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Volumn 885, Issue , 2015, Pages 1-16

Lipidomic data analysis: Tutorial, practical guidelines and applications

Author keywords

Chemometrics; Classification; Data analysis; Exploration; Lipidomics; Statistics

Indexed keywords

CELL MEMBRANES; CELL SIGNALING; CHROMATOGRAPHY; CLASSIFICATION (OF INFORMATION); DATA HANDLING; DATA REDUCTION; INFORMATION ANALYSIS; LIPIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOBILE SECURITY; MOLECULAR BIOLOGY; MULTIVARIANT ANALYSIS; NATURAL RESOURCES EXPLORATION; STATISTICS;

EID: 84952877382     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2015.02.068     Document Type: Review
Times cited : (96)

References (145)
  • 2
    • 84896897706 scopus 로고    scopus 로고
    • Lipidomics of Alzheimer's disease
    • Touboul D., Gaudin M. Lipidomics of Alzheimer's disease. Bioanalysis 2014, 6(4):541-561.
    • (2014) Bioanalysis , vol.6 , Issue.4 , pp. 541-561
    • Touboul, D.1    Gaudin, M.2
  • 3
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis A.J. Atherosclerosis. Nature 2000, 407(6801):233-241.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 233-241
    • Lusis, A.J.1
  • 4
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger R.H. Lipotoxic diseases. Annu. Rev. Med. 2002, 53:319-336.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 5
    • 84904732950 scopus 로고    scopus 로고
    • Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment
    • Ackerman D., Simon M.C. Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment. Trends Cell Biol. 2014, 24(8):472-478.
    • (2014) Trends Cell Biol. , vol.24 , Issue.8 , pp. 472-478
    • Ackerman, D.1    Simon, M.C.2
  • 6
    • 84874860388 scopus 로고    scopus 로고
    • Alterations of brain membranes in schizophrenia: impact of phospholipase A(2)
    • Schaeffer E.L., Gattaz W.F., Eckert G.P. Alterations of brain membranes in schizophrenia: impact of phospholipase A(2). Curr. Top. Med. Chem. 2012, 12(21):2314-2323.
    • (2012) Curr. Top. Med. Chem. , vol.12 , Issue.21 , pp. 2314-2323
    • Schaeffer, E.L.1    Gattaz, W.F.2    Eckert, G.P.3
  • 8
    • 63049136500 scopus 로고    scopus 로고
    • From lipids analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part II: analytical lipidomics
    • Navas-Iglesias N., Carrasco-Pancorbo A., Cuadros-Rodríguez L. From lipids analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part II: analytical lipidomics. TrAC, Trends Anal. Chem. 2009, 28(4):393-403.
    • (2009) TrAC, Trends Anal. Chem. , vol.28 , Issue.4 , pp. 393-403
    • Navas-Iglesias, N.1    Carrasco-Pancorbo, A.2    Cuadros-Rodríguez, L.3
  • 9
    • 84882257775 scopus 로고    scopus 로고
    • Lipidomics as a principal tool for advancing biomedical research
    • Lam S.M., Shui G. Lipidomics as a principal tool for advancing biomedical research. J. Genet. Genomics 2013, 40(8):375-390.
    • (2013) J. Genet. Genomics , vol.40 , Issue.8 , pp. 375-390
    • Lam, S.M.1    Shui, G.2
  • 10
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J., Lees M., Stanley G.H.S. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 1957, 226(1):497-509.
    • (1957) J. Biol. Chem. , vol.226 , Issue.1 , pp. 497-509
    • Folch, J.1    Lees, M.2    Stanley, G.H.S.3
  • 11
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh E.G., Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959, 37(8):911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , Issue.8 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 12
    • 50049102248 scopus 로고    scopus 로고
    • Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
    • Matyash V., Liebisch G., Kurzchalia T.V., Shevchenko A., Schwudke D. Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J. Lipid Res. 2008, 49(5):1137-1146.
    • (2008) J. Lipid Res. , vol.49 , Issue.5 , pp. 1137-1146
    • Matyash, V.1    Liebisch, G.2    Kurzchalia, T.V.3    Shevchenko, A.4    Schwudke, D.5
  • 13
    • 84898891503 scopus 로고    scopus 로고
    • Lipidomics: potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease
    • Meikle P.J., Wong G., Barlow C.K., Kingwell B.A. Lipidomics: potential role in risk prediction and therapeutic monitoring for diabetes and cardiovascular disease. Pharmacol. Ther. 2014, 143(1):12-23.
    • (2014) Pharmacol. Ther. , vol.143 , Issue.1 , pp. 12-23
    • Meikle, P.J.1    Wong, G.2    Barlow, C.K.3    Kingwell, B.A.4
  • 14
    • 34547556301 scopus 로고    scopus 로고
    • LIPID MAPS online tools for lipid research
    • Web Server issue
    • Fahy E., Sud M., Cotter D., Subramaniam S. LIPID MAPS online tools for lipid research. Nucleic Acids Res. 2007, 35(Web Server issue):W606-W612.
    • (2007) Nucleic Acids Res. , vol.35 , pp. W606-W612
    • Fahy, E.1    Sud, M.2    Cotter, D.3    Subramaniam, S.4
  • 18
    • 32444433438 scopus 로고    scopus 로고
    • Symbiosis of chemometrics and metabolomics: past, present, and future
    • Van Der Greef J., Smilde A.K. Symbiosis of chemometrics and metabolomics: past, present, and future. J. Chemometr. 2005, 19(5-7):376-386.
