Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo

Matrix Biology

Volumn 50, Issue , 2016, Pages 67-81

  Keire, Paul A ^a,b   Bressler, Steven L ^a   Mulvihill, Eileen R ^b   Starcher, Barry C ^c   Kang, Inkyung ^a   Wight, Thomas N ^a,b  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

Author keywords

Elastin; Elastogenesis; Extracellular matrix; Proliferation; SiRNA; Versican

Indexed keywords

ELASTIN; MESSENGER RNA; SMALL INTERFERING RNA; TROPOELASTIN; VERSICAN; CSPG2 PROTEIN, MOUSE; VCAN PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DOWN REGULATION; ELASTIC FIBER; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEIOMYOSARCOMA; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RNA ANALYSIS; SMOOTH MUSCLE FIBER; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; CELL LINE; ELASTIC TISSUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY;

ANIMALS; CELL LINE; ELASTIC TISSUE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; IN VITRO TECHNIQUES; LEIOMYOSARCOMA; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; RNA, SMALL INTERFERING; TROPOELASTIN; VERSICANS;

EID: 84952700864     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2015.12.010     Document Type: Article

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