Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers

Nature Medicine

Volumn 21, Issue 12, 2015, Pages 1514-1520

  McCreery, Melissa Q ^a   Halliwill, Kyle D ^a   Chin, Douglas ^a   Delrosario, Reyno ^a   Hirst, Gillian ^a   Vuong, Peter ^a   Jen, Kuang Yu ^a   Hewinson, James ^b   Adams, David J ^b   Balmain, Allan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BBS9 PROTEIN; CASPASE 8; CELL SURFACE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DCLK1 PROTEIN; DIMETHYLBENZ[A]ANTHRACENE; DNA METHYLTRANSFERASE 1; E1A ASSOCIATED P300 PROTEIN; FLICE INHIBITORY PROTEIN; H RAS PROTEIN; ITPKB PROTEIN; K RAS PROTEIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; KMT2C PROTEIN; NCOR1 PROTEIN; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; NUAK2 PROTEIN; PIK3CA PROTEIN; PROTEIN; ROS1 PROTEIN; SYNE1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 7,12 DIMETHYLBENZ[A]ANTHRACENE; RAS PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER GROWTH; CANCER STAGING; CELL ADHESION; CHEMICALLY INDUCED DISORDER; CHROMOSOME 1; CHROMOSOME 6; CHROMOSOME 7; CLONAL EVOLUTION; COPY NUMBER VARIATION; EXOME; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC HETEROGENEITY; GENOMIC INSTABILITY; HUMAN; IMMUNOSURVEILLANCE; KARYOTYPE; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHYLOGENETIC TREE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CANCER; SQUAMOUS CELL CARCINOMA; ANIMAL; CHEMICALLY INDUCED; CROSS BREEDING; DISEASE COURSE; EPITHELIAL MESENCHYMAL TRANSITION; GENETICS; MUTATION; PATHOLOGY; PHYLOGENY; SECONDARY; SKIN TUMOR;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOMA, SQUAMOUS CELL; CLONAL EVOLUTION; CROSSES, GENETIC; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MALE; MICE; MUTATION; PHYLOGENY; RAS PROTEINS; SKIN NEOPLASMS;

EID: 84949623613     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3979     Document Type: Article

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