    • (2005) J. Chemometr. , vol.19 , Issue.5-7 , pp. 376-386
    • Van Der Greef, J.1    Smilde, A.K.2
  • 20
    • 84897403587 scopus 로고    scopus 로고
    • Statistical methods for the analysis of high-throughput metabolomics data
    • Bartel J., Krumsiek J., Theis F.J. Statistical methods for the analysis of high-throughput metabolomics data. Comput. Struct. Biotechnol. J. 2013, 4(5):e201301009.
    • (2013) Comput. Struct. Biotechnol. J. , vol.4 , Issue.5 , pp. e201301009
    • Bartel, J.1    Krumsiek, J.2    Theis, F.J.3
  • 21
    • 84891801016 scopus 로고    scopus 로고
    • Multidimensional approaches to NMR-based metabolomics
    • Bingol K., Brüschweiler R. Multidimensional approaches to NMR-based metabolomics. Anal. Chem. 2014, 86(1):47-57.
    • (2014) Anal. Chem. , vol.86 , Issue.1 , pp. 47-57
    • Bingol, K.1    Brüschweiler, R.2
  • 22
    • 77249175352 scopus 로고    scopus 로고
    • Knowledge discovery in metabolomics: an overview of MS data handling
    • Boccard J., Veuthey J.L., Rudaz S. Knowledge discovery in metabolomics: an overview of MS data handling. J. Sep. Sci. 2010, 33(3):290-304.
    • (2010) J. Sep. Sci. , vol.33 , Issue.3 , pp. 290-304
    • Boccard, J.1    Veuthey, J.L.2    Rudaz, S.3
  • 24
    • 79956328118 scopus 로고    scopus 로고
    • Multivariate methods in metabolomics - from pre-processing to dimension reduction and statistical analysis
    • Liland K.H. Multivariate methods in metabolomics - from pre-processing to dimension reduction and statistical analysis. TrAC, Trends Anal. Chem. 2011, 30(6):827-841.
    • (2011) TrAC, Trends Anal. Chem. , vol.30 , Issue.6 , pp. 827-841
    • Liland, K.H.1
  • 26
    • 84907015010 scopus 로고    scopus 로고
    • Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
    • Cajka T., Fiehn O. Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry. Trends Anal. Chem. 2014, 61:192-206.
    • (2014) Trends Anal. Chem. , vol.61 , pp. 192-206
    • Cajka, T.1    Fiehn, O.2
  • 27
    • 84891794084 scopus 로고    scopus 로고
    • Analytical methods in lipidomics and their applications
    • Li M., Yang L., Bai Y., Liu H. Analytical methods in lipidomics and their applications. Anal. Chem. 2014, 86(1):161-175.
    • (2014) Anal. Chem. , vol.86 , Issue.1 , pp. 161-175
    • Li, M.1    Yang, L.2    Bai, Y.3    Liu, H.4
  • 28
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
    • Han X., Gross R.W. Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom. Rev. 2005, 24(3):367-412.
    • (2005) Mass Spectrom. Rev. , vol.24 , Issue.3 , pp. 367-412
    • Han, X.1    Gross, R.W.2
  • 29
    • 0031304362 scopus 로고    scopus 로고
    • Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS
    • Caprioli R.M., Farmer T.B., Gile J. Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS. Anal. Chem. 1997, 69(23):4751-4760.
    • (1997) Anal. Chem. , vol.69 , Issue.23 , pp. 4751-4760
    • Caprioli, R.M.1    Farmer, T.B.2    Gile, J.3
  • 31
    • 84867336104 scopus 로고    scopus 로고
    • NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review
    • Smolinska A., Blanchet L., Buydens L.M.C., Wijmenga S.S. NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review. Anal. Chim. Acta 2012, 750:82-97.
    • (2012) Anal. Chim. Acta , vol.750 , pp. 82-97
    • Smolinska, A.1    Blanchet, L.2    Buydens, L.M.C.3    Wijmenga, S.S.4
  • 33
    • 67849106535 scopus 로고    scopus 로고
    • MetaboAnalyst: a web server for metabolomic data analysis and interpretation
    • Xia J., Psychogios N., Young N., Wishart D.S. MetaboAnalyst: a web server for metabolomic data analysis and interpretation. Nucleic Acids Res. 2009, 37(Suppl. 2):W652-W660.
    • (2009) Nucleic Acids Res. , vol.37 , pp. W652-W660
    • Xia, J.1    Psychogios, N.2    Young, N.3    Wishart, D.S.4
  • 37
    • 0028931857 scopus 로고
    • Multiple significance tests - the Bonferroni method
    • Bland J.M., Altman D.G. Multiple significance tests - the Bonferroni method. Br. Med. J. 1995, 310(6973):170.
    • (1995) Br. Med. J. , vol.310 , Issue.6973 , pp. 170
    • Bland, J.M.1    Altman, D.G.2
  • 38
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - a practical and powerful approach to multiple testing
    • Benjamini Y., Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J. R. Stat. Soc. Series B Methodol. 1995, 57(1):289-300.
