메뉴 건너뛰기




Volumn 724, Issue , 2012, Pages 291-299

Oxidative stress and mitochondrial dysfunction in down syndrome

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMYLOID PRECURSOR PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; ISOCITRATE DEHYDROGENASE; LEVACECARNINE; MENADIONE; PYRUVATE DEHYDROGENASE; RESVERATROL; ROTENONE; SIRTUIN; THIOCTIC ACID; UBIDECARENONE; SUPEROXIDE DISMUTASE;

EID: 84859508314     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-0653-2_22     Document Type: Article
Times cited : (95)

References (75)
  • 2
    • 0025601495 scopus 로고
    • Intrathymic deficient expansion of T-cell precursors in Down syndrome
    • Musiani P, Valitutti S, Castellino F et al. Intrathymic deficient expansion of T-cell precursors in Down syndrome. Am J Med Genet Suppl 1990; 7:219-224.
    • (1990) Am J Med Genet Suppl , vol.7 , pp. 219-224
    • Musiani, P.1    Valitutti, S.2    Castellino, F.3
  • 3
    • 0035412104 scopus 로고    scopus 로고
    • Pattern of malignant disorders in individuals with Down's syndrome
    • Hasle H. Pattern of malignant disorders in individuals with Down's syndrome. Lancet Oncol 2001;2:429-436.
    • (2001) Lancet Oncol , vol.2 , pp. 429-436
    • Hasle, H.1
  • 4
    • 0034854122 scopus 로고    scopus 로고
    • Down syndrome and Alzheimer's disease: A link between development and aging
    • Lott IT, Head E. Down syndrome and Alzheimer's disease: a link between development and aging. Ment Retard Dev Disabil Res Rev 2001; 7:172-178.
    • (2001) Ment Retard Dev Disabil Res Rev , vol.7 , pp. 172-178
    • Lott, I.T.1    Head, E.2
  • 5
    • 0021485455 scopus 로고
    • Superoxide dismutase, glutathione peroxidase and lipoperoxidation in Down's syndrome fetal brain
    • Brooksbank BW, Balasz R. Superoxide dismutase, glutathione peroxidase and lipoperoxidation in Down's syndrome fetal brain. Exp Brain Res 1984; 16:37-44.
    • (1984) Exp Brain Res , vol.16 , pp. 37-44
    • Brooksbank, B.W.1    Balasz, R.2
  • 6
    • 0023880939 scopus 로고
    • Down's syndrome: A pathology involving the lack of balance of reactive oxygen species
    • Kedziora J, Bartosz G. Down's syndrome: A pathology involving the lack of balance of reactive oxygen species. Free Rad Biol Med 1988; 4:317-330.
    • (1988) Free Rad Biol Med , vol.4 , pp. 317-330
    • Kedziora, J.1    Bartosz, G.2
  • 8
    • 0029417023 scopus 로고
    • Apoptosis and increased generation ofreactive oxygen species in Down's syndrome neurons in vitro
    • Busciglio J, Yankner BA. Apoptosis and increased generation ofreactive oxygen species in Down's syndrome neurons in vitro. Nature 1995; 378:776-779.
    • (1995) Nature , vol.378 , pp. 776-779
    • Busciglio, J.1    Yankner, B.A.2
  • 9
    • 0035226664 scopus 로고    scopus 로고
    • Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease
    • Balcz B, Kirchner L, Cairns N et al. Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease. J Neural Transm Suppl 2001; 61:193-201.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 193-201
    • Balcz, B.1    Kirchner, L.2    Cairns, N.3
  • 10
    • 0023444192 scopus 로고
    • Transgenic mice with increased Cu/Zn-superoxide dismutase activity: Animal model of dosage effects in Down syndrome
    • Epstein CJ, Avraham KB, Lovett M et al. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: Animal model of dosage effects in Down syndrome. Proc Natl Acad Sci USA 1987; 84:8044-8048.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8044-8048
    • Epstein, C.J.1    Avraham, K.B.2    Lovett, M.3
  • 11
    • 0035882353 scopus 로고    scopus 로고
    • Influence of age on activities of antioxidant enzymes and lipid peroxidation products in erythrocytes and neutrophils of Down syndrome patients
    • Muchova J, Sustrova M, Garaiova I et al. Influence of age on activities of antioxidant enzymes and lipid peroxidation products in erythrocytes and neutrophils of Down syndrome patients. Free Radic Biol Med 2001; 31:499-508.
