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Volumn 393, Issue , 2015, Pages 45-63

Molecular mechanisms of B cell antigen gathering and endocytosis

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIGEN; B LYMPHOCYTE RECEPTOR; CXCL13 CHEMOKINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; RAB7 PROTEIN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 2; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84952308482     PISSN: 0070217X     EISSN: 21969965     Source Type: Book Series    
DOI: 10.1007/82_2015_476     Document Type: Article
Times cited : (34)

References (100)
  • 1
    • 0030992644 scopus 로고    scopus 로고
    • Acceleration of intracellular targeting of antigen by the B-cell antigen receptor: Importance depends on the nature of the antigen-antibody interaction
    • Aluvihare VR, Khamlichi AA, Williams GT et al (1997) Acceleration of intracellular targeting of antigen by the B-cell antigen receptor: importance depends on the nature of the antigen-antibody interaction. EMBO J 16: 3553-3562.
    • (1997) EMBO J , vol.16 , pp. 3553-3562
    • Aluvihare, V.R.1    Khamlichi, A.A.2    Williams, G.T.3
  • 2
    • 84255195050 scopus 로고    scopus 로고
    • Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways
    • Anitei M, Hoflack B (2012) Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways. Nat Cell Biol 14: 11-19.
    • (2012) Nat Cell Biol , vol.14 , pp. 11-19
    • Anitei, M.1    Hoflack, B.2
  • 3
    • 37849000098 scopus 로고    scopus 로고
    • Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation
    • Arana E, Vehlow A, Harwood NE et al (2008) Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation. Immunity 28: 88-99.
    • (2008) Immunity , vol.28 , pp. 88-99
    • Arana, E.1    Vehlow, A.2    Harwood, N.E.3
  • 4
    • 0035942781 scopus 로고    scopus 로고
    • B cells acquire antigen from target cells after synapse formation
    • Batista FD, Iber D, Neuberger MS (2001) B cells acquire antigen from target cells after synapse formation. Nature 411: 489-494.
    • (2001) Nature , vol.411 , pp. 489-494
    • Batista, F.D.1    Iber, D.2    Neuberger, M.S.3
  • 5
    • 80053132181 scopus 로고    scopus 로고
    • WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity
    • Becker-Herman S, Meyer-Bahlburg A, Schwartz MA et al (2011) WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity. J Exp Med 208: 2033-2042.
    • (2011) J Exp Med , vol.208 , pp. 2033-2042
    • Becker-Herman, S.1    Meyer-Bahlburg, A.2    Schwartz, M.A.3
  • 6
    • 83755183062 scopus 로고    scopus 로고
    • Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization
    • Bonazzi M, Vasudevan L, Mallet A et al (2011) Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization. J Cell Biol 195: 525-536.
    • (2011) J Cell Biol , vol.195 , pp. 525-536
    • Bonazzi, M.1    Vasudevan, L.2    Mallet, A.3
  • 7
    • 80052432601 scopus 로고    scopus 로고
    • Actin dynamics counteract membrane tension during clathrin-mediated endocytosis
    • Boulant S, Kural C, Zeeh J-C et al (2011) Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol 13: 1124-1131.
    • (2011) Nat Cell Biol , vol.13 , pp. 1124-1131
    • Boulant, S.1    Kural, C.2    Zeeh, J.-C.3
  • 8
    • 84952347994 scopus 로고    scopus 로고
    • Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity
    • Burbage M, Keppler SJ, Gasparrini F et al (2014) Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity. J Exp Med 369: 113.
    • (2014) J Exp Med , vol.369 , pp. 113
    • Burbage, M.1    Keppler, S.J.2    Gasparrini, F.3
  • 9
    • 84872764090 scopus 로고    scopus 로고
    • Cis and trans regulatory mechanisms control AP2-mediated B cell receptor endocytosis via select tyrosine-based motifs
    • Busman-Sahay K, Drake L, Sitaram A et al (2013) Cis and trans regulatory mechanisms control AP2-mediated B cell receptor endocytosis via select tyrosine-based motifs. PLoS ONE 8: e54938.
    • (2013) PLoS ONE , vol.8
    • Busman-Sahay, K.1    Drake, L.2    Sitaram, A.3
  • 10
    • 33845591357 scopus 로고    scopus 로고
    • Functional and structural requirements for the internalization of distinct BCR-ligand complexes
    • Caballero A, Katkere B, Wen X-Y et al (2006) Functional and structural requirements for the internalization of distinct BCR-ligand complexes. Eur J Immunol 36: 3131-3145.
    • (2006) Eur J Immunol , vol.36 , pp. 3131-3145
    • Caballero, A.1    Katkere, B.2    Wen, X.-Y.3
  • 11
    • 33746545207 scopus 로고    scopus 로고
    • B cell recognition of membrane-bound antigen: An exquisite way of sensing ligands
    • Carrasco YR, Batista FD (2006a) B cell recognition of membrane-bound antigen: an exquisite way of sensing ligands. Curr Opin Immunol 18: 286-291.