    • (1995) J. R. Stat. Soc. Series B Methodol. , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 39
    • 0345822598 scopus 로고    scopus 로고
    • The positive false discovery rate: a Bayesian interpretation and the q-value
    • Storey J.D. The positive false discovery rate: a Bayesian interpretation and the q-value. Ann. Statist. 2003, 31(6):2013-2035.
    • (2003) Ann. Statist. , vol.31 , Issue.6 , pp. 2013-2035
    • Storey, J.D.1
  • 40
    • 84943987463 scopus 로고
    • Multiple comparisons among means
    • Dunn O.J. Multiple comparisons among means. J. Am. Stat. Assoc. 1961, 56(293):52-64.
    • (1961) J. Am. Stat. Assoc. , vol.56 , Issue.293 , pp. 52-64
    • Dunn, O.J.1
  • 41
    • 0026958584 scopus 로고
    • Principal component analysis and exploratory factor analysis
    • Joliffe I.T., Morgan B.J. Principal component analysis and exploratory factor analysis. Stat. Methods Med. Res. 1992, 1(1):69-95.
    • (1992) Stat. Methods Med. Res. , vol.1 , Issue.1 , pp. 69-95
    • Joliffe, I.T.1    Morgan, B.J.2
  • 44
    • 20444496575 scopus 로고    scopus 로고
    • Analysis of variance-principal component analysis: a soft tool for proteomic discovery
    • Harrington P.D.B., Vieira N.E., Espinoza J., Nien J.K., Romero R., Yergey A.L. Analysis of variance-principal component analysis: a soft tool for proteomic discovery. Anal. Chim. Acta 2005, 544(1-2 Spec. Iss):118-127.
    • (2005) Anal. Chim. Acta , vol.544 , Issue.1-2 , pp. 118-127
    • Harrington, P.D.B.1    Vieira, N.E.2    Espinoza, J.3    Nien, J.K.4    Romero, R.5    Yergey, A.L.6
  • 46
    • 0003430544 scopus 로고    scopus 로고
    • Finding groups in data: an introduction to cluster analysis
    • John Wiley & Sons, Hoboken, NJ, US
    • Kaufman L., Rousseeuw P.J. Finding groups in data: an introduction to cluster analysis. Wiley Series in Probability and Statistics 2005, John Wiley & Sons, Hoboken, NJ, US.
    • (2005) Wiley Series in Probability and Statistics
    • Kaufman, L.1    Rousseeuw, P.J.2
  • 47
    • 33646023117 scopus 로고    scopus 로고
    • An introduction to ROC analysis
    • Fawcett T. An introduction to ROC analysis. Pattern Recognit. Lett. 2006, 27(8):861-874.
    • (2006) Pattern Recognit. Lett. , vol.27 , Issue.8 , pp. 861-874
    • Fawcett, T.1
  • 48
    • 85164278893 scopus 로고
    • Partial least squares analysis with cross-validation for the two-class problem: a Monte Carlo study
    • Ståhle L., Wold S. Partial least squares analysis with cross-validation for the two-class problem: a Monte Carlo study. J. Chemometr. 1987, 1(3):185-196.
    • (1987) J. Chemometr. , vol.1 , Issue.3 , pp. 185-196
    • Ståhle, L.1    Wold, S.2
  • 49
    • 11144325691 scopus 로고
    • Partial least-squares regression - a tutorial
    • Geladi P., Kowalski B.R. Partial least-squares regression - a tutorial. Anal. Chim. Acta 1986, 185:1-17.
    • (1986) Anal. Chim. Acta , vol.185 , pp. 1-17
    • Geladi, P.1    Kowalski, B.R.2
  • 50
    • 0037350844 scopus 로고    scopus 로고
    • Partial least squares for discrimination
    • Barker W., Rayens M. Partial least squares for discrimination. J. Chemometr. 2003, 17(3):166-173.
    • (2003) J. Chemometr. , vol.17 , Issue.3 , pp. 166-173
    • Barker, W.1    Rayens, M.2
  • 51
    • 21244436700 scopus 로고    scopus 로고
    • Performance of some variable selection methods when multicollinearity is present
    • Chong C.H., Jun I.G. Performance of some variable selection methods when multicollinearity is present. Chemometr. Intell. Lab. Syst. 2005, 78(1):103-112.
    • (2005) Chemometr. Intell. Lab. Syst. , vol.78 , Issue.1 , pp. 103-112
    • Chong, C.H.1    Jun, I.G.2
  • 53
    • 34249335649 scopus 로고    scopus 로고
    • OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification
    • Bylesjo M., Rantalainen M., Cloarec O., Nicholson J.K., Holmes E., Trygg J. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification. J. Chemometr. 2006, 20(8-10):341-351.
    • (2006) J. Chemometr. , vol.20 , Issue.8-10 , pp. 341-351
    • Bylesjo, M.1    Rantalainen, M.2    Cloarec, O.3    Nicholson, J.K.4    Holmes, E.5    Trygg, J.6
  • 54
    • 3242731235 scopus 로고    scopus 로고
    • Some theoretical properties of the O-PLS method
    • Verron T., Sabatier R., Joffre R. Some theoretical properties of the O-PLS method. J. Chemometr. 2004, 18(2):62-68.