    • (2001) Free Radic Biol Med , vol.31 , pp. 499-508
    • Muchova, J.1    Sustrova, M.2    Garaiova, I.3
  • 12
    • 84859757770 scopus 로고    scopus 로고
    • The relationship between antioxidant systems and some markers of oxidative stress in persons with Down syndrome
    • Garaiova I, Muchova J, Sustrova M et al. The relationship between antioxidant systems and some markers of oxidative stress in persons with Down syndrome. Biologia (Bratislava) 2004; 59:781-788.
    • (2004) Biologia (Bratislava) , vol.59 , pp. 781-788
    • Garaiova, I.1    Muchova, J.2    Sustrova, M.3
  • 13
    • 67249088582 scopus 로고    scopus 로고
    • Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses
    • Slonim DK, Koide K, Johnson KL et al. Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses. Proc Natl Acad Sci USA 2009; 106:9425-9429.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9425-9429
    • Slonim, D.K.1    Koide, K.2    Johnson, K.L.3
  • 14
    • 34548496286 scopus 로고    scopus 로고
    • Altered expression of mitochondrial and extracellular matrix genes in the heart ofhuman fetuses with chromosome 21 trisomy
    • Conti A, Fabbrini F, D'Agostino P et al. Altered expression of mitochondrial and extracellular matrix genes in the heart ofhuman fetuses with chromosome 21 trisomy. BMC Genomics 2007; 8:268.
    • (2007) BMC Genomics , vol.8 , pp. 268
    • Conti, A.1    Fabbrini, F.2    D'Agostino, P.3
  • 15
    • 0031896581 scopus 로고    scopus 로고
    • Antioxidant enzymes and fatty acid status in erythrocytes of Down's syndrome patients
    • Pastor MC, Sierra C, Dolade M et al. Antioxidant enzymes and fatty acid status in erythrocytes of Down's syndrome patients. Clin Chem 1998; 44:924-929.
    • (1998) Clin Chem , vol.44 , pp. 924-929
    • Pastor, M.C.1    Sierra, C.2    Dolade, M.3
  • 16
    • 28544452525 scopus 로고    scopus 로고
    • Oxidative stress and hematologic and biochemical parameters in individuals with Down syndrome
    • Garcez ME, Peres W, Salvador M. Oxidative stress and hematologic and biochemical parameters in individuals with Down syndrome. Mayo Clin Proc 2005; 80:1607-1611.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1607-1611
    • Garcez, M.E.1    Peres, W.2    Salvador, M.3
  • 17
    • 33846522388 scopus 로고    scopus 로고
    • Lipid peroxidation in Down syndrome caused by regular trisomy 21,trisomy21 byRobertsoniantranslocationandmosaictrisomy21
    • Casado A, Lopez-Fernandez ME, RuizR. Lipid peroxidation in Down syndrome caused by regular trisomy 21,trisomy21 byRobertsoniantranslocationandmosaictrisomy21. ClinChemLabMed2007;45:59-62.
    • (2007) ClinChemLabMed , vol.45 , pp. 59-62
    • Casado, A.1    Lopez-Fernandez, M.E.2    Ruiz, R.3
  • 18
    • 33747256270 scopus 로고    scopus 로고
    • Higher age-related prooxidant state in young Down syndrome patients indicates accelerated aging
    • Pallardo FV, Degan P, d'Ischia M et al. Higher age-related prooxidant state in young Down syndrome patients indicates accelerated aging. Biogerontology 2006; 7:211-220.