    • (2006) Curr Opin Immunol , vol.18 , pp. 286-291
    • Carrasco, Y.R.1    Batista, F.D.2
  • 12
    • 33644542737 scopus 로고    scopus 로고
    • B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1
    • Carrasco YR, Batista FDA (2006b) B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1. EMBO J 25: 889-899.
    • (2006) EMBO J , vol.25 , pp. 889-899
    • Carrasco, Y.R.1    Batista, F.D.A.2
  • 13
    • 34447623566 scopus 로고    scopus 로고
    • B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node
    • Carrasco YR, Batista FD (2007) B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. Immunity 27: 160-171.
    • (2007) Immunity , vol.27 , pp. 160-171
    • Carrasco, Y.R.1    Batista, F.D.2
  • 14
    • 2442467885 scopus 로고    scopus 로고
    • LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation
    • Carrasco YR, Fleire SJ, Cameron T et al (2004) LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation. Immunity 20: 589-599.
    • (2004) Immunity , vol.20 , pp. 589-599
    • Carrasco, Y.R.1    Fleire, S.J.2    Cameron, T.3
  • 15
    • 84857871473 scopus 로고    scopus 로고
    • Modulation of antigen presentation and B cell receptor signaling in B cells of beige mice
    • Chatterjee P, Tiwari RK, Rath S et al (2012) Modulation of antigen presentation and B cell receptor signaling in B cells of beige mice. J Immunol 188: 2695-2702.
    • (2012) J Immunol , vol.188 , pp. 2695-2702
    • Chatterjee, P.1    Tiwari, R.K.2    Rath, S.3
  • 16
    • 44649161194 scopus 로고    scopus 로고
    • The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyper-responses to DNA-containing antigens
    • Chaturvedi A, Dorward D, Pierce SK (2008) The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyper-responses to DNA-containing antigens. Immunity 28: 799-809.
    • (2008) Immunity , vol.28 , pp. 799-809
    • Chaturvedi, A.1    Dorward, D.2    Pierce, S.K.3
  • 17
    • 80054928885 scopus 로고    scopus 로고
    • Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments
    • Chaturvedi A, Martz R, Dorward D et al (2011) Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments. Nat Immunol 12: 1119-1126.
    • (2011) Nat Immunol , vol.12 , pp. 1119-1126
    • Chaturvedi, A.1    Martz, R.2    Dorward, D.3
  • 18
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • Cinamon G, Zachariah MA, Lam OM et al (2008) Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol 9: 54-62.
    • (2008) Nat Immunol , vol.9 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3
  • 19
    • 0028176660 scopus 로고
    • Analysis of Ig-α-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-α stimulation of Fyn activity
    • Clark MR, Johnson SA, Cambier JC (1994) Analysis of Ig-α-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-α stimulation of Fyn activity. EMBO J 13: 1911-1919.
    • (1994) EMBO J , vol.13 , pp. 1911-1919
    • Clark, M.R.1    Johnson, S.A.2    Cambier, J.C.3
  • 20
    • 84864634144 scopus 로고    scopus 로고
    • The first five seconds in the life of a Clathrin-coated pit
    • Cocucci E, Aguet F, Boulant S, Kirchhausen T (2012) The first five seconds in the life of a Clathrin-coated pit. Cell 150: 495-507.
    • (2012) Cell , vol.150 , pp. 495-507
    • Cocucci, E.1    Aguet, F.2    Boulant, S.3    Kirchhausen, T.4
  • 21
    • 77958126430 scopus 로고    scopus 로고
    • B cell follicles and antigen encounters of the third kind
    • Cyster JG (2010) B cell follicles and antigen encounters of the third kind. Nat Immunol 11: 989.
    • (2010) Nat Immunol , vol.11 , pp. 989
    • Cyster, J.G.1
  • 22
    • 73849145729 scopus 로고    scopus 로고
    • Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
    • Davis RE, Ngo VN, Lenz G et al (2010) Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature 463: 88-92.
    • (2010) Nature , vol.463 , pp. 88-92
    • Davis, R.E.1    Ngo, V.N.2    Lenz, G.3
  • 23
    • 37349077033 scopus 로고    scopus 로고
    • CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand
    • Depoil D, Fleire S, Treanor BL et al (2008) CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand. Nat Immunol 9: 63-72.
    • (2008) Nat Immunol , vol.9 , pp. 63-72
    • Depoil, D.1    Fleire, S.2    Treanor, B.L.3
  • 25
    • 0035126502 scopus 로고    scopus 로고
    • Epstein-barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR
    • Dykstra ML, Longnecker R, Pierce SK (2001) Epstein-barr virus coopts lipid rafts to block the signaling and antigen transport functions of the BCR. Immunity 14: 57-67.
