Modulation of antigen presentation and B cell receptor signaling in B cells of beige mice

Journal of Immunology

Volumn 188, Issue 6, 2012, Pages 2695-2702

  Chatterjee, Priyadarshini ^a,b   Tiwari, Ritesh Kumar ^a   Rath, Satyajit ^a   Bal, Vineeta ^a   George, Anna ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW; CROSS LINKING; ENDOCYTOSIS; HELPER CELL; HUMORAL IMMUNITY; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; LYSOSOME; MEMORY CELL; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN PRESENTATION; B-LYMPHOCYTES; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SEPARATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; LYMPHOCYTE ACTIVATION; LYSOSOMES; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84857871473     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101527     Document Type: Article

References (43)

1. Lanzavecchia, A. 1985. Antigen-specific interaction between T and B cells. Nature 314: 537-539. (Pubitemid 15124262)
2. Poovassery, J. S., T. J. Vanden Bush, and G. A. Bishop. 2009. Antigen receptor signals rescue B cells from TLR tolerance. J. Immunol. 183: 2974-2983.
3. Zhang, H., S. Rosenberg, F. J. Coffey, Y. W. He, T. Manser, R. R. Hardy, and J. Zhang. 2009. A role for cFLIP in B cell proliferation and stress MAPK regulation. J. Immunol. 182: 207-215.
4. Cheng, P. C., M. L. Dykstra, R. N. Mitchell, and S. K. Pierce. 1999. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting. J. Exp. Med. 190: 1549-1560. (Pubitemid 30002337)
5. Kurosaki, T. 1999. Genetic analysis of B cell antigen receptor signaling. Annu. Rev. Immunol. 17: 555-592. (Pubitemid 29241134)
6. Campbell, K. S. 1999. Signal transduction from the B cell antigen-receptor. Curr. Opin. Immunol. 11: 256-264. (Pubitemid 29263952)
7. Stoddart, A., M. L. Dykstra, B. K. Brown, W. Song, S. K. Pierce, and F. M. Brodsky. 2002. Lipid rafts unite signaling cascades with clathrin to regulate BCR internalization. Immunity 17: 451-462. (Pubitemid 35223534)
8. Niiro, H., A. Allam, A. Stoddart, F. M. Brodsky, A. J. Marshall, and E. A. Clark. 2004. The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization. J. Immunol. 173: 5601-5609. (Pubitemid 39392147)
9. Lanzavecchia, A. 1990. Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu. Rev. Immunol. 8: 773-793. (Pubitemid 20135646)
10. Lankar, D., H. Vincent-Schneider, V. Briken, T. Yokozeki, G. Raposo, and C. Bonnerot. 2002. Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation. J. Exp. Med. 195: 461-472. (Pubitemid 34461299)
11. Siemasko, K., and M. R. Clark. 2001. The control and facilitation of MHC class II antigen processing by the BCR. Curr. Opin. Immunol. 13: 32-36. (Pubitemid 32096957)
12. Schmid, D., M. Pypaert, and C. Münz. 2007. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity 26: 79-92. (Pubitemid 46109341)
13. Chaturvedi, A., D. Dorward, and S. K. Pierce. 2008. The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity 28: 799-809.
14. McHeyzer-Williams, L. J., N. Pelletier, L. Mark, N. Fazilleau, and M. G. McHeyzer-Williams. 2009. Follicular helper T cells as cognate regulators of B cell immunity. Curr. Opin. Immunol. 21: 266-273.
15. Raman, V. S., R. S. Akondy, S. Rath, V. Bal, and A. George. 2003. Ligation of CD27 on B cells in vivo during primary immunization enhances commitment to memory B cell responses. J. Immunol. 171: 5876-5881. (Pubitemid 37467204)
16. Mukherjee, P., A. Dani, S. Bhatia, N. Singh, A. Y. Rudensky, A. George, V. Bal, S. Mayor, and S. Rath. 2001. Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis. J. Immunol. 167: 2632-2641. (Pubitemid 32768892)
17. Sinnathamby, G., and L. C. Eisenlohr. 2003. Presentation by recycling MHC class II molecules of an influenza hemagglutinin-derived epitope that is revealed in the early endosome by acidification. J. Immunol. 170: 3504-3513. (Pubitemid 36359216)
18. Garside, P., E. Ingulli, R. R. Merica, J. G. Johnson, R. J. Noelle, and M. K. Jenkins. 1998. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 281: 96-99. (Pubitemid 28354051)
19. Jacob, J., R. Kassir, and G. Kelsoe. 1991. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173: 1165-1175.
20. Liu, Y. J., J. Zhang, P. J. Lane, E. Y. Chan, and I. C. MacLennan. 1991. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21: 2951-2962.
21. Klein, U., and R. Dalla-Favera. 2008. Germinal centres: role in B-cell physiology and malignancy. Nat. Rev. Immunol. 8: 22-33.
