MMP-12, an old enzyme plays a new role in the pathogenesis of rheumatoid arthritis?

American Journal of Pathology

Volumn 165, Issue 4, 2004, Pages 1069-1070

  Chen, Yuqing E ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGENASE 3; ENAMELYSIN; ENZYME; FIBRONECTIN; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; LAMININ; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 15; MATRIX METALLOPROTEINASE 16; MATRIX METALLOPROTEINASE 17; MATRIX METALLOPROTEINASE 19; MATRIX METALLOPROTEINASE 24; MATRIX METALLOPROTEINASE 25; MATRIX METALLOPROTEINASE 4; MATRIX METALLOPROTEINASE 5; MATRIX METALLOPROTEINASE 6; METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; PROTEINASE; PROTEOGLYCAN; SCLEROPROTEIN; STROMELYSIN; STROMELYSIN 2; STROMELYSIN 3; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTHRITIS; BONE ATROPHY; CARTILAGE DEGENERATION; CHROMOSOMAL LOCALIZATION; CHROMOSOME 11Q; CHRONIC INFLAMMATION; CONNECTIVE TISSUE; DISEASE SEVERITY; ENZYME RELEASE; EXTRACELLULAR MATRIX; INFLAMMATION; JOINT DESTRUCTION; KNOCKOUT MOUSE; NOTE; OUTCOMES RESEARCH; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVITIS; TENDON LESION; TRANSGENIC ANIMAL;

EID: 4644373979     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63368-8     Document Type: Note

References (14)

1. Brinckerhoff CE, Matrisian LM, Mengshol JA, Mix KS, Vincenti MP, Clark IM; Matrix metalloproteinases: a tail of a frog that became a prince. Nat Rev Mol Cell Biol 2002, 3:207-214
2. Martel-Pelletier J, Welsch DJ, Pelletier JP: Metalloproteases and inhibitors in arthritic diseases. Best Pract Res Clin Rheumatol 2001, 15:805-829
3. Itoh T, Matsuda H, Tanioka M, Kuwabara K, Itohara S, Suzuki R: The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis. J Immunol 2002, 169:2643-2647
4. Werb Z, Gordon S: Elastase secretion by stimulated macrophages: characterization and regulation. J Exp Med 1975, 142:361-377
5. Banda MJ, Werb Z: Mouse macrophage elastase: purification and characterization as a metalloproteinase. Biochem J 1981, 193:589-605
6. Shapiro SD, Griffin GL, Gilbert DJ, Jenkins NA, Copeland NG, Welgus HG, Senior RM, Ley TJ: Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. J Biol Chem 1992, 267:4664-4671
7. Shapiro SD, Kobayashi DK, Ley TJ: Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem 1993, 268:23824-23829
8. Curci JA, Liao S, Huffman MD, Shapiro SD, Thompson RW: Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. J Clin Invest 1998,102:1900-1910
9. Matsumoto S, Kobayashi T, Katoh M, Saito S, Ikeda Y, Kobori M, Masuho Y, Watanabe T: Expression and localization of matrix metalloproteinase-12 in the aorta of cholesterol-fed rabbits: relationship to lesion development. Am J Pathol 1998, 153:109-119
10. Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD: Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997, 277:2002-2004
11. Tsuboi H, Matsui Y, Hayashida K, Yamane S, Maeda-Tanimura M, Nampei A, Hashimoto J, Suzuki R, Yoshikawa H, Ochi T: Tartrate-resistant acid phosphatase (TRAP)-positive cells in rheumatoid synovium may induce the destruction of articular cartilage. Ann Rheum Dis 2003, 62:196-203
12. Wang X, Liang J, Ichikawa T, Koike T, Shikama H, Sasaguri Y, Watanabe T, Fan J: Overexpression of matrix metalloproteinase-12 enhances experimentally inflammatory arthritis in transgenic rabbits. Am J Pathol 2004, 165:1375-1383
13. Feinberg MW, Jain MK, Werner F, Sibinga NE, Wiesel P, Wang H, Topper JN, Perrella MA, Lee ME: Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages. J Biol Chem 2000, 275:25766-25773
14. Borkakoti N: Matrix metalloprotease inhibitors: design from structure. Biochem Soc Trans 2004, 32:17-20