Potentials of some plant-derived foods in the management of diabetes and associated complications

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 12, Issue 6, 2015, Pages 12-20

  Ogunyinka, Bolajoko Idiat ^a   Oyinloye, Babatunji Emmanuel ^a,b   Adenowo, Abiola Fatimah ^a   Kappo, Abidemi Paul ^a  

^a UNIVERSITY OF ZULULAND   (South Africa)

^b AFE BABALOLA UNIVERSITY   (Nigeria)

Author keywords

Antioxidants; Diabetes; Diabetic complications; Hyperglycemia; Nutraceuticals; Plant foods

Indexed keywords

ALPHA GLUCOSIDASE; AMYLASE; CARICA PAPAYA EXTRACT; CINNAMOMUM VERUM EXTRACT; CURCUMA LONGA EXTRACT; GARCINA KOLA EXTRACT; GARLIC EXTRACT; GINGER EXTRACT; MANGNIFERA INDICA EXTRACT; OCIMUM GRATISSIMUM EXTRACT; PARKIA BIGLOBOSA EXTRACT; PIPER GUINEENSE EXTRACT; PLANT EXTRACT; TELFAIRIA OCCIDENTALIS EXTRACT; TETRACARPIDIUM CONOPHORUM EXTRACT; UNCLASSIFIED DRUG; VERNONIA AMYGDALINA EXTRACT;

ANACARDIACEAE; ANALGESIC ACTIVITY; ANTIBACTERIAL ACTIVITY; ANTICARCINOGENIC ACTIVITY; ANTIDIABETIC ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPARASITIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CINNAMOMUM ZEYLANICUM; DIABETES MELLITUS; DIETARY INTAKE; DISEASE ASSOCIATION; DRUG ACTIVITY; ENZYME INHIBITION; GARCINA KOLA; GLYCEMIC INDEX; HUMAN; HYPERGLYCEMIA; HYPOCHOLESTEROLEMIA; HYPOGLYCEMIA; HYPOLIPEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN SENSITIVITY; LIFESTYLE MODIFICATION; MANGNIFERA INDICA; NONHUMAN; PARKIA BIGLOBOSA; PATHOGENESIS; PIPER (PLANT); PIPER GUINEENSE; PLANT LEAF; RISK FACTOR; TELFAIRIA OCCIDENTALIS; TETRACARPIDIUM CONOPHORUM;

EID: 84950128168     PISSN: None     EISSN: 01896016     Source Type: Journal    
DOI: 10.4314/ajtcam.v12i6.2     Document Type: Article

References (88)