    • (2006) Biogerontology , vol.7 , pp. 211-220
    • Pallardo, F.V.1    Degan, P.2    D'Ischia, M.3
  • 19
    • 33646905061 scopus 로고    scopus 로고
    • Age-dependent oxidative stress-induced DNA damage in Down's lymphocytes
    • Zana M, Szecsenyi A, Czibula A et al. Age-dependent oxidative stress-induced DNA damage in Down's lymphocytes. Biochem Biophys Res Commun. 2006; 345:726-733.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 726-733
    • Zana, M.1    Szecsenyi, A.2    Czibula, A.3
  • 20
    • 1142273252 scopus 로고    scopus 로고
    • Uric acid and allantoin levels in Down syndrome: Antioxidant and oxidative stress mechanisms?
    • Zitnanova I, Korytar P, Aruoma OI et al. Uric acid and allantoin levels in Down syndrome: antioxidant and oxidative stress mechanisms? Clin Chim Acta 2004; 341:139-146.
    • (2004) Clin Chim Acta , vol.341 , pp. 139-146
    • Zitnanova, I.1    Korytar, P.2    Aruoma, O.I.3
  • 21
    • 77952124987 scopus 로고    scopus 로고
    • Melatonin and elimination of kynurenines in children with Down's syndrome
    • Uberos J, Romero J, Molina-Carballo A et al. Melatonin and elimination of kynurenines in children with Down's syndrome. J Pediatr Endocrinol Metab 2010; 23:277-282.
    • (2010) J Pediatr Endocrinol Metab , vol.23 , pp. 277-282
    • Uberos, J.1    Romero, J.2    Molina-Carballo, A.3
  • 22
    • 77951666984 scopus 로고    scopus 로고
    • Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations
    • Coppus AM, Fekkes D, Verhoeven WM et al. Plasma levels of nitric oxide related amino acids in demented subjects with Down syndrome are related to neopterin concentrations. Amino Acids 2010; 38:923-928.
    • (2010) Amino Acids , vol.38 , pp. 923-928
    • Coppus, A.M.1    Fekkes, D.2    Verhoeven, W.M.3
  • 23
    • 0034084240 scopus 로고    scopus 로고
    • Serum lipid resistance to oxidation and uric acid levels in subjects with Down's syndrome
    • Nagyova A, Sustrova M, Raslova K. Serum lipid resistance to oxidation and uric acid levels in subjects with Down's syndrome. Physiol Res 2000; 49:227-231.
    • (2000) Physiol Res , vol.49 , pp. 227-231
    • Nagyova, A.1    Sustrova, M.2    Raslova, K.3
  • 24
    • 0032401643 scopus 로고    scopus 로고
    • Biomarkers of oxidative stress are significantly elevated in Down syndrome
    • Jovanovic SV, Clements D, MacLeod K. Biomarkers of oxidative stress are significantly elevated in Down syndrome. Free Radic Biol Med 1998; 25:1044-1048.
    • (1998) Free Radic Biol Med , vol.25 , pp. 1044-1048
    • Jovanovic, S.V.1    Clements, D.2    MacLeod, K.3
  • 25
    • 0033761958 scopus 로고    scopus 로고
    • Down's syndrome is associated with increased 8,12-iso-iPF2alpha-VI levels: Evidence for enhanced lipid peroxidation in vivo
    • Pratico D, Iuliano L, Amerio G et al. Down's syndrome is associated with increased 8,12-iso-iPF2alpha-VI levels: evidence for enhanced lipid peroxidation in vivo. Ann Neurol 2000; 48:795-798.
    • (2000) Ann Neurol , vol.48 , pp. 795-798
    • Pratico, D.1    Iuliano, L.2    Amerio, G.3
  • 26
    • 33846237755 scopus 로고    scopus 로고
    • Early oxidative stress in amniotic fluid of pregnancies with Down syndrome
    • Perrone S, Longini M, Bellieni CV et al. Early oxidative stress in amniotic fluid of pregnancies with Down syndrome. Clin Biochem 2007; 40:177-180.
