Selection of 2′-deoxy-2′-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity

Nucleic Acids Research

Volumn 43, Issue 20, 2015, Pages 9587-9599

  Ferreira Bravo, Irani Alves ^a,b   Cozens, Christopher ^c   Holliger, Philipp ^c   DeStefano, Jeffrey J ^a,b  

^a University of Maryland   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXY 2' FLUOROARABINONUCLEOTIDE APTAMER; APTAMER; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; DNA; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; AVIAN MYELOBLASTOSIS VIRUS; BASE PAIRING; BINDING AFFINITY; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DNA SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; IONIC STRENGTH; MOLONEY MURINE SARCOMA VIRUS; NONHUMAN; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; METABOLISM; NUCLEOTIDE SEQUENCE; PROCEDURES; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; DNA; HIV REVERSE TRANSCRIPTASE; REVERSE TRANSCRIPTASE INHIBITORS; SELEX APTAMER TECHNIQUE;

EID: 84949959608     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv1057     Document Type: Article

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