    • (2001) Immunity , vol.14 , pp. 57-67
    • Dykstra, M.L.1    Longnecker, R.2    Pierce, S.K.3
  • 26
    • 4444224966 scopus 로고    scopus 로고
    • Endocytosis by random initiation and stabilization of clathrin-coated pits
    • Ehrlich M, Boll W, Van Oijen A et al (2004) Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell 118: 591-605.
    • (2004) Cell , vol.118 , pp. 591-605
    • Ehrlich, M.1    Boll, W.2    Van Oijen, A.3
  • 27
    • 0033611051 scopus 로고    scopus 로고
    • An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles
    • Engqvist-Goldstein ÅEY, Kessels MM, Chopra VS et al (1999) An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles. J Cell Biol 147: 1503-1518.
    • (1999) J Cell Biol , vol.147 , pp. 1503-1518
    • Engqvist-Goldstein, Å.E.Y.1    Kessels, M.M.2    Chopra, V.S.3
  • 28
    • 5044252309 scopus 로고    scopus 로고
    • Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells
    • Ferguson AR, Youd ME, Corley RB (2004) Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int Immunol 16: 1411-1422.
    • (2004) Int Immunol , vol.16 , pp. 1411-1422
    • Ferguson, A.R.1    Youd, M.E.2    Corley, R.B.3
  • 29
    • 71649086146 scopus 로고    scopus 로고
    • Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits
    • Ferguson SM, Raimondi A, Paradise S et al (2009) Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell 17: 811-822.
    • (2009) Dev Cell , vol.17 , pp. 811-822
    • Ferguson, S.M.1    Raimondi, A.2    Paradise, S.3
  • 30
    • 33646454106 scopus 로고    scopus 로고
    • B cell ligand discrimination through a spreading and contraction response
    • Fleire SJ, Goldman JP, Carrasco YR et al (2006) B cell ligand discrimination through a spreading and contraction response. Science 312: 738-741.
    • (2006) Science , vol.312 , pp. 738-741
    • Fleire, S.J.1    Goldman, J.P.2    Carrasco, Y.R.3
  • 31
    • 82755189245 scopus 로고    scopus 로고
    • Cofilin-mediated F-actin severing is regulated by the rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation
    • Freeman SA, Lei V, Dang-Lawson M et al (2011) Cofilin-mediated F-actin severing is regulated by the rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol 187: 5887-5900.
    • (2011) J Immunol , vol.187 , pp. 5887-5900
    • Freeman, S.A.1    Lei, V.2    Dang-Lawson, M.3
  • 32
    • 84860241876 scopus 로고    scopus 로고
    • Novel functions of murine B1 cells: Active phagocytic and microbicidal abilities
    • Gao J, Ma X, Gu W et al (2012) Novel functions of murine B1 cells: active phagocytic and microbicidal abilities. Eur J Immunol 42: 982-992.
    • (2012) Eur J Immunol , vol.42 , pp. 982-992
    • Gao, J.1    Ma, X.2    Gu, W.3
  • 33
    • 33745863907 scopus 로고    scopus 로고
    • Ig β tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization
    • Gazumyan A, Reichlin A, Nussenzweig MC (2006) Ig β tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization. J Exp Med 203: 1785-1794.
    • (2006) J Exp Med , vol.203 , pp. 1785-1794
    • Gazumyan, A.1    Reichlin, A.2    Nussenzweig, M.C.3
  • 34
    • 77951298265 scopus 로고    scopus 로고
    • Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes
    • Gonzalez SF, Lukacs-Kornek V, Kuligowski MP et al (2010) Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat Immunol 11: 427-434.
    • (2010) Nat Immunol , vol.11 , pp. 427-434
    • Gonzalez, S.F.1    Lukacs-Kornek, V.2    Kuligowski, M.P.3
  • 35
    • 84901986407 scopus 로고    scopus 로고
    • The role of the cytoskeleton and molecular motors in endosomal dynamics
    • Granger E, McNee G, Allan V, Woodman P (2014) The role of the cytoskeleton and molecular motors in endosomal dynamics. Semin Cell Dev Biol 31: 20-29.
    • (2014) Semin Cell Dev Biol , vol.31 , pp. 20-29
    • Granger, E.1    McNee, G.2    Allan, V.3    Woodman, P.4
  • 36
    • 0033605563 scopus 로고    scopus 로고
    • Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-γ1 signaling pathway
    • Haugh JM, Schooler K, Wells A et al (1999) Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-γ1 signaling pathway. J Biol Chem 274: 8958-8965.
    • (1999) J Biol Chem , vol.274 , pp. 8958-8965
    • Haugh, J.M.1    Schooler, K.2    Wells, A.3
  • 37
    • 84879606860 scopus 로고    scopus 로고
    • Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation
    • Heesters BA, Chatterjee P, Kim Y-A et al (2013) Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation. Immunity 38: 1164-1175.