    • (2004) J. Chemometr. , vol.18 , Issue.2 , pp. 62-68
    • Verron, T.1    Sabatier, R.2    Joffre, R.3
  • 56
    • 36949021555 scopus 로고    scopus 로고
    • Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data
    • Bylesjo M., Eriksson D., Kusano M., Moritz T., Trygg J. Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data. Plant J. 2007, 52(6):1181-1191.
    • (2007) Plant J. , vol.52 , Issue.6 , pp. 1181-1191
    • Bylesjo, M.1    Eriksson, D.2    Kusano, M.3    Moritz, T.4    Trygg, J.5
  • 58
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • Breiman L. Random forests. Mach. Learn. 2001, 45(1):5-32.
    • (2001) Mach. Learn. , vol.45 , Issue.1 , pp. 5-32
    • Breiman, L.1
  • 59
    • 34249753618 scopus 로고
    • Support-vector networks
    • Cortes C., Vapnik V. Support-vector networks. Mach. Learn. 1995, 20(3):273-297.
    • (1995) Mach. Learn. , vol.20 , Issue.3 , pp. 273-297
    • Cortes, C.1    Vapnik, V.2
  • 60
    • 33846240326 scopus 로고    scopus 로고
    • Statistical strategies for avoiding false discoveries in metabolomics and related experiments
    • Broadhurst D.I., Kell D.B. Statistical strategies for avoiding false discoveries in metabolomics and related experiments. Metabolomics 2006, 2(4):171-196.
    • (2006) Metabolomics , vol.2 , Issue.4 , pp. 171-196
    • Broadhurst, D.I.1    Kell, D.B.2
  • 62
    • 84861915827 scopus 로고    scopus 로고
    • XCMS online: a web-based platform to process untargeted metabolomic data
    • Tautenhahn R., Patti G.J., Rinehart D., Siuzdak G. XCMS online: a web-based platform to process untargeted metabolomic data. Anal. Chem. 2012, 84(11):5035-5039.
    • (2012) Anal. Chem. , vol.84 , Issue.11 , pp. 5035-5039
    • Tautenhahn, R.1    Patti, G.J.2    Rinehart, D.3    Siuzdak, G.4
  • 63
    • 84878044033 scopus 로고    scopus 로고
    • MALDI imaging mass spectrometry: statistical data analysis and current computational challenges
    • Alexandrov T. MALDI imaging mass spectrometry: statistical data analysis and current computational challenges. BMC Bioinformatics 2012, 13(Suppl. 16):S11.
    • (2012) BMC Bioinformatics , vol.13 , pp. S11
    • Alexandrov, T.1
  • 64
    • 84858710198 scopus 로고    scopus 로고
    • Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies
    • Kamleh M.A., Ebbels T.M.D., Spagou K., Masson P., Want E.J. Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies. Anal. Chem. 2012, 84(6):2670-2677.
    • (2012) Anal. Chem. , vol.84 , Issue.6 , pp. 2670-2677
    • Kamleh, M.A.1    Ebbels, T.M.D.2    Spagou, K.3    Masson, P.4    Want, E.J.5
  • 65
    • 84860380628 scopus 로고    scopus 로고
    • Missing values in mass spectrometry based metabolomics: an undervalued step in the data processing pipeline
    • Hrydziuszko M.R., Viant O. Missing values in mass spectrometry based metabolomics: an undervalued step in the data processing pipeline. Metabolomics 2012, 8:161-174.
    • (2012) Metabolomics , vol.8 , pp. 161-174
    • Hrydziuszko, M.R.1    Viant, O.2
  • 68
    • 67849085414 scopus 로고    scopus 로고
    • A shotgun lipidomics study of a putative lysophosphatidic acid acyl transferase (PlsC) in Sinorhizobium meliloti
    • Basconcillo L.S., Zaheer R., Finan T.M., McCarry B.E. A shotgun lipidomics study of a putative lysophosphatidic acid acyl transferase (PlsC) in Sinorhizobium meliloti. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2009, 877(26):2873-2882.
    • (2009) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.877 , Issue.26 , pp. 2873-2882
    • Basconcillo, L.S.1    Zaheer, R.2    Finan, T.M.3    McCarry, B.E.4
  • 69
    • 84874565816 scopus 로고    scopus 로고
    • Pollen lipidomics: lipid profiling exposes a notable diversity in 22 allergenic pollen and potential biomarkers of the allergic immune response
    • Bashir M.E., Lui J.H., Palnivelu R., Naclerio R.M., Preuss D. Pollen lipidomics: lipid profiling exposes a notable diversity in 22 allergenic pollen and potential biomarkers of the allergic immune response. PLoS One 2013, 8(2):e57566.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e57566
    • Bashir, M.E.1    Lui, J.H.2    Palnivelu, R.3    Naclerio, R.M.4    Preuss, D.5
  • 70
    • 84873347035 scopus 로고    scopus 로고
    • Lipidomics and in vitro azole resistance in Candida albicans
    • Singh A., Mahto K.K., Prasad R. Lipidomics and in vitro azole resistance in Candida albicans. OMICS 2013, 17(2):84-93.
    • (2013) OMICS , vol.17 , Issue.2 , pp. 84-93
    • Singh, A.1    Mahto, K.K.2    Prasad, R.3
  • 72
    • 84883462211 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism: lipid raft composition and myelin protein synthesis
    • Camacho A., Huang J.K., Delint-Ramirez I., Yew Tan C., Fuller M., Lelliott C.J., Vidal-Puig A., Franklin R.J. Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism: lipid raft composition and myelin protein synthesis. Eur. J. Neurosci. 2013, 38(5):2672-2683.
