Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

Nature Chemistry

Volumn 6, Issue 10, 2014, Pages 885-892

  Ko, Sung Kyun ^a,b   Kim, Sung Kuk ^c   Share, Andrew ^c   Lynch, Vincent M ^c   Park, Jinhong ^a   Namkung, Wan ^a   Van Rossom, Wim ^d   Busschaert, Nathalie ^d   Gale, Philip A ^d,e   Sessler, Jonathan L ^a,c   Shin, Injae ^a  

^a Yonsei University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ANION TRANSPORT PROTEIN; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CALIX(4)PYRROLE; CALIXARENE; CASPASE; CHLORIDE; CYTOCHROME C; DIAMIDE; LIPOSOME; MOLECULAR LIBRARY; PEPTIDE CHLOROMETHYL KETONE; PORPHYRIN; PYRIDINE; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL; APOPTOSIS; CELL LINE; CHEMISTRY; DRUG EFFECTS; HCT116 CELL LINE; HELA CELL LINE; HUMAN; ION TRANSPORT; METABOLISM; MITOCHONDRION; MOLECULAR LIBRARY; RAT;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANION TRANSPORT PROTEINS; APOPTOSIS; CALIXARENES; CASPASES; CELL LINE; CHLORIDES; CYTOCHROMES C; DIAMIDE; HCT116 CELLS; HELA CELLS; HUMANS; ION TRANSPORT; LIPOSOMES; MITOCHONDRIA; PORPHYRINS; PYRIDINES; RATS; REACTIVE OXYGEN SPECIES; SMALL MOLECULE LIBRARIES;

EID: 84911215387     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.2021     Document Type: Article

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