-
1
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
J.A. Aguirre-Ghiso Models, mechanisms and clinical evidence for cancer dormancy Nat. Rev. Cancer 7 2007 834 846
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
2
-
-
0035172910
-
Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo
-
J.A. Aguirre-Ghiso, D. Liu, A. Mignatti, K. Kovalski, and L. Ossowski Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo Mol. Biol. Cell 12 2001 863 879
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 863-879
-
-
Aguirre-Ghiso, J.A.1
Liu, D.2
Mignatti, A.3
Kovalski, K.4
Ossowski, L.5
-
3
-
-
0037379794
-
ERK(MAPK) activity as a determinant of tumor growth and dormancy; Regulation by p38(SAPK)
-
J.A. Aguirre-Ghiso, Y. Estrada, D. Liu, and L. Ossowski ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK) Cancer Res. 63 2003 1684 1695
-
(2003)
Cancer Res.
, vol.63
, pp. 1684-1695
-
-
Aguirre-Ghiso, J.A.1
Estrada, Y.2
Liu, D.3
Ossowski, L.4
-
4
-
-
1542268981
-
For the long run: Maintaining germinal niches in the adult brain
-
A. Alvarez-Buylla, and D.A. Lim For the long run: maintaining germinal niches in the adult brain Neuron 41 2004 683 686
-
(2004)
Neuron
, vol.41
, pp. 683-686
-
-
Alvarez-Buylla, A.1
Lim, D.A.2
-
5
-
-
83255186736
-
Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
-
M.L. Asselin-Labat, K.D. Sutherland, F. Vaillant, D.E. Gyorki, D. Wu, S. Holroyd, K. Breslin, T. Ward, W. Shi, and M.L. Bath Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14 Mol. Cell. Biol. 31 2011 4609 4622
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 4609-4622
-
-
Asselin-Labat, M.L.1
Sutherland, K.D.2
Vaillant, F.3
Gyorki, D.E.4
Wu, D.5
Holroyd, S.6
Breslin, K.7
Ward, T.8
Shi, W.9
Bath, M.L.10
-
6
-
-
77955021301
-
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment
-
D. Barkan, L.H. El Touny, A.M. Michalowski, J.A. Smith, I. Chu, A.S. Davis, J.D. Webster, S. Hoover, R.M. Simpson, J. Gauldie, and J.E. Green Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment Cancer Res. 70 2010 5706 5716
-
(2010)
Cancer Res.
, vol.70
, pp. 5706-5716
-
-
Barkan, D.1
El Touny, L.H.2
Michalowski, A.M.3
Smith, J.A.4
Chu, I.5
Davis, A.S.6
Webster, J.D.7
Hoover, S.8
Simpson, R.M.9
Gauldie, J.10
Green, J.E.11
-
7
-
-
80053144962
-
A decade of exploring the cancer epigenome - Biological and translational implications
-
S.B. Baylin, and P.A. Jones A decade of exploring the cancer epigenome - biological and translational implications Nat. Rev. Cancer 11 2011 726 734
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
8
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
I. Ben-Porath, M.W. Thomson, V.J. Carey, R. Ge, G.W. Bell, A. Regev, and R.A. Weinberg An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors Nat. Genet. 40 2008 499 507
-
(2008)
Nat. Genet.
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
9
-
-
84872009392
-
Fibronectin regulates Wnt7a signaling and satellite cell expansion
-
C.F. Bentzinger, Y.X. Wang, J. von Maltzahn, V.D. Soleimani, H. Yin, and M.A. Rudnicki Fibronectin regulates Wnt7a signaling and satellite cell expansion Cell Stem Cell 12 2013 75 87
-
(2013)
Cell Stem Cell
, vol.12
, pp. 75-87
-
-
Bentzinger, C.F.1
Wang, Y.X.2
Von Maltzahn, J.3
Soleimani, V.D.4
Yin, H.5
Rudnicki, M.A.6
-
10
-
-
7444266695
-
Donor transmitted malignancies
-
J.F. Buell, T.M. Beebe, J. Trofe, T.G. Gross, R.R. Alloway, M.J. Hanaway, and E.S. Woodle Donor transmitted malignancies Ann. Transplant. 9 2004 53 56
-
(2004)
Ann. Transplant.