    • (2007) Clin Biochem , vol.40 , pp. 177-180
    • Perrone, S.1    Longini, M.2    Bellieni, C.V.3
  • 27
    • 0014627389 scopus 로고
    • Depressed immunoglobulin G in newborn infants with Down's syndrome
    • Miller ME, Mellman Cohen MM, Kohn G et al. Depressed immunoglobulin G in newborn infants with Down's syndrome. J Pediatr 1969; 75:996-1000.
    • (1969) J Pediatr , vol.75 , pp. 996-1000
    • Miller, M.E.1    Mellman Cohen, M.M.2    Kohn, G.3
  • 28
    • 0016216130 scopus 로고
    • Serum IgE concentration in trisomy 21
    • Lopez V. Serum IgE concentration in trisomy 21. J Ment Defic Res 1974; 18:111-114.
    • (1974) J Ment Defic Res , vol.18 , pp. 111-114
    • Lopez, V.1
  • 29
    • 0018078527 scopus 로고
    • Immunodeficiency in Down's syndrome: T-lymphocyte subset imbalance in trisomic children
    • Burgio GR, Lanzavecchia A, Maccario R et al. Immunodeficiency in Down's syndrome: T-lymphocyte subset imbalance in trisomic children. Clin Exp Immunol 1978; 33:298-301.
    • (1978) Clin Exp Immunol , vol.33 , pp. 298-301
    • Burgio, G.R.1    Lanzavecchia, A.2    MacCario, R.3
  • 31
    • 33644869901 scopus 로고    scopus 로고
    • Inflammation and neurodegenerative diseases
    • Griffin WS. Inflammation and neurodegenerative diseases. Am J Clin Nutr 2006; 83:470S-474S.
    • (2006) Am J Clin Nutr , vol.83
    • Griffin, W.S.1
  • 32
    • 34249898927 scopus 로고    scopus 로고
    • Pro-inflammatory cytokinemia is frequently found in Down syndrome patients with hematological disorders
    • Shimada A, Hayashi Y, Ogasawara M et al. Pro-inflammatory cytokinemia is frequently found in Down syndrome patients with hematological disorders. Leuk Res 2007; 31:1199-1203.
    • (2007) Leuk Res , vol.31 , pp. 1199-1203
    • Shimada, A.1    Hayashi, Y.2    Ogasawara, M.3
  • 33
    • 65549115151 scopus 로고    scopus 로고
    • T-lymphocyte maturation is impaired in healthy young individuals carrying trisomy 21 (Down syndrome)
    • Guazzarotti L, Trabattoni D, Castelletti E et al. T-lymphocyte maturation is impaired in healthy young individuals carrying trisomy 21 (Down syndrome). Am J Intellect Dev Disabil 2009; 114:100-109.
    • (2009) Am J Intellect Dev Disabil , vol.114 , pp. 100-109
    • Guazzarotti, L.1    Trabattoni, D.2    Castelletti, E.3
  • 34
    • 78651103619 scopus 로고    scopus 로고
    • Analysis of peripheral blood T-cell subsets, natural killer cells and serum levels of cytokines in children with Down syndrome
    • Cetiner S, Demirhan O, Inal TC et al. Analysis of peripheral blood T-cell subsets, natural killer cells and serum levels of cytokines in children with Down syndrome. Int J Immunogenet 2010; 37:233-237.
    • (2010) Int J Immunogenet , vol.37 , pp. 233-237
    • Cetiner, S.1    Demirhan, O.2    Inal, T.C.3
  • 35
    • 77950519083 scopus 로고    scopus 로고
    • Distinct abnormalities in the innate immune system of children with Down syndrome
    • Bloemers BL, van Bleek GM, Kimpen JL et al. Distinct abnormalities in the innate immune system of children with Down syndrome. J Pediatr 2010; 156:804-809.
    • (2010) J Pediatr , vol.156 , pp. 804-809
    • Bloemers, B.L.1    Van Bleek, G.M.2    Kimpen, J.L.3
  • 36
    • 77956481391 scopus 로고    scopus 로고
    • Impairment of circulating endothelial progenitors in Down syndrome
    • Costa V, Sommese L, Casamassimi A et al. Impairment of circulating endothelial progenitors in Down syndrome. BMC Med Genomics 2010; 3:40.