    • (2013) Eur. J. Neurosci. , vol.38 , Issue.5 , pp. 2672-2683
    • Camacho, A.1    Huang, J.K.2    Delint-Ramirez, I.3    Yew Tan, C.4    Fuller, M.5    Lelliott, C.J.6    Vidal-Puig, A.7    Franklin, R.J.8
  • 74
    • 79960659221 scopus 로고    scopus 로고
    • A targeted lipidomics approach to the study of eicosanoid release in synovial joints
    • de Grauw J.C., van de Lest C.H., van Weeren P.R. A targeted lipidomics approach to the study of eicosanoid release in synovial joints. Arthritis Res. Ther. 2011, 13(4):R123.
    • (2011) Arthritis Res. Ther. , vol.13 , Issue.4 , pp. R123
    • de Grauw, J.C.1    van de Lest, C.H.2    van Weeren, P.R.3
  • 75
    • 84885559250 scopus 로고    scopus 로고
    • Loss of beta-carotene 15,15'-oxygenase in developing mouse tissues alters esterification of retinol, cholesterol and diacylglycerols
    • Dixon J.L., Kim Y.K., Brinker A., Quadro L. Loss of beta-carotene 15,15'-oxygenase in developing mouse tissues alters esterification of retinol, cholesterol and diacylglycerols. Biochim. Biophys. Acta 2014, 1841(1):34-43.
    • (2014) Biochim. Biophys. Acta , vol.1841 , Issue.1 , pp. 34-43
    • Dixon, J.L.1    Kim, Y.K.2    Brinker, A.3    Quadro, L.4
  • 76
    • 84893175304 scopus 로고    scopus 로고
    • Phospholipid composition and kinetics in different endobronchial fractions from healthy volunteers
    • Dushianthan A., Goss V., Cusack R., Grocott M.P., Postle A.D. Phospholipid composition and kinetics in different endobronchial fractions from healthy volunteers. BMC Pulm. Med. 2014, 14:10.
    • (2014) BMC Pulm. Med. , vol.14 , pp. 10
    • Dushianthan, A.1    Goss, V.2    Cusack, R.3    Grocott, M.P.4    Postle, A.D.5
  • 77
    • 84903737907 scopus 로고    scopus 로고
    • Role of plastoglobules in metabolite repair in the tocopherol redox cycle
    • Eugeni Piller L., Glauser G., Kessler F., Besagni C. Role of plastoglobules in metabolite repair in the tocopherol redox cycle. Front. Plant Sci. 2014, 5:298.
    • (2014) Front. Plant Sci. , vol.5 , pp. 298
    • Eugeni Piller, L.1    Glauser, G.2    Kessler, F.3    Besagni, C.4
  • 81
    • 84878754400 scopus 로고    scopus 로고
    • Levels of Arabidopsis thaliana leaf phosphatidic acids, phosphatidylserines, and most trienoate-containing polar lipid molecular species increase during the dark period of the diurnal cycle
    • Maatta S., Scheu B., Roth M.R., Tamura P., Li M., Williams T.D., Wang X., Welti R. Levels of Arabidopsis thaliana leaf phosphatidic acids, phosphatidylserines, and most trienoate-containing polar lipid molecular species increase during the dark period of the diurnal cycle. Front. Plant Sci. 2012, 3:49.
    • (2012) Front. Plant Sci. , vol.3 , pp. 49
    • Maatta, S.1    Scheu, B.2    Roth, M.R.3    Tamura, P.4    Li, M.5    Williams, T.D.6    Wang, X.7    Welti, R.8
  • 82
    • 84896597381 scopus 로고    scopus 로고
    • Ubiquinone accumulation improves osmotic-stress tolerance in Escherichia coli
    • Sevin D.C., Sauer U. Ubiquinone accumulation improves osmotic-stress tolerance in Escherichia coli. Nat. Chem. Biol. 2014, 10(4):266-272.
    • (2014) Nat. Chem. Biol. , vol.10 , Issue.4 , pp. 266-272
    • Sevin, D.C.1    Sauer, U.2
  • 84
    • 84901070266 scopus 로고    scopus 로고
    • Quantitation of phosphatidic acid and lysophosphatidic acid molecular species using hydrophilic interaction liquid chromatography coupled to electrospray ionization high resolution mass spectrometry
    • Triebl A., Troetzmueller M., Eberl A., Hanel P., Hartler J., Koefeler H.C. Quantitation of phosphatidic acid and lysophosphatidic acid molecular species using hydrophilic interaction liquid chromatography coupled to electrospray ionization high resolution mass spectrometry. J. Chromatogr. A 2014, 1347:104-110.
    • (2014) J. Chromatogr. A , vol.1347 , pp. 104-110
    • Triebl, A.1    Troetzmueller, M.2    Eberl, A.3    Hanel, P.4    Hartler, J.5    Koefeler, H.C.6
  • 86
    • 79955777587 scopus 로고
    • Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints
    • Singh A., Prasad R. Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints. PLoS One 1926, 6:e19266.
