A comprehensive analysis of radiosensitization targets; Functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Fujimori, Hiroaki ^a   Sato, Akira ^a   Kikuhara, Sota ^a,b   Wang, Junhui ^a,c   Hirai, Takahisa ^a,d   Sasaki, Yuka ^a   Murakami, Yasufumi ^b   Okayasu, Ryuichi ^e   Masutani, Mitsuko ^a,f  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^f NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3B; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; HISTONE; NONHISTONE PROTEIN; PROTEIN BINDING; SMALL INTERFERING RNA;

ANIMAL; CELL CYCLE CHECKPOINT; CELL SURVIVAL; CLUSTER ANALYSIS; DISEASE MODEL; DNA DAMAGE; DNA METHYLATION; DRUG SCREENING; GAMMA RADIATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE SILENCING; GENETICS; HELA CELL LINE; HUMAN; MALE; METABOLISM; MOUSE; NEOPLASMS; PATHOLOGY; RADIATION RESPONSE; RADIATION TOLERANCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMOSOMAL PROTEINS, NON-HISTONE; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA DAMAGE; DNA METHYLATION; GAMMA RAYS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; HELA CELLS; HISTONES; HUMANS; MALE; MICE; NEOPLASMS; PROTEIN BINDING; RADIATION TOLERANCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84950132200     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18231     Document Type: Article

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