    • (2010) BMC Med Genomics , vol.3 , pp. 40
    • Costa, V.1    Sommese, L.2    Casamassimi, A.3
  • 37
    • 77956405386 scopus 로고    scopus 로고
    • Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    • Roberts RA, Smith RA, Safe S et al. Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology 2010; 276:85-94.
    • (2010) Toxicology , vol.276 , pp. 85-94
    • Roberts, R.A.1    Smith, R.A.2    Safe, S.3
  • 38
    • 77950212895 scopus 로고    scopus 로고
    • Inflammation, cytokines, immune response, apolipoprotein E, cholesterol and oxidative stress in Alzheimer disease: Therapeutic implications
    • Candore G, Bulati M, Caruso C et al. Inflammation, cytokines, immune response, apolipoprotein E, cholesterol and oxidative stress in Alzheimer disease: therapeutic implications. Rejuvenation Res 2010; 13:301-313.
    • (2010) Rejuvenation Res , vol.13 , pp. 301-313
    • Candore, G.1    Bulati, M.2    Caruso, C.3
  • 39
    • 77951689435 scopus 로고    scopus 로고
    • Biomarkers of oxidative damage and inflammation in Alzheimer's disease
    • Galasko D, Montine TJ. Biomarkers of oxidative damage and inflammation in Alzheimer's disease. Biomark Med 2010; 4:27-36.
    • (2010) Biomark Med , vol.4 , pp. 27-36
    • Galasko, D.1    Montine, T.J.2
  • 41
    • 0032125668 scopus 로고    scopus 로고
    • Cytoplasmic abnormalities in cultured cerebellar neurons from the trisomy 16 mouse
    • Bersu ET, Ahmad FJ, Schwei MJ et al. Cytoplasmic abnormalities in cultured cerebellar neurons from the trisomy 16 mouse. Brain Res Dev Brain Res 1998; 109:115-120.
    • (1998) Brain Res Dev Brain Res , vol.109 , pp. 115-120
    • Bersu, E.T.1    Ahmad, F.J.2    Schwei, M.J.3
  • 42
    • 0033967558 scopus 로고    scopus 로고
    • Increased mitochondrial superoxide generation in neurons from trisomy 16 mice: A model ofDown's syndrome
    • Schuchmann S, HeinemannU. Increased mitochondrial superoxide generation in neurons from trisomy 16 mice: a model ofDown's syndrome. Free Radic Biol Med 2000; 28:235-250.
    • (2000) Free Radic Biol Med , vol.28 , pp. 235-250
    • Schuchmann, S.1    Heinemann, U.2
  • 43
    • 0037012806 scopus 로고    scopus 로고
    • Evidence for increased mitochondrial superoxide production in Down syndrome
    • Capone G, Kim P, Jovanovich S et al. Evidence for increased mitochondrial superoxide production in Down syndrome. Life Sci 2002; 70:2885-2895.
    • (2002) Life Sci , vol.70 , pp. 2885-2895
    • Capone, G.1    Kim, P.2    Jovanovich, S.3
  • 44
    • 37349091097 scopus 로고    scopus 로고
    • Mitochondrialdysfunctioninmouse trisomy 16 brain
    • BambrickLL,FiskumG.Mitochondrialdysfunctioninmouse trisomy 16 brain. Brain Res 2008; 1188:9-16.
    • (2008) Brain Res , vol.1188 , pp. 9-16
    • Bambrick, L.L.1    Fiskum, G.2
  • 45
    • 0037186074 scopus 로고    scopus 로고
    • Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome
    • Busciglio J, Pelsman A, Wong C et al. Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome. Neuron 2002; 33:677-688.
    • (2002) Neuron , vol.33 , pp. 677-688
    • Busciglio, J.1    Pelsman, A.2    Wong, C.3
  • 46
    • 0031753652 scopus 로고    scopus 로고
    • Defective repair of oxidative damage in mitochondrial DNA in Down's syndrome
    • Druzhyna N, Nair RG, LeDoux SP et al. Defective repair of oxidative damage in mitochondrial DNA in Down's syndrome. Mutat Res 1998; 409:81-89.
