Genome-wide estimates of mutation rates and spectrum in Schizosaccharomyces pombe indicate CpG sites are highly mutagenic despite the absence of DNA methylation

G3: Genes, Genomes, Genetics

Volumn 6, Issue 1, 2016, Pages 149-160

  Behringer, Megan G ^a   Hall, David W ^a  

^a University of Georgia   (United States)

Author keywords

Cytosine mutation; Insertion bias; Mutation accumulation

Indexed keywords

PYRIMIDINE NUCLEOTIDE;

ARTICLE; BINOMIAL DISTRIBUTION; CENTROMERE; CHROMOSOME SIZE; CONTROLLED STUDY; CPG ISLAND; DEAMINATION; DNA BASE COMPOSITION; DNA METHYLATION; EFFECTIVE POPULATION SIZE; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; INDEL MUTATION; MISSENSE MUTATION; MUTATION ACCUMULATION; MUTATION RATE; NEXT GENERATION SEQUENCING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SPONTANEOUS MUTATION; FUNGAL GENOME; GENE EXPRESSION REGULATION; GENETICS; MUTATION; POINT MUTATION; SCHIZOSACCHAROMYCES;

CPG ISLANDS; DNA METHYLATION; GENE EXPRESSION; GENOME, FUNGAL; MUTAGENESIS, INSERTIONAL; MUTATION; MUTATION RATE; POINT MUTATION; SCHIZOSACCHAROMYCES; SEQUENCE DELETION;

EID: 84953775974     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.115.022129     Document Type: Article

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