, vol.9
, pp. 53-56
-
-
Buell, J.F.1
Beebe, T.M.2
Trofe, J.3
Gross, T.G.4
Alloway, R.R.5
Hanaway, M.J.6
Woodle, E.S.7
-
11
-
-
0034193321
-
Temporal progression of metastasis in lung: Cell survival, dormancy, and location dependence of metastatic inefficiency
-
M.D. Cameron, E.E. Schmidt, N. Kerkvliet, K.V. Nadkarni, V.L. Morris, A.C. Groom, A.F. Chambers, and I.C. MacDonald Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency Cancer Res. 60 2000 2541 2546
-
(2000)
Cancer Res.
, vol.60
, pp. 2541-2546
-
-
Cameron, M.D.1
Schmidt, E.E.2
Kerkvliet, N.3
Nadkarni, K.V.4
Morris, V.L.5
Groom, A.C.6
Chambers, A.F.7
Macdonald, I.C.8
-
12
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
P.J. Campbell, S. Yachida, L.J. Mudie, P.J. Stephens, E.D. Pleasance, L.A. Stebbings, L.A. Morsberger, C. Latimer, S. McLaren, and M.L. Lin The patterns and dynamics of genomic instability in metastatic pancreatic cancer Nature 467 2010 1109 1113
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
Yachida, S.2
Mudie, L.J.3
Stephens, P.J.4
Pleasance, E.D.5
Stebbings, L.A.6
Morsberger, L.A.7
Latimer, C.8
McLaren, S.9
Lin, M.L.10
-
13
-
-
79953147370
-
A perspective on cancer cell metastasis
-
C.L. Chaffer, and R.A. Weinberg A perspective on cancer cell metastasis Science 331 2011 1559 1564
-
(2011)
Science
, vol.331
, pp. 1559-1564
-
-
Chaffer, C.L.1
Weinberg, R.A.2
-
14
-
-
33845809125
-
Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
-
C.L. Chaffer, J.P. Brennan, J.L. Slavin, T. Blick, E.W. Thompson, and E.D. Williams Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2 Cancer Res. 66 2006 11271 11278
-
(2006)
Cancer Res.
, vol.66
, pp. 11271-11278
-
-
Chaffer, C.L.1
Brennan, J.P.2
Slavin, J.L.3
Blick, T.4
Thompson, E.W.5
Williams, E.D.6
-
15
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
C.L. Chaffer, N.D. Marjanovic, T. Lee, G. Bell, C.G. Kleer, F. Reinhardt, A.C. D'Alessio, R.A. Young, and R.A. Weinberg Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity Cell 154 2013 61 74
-
(2013)
Cell
, vol.154
, pp. 61-74
-
-
Chaffer, C.L.1
Marjanovic, N.D.2
Lee, T.3
Bell, G.4
Kleer, C.G.5
Reinhardt, F.6
D'Alessio, A.C.7
Young, R.A.8
Weinberg, R.A.9
-
16
-
-
80054725681
-
Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs
-
Q. Chen, X.H. Zhang, and J. Massagué Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs Cancer Cell 20 2011 538 549
-
(2011)
Cancer Cell
, vol.20
, pp. 538-549
-
-
Chen, Q.1
Zhang, X.H.2
Massagué, J.3
-
17
-
-
84873364088
-
GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression
-
J. Chou, J.H. Lin, A. Brenot, J.W. Kim, S. Provot, and Z. Werb GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression Nat. Cell Biol. 15 2013 201 213
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 201-213
-
-
Chou, J.1
Lin, J.H.2
Brenot, A.3
Kim, J.W.4
Provot, S.5
Werb, Z.6
-
18
-
-
80054012347
-
Developmental and pathological angiogenesis
-
A.S. Chung, and N. Ferrara Developmental and pathological angiogenesis Annu. Rev. Cell Dev. Biol. 27 2011 563 584
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 563-584
-
-
Chung, A.S.1
Ferrara, N.2
-
19
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
H. Clevers The cancer stem cell: premises, promises and challenges Nat. Med. 17 2011 313 319
-
(2011)
Nat. Med.
