Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk

Journal of Experimental Medicine

Volumn 197, Issue 11, 2003, Pages 1511-1524

  Sohn, Hae Won ^a   Gu, Hua ^a   Pierce, Susan K ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Antigen receptor; B cells; Capping; Tyrosine kinase; Ubiquitination

Indexed keywords

B LYMPHOCYTE ANTIGEN; B LYMPHOCYTE ANTIGEN RECEPTOR; CD69 ANTIGEN; IMMUNOGLOBULIN A; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA2; PROTEIN; PROTEIN CBL B; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CALCIUM MOBILIZATION; CHEMICAL MODIFICATION; CONTROLLED STUDY; CROSS LINKING; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; B-LYMPHOCYTES; CALCIUM SIGNALING; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CROSS-LINKING REAGENTS; ENZYME PRECURSORS; IMMUNOGLOBULIN ALPHA-CHAINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTOR AGGREGATION; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 0037944241     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021686     Document Type: Article

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