1. Abam, E.O., Oladipo, F.Y., Atasie, V.N. and Obayomi, A.A. (2013). Effect of Walnut (Tetracarpidium conophorum)-oil on Cadmium-Induced Alterations in Lipid Metabolism in Male Albino Rats. Food. Publ. Health., 3(4): 169–175.
2. Adaramoye, O.A. and Adeyemi, E.O. (2006). Hypoglycaemic and hypolipidaemic effects of fractions from kolaviron, a biflavonoid complex from Garcinia Kola in streptozotocin-induced diabetes mellitus rats. J. Pharm. Pharmacol. 58: 121–128.
3. Adaramoye, O.A., Akintayo, O., Achem, J. and Fafunso, M.A. (2008). Lipid-lowering effects of methanolic extract of Vernonia amygdalina leaves in rats fed on high cholesterol diet. Vasc. Health. Risk. Manag., 4(1): 235–241.
4. Aderibigbe, A.O., Emudianughe, T.S. and Lawal, B.S. (2001). Evaluation of the antidiabetic action of Mangifera indica in mice. Phytother. Res., 15(5): 456–458.
5. Adi, K., Metowogo, K., Mouzou, A., Lawson-Evi, P., Eklu-Gadegbeku, K., Agbonon, A., Lamboni, C., Essien, K., Aklikokou, K. and Gbeassor, M. (2013). Evaluation of cardioprotective effects of Parkia biglobosa (jacq. benth) Mimosaceae stem bark. J. App. Pharm. Sci., 3(2): 60–64.
6. Al-Amin, Z.M., Thomson, M., Al-Qattan, K.K., Peltonen-Shalaby, R. and Ali, M. (2006). Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br. J. Nutr. 96: 660–666.
7. American Diabetes Association. (2014). Diagnosis and classification of diabetes mellitus. Diabetes. Care., 37: S81–S90.
8. Anderson, R.A. (2008). Chromium and polyphenols from cinnamon improve insulin sensitivity. Proc. Nutr. Soc., 67(01): 48–53.
9. Atkinson, M.A. (2012). The pathogenesis and natural history of type 1 diabetes. Cold. Spring. Harb. Perspect. Med., 2: a007641.
10. Bahadoran, Z., Mirmiran, P., & Azizi, F. (2013). Dietary polyphenols as potential nutraceuticals in management of diabetes: a review. J Diabetes Metab Disord, 12(1), 43.
11. Blackburn, D.F., Swidrovich, J. and Lemstra, M. (2013). Non-adherence in type 2 diabetes: practical considerations for interpreting the literature. Patient. Prefer. Adherence., 7: 183–189.
12. Borek, C. (2001). Antioxidant health effects of aged garlic extract. J. Nutr., 131(3): 1010S–1015S.
13. Brunetti, L. and Kalabalik, J. (2012). Management of type-2 diabetes mellitus in adults: focus on individualizing non-insulin therapies. P. T., 37(12): 687.
14. Cade, W.T. (2008). Diabetes-related microvascular and macrovascular diseases in the physical therapy setting. Phys. Ther., 88(11): 1322–1335.
15. Cao, H., Graves, D.J. and Anderson, R.A. (2010). Cinnamon extracts regulate glucose transporter and insulin signaling gene expression in mouse adipocyte. Phytomedicine., 17(13): 1027–1032.
16. Chattopadhyay, I., Biswas, K., Bandyopadhyay, U., Ranajit, K. and Banerjee, R.K. (2004). Turmeric and curcumin: Biological actions and medicinal applications. Curr. Sci., 87(1): 44–53.
17. Chawla, R., Thakur, P., Chowdhry, A., Jaiswal, S., Sharma, A., Goel, R., Sharma, J., Priyadarshi, S.S., Kumar, V. and Sharma, R.K. (2013). Evidence based herbal drug standardization approach in coping with challenges of holistic management of diabetes: a dreadful lifestyle disorder of 21st century. J. Diabetes. Metab. Disord., 12: 35.
18. Collard, E. and Roy, S. (2010). Improved function of diabetic wound-site macrophages and accelerated wound closure in response to oral supplementation of a fermented papaya preparation. Antioxid. Redox. Signal., 13(5): 599–606.