    • (2013) Immunity , vol.38 , pp. 1164-1175
    • Heesters, B.A.1    Chatterjee, P.2    Kim, Y.-A.3
  • 38
    • 33745924969 scopus 로고    scopus 로고
    • B cell antigen receptor signaling and internalization are mutually exclusive events
    • Hou P, Araujo E, Zhao T et al (2006) B cell antigen receptor signaling and internalization are mutually exclusive events. PLoS Biol 4: e200.
    • (2006) PLoS Biol , vol.4
    • Hou, P.1    Araujo, E.2    Zhao, T.3
  • 39
    • 19444383222 scopus 로고    scopus 로고
    • Dephosphorylation and internalization of cell adhesion molecule L1 induced by theta burst stimulation in rat hippocampus
    • Itoh K, Shimono K, Lemmon V (2005) Dephosphorylation and internalization of cell adhesion molecule L1 induced by theta burst stimulation in rat hippocampus. Mol Cell Neurosci 29: 245-249.
    • (2005) Mol Cell Neurosci , vol.29 , pp. 245-249
    • Itoh, K.1    Shimono, K.2    Lemmon, V.3
  • 40
    • 77953884976 scopus 로고    scopus 로고
    • A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex
    • Jackson LP, Kelly BT, McCoy AJ et al (2010) A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex. Cell 141: 1220-1229.
    • (2010) Cell , vol.141 , pp. 1220-1229
    • Jackson, L.P.1    Kelly, B.T.2    McCoy, A.J.3
  • 41
    • 78049318830 scopus 로고    scopus 로고
    • The role of Ig-α/β in B cell antigen receptor internalization
    • Jang C, Machtaler S, Matsuuchi L (2010) The role of Ig-α/β in B cell antigen receptor internalization. Immunol Lett 134: 75-82.
    • (2010) Immunol Lett , vol.134 , pp. 75-82
    • Jang, C.1    Machtaler, S.2    Matsuuchi, L.3
  • 42
    • 84862728987 scopus 로고    scopus 로고
    • Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling
    • Jean S, Cox S, Schmidt EJ et al (2012) Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. Mol Biol Cell 23: 2723-2740.
    • (2012) Mol Biol Cell , vol.23 , pp. 2723-2740
    • Jean, S.1    Cox, S.2    Schmidt, E.J.3
  • 43
    • 35948935059 scopus 로고    scopus 로고
    • Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
    • Junt T, Moseman EA, Iannacone M et al (2007) Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 450: 110-114.
    • (2007) Nature , vol.450 , pp. 110-114
    • Junt, T.1    Moseman, E.A.2    Iannacone, M.3
  • 44
    • 84860864074 scopus 로고    scopus 로고
    • The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation
    • Katkere B, Rosa S, Drake JR (2012) The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation. J Biol Chem 287: 16636-16644.
    • (2012) J Biol Chem , vol.287 , pp. 16636-16644
    • Katkere, B.1    Rosa, S.2    Drake, J.R.3
  • 45
    • 84923846462 scopus 로고    scopus 로고
    • Rab proteins implicated in lipid storage and mobilization
    • Kiss RS, Nilsson T (2014) Rab proteins implicated in lipid storage and mobilization. J Biomed Res 28: 169-177.
    • (2014) J Biomed Res , vol.28 , pp. 169-177
    • Kiss, R.S.1    Nilsson, T.2
  • 46
    • 34248512113 scopus 로고    scopus 로고
    • Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b
    • Kitaura Y, Jang IK, Wang Y et al (2007) Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b. Immunity 26: 567-578.
    • (2007) Immunity , vol.26 , pp. 567-578
    • Kitaura, Y.1    Jang, I.K.2    Wang, Y.3
  • 47
    • 33748875713 scopus 로고    scopus 로고
    • B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities
    • Li J, Barreda DR, Zhang Y-A et al (2006) B lymphocytes from early vertebrates have potent phagocytic and microbicidal abilities. Nat Immunol 7: 1116-1124.
    • (2006) Nat Immunol , vol.7 , pp. 1116-1124
    • Li, J.1    Barreda, D.R.2    Zhang, Y.-A.3
  • 48
    • 37849031433 scopus 로고    scopus 로고
    • The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands
    • Lin KBL, Freeman SA, Zabetian S et al (2008) The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands. Immunity 28: 75-87.
    • (2008) Immunity , vol.28 , pp. 75-87
    • Lin, K.B.L.1    Freeman, S.A.2    Zabetian, S.3
  • 49
    • 78650753565 scopus 로고    scopus 로고
    • Local clustering of transferrin receptors promotes clathrin-coated pit initiation
    • Liu AP, Aguet F, Danuser G, Schmid SL (2010) Local clustering of transferrin receptors promotes clathrin-coated pit initiation. J Cell Biol 191: 1381-1393.
