Human islet function following 20 years of cryogenic biobanking

Diabetologia

Volumn 58, Issue 7, 2015, Pages 1503-1512

  Manning Fox, Jocelyn E ^a,b   Lyon, James ^a,b   Dai, Xiao Qing ^a,b   Wright, Robert C ^a,b   Hayward, Julie ^a,b   van de Bunt, Martijn ^c,d   Kin, Tatsuya ^a,b   Shapiro, A M James ^a,b   McCarthy, Mark I ^c,d,e   Gloyn, Anna L ^c,d,e   Ungrin, Mark D ^f   Lakey, Jonathan R ^g   Kneteman, Norm M ^b   Warnock, Garth L ^h   Korbutt, Gregory S ^a,b   Rajotte, Raymond V ^a,b   MacDonald, Patrick E ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e CHURCHILL HOSPITAL   (United Kingdom)

^f UNIVERSITY OF CALGARY   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cryopreservation; Exocytosis; Human; Insulin; Ion channels; Islets; Secretion; Transplantation

Indexed keywords

DITHIZONE; INSULIN; LEVO GLUCOSE; TRANSCRIPTOME; HOMEODOMAIN PROTEIN; ION CHANNEL; RAG-1 PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; EXOCYTOSIS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RNA SEQUENCE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WHOLE CELL PATCH CLAMP; ANIMAL; BLOOD; DIABETES MELLITUS, EXPERIMENTAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; TISSUE BANK;

ADULT; ANIMALS; CRYOPRESERVATION; DIABETES MELLITUS, EXPERIMENTAL; EXOCYTOSIS; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ION CHANNELS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; TISSUE BANKS; TRANSCRIPTOME;

EID: 84931570902     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3598-4     Document Type: Article

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