19. Cooke, D.W. and Plotnick, L. (2008). Type 1 diabetes mellitus in pediatrics. Pediatr. Rev., 29: 374–385.
20. Corzo-Martínez, M., Corzo, N. and Villamiel, M. (2007). Biological properties of onions and garlic. Trends. Food. Sci. Technol., 18(12): 609–625.
21. Davi, G., Santilli, F. and Patrono, C. (2010). Nutraceuticals in diabetes and metabolic syndrome. Cardiovasc. Ther., 28(4): 216–226.
22. Eidi, A., Eidi, M. and Esmaeili, E. (2006). Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine., 13(9): 624–629.
23. Ekoh, S.N., Akubugwo, E.I., Ude, V.U. and Edwin, N. (2014). Anti-hyperglycemic and anti-hyperlipidemic effect of spices (Thymus vulgaris, Murraya koenigii, Ocimum gratissimum and Piper guineense) in alloxan- induced diabetic rats. Int. J. Biosci., 4(2): 179–187.
24. El-Masry, A.A. (2012). Potential Therapeutic Effect of Curcuma longa on Streptozotocin Induced Diabetic rats. Global. Adv. Res. J. Med. Med. Sci., 1(4): 91–98.
25. Folli, F., Corradi, D., Fanti, P., Davalli, A., Paez, A., Giaccari, A., Perego, C. and Muscogiuri, G. (2011). The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro-and macrovascular complications: avenues for a mechanistic-based therapeutic approach. Curr. Diabetes. Rev., 7(5): 313–324.
26. Fred-Jaiyesimi, A.A. and Abo, K.A. (2009). Hypoglycaemic effects of Parkia biglobosa (Jacq) Benth seed extract in glucose-loaded and NIDDM rats. Int. J. Biol. Chem. Sci., 3(3): 545-550.
27. Giacco, F. and Brownlee, M. (2010). Oxidative stress and diabetic complications. Circ. Res. 107(9): 1058–1070.
28. Hemmerle, H., Burger, H.J., Below, P., Schubert, G., Rippel, R., Schindler, P.W., Paulus, E. and Herling, A.W. (1997). Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase. J. Med. Chem., 40(2): 137–45.
29. Hu, F.B. (2011). Globalization of Diabetes The role of diet, lifestyle, and genes. Diabetes. Care., 34(6): 1249–1257
30. Ikpesu, T.O., Tongo, I. and Ariyo, A. (2014) Restorative Prospective of Powdered Seeds Extract of Garcinia kola in Chrysichthys furcatus Induced with Glyphosate Formulation. Chin. J. Biol., 2014: 854157.
31. International Diabetes Federation. (2011). Global Diabetes Plan 2011–2021. Belgium: International Diabetes Federation. http://www.idf.org. Accessed 8 July 2014.
32. Inzucchi, S.E., Bergenstal, R.M., Buse, J.B., Diamant, M., Ferrannini, E., Nauck, M., Peters, A.L., Tsapas, A., Wender, R. and Matthews, D.R. (2012). Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia., 55(6): 1577–1596.
33. Irons, B.K. and Minze, M.G. (2014). Drug treatment of type 2 diabetes mellitus in patients for whom metformin is contraindicated. Diabetes. Metab. Syndr. Obes. Targets. Ther., 7: 15–24.
34. Jaganjac, M., Tirosh, O., Cohen, G., Sasson, S. and Zarkovic, N. (2013) Reactive aldehydes-second messengers of free radicals in diabetes mellitus. Free. Radical. Res., 47(S1): 39–48.
35. Johansen, J.S., Harris, A.K., Rychly, D.J. and Ergul, A. (2005). Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc. Diabetol., 4(1): 5.
36. Johnston, K.L., Clifford, M.N. and Morgan, L.M. (2003). Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am. J. Clin. Nutr. 78(4): 728–33.
37. Joseph, B. and Jini, D. (2011). Insight into the hypoglycaemic effect of traditional Indian herbs used in the treatment of diabetes. Res. J. Med. Plant., 5(4): 352–376.