    • (2010) J Cell Biol , vol.191 , pp. 1381-1393
    • Liu, A.P.1    Aguet, F.2    Danuser, G.3    Schmid, S.L.4
  • 50
    • 84889025677 scopus 로고    scopus 로고
    • N-WASP is essential for the negative regulation of B cell receptor signaling
    • Liu C, Bai X, Wu J et al (2013) N-WASP is essential for the negative regulation of B cell receptor signaling. PLoS Biol 11: e1001704.
    • (2013) PLoS Biol , vol.11
    • Liu, C.1    Bai, X.2    Wu, J.3
  • 51
    • 0035253720 scopus 로고    scopus 로고
    • Visualization of Syk-antigen receptor interactions using green fluorescent protein: Differential roles for Syk and Lyn in the regulation of receptor capping and internalization
    • Ma H, Yankee TM, Hu J et al (2001) Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization. J Immunol 166: 1507-1516.
    • (2001) J Immunol , vol.166 , pp. 1507-1516
    • Ma, H.1    Yankee, T.M.2    Hu, J.3
  • 52
    • 73649113139 scopus 로고    scopus 로고
    • Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB
    • Malhotra S, Kovats S, Zhang W, Coggeshall KM (2009) Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB. J Biol Chem 284: 36202-36212.
    • (2009) J Biol Chem , vol.284 , pp. 36202-36212
    • Malhotra, S.1    Kovats, S.2    Zhang, W.3    Coggeshall, K.M.4
  • 53
    • 0035013708 scopus 로고    scopus 로고
    • Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens
    • Martin F, Oliver AM, Kearney JF (2001) Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14: 617-629.
    • (2001) Immunity , vol.14 , pp. 617-629
    • Martin, F.1    Oliver, A.M.2    Kearney, J.F.3
  • 54
    • 67651229135 scopus 로고    scopus 로고
    • Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways
    • Matsumoto M, Oyamada K, Takahashi H et al (2009) Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways. Proteomics 9: 3549-3563.
    • (2009) Proteomics , vol.9 , pp. 3549-3563
    • Matsumoto, M.1    Oyamada, K.2    Takahashi, H.3
  • 56
    • 0032582646 scopus 로고    scopus 로고
    • Activation of the Rap1 GTPase by the B cell antigen receptor
    • McLeod SJ, Ingham RJ, Bos JL et al (1998) Activation of the Rap1 GTPase by the B cell antigen receptor. J Biol Chem 273: 29218-29223.
    • (1998) J Biol Chem , vol.273 , pp. 29218-29223
    • McLeod, S.J.1    Ingham, R.J.2    Bos, J.L.3
  • 57
    • 1642417606 scopus 로고    scopus 로고
    • APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment
    • Miaczynska M, Christoforidis S, Giner A et al (2004) APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell 116: 445-456.
    • (2004) Cell , vol.116 , pp. 445-456
    • Miaczynska, M.1    Christoforidis, S.2    Giner, A.3
  • 58
    • 84866152172 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
    • Minden MD-V, Übelhart R, Schneider D et al (2013) Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling. Nature 489: 309-312.
    • (2013) Nature , vol.489 , pp. 309-312
    • Minden, M.D.-V.1    Übelhart, R.2    Schneider, D.3
  • 59
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks C, Freiberg B, Kupfer H et al (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395: 82-86.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.1    Freiberg, B.2    Kupfer, H.3
  • 60
    • 84879694222 scopus 로고    scopus 로고
    • B cells use mechanical energy to discriminate antigen affinities
    • Natkanski E, Lee W-Y, Mistry B et al (2013) B cells use mechanical energy to discriminate antigen affinities. Science 340: 1587-1590.
    • (2013) Science , vol.340 , pp. 1587-1590
    • Natkanski, E.1    Lee, W.-Y.2    Mistry, B.3
  • 61
    • 79551686422 scopus 로고    scopus 로고
    • Oncogenically active MYD88 mutations in human lymphoma
    • Ngo VN, Young RM, Schmitz R et al (2012) Oncogenically active MYD88 mutations in human lymphoma. Nature 469: 115-119.
    • (2012) Nature , vol.469 , pp. 115-119
    • Ngo, V.N.1    Young, R.M.2    Schmitz, R.3
  • 62
    • 6344274704 scopus 로고    scopus 로고
    • The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization
    • Niiro H, Allam A, Stoddart A et al (2004) The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization. J Immunol 173: 5601-5609.
    • (2004) J Immunol , vol.173 , pp. 5601-5609
    • Niiro, H.1    Allam, A.2    Stoddart, A.3
  • 63
    • 45549095846 scopus 로고    scopus 로고
    • Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation
    • Onabajo OO, Seeley MK, Kale A et al (2008) Actin-binding protein 1 regulates B cell receptor-mediated antigen processing and presentation in response to B cell receptor activation. J Immunol 180: 6685-6695.