    • (1926) PLoS One , vol.6 , pp. e19266
    • Singh, A.1    Prasad, R.2
  • 87
    • 84869069944 scopus 로고    scopus 로고
    • Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics
    • Zhou X., Mao J., Ai J., Deng Y., Roth M.R., Pound C., Henegar J., Welti R., Bigler S.A. Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics. PLoS One 2012, 7(11):e48889.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e48889
    • Zhou, X.1    Mao, J.2    Ai, J.3    Deng, Y.4    Roth, M.R.5    Pound, C.6    Henegar, J.7    Welti, R.8    Bigler, S.A.9
  • 90
    • 84904196608 scopus 로고    scopus 로고
    • Monitoring time-dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry
    • Patterson N.H., Thomas A., Chaurand P. Monitoring time-dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry. J. Mass Spectrom. 2014, 49(7):622-627.
    • (2014) J. Mass Spectrom. , vol.49 , Issue.7 , pp. 622-627
    • Patterson, N.H.1    Thomas, A.2    Chaurand, P.3
  • 91
    • 77955375161 scopus 로고    scopus 로고
    • A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences
    • Caesar R., Manieri M., Kelder T., Boekschoten M., Evelo C., Muller M., Kooistra T., Cinti S., Kleemann R., Drevon C.A. A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences. PLoS One 2010, 5(7):e11525.
    • (2010) PLoS One , vol.5 , Issue.7 , pp. e11525
    • Caesar, R.1    Manieri, M.2    Kelder, T.3    Boekschoten, M.4    Evelo, C.5    Muller, M.6    Kooistra, T.7    Cinti, S.8    Kleemann, R.9    Drevon, C.A.10
  • 93
    • 79955606534 scopus 로고    scopus 로고
    • Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype
    • Sanak M., Gielicz A., Bochenek G., Kaszuba M., Nizankowska-Mogilnicka E., Szczeklik A. Targeted eicosanoid lipidomics of exhaled breath condensate provide a distinct pattern in the aspirin-intolerant asthma phenotype. J. Allergy Clin. Immunol. 2011, 127:1141-1147. e1142.
    • (2011) J. Allergy Clin. Immunol. , vol.127 , pp. 1141-1147
    • Sanak, M.1    Gielicz, A.2    Bochenek, G.3    Kaszuba, M.4    Nizankowska-Mogilnicka, E.5    Szczeklik, A.6
  • 98
    • 84890115095 scopus 로고    scopus 로고
    • Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis
    • Cheng H., Wang M., Li J.L., Cairns N.J., Han X. Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis. J. Neurochem. 2013, 127(6):733-738.
    • (2013) J. Neurochem. , vol.127 , Issue.6 , pp. 733-738
    • Cheng, H.1    Wang, M.2    Li, J.L.3    Cairns, N.J.4    Han, X.5
  • 99
    • 84914141633 scopus 로고    scopus 로고
    • Novel approach for analysis of bronchoalveolar lavage fluid (BALF) using HPLC-QTOF-MS-based lipidomics: lipid levels in asthmatics and corticosteroid-treated asthmatic patients
    • Kang Y.P., Lee W.J., Hong J.Y., Lee S.B., Park J.H., Kim D., Park S., Park C.-S., Park S.-W., Kwon S.W. Novel approach for analysis of bronchoalveolar lavage fluid (BALF) using HPLC-QTOF-MS-based lipidomics: lipid levels in asthmatics and corticosteroid-treated asthmatic patients. J. Proteome Res. 2014, 13(9):3919-3929.
    • (2014) J. Proteome Res. , vol.13 , Issue.9 , pp. 3919-3929
    • Kang, Y.P.1    Lee, W.J.2    Hong, J.Y.3    Lee, S.B.4    Park, J.H.5    Kim, D.6    Park, S.7    Park, C.-S.8    Park, S.-W.9    Kwon, S.W.10
  • 102
    • 84908180728 scopus 로고    scopus 로고
    • Isoenergetic diets differing in their n-3 fatty acid and polyphenol content reflect different plasma and HDL-fraction lipidomic profiles in subjects at high cardiovascular risk
    • Bondia-Pons I., Poho P., Bozzetto L., Vetrani C., Patti L., Aura A.-M., Annuzzi G., Hyotylainen T., Rivellese A.A., Oresic M. Isoenergetic diets differing in their n-3 fatty acid and polyphenol content reflect different plasma and HDL-fraction lipidomic profiles in subjects at high cardiovascular risk. Mol. Nutr. Food Res. 2014, 58(9):1873-1882.
    • (2014) Mol. Nutr. Food Res. , vol.58 , Issue.9 , pp. 1873-1882
    • Bondia-Pons, I.1    Poho, P.2    Bozzetto, L.3    Vetrani, C.4    Patti, L.5    Aura, A.-M.6    Annuzzi, G.7    Hyotylainen, T.8    Rivellese, A.A.9    Oresic, M.10
  • 104
    • 84903784901 scopus 로고    scopus 로고
    • Lipidomics reveals mitochondrial membrane remodeling associated with acute thermoregulation in a rodent with a wide thermoneutral zone
    • Pan Q., Li M., Shi Y.-L., Liu H., Speakman J.R., Wang D.-H. Lipidomics reveals mitochondrial membrane remodeling associated with acute thermoregulation in a rodent with a wide thermoneutral zone. Lipids 2014, 49(7):715-730.