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
20
-
-
84861986053
-
Wnt/β-catenin signaling and disease
-
H. Clevers, and R. Nusse Wnt/β-catenin signaling and disease Cell 149 2012 1192 1205
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
21
-
-
84875445066
-
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis
-
T.R. Cox, D. Bird, A.M. Baker, H.E. Barker, M.W. Ho, G. Lang, and J.T. Erler LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis Cancer Res. 73 2013 1721 1732
-
(2013)
Cancer Res.
, vol.73
, pp. 1721-1732
-
-
Cox, T.R.1
Bird, D.2
Baker, A.M.3
Barker, H.E.4
Ho, M.W.5
Lang, G.6
Erler, J.T.7
-
22
-
-
36549069842
-
Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: Learning from failures
-
R. Demicheli, M.W. Retsky, W.J. Hrushesky, and M. Baum Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures Nat. Clin. Pract. Oncol. 4 2007 699 710
-
(2007)
Nat. Clin. Pract. Oncol.
, vol.4
, pp. 699-710
-
-
Demicheli, R.1
Retsky, M.W.2
Hrushesky, W.J.3
Baum, M.4
-
23
-
-
80053904142
-
Distinct types of tumor-initiating cells form human colon cancer tumors and metastases
-
S.M. Dieter, C.R. Ball, C.M. Hoffmann, A. Nowrouzi, F. Herbst, O. Zavidij, U. Abel, A. Arens, W. Weichert, and K. Brand Distinct types of tumor-initiating cells form human colon cancer tumors and metastases Cell Stem Cell 9 2011 357 365
-
(2011)
Cell Stem Cell
, vol.9
, pp. 357-365
-
-
Dieter, S.M.1
Ball, C.R.2
Hoffmann, C.M.3
Nowrouzi, A.4
Herbst, F.5
Zavidij, O.6
Abel, U.7
Arens, A.8
Weichert, W.9
Brand, K.10
-
24
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
L. Ding, M.J. Ellis, S. Li, D.E. Larson, K. Chen, J.W. Wallis, C.C. Harris, M.D. McLellan, R.S. Fulton, and L.L. Fulton Genome remodelling in a basal-like breast cancer metastasis and xenograft Nature 464 2010 999 1005
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
Larson, D.E.4
Chen, K.5
Wallis, J.W.6
Harris, C.C.7
McLellan, M.D.8
Fulton, R.S.9
Fulton, L.L.10
-
25
-
-
79551519982
-
Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice
-
M. Elkabets, A.M. Gifford, C. Scheel, B. Nilsson, F. Reinhardt, M.A. Bray, A.E. Carpenter, K. Jirström, K. Magnusson, and B.L. Ebert Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice J. Clin. Invest. 121 2011 784 799
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 784-799
-
-
Elkabets, M.1
Gifford, A.M.2
Scheel, C.3
Nilsson, B.4
Reinhardt, F.5
Bray, M.A.6
Carpenter, A.E.7
Jirström, K.8
Magnusson, K.9
Ebert, B.L.10
-
26
-
-
77953225810
-
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
-
J. Eyles, A.L. Puaux, X. Wang, B. Toh, C. Prakash, M. Hong, T.G. Tan, L. Zheng, L.C. Ong, and Y. Jin Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma J. Clin. Invest. 120 2010 2030 2039
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2030-2039
-
-
Eyles, J.1
Puaux, A.L.2
Wang, X.3
Toh, B.4
Prakash, C.5
Hong, M.6
Tan, T.G.7
Zheng, L.8
Ong, L.C.9
Jin, Y.10
-
27
-
-
0038481970
-
The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
-
I.J. Fidler The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited Nat. Rev. Cancer 3 2003 453 458
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 453-458
-
-
Fidler, I.J.1
-
28
-
-
0019941487
-
Biological diversity in metastatic neoplasms: Origins and implications
-
I.J. Fidler, and I.R. Hart Biological diversity in metastatic neoplasms: origins and implications Science 217 1982 998 1003
-
(1982)
Science
, vol.217
, pp. 998-1003
-
-
Fidler, I.J.1
Hart, I.R.2
-
29
-
-
34248222598
-
Prostate specific antigen recurrence after definitive therapy
-
S.J. Freedland, and J.W. Moul Prostate specific antigen recurrence after definitive therapy J. Urol. 177 2007 1985 1991
-
(2007)