    • (2008) J Immunol , vol.180 , pp. 6685-6695
    • Onabajo, O.O.1    Seeley, M.K.2    Kale, A.3
  • 64
    • 65549136622 scopus 로고    scopus 로고
    • Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells
    • O'Neill S, Veselits M, Zhang M et al (2009) Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells. PNAS 106: 6262-6267.
    • (2009) PNAS , vol.106 , pp. 6262-6267
    • O'Neill, S.1    Veselits, M.2    Zhang, M.3
  • 65
    • 81955161811 scopus 로고    scopus 로고
    • Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy
    • O'Neill SK, Getahun A, Gauld SB et al (2011) Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy. Immunity 35: 746-756.
    • (2011) Immunity , vol.35 , pp. 746-756
    • O'Neill, S.K.1    Getahun, A.2    Gauld, S.B.3
  • 66
    • 34247149876 scopus 로고    scopus 로고
    • The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles
    • Pape KA, Catron DM, Itano AA, Jenkins MK (2007) The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity 26: 491-502.
    • (2007) Immunity , vol.26 , pp. 491-502
    • Pape, K.A.1    Catron, D.M.2    Itano, A.A.3    Jenkins, M.K.4
  • 67
    • 84874284008 scopus 로고    scopus 로고
    • Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin
    • Parameswaran N, Enyindah-Asonye G, Bagheri N et al (2013) Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin. J Immunol 190: 2017-2026.
    • (2013) J Immunol , vol.190 , pp. 2017-2026
    • Parameswaran, N.1    Enyindah-Asonye, G.2    Bagheri, N.3
  • 68
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • Phan TG, Grigorova I, Okada T, Cyster JG (2007) Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol 8: 992-1000.
    • (2007) Nat Immunol , vol.8 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 69
    • 80755132190 scopus 로고    scopus 로고
    • Endosomal transport via ubiquitination
    • Piper RC, Lehner PJ (2011) Endosomal transport via ubiquitination. Trends Cell Biol 21: 647-655.
    • (2011) Trends Cell Biol , vol.21 , pp. 647-655
    • Piper, R.C.1    Lehner, P.J.2
  • 70
    • 84885458867 scopus 로고    scopus 로고
    • Ezrin tunes the magnitude of humoral immunity
    • Pore D, Pore D, Parameswaran N et al (2013) Ezrin tunes the magnitude of humoral immunity. J Immunol 191: 4048-4058.
    • (2013) J Immunol , vol.191 , pp. 4048-4058
    • Pore, D.1    Pore, D.2    Parameswaran, N.3
  • 71
    • 84880507763 scopus 로고    scopus 로고
    • Spatiotemporal control of endocytosis by phosphatidylinositol-3, 4-bisphosphate
    • Posor Y, Eichhorn-Gruenig M, Puchkov D et al (2013) Spatiotemporal control of endocytosis by phosphatidylinositol-3, 4-bisphosphate. Nature 499: 233-237.
    • (2013) Nature , vol.499 , pp. 233-237
    • Posor, Y.1    Eichhorn-Gruenig, M.2    Puchkov, D.3
  • 72
    • 84855962862 scopus 로고    scopus 로고
    • B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
    • Puga I, Cols M, Barra CM et al (2012) B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nat Immunol 13: 170-180.
    • (2012) Nat Immunol , vol.13 , pp. 170-180
    • Puga, I.1    Cols, M.2    Barra, C.M.3
  • 73
    • 33745133006 scopus 로고    scopus 로고
    • Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells
    • Qi H, Egen JG, Huang AYC, Germain RN (2006) Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 312: 1672-1676.
    • (2006) Science , vol.312 , pp. 1672-1676
    • Qi, H.1    Egen, J.G.2    Huang, A.Y.C.3    Germain, R.N.4
  • 74
    • 70449718702 scopus 로고    scopus 로고
    • Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
    • Randall KL, Lambe T, Johnson A et al (2009) Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production. Nat Immunol 10: 1283-1291.
    • (2009) Nat Immunol , vol.10 , pp. 1283-1291
    • Randall, K.L.1    Lambe, T.2    Johnson, A.3
  • 75
    • 60149086845 scopus 로고    scopus 로고
    • Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
    • Roozendaal R, Mempel TR, Pitcher LA et al (2009) Conduits mediate transport of low-molecular-weight antigen to lymph node follicles. Immunity 30: 264-276.
    • (2009) Immunity , vol.30 , pp. 264-276
    • Roozendaal, R.1    Mempel, T.R.2    Pitcher, L.A.3
  • 76
    • 84883391753 scopus 로고    scopus 로고
    • Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse
    • Saez de Guinoa J, Barrio L, Carrasco YR (2013) Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse. J Immunol 191: 2742-2751.
