Anti-diabetic activity of Sphaeranthus indicus Linn. extracts in Alloxan-induced diabetic rats

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 5, Issue 2, 2013, Pages 524-526

  Kharkar, Ritesh ^a   Pawar, Deepak P ^b   Shamkuwar, Prashant B ^b  

^a Nagar Yuwak Shikshan Sanstha   (India)

^b Government College of Pharmacy   (India)

Author keywords

Alloxan induced diabetic rats; Antihyperglyceamic; Antiperoxidative; Lipid peroxidation; Sphaeranthus indicus

Indexed keywords

ACETIC ACID ETHYL ESTER; ALLOXAN; GLUCOSE; LIPID PEROXIDE; METHANOL; PLANT EXTRACT; SPHAERANTHUS INDICUS EXTRACT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIABETES MELLITUS; LIPID PEROXIDATION; NONHUMAN; RAT; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 84875924914     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. O'Brien RM, Granner DK, Regulation of gene expression by insulin. Physiological Reviews. 1996; 76: 1109-61.
2. King H., Aubert RE, Herman WH. Global burden of diabetes. Diabetes Care.1995: 21: 1414-31.
3. Boyle JP, Honneycutt AA, Narayan KM, Hoerger TJ, Geiss LS, Chen H, Thompson TJ. Projections of diabetes burden through 2050: impact of changing demography and disease prevalence in the US. Diabetes Care. 2001; 24: 1936-40.
4. Kesari AN, Gupta RK, Watal G. Hypoglycemic effects of Murraya koenigii on normal and alloxan diabetic rabbits. J of Ethnopharmacology. 2005; 97: 247-51.
5. Gupta RK, Kesari AN, Murthy PS, Chandra R, Tandon V, Watal G. Hypoglycemic and Antidiabetic Effect of Ethanolic Extract of Leaves of Annona squamosa L. in Experimental Animals. Journal of Ethnopharmacology. 2005; 99: 75-81
6. Gogate VM. Ayurvedic pharmacology and therapeutic uses of medicinal plants (Dravyaganvigyan), 1st ed. Mumbai: Bhartiya Vidya Bhavan; 2000.
7. Kirtikar KR, Basu BD. Indian medicinal plants. 2nd ed. Dehradun: International Book Distributors; 1987.
8. Gupta NS. The Ayurvedic system of medicine. Vol. II. New Delhi: Logas Press; 1984.
9. Paranjape P. Indian medicinal plants. In: Forgotten healer: A guide to Ayurvedic herbal medicine. Delhi: Chaukhamba Sanskrit Pratisthan; 2001. p. 148-9.
10. Baslas KK. Essential oil from Sphaeranthus indicus. Perf Ess Oil Rec 1959; 50:765.
11. Basu NK, Lamsal PP. Chemical investigation of Sphaeranthus indicus Linn. J Am Pharm Asso 1946; 35: 274-5.
12. Gupta RK, Chandra S, Mahandevan V. Chemical composition of Sphaeranthus indicus Linn. Indian J Pharm 1967; 29: 47-8.
13. Gogate MG, Ananthasubramanian L, Nargund KS, Bhattacharyya SC. Some interesting sesquiterpinoids from Sphaeranthus indicus Linn. (Compositae). Indian J Chem 1986; 25B: 233-8.
14. Shekhani MS, Shah PM, Yasmin A, Siddiqui R, Perveen S, Khan KM, et al. An immunostimulant sesquiterpene glycoside from Sphaeranthus indicus. Phytochem 1990; 29: 2573-6.
15. Yadav RN, Kumar S. 7-Hydroxy-3', 4', 5, 6-tetramethoxy flavone 7-O-b-D-(1-4)-diglucoside, a new flavone glycoside from the stem of Sphaeranthus indicus. J Inst Chem 1998; 70: 164-6.
16. Srivastav SC, Khan MSY, Vohra SB. Pharmacological and haemostatic investigation on Sphaeranthus indicus Linn. Indian J Physiol Pharmacol 1971; 15: 27-33.
17. Shaikh D, Naqui BS, Shaikh R. The antimicrobial principles of Sphaeranthus indicus: Isolation, purification and antimicrobial action. Pak J Sci Ind Res 1986; 29: 366-71.
18. Singh SK, Saroj K, Tripathi UJ, Singh AK, Singh RH. An antimicrobial principle from Sphaeranthus indicus (Fam: Compositae). Int J Crude Drug 1988; 26: 235-9.
19. Garg SC, Kasera HL. Antifungal activity of the essential oil of Sphaeranthus indicus Linn. Pafai J 1982; 4: 23-4.
20. Aruna RV, Ramesh B, Kartha VN. Effect of beta carotene on protein glysylaion in alloxan induced diabetic rats. Indian J Exp Biol 1999; 37: 399-01.
21. Latha M, Pari L. Braz. J. Med. Biol. Res 2004; 37: 579.
22. Ambade, V.N., Sharma, Y. V; and Somani, B.L., Medical Journal Armed Forces India, 1998, 54(2), 131-133.
23. Ohkawa H, Ohishi N, Yagi K, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 1979; 95: 351-58.
24. Shinde S, Chivate N, Kulkarni P, Naikwade N. Hypolipidemic activity of Psidium guajava linn leaves extracts in hyperlipidemic rats. International Journal of Pharmacy and Pharmaceutical Sciences 2013, 5 (1), 70-72.
25. Acworth IN, McCabe DR, Maber T. The analysis of free radicals, their reaction products and antioxidants. Taylor and Francis, Baskin SI., Salem H. 1997.
26. Xing FZ, Tan BW. Antihyperglycemic and antioxidant properties of Andrographis paniculata in normal and diabetic rats. Clinical and Experimental Pharmacology and Physiology 2000; 27: 358-63.
27. Hemamalini K, Pavani P. Antihyperglycemic effect of Sophorainterrupta bedd. And Gymnosporiaemarginata (willd.) in alloxan induced diabetic rats. International Journal of Pharmacy and Pharmaceutical Sciences 2013, 5 (1), 103-107.