restores transcriptional activity of specific p53 mutant proteins in a yeast functional assay. Oncogene 20 (2001) 3533-3540
-
(2001)
Oncogene
, vol.20
, pp. 3533-3540
-
-
Maurici, D.1
Monti, P.2
Campomenosi, P.3
North, S.4
Frebourg, T.5
Fronza, G.6
-
19
-
-
0035899332
-
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
-
Gayet J., Zhou X.P., Duval A., Rolland S., Hoang J.M., Cottu P., et al. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene 20 (2001) 5025-5032
-
(2001)
Oncogene
, vol.20
, pp. 5025-5032
-
-
Gayet, J.1
Zhou, X.P.2
Duval, A.3
Rolland, S.4
Hoang, J.M.5
Cottu, P.6
-
20
-
-
22844445482
-
Development of cell cycle active drugs for the treatment of gastrointestinal cancers: a new approach to cancer therapy
-
Schwartz GK. Development of cell cycle active drugs for the treatment of gastrointestinal cancers: a new approach to cancer therapy. J Clin Oncol 23 (2005) 4499-4508
-
(2005)
J Clin Oncol
, vol.23
, pp. 4499-4508
-
-
Schwartz GK1
-
21
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
Wang D., and Lippard S.J. Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov 4 (2005) 307-320
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
22
-
-
0041997348
-
Chemosensitivity linked to p73 function
-
Irwin M.S., Kondo K., Marin M.C., Cheng L.S., Hahn W.C., and Kaelin Jr. W.G. Chemosensitivity linked to p73 function. Cancer Cell 3 (2003) 403-410
-
(2003)
Cancer Cell
, vol.3
, pp. 403-410
-
-
Irwin, M.S.1
Kondo, K.2
Marin, M.C.3
Cheng, L.S.4
Hahn, W.C.5
Kaelin Jr., W.G.6
-
24
-
-
0036917549
-
Pharmacokinetics of oxaliplatin in humans
-
Ehrsson H., Wallin I., and Yachnin J. Pharmacokinetics of oxaliplatin in humans. Med Oncol 19 (2002) 261-265
-
(2002)
Med Oncol
, vol.19
, pp. 261-265
-
-
Ehrsson, H.1
Wallin, I.2
Yachnin J3
-
25
-
-
1842451620
-
Death without caspases, caspases without death
-
Abraham M.C., and Shaham S. Death without caspases, caspases without death. Trends Cell Biol 14 (2004) 184-193
-
(2004)
Trends Cell Biol
, vol.14
, pp. 184-193
-
-
Abraham, M.C.1
Shaham, S.2
-
26
-
-
0031593748
-
The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death
-
Basu A., and Haldar S. The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death. Mol Hum Reprod 4 (1998) 1099-1109
-
(1998)
Mol Hum Reprod
, vol.4
, pp. 1099-1109
-
-
Basu, A.1
Haldar, S.2
-
27
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman T., Lengauer C., Kinzler K.W., and Vogelstein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381 (1996) 713-716
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
28
-
-
0037169358
-
Apoptosis: a link between cancer genetics and chemotherapy
-
Johnstone R.W., Ruefli A.A., and Lowe S.W. Apoptosis: a link between cancer genetics and chemotherapy. Cell 108 (2002) 153-164
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
29
-
-
0037022606
-
Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function
-
de Vries A., Flores E.R., Miranda B., Hsieh H.M., van Oostrom C.T., Sage J., et al. Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function. Proc Natl Acad Sci USA 99 (2002) 2948-2953
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2948-2953
-
-
de Vries, A.1
Flores, E.R.2
Miranda, B.3
Hsieh, H.M.4
van Oostrom, C.T.5
Sage, J.6
-
30
-
-
0041330430
-
p53's believe it or not: lessons on transcription-independent death
-
Chipuk J.E., and Green D.R. p53's believe it or not: lessons on transcription-independent death. J Clin Immunol 23 (2003) 355-361
-
(2003)
J Clin Immunol
, vol.23
, pp. 355-361
-
-
Chipuk, J.E.1
Green, D.R.2
-
31
-
-
3242690522
-
In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
-
Erster S., Mihara M., Kim R.H., Petrenko O., and Moll U.M. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 24 (2004) 6728-6741
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6728-6741
-
-
Erster, S.1
Mihara, M.2
Kim, R.H.3
Petrenko, O.4
Moll, U.M.5
-
32
-
-
0842269242
-
p53 family members and chemoresistance in cancer: what we know and what we need to know
-
Gasco M., and Crook T. p53 family members and chemoresistance in cancer: what we know and what we need to know. Drug Resist Updat 6 (2003) 323-328
-
(2003)
Drug Resist Updat
, vol.6
, pp. 323-328
-
-
Gasco, M.1
Crook, T.2
-
33
-
-
0037119631
-
DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors
-
Zaika A.I., Slade N., Erster S.H., Sansome C., Joseph T.W., Pearl M., et al. DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors. J Exp Med 196 (2002) 765-780
-
(2002)
J Exp Med
, vol.196
, pp. 765-780
-
-
Zaika, A.I.1
Slade, N.2
Erster, S.H.3
Sansome, C.4
Joseph, T.W.5
Pearl, M.6
-
34
-
-
0035825577
-
p73 is transcriptionally regulated by DNA damage, p53, and p73
-
Chen X., Zheng Y., Zhu J., Jiang J., and Wang J. p73 is transcriptionally regulated by DNA damage, p53, and p73. Oncogene 20 (2001) 769-774
-
(2001)
Oncogene
, vol.20
, pp. 769-774
-
-
Chen, X.1
Zheng, Y.2
Zhu, J.3
Jiang, J.4
Wang, J.5
-
35
-
-
0032533514
-
The potential tumor suppressor p73 differentially regulates cellular p53 target genes
-
Zhu J., Jiang J., Zhou W., and Chen X. The potential tumor suppressor p73 differentially regulates cellular p53 target genes. Cancer Res 58 (1998) 5061-5065
-
(1998)
Cancer Res
, vol.58
, pp. 5061-5065
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Chen, X.4
-
36
-
-
0034052378
-
Adenovirus-mediated transfer of p53-related genes induces apoptosis of human cancer cells
-
Ishida S., Yamashita T., Nakaya U., and Tokino T. Adenovirus-mediated transfer of p53-related genes induces apoptosis of human cancer cells. Jpn J Cancer Res 91 (2000) 174-180
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 174-180
-
-
Ishida, S.1
Yamashita, T.2
Nakaya, U.3
Tokino, T.4
-
37
-
-
0037041392
-
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
Flores E.R., Tsai K.Y., Crowley D., Sengupta S., Yang A., McKeon F., et al. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416 (2002) 560-564
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
-
38
-
-
0035131701
-
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
-
Gaiddon C., Lokshin M., Ahn J., Zhang T., and Prives C. A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol 21 (2001) 1874-1887
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1874-1887
-
-
Gaiddon, C.1
Lokshin, M.2
Ahn, J.3
Zhang, T.4
Prives, C.5
-
39
-
-
10744230945
-
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
-
Bergamaschi D., Gasco M., Hiller L., Sullivan A., Syed N., Trigiante G., et al. p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell 3 (2003) 387-402
-
(2003)
Cancer Cell
, vol.3
, pp. 387-402
-
-
Bergamaschi, D.1
Gasco, M.2
Hiller, L.3
Sullivan, A.4
Syed, N.5
Trigiante, G.6
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