Retrovirally Mediated Overexpression of Versican V3 Reverses Impaired Elastogenesis and Heightened Proliferation Exhibited by Fibroblasts from Costello Syndrome and Hurler Disease Patients

American Journal of Pathology

Volumn 164, Issue 1, 2004, Pages 119-131

  Hinek, Aleksander ^a,b   Braun, Kathy R ^c   Liu, Kela ^a   Wang, Yanting ^a   Wight, Thomas N ^c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOPE HEART INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CHONDROITIN SULFATE; COMPLEMENTARY DNA; DERMATAN SULFATE; ELASTIN; ELASTIN BINDING PROTEIN; RETROVIRUS VECTOR; TROPOELASTIN; UNCLASSIFIED DRUG; VERSICAN; VERSICAN V3; CELL SURFACE RECEPTOR; CSPG2 PROTEIN, HUMAN; ELASTIN BINDING PROTEINS; ELASTIN-BINDING PROTEINS; LECTIN; MESSENGER RNA; PROTEOCHONDROITIN SULFATE;

ARTICLE; CELL PROLIFERATION; CELL SURFACE; CLINICAL ARTICLE; COSTELLO SYNDROME; ELASTIC FIBER; FEMALE; FIBROBLAST; GENE OVEREXPRESSION; GENE TRANSFER; GM1 GANGLIOSIDOSIS; HUMAN; HUMAN TISSUE; HURLER SYNDROME; MALE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; SKIN FIBROBLAST; SMOOTH MUSCLE FIBER; ANIMAL; CELL CULTURE; CELL DIVISION; ELASTIC TISSUE; GENETIC TRANSDUCTION; GENETICS; IMMUNOHISTOCHEMISTRY; INFANT; METABOLISM; NORTHERN BLOTTING; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RETROVIRUS; UPREGULATION;

ANIMALS; BLOTTING, NORTHERN; CELL DIVISION; CELLS, CULTURED; CHILD, PRESCHOOL; CHONDROITIN SULFATES; ELASTIC TISSUE; FEMALE; FIBROBLASTS; GANGLIOSIDOSIS, GM1; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; LECTINS, C-TYPE; MALE; MUCOPOLYSACCHARIDOSIS I; PROTEOCHONDROITIN SULFATES; RECEPTORS, CELL SURFACE; RETROVIRIDAE; RNA, MESSENGER; TRANSDUCTION, GENETIC; UP-REGULATION; VERSICANS;

EID: 1542469610     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63103-3     Document Type: Article

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