Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells

Journal of the American Chemical Society

Volumn 137, Issue 50, 2015, Pages 15892-15898

  Soto Cerrato, Vanessa ^a   Manuel Manresa, Pilar ^a   Hernando, Elsa ^b   Calabuig Fariñas, Silvia ^c,h   Martínez Romero, Alicia ^d   Fernández Dueñas, Víctor ^a   Sahlholm, Kristoffer ^a,f   Knöpfel, Thomas ^g   García Valverde, María ^b   Rodilla, Ananda M ^a   Jantus Lewintre, Eloisa ^c,i   Farràs, Rosa ^d   Ciruela, Francisco ^a,e   Pérez Tomás, Ricardo ^a   Quesada, Roberto ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF BURGOS   (Spain)

^c HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^d CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^e GHENT UNIVERSITY   (Belgium)

^f KAROLINSKA INSTITUTE   (Sweden)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

^h UNIVERSITY OF VALENCIA   (Spain)

ⁱ UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELLS; DISEASES; LIPOSOMES; METABOLITES; MOLECULES; PHOSPHOLIPIDS; PLANTS (BOTANY); STEM CELLS;

BIOLOGICAL EFFECTS; CANCER STEM CELLS; CELL DIFFERENTIATION; CELLULAR FUNCTION; HYPERPOLARIZATION; PHOSPHOLIPID LIPOSOMES; PLASMA CELL MEMBRANES; TRANSMEMBRANE TRANSPORT;

CYTOLOGY;

BICARBONATE; CHLORIDE; DOXORUBICIN; EPITHELIAL CELL ADHESION MOLECULE; LIPOSOME; ANION;

A549 CELL LINE; ACIDIFICATION; ANION EXCHANGE; ANION TRANSPORT; APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL DEATH; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PH; CELL PROLIFERATION; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DOWN REGULATION; EC50; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYPERPOLARIZATION; IC50; IMMUNOFLUORESCENCE; LIPID BILAYER; LIPOPHILICITY; LUNG ADENOCARCINOMA; MEMBRANE POTENTIAL; PLASMA CELL; PROTON NUCLEAR MAGNETIC RESONANCE; UPREGULATION; CELL LINE; ION TRANSPORT; PATHOLOGY; PHYSIOLOGY;

ANIONS; APOPTOSIS; CELL DIFFERENTIATION; CELL LINE; CELL MEMBRANE; HUMANS; ION TRANSPORT; LIPOSOMES; MEMBRANE POTENTIALS; NEOPLASTIC STEM CELLS;

EID: 84952803376     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b09970     Document Type: Article

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