N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway

Journal of Biological Chemistry

Volumn 289, Issue 23, 2014, Pages 15927-15941

  Johswich, Anita ^a   Longuet, Christine ^a   Pawling, Judy ^a   Rahman, Anas Abdel ^a,d   Ryczko, Michael ^a,b   Drucker, Daniel J ^a,b   Dennis, James W ^a,b,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d YARMOUK UNIVERSITY   (Jordan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; GLUCOSE; INSULIN; MAMMALS; METABOLISM; PHYSIOLOGY; POLYSACCHARIDES;

DONOR SUBSTRATES; GLUCOSE HOMEOSTASIS; GLYCOLYTIC METABOLITES; HEXOSAMINE BIOSYNTHESIS PATHWAYS; INSULIN SENSITIVITY; PRIMARY HEPATOCYTES; RECEPTOR SIGNALING; SOLUTE TRANSPORTERS;

CELL SIGNALING;

CELL PROTEIN; ECALECTIN; GLUCAGON; GLUCAGON RECEPTOR; GLYCAN DERIVATIVE; HEXOSAMINE; MGAT5 PROTEIN; N ACETYLGLUCOSAMINYLTRANSFERASE; N GLYCAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; FEMALE; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HEK293 CELL LINE; IN VIVO STUDY; INSULIN SENSITIVITY; INTRACELLULAR SIGNALING; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; RECEPTOR BINDING; RECEPTOR UPREGULATION; SENSITIVITY ANALYSIS;

GLUCAGON RECEPTOR; GLUCONEOGENESIS; GLYCOSYLATION; GLYCOSYLTRANSFERASE; GOLGI N-ACETYLGLUCOSAMINYLTRANSFERASES; METABOLISM; RECEPTOR REGULATION;

ANIMALS; CHROMATOGRAPHY, LIQUID; GLUCAGON; HEK293 CELLS; HEXOSAMINES; HUMANS; HYPOGLYCEMIA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-ACETYLGLUCOSAMINYLTRANSFERASES; POLYSACCHARIDES; RECEPTORS, GLUCAGON; TANDEM MASS SPECTROMETRY;

EID: 84902131110     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.563734     Document Type: Article

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