38. Juárez-Rojop, I.E., Díaz-Zagoya, J.C., Ble-Castillo, J.L., Miranda-Osorio, P.H., Castell-Rodríguez, A.E., Tovilla-Zárate, C.A., Rodríguez- Hernández, A., Aguilar-Mariscal, H., Ramón-Frías, T. and Bermúdez-Ocaña, D.Y. (2012). Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats. BCM. Complement. Altern. Med., 12: 236.
39. Kayode, A.A.A. and Kayode, O.T. (2011). Some medicinal values of Telfairia occidentalis: A review. Am. J. Biochem. Mol. Biol., 1: 30–38.
40. Khan, V., Najmi, A.K., Akhtar, M., Aqil, M., Mujeeb, M. and Pillai, K.K. (2012). A pharmacological appraisal of medicinal plants with antidiabetic potential. J. Pharm. Bioallied. Sci., 4(1): 27.
41. Kharkar, R., Pawar, D.P. and Shamkuwar, P.P. (2013). Anti-diabetic activity of Sphaeranthus indicus Linn. Extracts in Alloxan induced diabetic rats. Int. J. Pharm. Pharm. Sci., 5(2): 524–526.
42. Krishna, K.L., Paridhavi, M. and Patel, J.A. (2008). Review on nutritional, medicinal and pharmacological properties of papaya (Carica papaya Linn.). Nat. Prod. Radiance. 7(4): 364–373.
43. Krishnaswamy, K. (2008). Traditional Indian spices and their health significance. Asia. Pac. J. Clin. Nutr. 17(S1): 265–268.
44. Kuroda, M., Mimaki, Y., Nishiyama, T., Mae, T., Kishida, H., Tsukagawa, M., Takahashi, K., Kawada, T., Nakagawa, K. and Kitahara, M. (2005). Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice. Biol. Pharm. Bull., 28(5): 937–939.
45. Li, Y., Tran, V.H., Duke, C.C. and Roufogalis, B.D. (2012). Preventive and protective prop-erties of Zingiber officinale (ginger) in diabetes mellitus, diabetic complications, and associated lipid and other metabolic disorders: a brief review. Evid. Based. Complement. Alternat. Med., 2012: 516870.
46. Lima, M.L., Cruz, T., Pousada, J.C., Rodrigues, L.E., Barbosa, K. and Cangucu, V. (1998). The effect of magnesium supplementation in increasing doses on the control of type 2 diabetes. Diabetes. Care., 21(5): 682–686.
47. Lin, Y. and Sun, Z. (2010). Current views on type 2 diabetes. J. Endocrinol., 204: 1–11.
48. Maebashi, M., Makino, Y., Furukawa, Y., Ohinata, K., Kimura, S. and Sato, T. (1993) Therapeutic evaluation of the effect of biotin on hyperglycemia in patients with non-insulin dependent diabetes mellitus. J. Clin. Biochem. Nutr., 14(3): 211–218.
49. Marotta, F., Weksler, M., Naito, Y., Yoshida, C., Yoshioka, M. and Marandola, P. (2006). Nutraceutical supplementation: Effect of a fermented papaya preparation on redox status and DNA damage in healthy elderly individuals and relationship with GSTM1 genotype. Ann. N. Y. Acad. Sci., 1067(1): 400–407.
50. McCarty, M.F. (2005). Nutraceutical resources for diabetes prevention – an update. Med. Hypotheses., 64(1): 151–158.
51. Meece, J. (2007). Pancreatic islet dysfunction in type 2 diabetes: a rational target for incretin-based therapies. Curr. Med. Res. Opin. 23(4): 933–944.
52. Mishra, B. (2012). Status of nutraceuticals in European Union with special emphasis on botanical sources. J. Nat. Remedies., 12(2): 103–107.
53. Modak, M., Dixit, P., Londhe, J., Ghaskadbi, S. and Devasagayam T.P.A. (2007). Indian herbs and herbal drugs used for the treatment of diabetes. J. Clin. Biochem. Nutr., 40(3): 163.