    • (1998) Mutat Res , vol.409 , pp. 81-89
    • Druzhyna, N.1    Nair, R.G.2    Ledoux, S.P.3
  • 47
    • 34548496286 scopus 로고    scopus 로고
    • Altered expression of mitochondrial and extracellular matrix genes in the heart ofhuman fetuses with chromosome 21 trisomy
    • Conti A, Fabbrini F, D'Agostino P et al. Altered expression of mitochondrial and extracellular matrix genes in the heart ofhuman fetuses with chromosome 21 trisomy. BMC Genomics 2007; 8:268.
    • (2007) BMC Genomics , vol.8 , pp. 268
    • Conti, A.1    Fabbrini, F.2    D'Agostino, P.3
  • 48
    • 33846483260 scopus 로고    scopus 로고
    • Mitochondrial alterations and tendency to apoptosis in peripheral blood cells from childrenwith Down syndrome
    • Roat E, Prada N, Ferraresi R et al. Mitochondrial alterations and tendency to apoptosis in peripheral blood cells from childrenwith Down syndrome. FEBS Lett 2007; 581:521-525.
    • (2007) FEBS Lett , vol.581 , pp. 521-525
    • Roat, E.1    Prada, N.2    Ferraresi, R.3
  • 49
    • 77954938829 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down syndrome, Fanconi Anaemia and Werner syndrome
    • Pallardo FV, Lloret A, Lebel M et al. Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down syndrome, Fanconi Anaemia and Werner syndrome. Biogerontology 2010; 11:401-419.
    • (2010) Biogerontology , vol.11 , pp. 401-419
    • Pallardo, F.V.1    Lloret, A.2    Lebel, M.3
  • 50
    • 33744454404 scopus 로고    scopus 로고
    • Alzheimer's disease pathogenesis: Role of aging
    • Harman D. Alzheimer's disease pathogenesis: role of aging. Ann NY Acad Sci 2006; 1067:454-460.
    • (2006) Ann NY Acad Sci , vol.1067 , pp. 454-460
    • Harman, D.1
  • 51
    • 3543067962 scopus 로고    scopus 로고
    • Neurodegenerative disorders associated with diabetes mellitus
    • Ristow M. Neurodegenerative disorders associated with diabetes mellitus. J Mol Med 2004; 82:510-529.
    • (2004) J Mol Med , vol.82 , pp. 510-529
    • Ristow, M.1
  • 52
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • McCay CM, Crowell MF, Maynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutrition 1935; 10:63-79.
    • (1935) J Nutrition , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 53
    • 49249100288 scopus 로고    scopus 로고
    • Vasoprotective effects of resveratrol and SIRT1: Attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations
    • Csiszar A, Labinskyy N, Podlutsky A et al. Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol 2008; 294:H2721-H2735.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Csiszar, A.1    Labinskyy, N.2    Podlutsky, A.3
  • 54
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur JA, Pearson KJ, Price NL et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006; 444:337-342.
    • (2006) Nature , vol.444 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 55
    • 36949012725 scopus 로고    scopus 로고
    • The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: An overview
    • Liu J. The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview. Neurochem Res 2008; 33:194-203.
    • (2008) Neurochem Res , vol.33 , pp. 194-203
    • Liu, J.1
  • 56
    • 34447625766 scopus 로고    scopus 로고
    • Mitochondrial ageing and the beneficial role of alpha-lipoic acid
    • Palaniappan AR, Dai A. Mitochondrial ageing and the beneficial role of alpha-lipoic acid. Neurochem Res 2007; 32:1552-1558.