    • (2014) Lipids , vol.49 , Issue.7 , pp. 715-730
    • Pan, Q.1    Li, M.2    Shi, Y.-L.3    Liu, H.4    Speakman, J.R.5    Wang, D.-H.6
  • 105
    • 84862533697 scopus 로고    scopus 로고
    • Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes
    • Stahlman M., Pham H.T., Adiels M., Mitchell T.W., Blanksby S.J., Fagerberg B., Ekroos K., Boren J. Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes. Diabetologia 2012, 55(4):1156-1166.
    • (2012) Diabetologia , vol.55 , Issue.4 , pp. 1156-1166
    • Stahlman, M.1    Pham, H.T.2    Adiels, M.3    Mitchell, T.W.4    Blanksby, S.J.5    Fagerberg, B.6    Ekroos, K.7    Boren, J.8
  • 107
    • 84883529185 scopus 로고    scopus 로고
    • Effects of light intensity and nitrogen starvation on glycerolipid, glycerophospholipid, and carotenoid composition in Dunaliella tertiolecta culture
    • Kim S.H., Liu K.H., Lee S.Y., Hong S.J., Cho B.K., Lee H., Lee C.G., Choi H.K. Effects of light intensity and nitrogen starvation on glycerolipid, glycerophospholipid, and carotenoid composition in Dunaliella tertiolecta culture. PLoS One 2013, 8(9):e72415.
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e72415
    • Kim, S.H.1    Liu, K.H.2    Lee, S.Y.3    Hong, S.J.4    Cho, B.K.5    Lee, H.6    Lee, C.G.7    Choi, H.K.8
  • 110
    • 84895069147 scopus 로고    scopus 로고
    • Selenium bioavailability from shrimps (Penaeus vannamei Boone) and its effect on the metabolism of phospholipid and cholesterol ester
    • Yu Y., Zhang F., Lu D., Zhang H. Selenium bioavailability from shrimps (Penaeus vannamei Boone) and its effect on the metabolism of phospholipid and cholesterol ester. J. Funct. Foods 2014, 6:186-195.
    • (2014) J. Funct. Foods , vol.6 , pp. 186-195
    • Yu, Y.1    Zhang, F.2    Lu, D.3    Zhang, H.4
  • 112
    • 84901819081 scopus 로고    scopus 로고
    • NMR- and MS-based metabolomics: various organ responses following naphthalene intervention
    • Ling Y.S., Liang H.-J., Chung M.-H., Lin M.-H., Lin C.-Y. NMR- and MS-based metabolomics: various organ responses following naphthalene intervention. Mol. Biosyst. 2014, 10(7):1918-1931.
    • (2014) Mol. Biosyst. , vol.10 , Issue.7 , pp. 1918-1931
    • Ling, Y.S.1    Liang, H.-J.2    Chung, M.-H.3    Lin, M.-H.4    Lin, C.-Y.5
  • 113
    • 67650669263 scopus 로고    scopus 로고
    • Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patients
    • Graessler J., Schwudke D., Schwarz P.E., Herzog R., Shevchenko A., Bornstein S.R. Top-down lipidomics reveals ether lipid deficiency in blood plasma of hypertensive patients. PLoS One 2009, 4(7):e6261.
    • (2009) PLoS One , vol.4 , Issue.7 , pp. e6261
    • Graessler, J.1    Schwudke, D.2    Schwarz, P.E.3    Herzog, R.4    Shevchenko, A.5    Bornstein, S.R.6
  • 117
    • 84895871612 scopus 로고    scopus 로고
    • Tributyltin (TBT) induces oxidative stress and modifies lipid profile in the filamentous fungus Cunninghamella elegans
    • Bernat P., Gajewska E., Szewczyk R., Slaba M., Dlugonski J. Tributyltin (TBT) induces oxidative stress and modifies lipid profile in the filamentous fungus Cunninghamella elegans. Environ. Sci. Pollut. Res. Int. 2014, 21(6):4228-4235.
    • (2014) Environ. Sci. Pollut. Res. Int. , vol.21 , Issue.6 , pp. 4228-4235
    • Bernat, P.1    Gajewska, E.2    Szewczyk, R.3    Slaba, M.4    Dlugonski, J.5
  • 118
    • 84876937205 scopus 로고    scopus 로고
    • Myocardial lipidomics profiling delineate the toxicity of traditional Chinese medicine Aconiti Lateralis radix praeparata
    • Cai Y., Gao Y., Tan G., Wu S., Dong X., Lou Z., Zhu Z., Chai Y. Myocardial lipidomics profiling delineate the toxicity of traditional Chinese medicine Aconiti Lateralis radix praeparata. J. Ethnopharmacol. 2013, 147(2):349-356.
    • (2013) J. Ethnopharmacol. , vol.147 , Issue.2 , pp. 349-356
    • Cai, Y.1    Gao, Y.2    Tan, G.3    Wu, S.4    Dong, X.5    Lou, Z.6    Zhu, Z.7    Chai, Y.8
  • 119
    • 84888256463 scopus 로고    scopus 로고
    • Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry
    • Chen S., Wei C., Gao P., Kong H., Jia Z., Hu C., Dai W., Wu Y., Xu G. Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry. J. Pharm. Biomed. Anal. 2014, 89:122-129.