J. Urol.
, vol.177
, pp. 1985-1991
-
-
Freedland, S.J.1
Moul, J.W.2
-
30
-
-
38149006909
-
Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
-
D. Gao, D.J. Nolan, A.S. Mellick, K. Bambino, K. McDonnell, and V. Mittal Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis Science 319 2008 195 198
-
(2008)
Science
, vol.319
, pp. 195-198
-
-
Gao, D.1
Nolan, D.J.2
Mellick, A.S.3
Bambino, K.4
McDonnell, K.5
Mittal, V.6
-
31
-
-
84858199187
-
Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition
-
D. Gao, N. Joshi, H. Choi, S. Ryu, M. Hahn, R. Catena, H. Sadik, P. Argani, P. Wagner, and L.T. Vahdat Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition Cancer Res. 72 2012 1384 1394
-
(2012)
Cancer Res.
, vol.72
, pp. 1384-1394
-
-
Gao, D.1
Joshi, N.2
Choi, H.3
Ryu, S.4
Hahn, M.5
Catena, R.6
Sadik, H.7
Argani, P.8
Wagner, P.9
Vahdat, L.T.10
-
32
-
-
84865218588
-
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites
-
H. Gao, G. Chakraborty, A.P. Lee-Lim, Q. Mo, M. Decker, A. Vonica, R. Shen, E. Brogi, A.H. Brivanlou, and F.G. Giancotti The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites Cell 150 2012 764 779
-
(2012)
Cell
, vol.150
, pp. 764-779
-
-
Gao, H.1
Chakraborty, G.2
Lee-Lim, A.P.3
Mo, Q.4
Decker, M.5
Vonica, A.6
Shen, R.7
Brogi, E.8
Brivanlou, A.H.9
Giancotti, F.G.10
-
33
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
M. Gerlinger, A.J. Rowan, S. Horswell, J. Larkin, D. Endesfelder, E. Gronroos, P. Martinez, N. Matthews, A. Stewart, and P. Tarpey Intratumor heterogeneity and branched evolution revealed by multiregion sequencing N. Engl. J. Med. 366 2012 883 892
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
-
34
-
-
84880332704
-
The perivascular niche regulates breast tumour dormancy
-
C.M. Ghajar, H. Peinado, H. Mori, I.R. Matei, K.J. Evason, H. Brazier, D. Almeida, A. Koller, K.A. Hajjar, and D.Y. Stainier The perivascular niche regulates breast tumour dormancy Nat. Cell Biol. 15 2013 807 817
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 807-817
-
-
Ghajar, C.M.1
Peinado, H.2
Mori, H.3
Matei, I.R.4
Evason, K.J.5
Brazier, H.6
Almeida, D.7
Koller, A.8
Hajjar, K.A.9
Stainier, D.Y.10
-
36
-
-
58549119806
-
Introduction: Unknown primary cancer
-
F.A. Greco, and J.D. Hainsworth Introduction: unknown primary cancer Semin. Oncol. 36 2009 6 7
-
(2009)
Semin. Oncol.
