Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity

PLoS Pathogens

Volumn 11, Issue 12, 2015, Pages

  Painter, Meghan M ^a   Morrison, James H ^b   Zoecklein, Laurie J ^c   Rinkoski, Tommy A ^b   Watzlawik, Jens O ^c   Papke, Louisa M ^c   Warrington, Arthur E ^c   Bieber, Allan J ^c   Matchett, William E ^a   Turkowski, Kari L ^a   Poeschla, Eric M ^b,d   Rodriguez, Moses ^c,d  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; DOUBLE STRANDED RNA; DOXYCYCLINE; MELANOMA DIFFERENTIATION ASSOCIATED PROTEIN 5; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; PROTEIN; RNA DIRECTED RNA POLYMERASE; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; VIRAL PROTEIN;

ADAPTIVE IMMUNITY; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INNATE IMMUNITY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PICORNAVIRIDAE; POINT MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; DNA MICROARRAY; FEMALE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; TRANSGENIC MOUSE; VIRUS DISEASES; VIRUS GENE;

ANIMALS; BLOTTING, WESTERN; CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENES, VIRAL; HUMANS; IMMUNITY, INNATE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PICORNAVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA REPLICASE; VIRAL PROTEINS; VIRUS DISEASES;

EID: 84953237741     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005311     Document Type: Article

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