    • (2013) J Immunol , vol.191 , pp. 2742-2751
    • Saez de Guinoa, J.1    Barrio, L.2    Carrasco, Y.R.3
  • 77
    • 80051630207 scopus 로고    scopus 로고
    • CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics
    • Sáez de Guinoa J, Barrio L, Mellado M, Carrasco YR (2011) CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics. Blood 118: 1560-1569.
    • (2011) Blood , vol.118 , pp. 1560-1569
    • Sáez de Guinoa, J.1    Barrio, L.2    Mellado, M.3    Carrasco, Y.R.4
  • 78
    • 84934295586 scopus 로고    scopus 로고
    • Systems-wide analysis of the BCR signaling complexes and the downstream phosphorylation and ubiquitylation
    • Satpathy S, Wagner SA, Beli P, et al (2015) Systems-wide analysis of the BCR signaling complexes and the downstream phosphorylation and ubiquitylation. Mol Syst Biol 11: 810.
    • (2015) Mol Syst Biol , vol.11 , pp. 810
    • Satpathy, S.1    Wagner, S.A.2    Beli, P.3
  • 79
    • 79959371732 scopus 로고    scopus 로고
    • B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3to recruit dynein to the signaling microcluster
    • Schnyder T, Castello A, Feest C et al (2011) B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3to recruit dynein to the signaling microcluster. Immunity 34: 905-918.
    • (2011) Immunity , vol.34 , pp. 905-918
    • Schnyder, T.1    Castello, A.2    Feest, C.3
  • 80
    • 79958255209 scopus 로고    scopus 로고
    • A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center
    • Schwickert TA, Victora GD, Fooksman DR et al (2011) A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med 208: 1243-1252.
    • (2011) J Exp Med , vol.208 , pp. 1243-1252
    • Schwickert, T.A.1    Victora, G.D.2    Fooksman, D.R.3
  • 81
    • 84903954497 scopus 로고    scopus 로고
    • Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways
    • Seeley-Fallen MK, Liu LJ, Shapiro MR et al (2014) Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways. PNAS 111: 9881-9886.
    • (2014) PNAS , vol.111 , pp. 9881-9886
    • Seeley-Fallen, M.K.1    Liu, L.J.2    Shapiro, M.R.3
  • 82
    • 59849093193 scopus 로고    scopus 로고
    • Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells
    • Sharma S, Orlowski G, Song W (2009) Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells. J Immunol 182: 329-339.
    • (2009) J Immunol , vol.182 , pp. 329-339
    • Sharma, S.1    Orlowski, G.2    Song, W.3
  • 83
    • 0036073140 scopus 로고    scopus 로고
    • Role of BCR affinity in T cell dependent antibody responses in vivo
    • Shih T-AY, Meffre E, Roederer M, Nussenzweig MC (2002) Role of BCR affinity in T cell dependent antibody responses in vivo. Nat Immunol 3: 570-575.
    • (2002) Nat Immunol , vol.3 , pp. 570-575
    • Shih, T.-A.Y.1    Meffre, E.2    Roederer, M.3    Nussenzweig, M.C.4
  • 84
    • 23944437499 scopus 로고    scopus 로고
    • An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
    • Shin H-W, Hayashi M, Christoforidis S et al (2005) An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol 170: 607-618.
    • (2005) J Cell Biol , vol.170 , pp. 607-618
    • Shin, H.-W.1    Hayashi, M.2    Christoforidis, S.3
  • 85
    • 0037944241 scopus 로고    scopus 로고
    • Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk
    • Sohn HW, Gu H, Pierce SK (2003) Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk. J Exp Med 197: 1511-1524.
    • (2003) J Exp Med , vol.197 , pp. 1511-1524
    • Sohn, H.W.1    Gu, H.2    Pierce, S.K.3
  • 86
    • 84885344283 scopus 로고    scopus 로고
    • Actin-mediated feedback loops in B-cell receptor signaling
    • Song W, Liu C, Seeley-Fallen MK et al (2013) Actin-mediated feedback loops in B-cell receptor signaling. Immunol Rev 256: 177-189.
    • (2013) Immunol Rev , vol.256 , pp. 177-189
    • Song, W.1    Liu, C.2    Seeley-Fallen, M.K.3
  • 87
    • 67649223631 scopus 로고    scopus 로고
    • B cell receptor-mediated internalization of salmonella: A novel pathway for autonomous B cell activation and antibody production
    • Souwer Y, Griekspoor A, Jorritsma T et al (2009) B cell receptor-mediated internalization of salmonella: a novel pathway for autonomous B cell activation and antibody production. J Immunol 182: 7473-7481.
    • (2009) J Immunol , vol.182 , pp. 7473-7481
    • Souwer, Y.1    Griekspoor, A.2    Jorritsma, T.3
  • 88
    • 0036800489 scopus 로고    scopus 로고
    • Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization
    • Stoddart A, Dykstra ML, Brown BK et al (2002) Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization. Immunity 17: 451-462.