, vol.36
, pp. 6-7
-
-
Greco, F.A.1
Hainsworth, J.D.2
-
37
-
-
84857817163
-
Slug and Sox9 cooperatively determine the mammary stem cell state
-
W. Guo, Z. Keckesova, J.L. Donaher, T. Shibue, V. Tischler, F. Reinhardt, S. Itzkovitz, A. Noske, U. Zürrer-Härdi, and G. Bell Slug and Sox9 cooperatively determine the mammary stem cell state Cell 148 2012 1015 1028
-
(2012)
Cell
, vol.148
, pp. 1015-1028
-
-
Guo, W.1
Keckesova, Z.2
Donaher, J.L.3
Shibue, T.4
Tischler, V.5
Reinhardt, F.6
Itzkovitz, S.7
Noske, A.8
Zürrer-Härdi, U.9
Bell, G.10
-
38
-
-
37649001973
-
ID genes mediate tumor reinitiation during breast cancer lung metastasis
-
G.P. Gupta, J. Perk, S. Acharyya, P. de Candia, V. Mittal, K. Todorova-Manova, W.L. Gerald, E. Brogi, R. Benezra, and J. Massagué ID genes mediate tumor reinitiation during breast cancer lung metastasis Proc. Natl. Acad. Sci. USA 104 2007 19506 19511
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 19506-19511
-
-
Gupta, G.P.1
Perk, J.2
Acharyya, S.3
De Candia, P.4
Mittal, V.5
Todorova-Manova, K.6
Gerald, W.L.7
Brogi, E.8
Benezra, R.9
Massagué, J.10
-
40
-
-
84865241459
-
The Notch signalling system: Recent insights into the complexity of a conserved pathway
-
K.G. Guruharsha, M.W. Kankel, and S. Artavanis-Tsakonas The Notch signalling system: recent insights into the complexity of a conserved pathway Nat. Rev. Genet. 13 2012 654 666
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 654-666
-
-
Guruharsha, K.G.1
Kankel, M.W.2
Artavanis-Tsakonas, S.3
-
41
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
D. Hanahan, and J. Folkman Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 1996 353 364
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
42
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
P.C. Hermann, S.L. Huber, T. Herrler, A. Aicher, J.W. Ellwart, M. Guba, C.J. Bruns, and C. Heeschen Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 2007 313 323
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
Bruns, C.J.7
Heeschen, C.8
-
43
-
-
0028951043
-
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
-
L. Holmgren, M.S. O'Reilly, and J. Folkman Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression Nat. Med. 1 1995 149 153
-
(1995)
Nat. Med.
, vol.1
, pp. 149-153
-
-
Holmgren, L.1
O'Reilly, M.S.2
Folkman, J.3
-
44
-
-
84856078085
-
A family business: Stem cell progeny join the niche to regulate homeostasis
-
Y.C. Hsu, and E. Fuchs A family business: stem cell progeny join the niche to regulate homeostasis Nat. Rev. Mol. Cell Biol. 13 2012 103 114
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 103-114
-
-
Hsu, Y.C.1
Fuchs, E.2
-
45
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Y. Hüsemann, J.B. Geigl, F. Schubert, P. Musiani, M. Meyer, E. Burghart, G. Forni, R. Eils, T. Fehm, G. Riethmüller, and C.A. Klein Systemic spread is an early step in breast cancer Cancer Cell 13 2008 58 68
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Hüsemann, Y.1
Geigl, J.B.2
Schubert, F.3
Musiani, P.4
Meyer, M.5
Burghart, E.6
Forni, G.7
Eils, R.8
Fehm, T.9
Riethmüller, G.10
Klein, C.A.11
-
46
-
-
63049104211
-
Microenvironmental regulation of metastasis
-
J.A. Joyce, and J.W. Pollard Microenvironmental regulation of metastasis Nat. Rev. Cancer 9 2009 239 252
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 239-252
-
-
Joyce, J.A.1