    • (2007) Neurochem Res , vol.32 , pp. 1552-1558
    • Palaniappan, A.R.1    Dai, A.2
  • 57
    • 67349139588 scopus 로고    scopus 로고
    • Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex i
    • Plecita-Hlavata L, Jezek J, Jezek P. Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 2009; 41:1697-1707.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1697-1707
    • Plecita-Hlavata, L.1    Jezek, J.2    Jezek, P.3
  • 58
    • 34248159506 scopus 로고    scopus 로고
    • D-galactose toxicity in mice is associated with mitochondrial dysfunction: Protecting effects of mitochondrial nutrient R-alpha-lipoic acid
    • Long J, Wang X, Gao H et al. D-galactose toxicity in mice is associated with mitochondrial dysfunction: protecting effects of mitochondrial nutrient R-alpha-lipoic acid. Biogerontology 2007; 8:373-381.
    • (2007) Biogerontology , vol.8 , pp. 373-381
    • Long, J.1    Wang, X.2    Gao, H.3
  • 59
    • 0025115244 scopus 로고
    • Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine
    • Gadaleta MN, Petruzzella V, Renis M et al. Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of L-carnitine. Eur J Biochem 1990; 187:501-506.
    • (1990) Eur J Biochem , vol.187 , pp. 501-506
    • Gadaleta, M.N.1    Petruzzella, V.2    Renis, M.3
  • 60
    • 66149090372 scopus 로고    scopus 로고
    • Cytoprotective effect of acetyl-L-carnitine evidenced by analysis of gene expression in the rat brain
    • Traina G, Federighi G, Brunelli M et al. Cytoprotective effect of acetyl-L-carnitine evidenced by analysis of gene expression in the rat brain. Mol Neurobiol 2009; 39:101-106.
    • (2009) Mol Neurobiol , vol.39 , pp. 101-106
    • Traina, G.1    Federighi, G.2    Brunelli, M.3
  • 61
    • 73449116731 scopus 로고    scopus 로고
    • Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation
    • Madiraju P, Pande SV, Prentki M et al. Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation. Epigenetics 2009; 4:399-403.
    • (2009) Epigenetics , vol.4 , pp. 399-403
    • Madiraju, P.1    Pande, S.V.2    Prentki, M.3
  • 62
    • 71549116704 scopus 로고    scopus 로고
    • Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?
    • Rosca MG, Lemieux H, Hoppel CL. Mitochondria in the elderly: is acetylcarnitine a rejuvenator? Adv Drug Deliv Rev 2009; 61:1332-1342.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 1332-1342
    • Rosca, M.G.1    Lemieux, H.2    Hoppel, C.L.3
  • 63
    • 33847000236 scopus 로고    scopus 로고
    • Beneficial effects of creatine, CoQ10 and lipoic acid in mitochondrial disorders
    • Rodriguez MC, Macdonald JR, Mahoney DJ et al. Beneficial effects of creatine, CoQ10 and lipoic acid in mitochondrial disorders. Muscle Nerve 2007; 35:235-242.
    • (2007) Muscle Nerve , vol.35 , pp. 235-242
    • Rodriguez, M.C.1    MacDonald, J.R.2    Mahoney, D.J.3
  • 64
    • 33846233856 scopus 로고    scopus 로고
    • Mitigation of age-dependent oxidative damage to DNA in rat heart by carnitine and lipoic acid
    • Savitha S, Panneerselvam C. Mitigation of age-dependent oxidative damage to DNA in rat heart by carnitine and lipoic acid. Mech Ageing Dev 2007; 128:206-212.
    • (2007) Mech Ageing Dev , vol.128 , pp. 206-212
    • Savitha, S.1    Panneerselvam, C.2
  • 65
    • 57449103542 scopus 로고    scopus 로고
    • Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: Implications for in vivo antioxidant activity
    • Maroz A, Anderson RF, Smith RAJ et al. Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity. Free Radic Biol Med 2009;46:105-109.
    • (2009) Free Radic Biol Med , vol.46 , pp. 105-109
    • Maroz, A.1    Anderson, R.F.2    Smith, R.A.J.3
  • 66
    • 36049028290 scopus 로고    scopus 로고
    • Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21
    • Miles MV, Patterson BJ, Chalfonte-Evans ML et al. Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21. Pediatr Neurol 2007; 37:398-403.