    • (2002) Immunity , vol.17 , pp. 451-462
    • Stoddart, A.1    Dykstra, M.L.2    Brown, B.K.3
  • 89
    • 18244406506 scopus 로고    scopus 로고
    • Plasticity of B cell receptor internalization upon conditional depletion of clathrin
    • Stoddart A, Jackson AP, Brodsky F (2005) Plasticity of B cell receptor internalization upon conditional depletion of clathrin. Mol Biol Cell 16: 2339-2348.
    • (2005) Mol Biol Cell , vol.16 , pp. 2339-2348
    • Stoddart, A.1    Jackson, A.P.2    Brodsky, F.3
  • 90
    • 67650482967 scopus 로고    scopus 로고
    • Visualizing B cell capture of cognate antigen from follicular dendritic cells
    • Suzuki K, Grigorova I, Phan TG et al (2009) Visualizing B cell capture of cognate antigen from follicular dendritic cells. J Exp Med 206: 1485-1493.
    • (2009) J Exp Med , vol.206 , pp. 1485-1493
    • Suzuki, K.1    Grigorova, I.2    Phan, T.G.3
  • 91
    • 84859416334 scopus 로고    scopus 로고
    • The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane
    • Tanno H, Yamaguchi T, Goto E et al (2012) The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane. Mol Biol Cell 23: 1343-1353.
    • (2012) Mol Biol Cell , vol.23 , pp. 1343-1353
    • Tanno, H.1    Yamaguchi, T.2    Goto, E.3
  • 92
    • 84900803443 scopus 로고    scopus 로고
    • Force generation in B-cell synapses: Mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination
    • Tolar P, Spillane KM (2014) Force generation in B-cell synapses: mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination. Adv Immunol 123: 69-100.
    • (2014) Adv Immunol , vol.123 , pp. 69-100
    • Tolar, P.1    Spillane, K.M.2
  • 93
    • 58149247765 scopus 로고    scopus 로고
    • The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens
    • Tolar P, Hanna J, Krueger PD, Pierce SK (2009) The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens. Immunity 30: 44-55.
    • (2009) Immunity , vol.30 , pp. 44-55
    • Tolar, P.1    Hanna, J.2    Krueger, P.D.3    Pierce, S.K.4
  • 94
    • 79956106702 scopus 로고    scopus 로고
    • Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity
    • Treanor B, Depoil D, Bruckbauer A, Batista FD (2011) Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity. J Exp Med 208: 1055-1068.
    • (2011) J Exp Med , vol.208 , pp. 1055-1068
    • Treanor, B.1    Depoil, D.2    Bruckbauer, A.3    Batista, F.D.4
  • 95
    • 84923565805 scopus 로고    scopus 로고
    • Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to toll-like receptor 9 activation in late endosomes
    • Veselits M, Tanaka A, Lipkowitz S et al (2014) Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to toll-like receptor 9 activation in late endosomes. PLoS ONE 9: e89792.
    • (2014) PLoS ONE , vol.9
    • Veselits, M.1    Tanaka, A.2    Lipkowitz, S.3
  • 96
    • 78149477766 scopus 로고    scopus 로고
    • Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
    • Victora GD, Schwickert TA, Fooksman DR et al (2010) Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143: 592-605.
    • (2010) Cell , vol.143 , pp. 592-605
    • Victora, G.D.1    Schwickert, T.A.2    Fooksman, D.R.3
  • 97
    • 42249090333 scopus 로고    scopus 로고
    • Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen
    • Weber M, Treanor B, Depoil D et al (2008) Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen. J Exp Med 205: 853-868.
    • (2008) J Exp Med , vol.205 , pp. 853-868
    • Weber, M.1    Treanor, B.2    Depoil, D.3
  • 98
    • 80053130049 scopus 로고    scopus 로고
    • Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation
    • Yuseff M-I, Reversat A, Lankar D et al (2011) Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation. Immunity 35: 361-374.
    • (2011) Immunity , vol.35 , pp. 361-374
    • Yuseff, M.-I.1    Reversat, A.2    Lankar, D.3
  • 99
    • 59849085748 scopus 로고    scopus 로고
    • Ubiquitinylation of Igβ dictates the endocytic fate of the B cell antigen receptor
    • Zhang M, Veselits M, O'Neill S et al (2007) Ubiquitinylation of Igβ dictates the endocytic fate of the B cell antigen receptor. J Immunol 179: 4435-4443.
    • (2007) J Immunol , vol.179 , pp. 4435-4443
    • Zhang, M.1    Veselits, M.2    O'Neill, S.3
  • 100
    • 62549151303 scopus 로고    scopus 로고
    • A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes
    • Zoncu R, Perera RM, Balkin DM et al (2009) A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell 136: 1110-1121.
    • (2009) Cell , vol.136 , pp. 1110-1121
    • Zoncu, R.1    Perera, R.M.2    Balkin, D.M.3


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