22. Wagner, S. D., and M. S. Neuberger. 1996. Somatic hypermutation of immunoglobulin genes. Annu. Rev. Immunol. 14: 441-457. (Pubitemid 26130657)
23. Shokat, K. M., and C. C. Goodnow. 1995. Antigen-induced B-cell death and elimination during germinal-centre immune responses. Nature 375: 334-338.
24. Tew, J. G., R. P. Phipps, and T. E. Mandel. 1980. The maintenance and regulation of the humoral immune response: persisting antigen and the role of follicular antigen-binding dendritic cells as accessory cells. Immunol. Rev. 53: 175-201. (Pubitemid 11119138)
25. Batista, F. D., and M. S. Neuberger. 1998. Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate. Immunity 8: 751-759. (Pubitemid 28294522)
26. Liu, Y. J., F. Malisan, O. de Bouteiller, C. Guret, S. Lebecque, J. Banchereau, F. C. Mills, E. E. Max, and H. Martinez-Valdez. 1996. Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity 4: 241-250. (Pubitemid 26131007)
27. George, A., and J. J. Cebra. 1991. Responses of single germinal-center B cells in T-cell-dependent microculture. Proc. Natl. Acad. Sci. USA 88: 11-15. (Pubitemid 21914415)
28. Perou, C. M., J. D. Leslie, W. Green, L. Li, D. M. Ward, and J. Kaplan. 1997. The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein. J. Biol. Chem. 272: 29790-29794. (Pubitemid 27508075)
29. Cornillon, S., A. Dubois, F. Brückert, Y. Lefkir, A. Marchetti, M. Benghezal, A. De Lozanne, F. Letourneur, and P. Cosson. 2002. Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. J. Cell Sci. 115: 737-744. (Pubitemid 34196333)
30. Zhang, H., X. Fan, R. D. Bagshaw, L. Zhang, D. J. Mahuran, and J. W. Callahan. 2007. Lysosomal membranes from beige mice contain higher than normal levels of endoplasmic reticulum proteins. J. Proteome Res. 6: 240-249. (Pubitemid 46173676)
31. Spritz, R. A. 1998. Genetic defects in Chediak-Higashi syndrome and the beige mouse. J. Clin. Immunol. 18: 97-105. (Pubitemid 28120176)
32. Ward, D. M., G. M. Griffiths, J. C. Stinchcombe, and J. Kaplan. 2000. Analysis of the lysosomal storage disease Chediak-Higashi syndrome. Traffic 1: 816-822.
33. Oliver, C., and E. Essner. 1975. Formation of anomalous lysosomes in monocytes, neutrophils, and eosinophils from bone marrow of mice with Chédiak-Higashi syndrome. Lab. Invest. 32: 17-27.
34. Bahadoran, P., E. Aberdam, F. Mantoux, R. Buscà, K. Bille, N. Yalman, G. de Saint-Basile, R. Casaroli-Marano, J. P. Ortonne, and R. Ballotti. 2001. Rab27a: A key to melanosome transport in human melanocytes. J. Cell Biol. 152: 843-850.
35. Paigen, B., P. A. Holmes, E. K. Novak, and R. T. Swank. 1990. Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function. Arteriosclerosis 10: 648-652. (Pubitemid 20220589)
36. Baca, M. E., A. M. Mowat, and D. M. Parrott. 1989. Immunological studies of NK cell-deficient beige mice. II. Analysis of T-lymphocyte functions in beige mice. Immunology 66: 131-137. (Pubitemid 19041619)
37. Klein, M., J. Roder, T. Haliotis, S. Korec, J. R. Jett, R. B. Herberman, P. Katz, and A. S. Fauci. 1980. Chédiak-Higashi gene in humans. II. The selectivity of the defect in natural-killer and antibody-dependent cell-mediated cytotoxicity function. J. Exp. Med. 151: 1049-1058. (Pubitemid 10111921)
38. Biron, C. A., K. F. Pedersen, and R. M. Welsh. 1987. Aberrant T cells in beige mutant mice. J. Immunol. 138: 2050-2056. (Pubitemid 17046250)
39. Stinchcombe, J. C., L. J. Page, and G. M. Griffiths. 2000. Secretory lysosome biogenesis in cytotoxic T lymphocytes from normal and Chediak Higashi syndrome patients. Traffic 1: 435-444.
40. Takeuchi, K., H. Wood, and R. T. Swank. 1986. Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G. J. Exp. Med. 163: 665-677. (Pubitemid 16141969)
41. Haliotis, T., J. Roder, M. Klein, J. Ortaldo, A. S. Fauci, and R. B. Herberman. 1980. Chédiak-Higashi gene in humans I. Impairment of natural-killer function. J. Exp. Med. 151: 1039-1048. (Pubitemid 10111920)
42. Faigle, W., G. Raposo, D. Tenza, V. Pinet, A. B. Vogt, H. Kropshofer, A. Fischer, G. de Saint-Basile, and S. Amigorena. 1998. Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome. J. Cell Biol. 141: 1121-1134. (Pubitemid 28265607)
43. Schwickert, T. A., G. D. Victora, D. R. Fooksman, A. O. Kamphorst, M. R. Mugnier, A. D. Gitlin, M. L. Dustin, and M. C. Nussenzweig. (2011). A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J. Exp. Med. 208: 1243-1252.