Pollard, J.W.2
-
47
-
-
84877816994
-
Tumor cell dissemination: Emerging biological insights from animal models and cancer patients
-
Y. Kang, and K. Pantel Tumor cell dissemination: emerging biological insights from animal models and cancer patients Cancer Cell 23 2013 573 581
-
(2013)
Cancer Cell
, vol.23
, pp. 573-581
-
-
Kang, Y.1
Pantel, K.2
-
48
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Y. Kang, P.M. Siegel, W. Shu, M. Drobnjak, S.M. Kakonen, C. Cordón-Cardo, T.A. Guise, and J. Massagué A multigenic program mediating breast cancer metastasis to bone Cancer Cell 3 2003 537 549
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordón-Cardo, C.6
Guise, T.A.7
Massagué, J.8
-
49
-
-
67749118424
-
Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1
-
S.Y. Kang, O.J. Halvorsen, K. Gravdal, N. Bhattacharya, J.M. Lee, N.W. Liu, B.T. Johnston, A.B. Johnston, S.A. Haukaas, and K. Aamodt Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1 Proc. Natl. Acad. Sci. USA 106 2009 12115 12120
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12115-12120
-
-
Kang, S.Y.1
Halvorsen, O.J.2
Gravdal, K.3
Bhattacharya, N.4
Lee, J.M.5
Liu, N.W.6
Johnston, B.T.7
Johnston, A.B.8
Haukaas, S.A.9
Aamodt, K.10
-
51
-
-
77954740501
-
Metastatic behavior of breast cancer subtypes
-
H. Kennecke, R. Yerushalmi, R. Woods, M.C. Cheang, D. Voduc, C.H. Speers, T.O. Nielsen, and K. Gelmon Metastatic behavior of breast cancer subtypes J. Clin. Oncol. 28 2010 3271 3277
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3271-3277
-
-
Kennecke, H.1
Yerushalmi, R.2
Woods, R.3
Cheang, M.C.4
Voduc, D.5
Speers, C.H.6
Nielsen, T.O.7
Gelmon, K.8
-
52
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
S. Kim, H. Takahashi, W.W. Lin, P. Descargues, S. Grivennikov, Y. Kim, J.L. Luo, and M. Karin Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis Nature 457 2009 102 106
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
53
-
-
0034890326
-
Biological behavior of human breast cancer micrometastases
-
N. Klauber-DeMore, K.J. Van Zee, I. Linkov, P.I. Borgen, and W.L. Gerald Biological behavior of human breast cancer micrometastases Clin. Cancer Res. 7 2001 2434 2439
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 2434-2439
-
-
Klauber-Demore, N.1
Van Zee, K.J.2
Linkov, I.3
Borgen, P.I.4
Gerald, W.L.5
-
54
-
-
63049102497
-
Parallel progression of primary tumours and metastases
-
C.A. Klein Parallel progression of primary tumours and metastases Nat. Rev. Cancer 9 2009 302 312
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 302-312
-
-
Klein, C.A.1
-
55
-
-
84862917865
-
Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
-
A. Kobayashi, H. Okuda, F. Xing, P.R. Pandey, M. Watabe, S. Hirota, S.K. Pai, W. Liu, K. Fukuda, and C. Chambers Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone J. Exp. Med. 208 2011 2641 2655
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2641-2655
-
-
Kobayashi, A.1
Okuda, H.2
Xing, F.3
Pandey, P.R.4
Watabe, M.5
Hirota, S.6
Pai, S.K.7
Liu, W.8
Fukuda, K.9
Chambers, C.10
-
56
-
-
80052470207
-
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
-
M. Korpal, B.J. Ell, F.M. Buffa, T. Ibrahim, M.A. Blanco, T. Celià-Terrassa, L. Mercatali, Z. Khan, H. Goodarzi, and Y. Hua Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization Nat. Med. 17 2011 1101 1108
-
(2011)
Nat. Med.
