Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism

Nature Communications

Volumn 6, Issue , 2015, Pages

  Torres, Idelisse Ortiz ^a,b   Kuchenbecker, Kristopher M ^a,b   Nnadi, Chimno I ^a,b   Fletterick, Robert J ^a   Kelly, Mark J S ^b   Fujimori, Danica Galonić ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; HISTONE H3; RETINOBLASTOMA BINDING PROTEIN 2; TRYPTOPHAN; CHROMATIN; EGLN2 PROTEIN, HUMAN; GLUTATHIONE TRANSFERASE; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; KDM5A PROTEIN, HUMAN; LYSINE; NUCLEOSOME; PEPTIDE; PROTEIN BINDING; RECOMBINANT PROTEIN;

BIOCHEMICAL COMPOSITION; CHROMOSOME; ENZYME ACTIVITY; PATHOGENICITY; PEPTIDE; PROTEIN;

ARTICLE; BINDING SITE; CATALYSIS; CHROMATIN; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HISTONE DEMETHYLATION; HISTONE METHYLATION; NUCLEAR MAGNETIC RESONANCE; NUCLEOSOME; POSITIVE FEEDBACK; PROTEIN STRUCTURE; ALGORITHM; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; GENE EXPRESSION REGULATION; HUMAN; INSECT; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CELL LINE; CHROMATIN; CIRCULAR DICHROISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE TRANSFERASE; HUMANS; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; INSECTS; KINETICS; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; NUCLEOSOMES; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RETINOBLASTOMA-BINDING PROTEIN 2; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84923380857     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7204     Document Type: Article

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