54. Modak, M., Dixit, P., Londhe, J., Ghaskadbi, S., Paul, A. and Devasagayam, T. (2007) Indian herbs and herbal drugs used for the treatment of diabetes. J. Clin. Biochem. Nutr., 40(3): 163–173
55. Mohammed, A., Tanko, Y., Okasha, M.A., Magaji, R.A. and Yaro, A.H. Effects of aqueous leaves extract of Ocimum gratissimum on blood glucose levels of streptozocin induced diabeticWistar rats. Afr. J. Biotechnol., 2007; 6 (18): 2087–2090.
56. Muruganandan, S., Gupta, S., Kataria, M., Lal, J. and Gupta, P.K. (2002). Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicol., 176: 165–173.
57. Muruganandan, S., Srinivasan, K., Gupta, S., Gupta, P.K. and Lal, J. (2005). Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats. J. Ethnopharmacol., 97(3): 497–501.
58. Nammi, S., Sreemantula, S. and Roufogalis, B.D. (2009). Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. Basic. Clin. Pharmacol. Toxicol., 104:366–373.
59. Nweze, E.I. and Eze, E.E. (2009). Justification for the use of Ocimum gratissimum L in herbal medicine and its interaction with disc antibiotics. BMC. Complement. Altern. Med. 28: 9e37.
60. Nwozo, S.O., Ajagbe, A.A. and Oyinloye, B.E. (2012). Hepatoprotective effect of Piper guineense aqueous extract against ethanol- induced toxicity in male rats. J. Exp. Integr. Med., 2(1): 71–76.
61. Nwozo, S.O., Osunmadewa, D.A. and Oyinloye, B.E. (2014). Anti-fatty liver effects of oils from Zingiber officinale and Curcuma longa on ethanol-induced fatty liver in rats. J. Integr. Med., 12:59–65.
62. Oboh, F.O. and Masodje, H.I. (2009). Nutritional and antimicrobial properties of Vernonia amygdalina leaves. Int. J. Biomed. Health. Sci. 5(2): 51–57.
63. Oboh, G., Akinyemi, A.J. and Ademiluyi, A.O. (2012). Inhibition of α-amylase and α-glucosidase activities by ethanolic extract of Telfairia occidentalis (fluted pumpkin) leaf. Asian. Pac. J. Trop. Biomed., 2(9): 733–738.
64. Oboh, G., Nwanna, E.E. and Elusiyan, C.A. (2006). Antioxidant and antimicrobial properties of Telfairia occidentalis (Fluted Pumpkin) leaf extracts. J. Pharmacol. Toxicol., 1(2): 167–175.
65. Odetola, A.A., Akinloye, O., Egunjobi, C., Adekunle, W.A. and Ayoola, A.O. (2006). Possible antidiabetic and antihyperlipidaemic effect of fermented Parkia biglobosa (JACQ) extract in alloxan-induced diabetic rats. Clin. Exp. Pharmacol. Physiol. 33: 808–812.
66. Oguanobi, N.I., Chijioke, C.P. and Ghasi, S. (2012). Anti-diabetic effect of crude leaf extracts of Ocimum gratissimum in neonatal streptozotocin-induced Type-2 model diabetic rats. Int. J. Pharm. Pharm. Sci., 4(5): 77–83.
67. Olokoba, A.B., Obateru, O.A. and Olokoba, L.B. (2012). Type 2 Diabetes mellitus: a review of current trends. Oman. Med. J., 27(4): 269–273
68. Omar, E.A., Kam, A., Alqahtani, A., Li, K.M., Razmovski-Naumovski, V., Nammi, S., Chan, K., Roufogalis, B.D. and Li, G.Q. (2010). Herbal medicines and nutraceuticals for diabetic vascular complications: mechanisms of action and bioactive phytochemicals. Curr. Pharm. Des., 16(34): 3776–3807.
69. Onwuli, D.O., Brown, H. and Ozoani, H.A. (2014). Antihyperglycaemic Effect of Tetracarpidium conophorum Nuts in Alloxan Induced Diabetic Female Albino Rats. ISRN. Endocrinology., 2014: 124974.
70. Oputa, R.N. and Chinenye, S. (2012). Diabetes mellitus: a global epidemic with potential solutions. Afr. J. Diabetes. Medicine., 20(2): 33–35.
