The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif

Cell Reports

Volumn 13, Issue 10, 2015, Pages 2219-2231

  Liu, Xingyin ^a   Secombe, Julie ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

H3K4me3; histone; KDM5; Lid; mitochondria; PHD motif; transcription

Indexed keywords

HISTONE DEMETHYLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR KDM5; UNCLASSIFIED DRUG; CHROMATIN; DROSOPHILA PROTEIN; HISTONE; LID PROTEIN, DROSOPHILA;

ADULT; AMINO ACID SEQUENCE; ANAEROBIC GLYCOLYSIS; ARTICLE; BINDING AFFINITY; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; FEMALE; GENE EXPRESSION REGULATION; MICROARRAY ANALYSIS; MITOCHONDRION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; DROSOPHILA MELANOGASTER; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC ANIMAL; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HISTONE DEMETHYLASES; HISTONES; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84949679994     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.11.007     Document Type: Article

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