    • (2014) J. Pharm. Biomed. Anal. , vol.89 , pp. 122-129
    • Chen, S.1    Wei, C.2    Gao, P.3    Kong, H.4    Jia, Z.5    Hu, C.6    Dai, W.7    Wu, Y.8    Xu, G.9
  • 120
    • 84883553861 scopus 로고    scopus 로고
    • Versatile lipid profiling by liquid chromatography-high resolution mass spectrometry using all ion fragmentation and polarity switching: preliminary application for serum samples phenotyping related to canine mammary cancer
    • Gallart-Ayala H., Courant F., Severe S., Antignac J.P., Morio F., Abadie J., Le Bizec B. Versatile lipid profiling by liquid chromatography-high resolution mass spectrometry using all ion fragmentation and polarity switching: preliminary application for serum samples phenotyping related to canine mammary cancer. Anal. Chim. Acta 2013, 796:75-83.
    • (2013) Anal. Chim. Acta , vol.796 , pp. 75-83
    • Gallart-Ayala, H.1    Courant, F.2    Severe, S.3    Antignac, J.P.4    Morio, F.5    Abadie, J.6    Le Bizec, B.7
  • 122
    • 84893180445 scopus 로고    scopus 로고
    • The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism
    • Koulman A., Prentice P., Wong M.C.Y., Matthews L., Bond N.J., Eiden M., Griffin J.L., Dunger D.B. The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism. Metabolomics 2014, 10(5):1018-1025.
    • (2014) Metabolomics , vol.10 , Issue.5 , pp. 1018-1025
    • Koulman, A.1    Prentice, P.2    Wong, M.C.Y.3    Matthews, L.4    Bond, N.J.5    Eiden, M.6    Griffin, J.L.7    Dunger, D.B.8
  • 129
    • 84863001304 scopus 로고    scopus 로고
    • Comparative lipidomics in clinical isolates of Candida albicans reveal crosstalk between mitochondria, cell wall integrity and azole resistance
    • Singh A., Yadav V., Prasad R. Comparative lipidomics in clinical isolates of Candida albicans reveal crosstalk between mitochondria, cell wall integrity and azole resistance. PLoS One 2012, 7(6):e39812.
    • (2012) PLoS One , vol.7 , Issue.6
    • Singh, A.1    Yadav, V.2    Prasad, R.3
  • 130
    • 84872963322 scopus 로고    scopus 로고
    • Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus
    • Zhao C., Mao J., Ai J., Shenwu M., Shi T., Zhang D., Wang X., Wang Y., Deng Y. Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus. BMC Med. Genomics 2013, 6(Suppl. 1):S12.
    • (2013) BMC Med. Genomics , vol.6
    • Zhao, C.1    Mao, J.2    Ai, J.3    Shenwu, M.4    Shi, T.5    Zhang, D.6    Wang, X.7    Wang, Y.8    Deng, Y.9
  • 139
    • 84881312419 scopus 로고    scopus 로고
    • Gene-diet interactions in complex disease: current findings and relevance for public health
    • Qi L. Gene-diet interactions in complex disease: current findings and relevance for public health. Curr. Nutr. Rep. 2012, 1(4):222-227.
    • (2012) Curr. Nutr. Rep. , vol.1 , Issue.4 , pp. 222-227
    • Qi, L.1
  • 140
    • 67349134667 scopus 로고    scopus 로고
    • Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach
    • Zivkovic A.M., Wiest M.M., Nguyen U., Nording M.L., Watkins S.M., German J.B. Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach. Metabolomics 2009, 5(2):209-218.
    • (2009) Metabolomics , vol.5 , Issue.2 , pp. 209-218
    • Zivkovic, A.M.1    Wiest, M.M.2    Nguyen, U.3    Nording, M.L.4    Watkins, S.M.5    German, J.B.6
  • 143
    • 84868383278 scopus 로고    scopus 로고
    • Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography-mass spectrometry profiles of complex plant extracts using multi-way decomposition methods
    • Khakimov B., Amigo J.M., Bak S., Engelsen S.B. Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography-mass spectrometry profiles of complex plant extracts using multi-way decomposition methods. J. Chromatogr. A 2012, 1266:84-94.
    • (2012) J. Chromatogr. A , vol.1266 , pp. 84-94
    • Khakimov, B.1    Amigo, J.M.2    Bak, S.3    Engelsen, S.B.4
  • 144
    • 84939885420 scopus 로고    scopus 로고
    • Chemometric evaluation of Saccharomyces cerevisiae metabolic profiles using LC-MS
    • Farrés M., Piña B., Tauler R. Chemometric evaluation of Saccharomyces cerevisiae metabolic profiles using LC-MS. Metabolomics 2015, 11(1):210-224.
    • (2015) Metabolomics , vol.11 , Issue.1 , pp. 210-224
    • Farrés, M.1    Piña, B.2    Tauler, R.3
  • 145
    • 84905265304 scopus 로고    scopus 로고
    • A non-target chemometric strategy applied to UPLC-MS sphingolipid analysis of a cell line exposed to chlorpyrifos pesticide: a feasibility study
    • Lima K.M.G., Bedia C., Tauler R. A non-target chemometric strategy applied to UPLC-MS sphingolipid analysis of a cell line exposed to chlorpyrifos pesticide: a feasibility study. Microchem. J. 2014, 117:255-261.
    • (2014) Microchem. J. , vol.117 , pp. 255-261
    • Lima, K.M.G.1    Bedia, C.2    Tauler, R.3


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