71. Pandey, N., Meena, R.P., Rai, S.K. and Pandey-Rai, S. (2011). Medicinal plants derived nutraceuticals: a re-emerging health aid. Int. J. Pharm. Biosci., 2(4): 419–441.
72. Rahman, K. (2007). Studies on free radicals, antioxidants, and co-factors. Clin. Interv. Aging., 2(2): 219.
73. Ramachandran, S., Asokkumar, K., Uma Maheswari, M., Ravi, T.K., Sivashanmugam, A.T., Saravanan, S., Rajasekaran, A. and Dharman, J. (2011). Investigation of antidiabetic, antihyperlipidemic, and in vivo antioxidant properties of Sphaeranthus indicus Linn. in type 1 diabetic rats: an identification of possible biomarkers. Evid. Based. Complement. Alternat. Med., 2011: 571721.
74. Roussel, A.M., Hininger, I., Benaraba, R., Ziegenfuss, T.N. and Anderson, R.A. (2009). Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese. J. Am. Coll. Nutr., 28(1): 16–21.
75. Rwegerera, G.M. (2014). Adherence to anti-diabetic drugs among patients with Type 2 diabetes mellitus at Muhimbili National Hospital, Dar es Salaam, Tanzania-A cross-sectional study. Pan. Afr. Med. J., 2014: 17.
76. Shah, K.A., Patel, M.B., Patel, R.J. and Parmar, P.K. (2010). Mangifera indica (Mango). Pharmacog. Rev. 4(7): 42–48.
77. Siegel, K. and Narayan, K.M.V. (2008). The Unite for Diabetes Campaign: Overcoming constraints to find a global policy solution. Global. Health., 4:3.
78. Steiner, M. and Li, W. (2001). Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions. J. Nutr., 131(3): 980S–984S.
79. Tikoo, D. and Gupta, M. (2012). Incretin mimetics: new age drugs for type 2 diabetes mellitus. Pak. J. Pharmacol. 29(2): 35–41.
80. Tiwari, B.K., Pandey, K.B., Abidi, A.B. and Rizvi, S.I. (2013). Markers of oxidative stress during diabetes mellitus. J. Biomarkers., 2013: 378790.
81. Udofia, P.G., Essien, N., Ukpe, R.A. and Robert, A.N. (2014). Proximate composition and effect of solvent on the distribution and concentration of active chemical components of Piper guineense seed using GCMS. J. Chem. Biol. Physical. Sci., 4(2): 1132–1145.
82. Umoh, I., Oyebadejo, S., Bassey, E.O. and Nnah, U. (2013). Chronic consumption of combined extracts of Abelmoschus esculentus and Piper guineense induced hepatoxicity in Wistar rats: Histopathological study. Int. J. Pharm., 4(2): 73–77.
83. Wang, Z., Wang, J. and Chan, P. (2013). Treating type 2 diabetes mellitus with traditional Chinese and Indian medicinal herbs. Evid. Based. Complement. Alternat. Med., 2013: 343594.
84. Yeap, S.K., Ho, W.Y., Beh, B.K., Liang, W.S., Ky, H., Yousr, A.H.N. and Alitheen, N.B. (2010). Vernonia amygdalina, an ethnoveterinary and ethnomedical used green vegetable with multiple bioactivities. J. Med. Plants. Res., 4(25): 2787–2812.
85. Yeh, Y.Y. and Liu, L. (2001). Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. J. Nutr., 131(3): 989S–993S.
86. Zammitt, N.N. and Frier, B.M. (2005). Hypoglycemia in Type 2 Diabetes Pathophysiology, frequency, and effects of different treatment modalities. Diabetes. Care., 28(12): 2948–2961.
87. Zhang, H., Osada, K., Maebashi, M., Ito, M., Komai, M. and Furukawa, Y. (1996). A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus. J. Nutr. Sci. Vitaminol., 42(6): 517–526.
88. Zhang, H., Osada, K., Sone, H., and Furukawa, Y. (1997). Biotin administration improves the impaired glucose tolerance of streptozotocininduced diabetic Wistar rats. J. Nutr. Sci. Vitaminol., 43(3): 271–280.