    • (2007) Pediatr Neurol , vol.37 , pp. 398-403
    • Miles, M.V.1    Patterson, B.J.2    Chalfonte-Evans, M.L.3
  • 67
    • 80052630069 scopus 로고    scopus 로고
    • Effect of Coenzyme Q(10) in mitigating oxidative DNA damage in Down syndrome patients, a double blindrandomized controlled trial
    • doi:10.1016/j. neurobiolaging.2009.11.016
    • Tiano L, Carnevali P, Padella L et al. Effect of Coenzyme Q(10) in mitigating oxidative DNA damage in Down syndrome patients, a double blindrandomized controlled trial. Neurobiol Aging 2009; doi:10.1016/j. neurobiolaging.2009.11.016.
    • (2009) Neurobiol Aging
    • Tiano, L.1    Carnevali, P.2    Padella, L.3
  • 68
    • 70249116820 scopus 로고    scopus 로고
    • Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
    • Kaufmann P, Thompson JL, Levy G et al. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Ann Neurol 2009; 66:235-244.
    • (2009) Ann Neurol , vol.66 , pp. 235-244
    • Kaufmann, P.1    Thompson, J.L.2    Levy, G.3
  • 69
    • 34447252358 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease
    • Storch A, Jost WH, Vieregge P et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease. Arch Neurol 2007; 64:938-944.
    • (2007) Arch Neurol , vol.64 , pp. 938-944
    • Storch, A.1    Jost, W.H.2    Vieregge, P.3
  • 70
    • 34247639532 scopus 로고    scopus 로고
    • Effect of coenzyme Q10 on myopathic symptoms in patients treated with statins
    • Caso G, Kelly P, McNurlan MA et al. Effect of coenzyme Q10 on myopathic symptoms in patients treated with statins. Am J Cardiol 2007; 99:1409-1412.
    • (2007) Am J Cardiol , vol.99 , pp. 1409-1412
    • Caso, G.1    Kelly, P.2    McNurlan, M.A.3
  • 71
    • 77954560215 scopus 로고    scopus 로고
    • Complementary therapy in diabetic patients with chronic complications: A pilot study
    • Palacka P, Kucharska J, Murin J et al. Complementary therapy in diabetic patients with chronic complications: a pilot study. Bratisl Lek Listy 2010; 111:205-211.
    • (2010) Bratisl Lek Listy , vol.111 , pp. 205-211
    • Palacka, P.1    Kucharska, J.2    Murin, J.3
  • 72
    • 74949125991 scopus 로고    scopus 로고
    • Improved survival in patients with end-stage cancer treated with coenzyme Q(10) and other antioxidants: A pilot study
    • Hertz N, Lister RE. Improved survival in patients with end-stage cancer treated with coenzyme Q(10) and other antioxidants: a pilot study. J Int Med Res 2009; 37:1961-1971.
    • (2009) J Int Med Res , vol.37 , pp. 1961-1971
    • Hertz, N.1    Lister, R.E.2
  • 73
    • 51249120293 scopus 로고    scopus 로고
    • The mitochondrial cocktail: Rationale for combinednutraceutical therapy inmitochondrial cytopathies
    • Tarnopolsky MA. The mitochondrial cocktail: rationale for combinednutraceutical therapy inmitochondrial cytopathies. Adv Drug Deliv Rev 2008; 60:1561-1567.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1561-1567
    • Ma, T.1
  • 74
    • 53149087460 scopus 로고    scopus 로고
    • Mitochondrial alterations in Parkinson's disease: New clues
    • Vila M, Ramonet D, Perier C. Mitochondrial alterations in Parkinson's disease: new clues. J Neurochem 2008; 107:317-328.
    • (2008) J Neurochem , vol.107 , pp. 317-328
    • Vila, M.1    Ramonet, D.2    Perier, C.3
  • 75
    • 67650732998 scopus 로고    scopus 로고
    • Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
    • Wang X, Su B, Lee HG et al. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci 2009; 28:9090-9103.
    • (2009) J Neurosci , vol.28 , pp. 9090-9103
    • Wang, X.1    Su, B.2    Lee, H.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.