Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

PLoS Genetics

Volumn 11, Issue 12, 2015, Pages

  van de Bunt, Martijn ^a,b   Manning Fox, Jocelyn E ^c,d   Dai, Xiaoqing ^c,d   Barrett, Amy ^a   Grey, Caleb ^c,d   Li, Lei ^c,d   Bennett, Amanda J ^a   Johnson, Paul R ^a   Rajotte, Raymond V ^c,d   Gaulton, Kyle J ^b,e   Dermitzakis, Emmanouil T ^f,g   MacDonald, Patrick E ^c,d   McCarthy, Mark I ^a,b,h   Gloyn, Anna L ^a,b,h  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

^e STANFORD UNIVERSITY   (United States)

^f UNIVERSITY OF GENEVA   (Switzerland)

^g SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^h CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; TRANSCRIPTION FACTOR; ZMIZ1 PROTEIN, HUMAN;

BIOSYNTHESIS; EXON; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PATHOLOGY; QUANTITATIVE TRAIT LOCUS; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

DIABETES MELLITUS, TYPE 2; EXONS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; QUANTITATIVE TRAIT LOCI; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84953234597     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005694     Document Type: Article

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