, vol.17
, pp. 1101-1108
-
-
Korpal, M.1
Ell, B.J.2
Buffa, F.M.3
Ibrahim, T.4
Blanco, M.A.5
Celià- Terrassa, T.6
Mercatali, L.7
Khan, Z.8
Goodarzi, H.9
Hua, Y.10
-
57
-
-
38549131901
-
GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
-
H. Kouros-Mehr, S.K. Bechis, E.M. Slorach, L.E. Littlepage, M. Egeblad, A.J. Ewald, S.Y. Pai, I.C. Ho, and Z. Werb GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model Cancer Cell 13 2008 141 152
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
Bechis, S.K.2
Slorach, E.M.3
Littlepage, L.E.4
Egeblad, M.5
Ewald, A.J.6
Pai, S.Y.7
Ho, I.C.8
Werb, Z.9
-
58
-
-
84873084388
-
Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer
-
A. Kreso, C.A. O'Brien, P. van Galen, O.I. Gan, F. Notta, A.M. Brown, K. Ng, J. Ma, E. Wienholds, and C. Dunant Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer Science 339 2013 543 548
-
(2013)
Science
, vol.339
, pp. 543-548
-
-
Kreso, A.1
O'Brien, C.A.2
Van Galen, P.3
Gan, O.I.4
Notta, F.5
Brown, A.M.6
Ng, K.7
Ma, J.8
Wienholds, E.9
Dunant, C.10
-
59
-
-
79960006754
-
CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation
-
T.K. Lee, A. Castilho, V.C. Cheung, K.H. Tang, S. Ma, and I.O. Ng CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation Cell Stem Cell 9 2011 50 63
-
(2011)
Cell Stem Cell
, vol.9
, pp. 50-63
-
-
Lee, T.K.1
Castilho, A.2
Cheung, V.C.3
Tang, K.H.4
Ma, S.5
Ng, I.O.6
-
60
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
K.R. Levental, H. Yu, L. Kass, J.N. Lakins, M. Egeblad, J.T. Erler, S.F. Fong, K. Csiszar, A. Giaccia, and W. Weninger Matrix crosslinking forces tumor progression by enhancing integrin signaling Cell 139 2009 891 906
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
Fong, S.F.7
Csiszar, K.8
Giaccia, A.9
Weninger, W.10
-
61
-
-
0036596352
-
EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma
-
D. Liu, J. Aguirre Ghiso, Y. Estrada, and L. Ossowski EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma Cancer Cell 1 2002 445 457
-
(2002)
Cancer Cell
, vol.1
, pp. 445-457
-
-
Liu, D.1
Aguirre Ghiso, J.2
Estrada, Y.3
Ossowski, L.4
-
62
-
-
9244224723
-
Intrinsic tumour suppression
-
S.W. Lowe, E. Cepero, and G. Evan Intrinsic tumour suppression Nature 432 2004 307 315
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
63
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
Z. Lu, R.Z. Luo, Y. Lu, X. Zhang, Q. Yu, S. Khare, S. Kondo, Y. Kondo, Y. Yu, and G.B. Mills The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells J. Clin. Invest. 118 2008 3917 3929
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3917-3929
-
-
Lu, Z.1
Luo, R.Z.2
Lu, Y.3
Zhang, X.4
Yu, Q.5
Khare, S.6
Kondo, S.7
Kondo, Y.8
Yu, Y.9
Mills, G.B.10
-
64
-
-
83455208311
-
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors
-
X. Lu, E. Mu, Y. Wei, S. Riethdorf, Q. Yang, M. Yuan, J. Yan, Y. Hua, B.J. Tiede, and X. Lu VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors Cancer Cell 20 2011 701 714
-
(2011)
Cancer Cell
, vol.20
, pp. 701-714
-
-
Lu, X.1
Mu, E.2
Wei, Y.3
Riethdorf, S.4
Yang, Q.5
Yuan, M.6
Yan, J.7
Hua, Y.8
Tiede, B.J.9
Lu, X.10
-
65
-
-
0031655802
-
Multistep nature of metastatic inefficiency: Dormancy of solitary cells after successful extravasation and limited survival of early micrometastases
-
K.J. Luzzi, I.C. MacDonald, E.E. Schmidt, N. Kerkvliet, V.L. Morris, A.F. Chambers, and A.C. Groom Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases Am. J. Pathol. 153 1998 865 873
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 865-873
-
-
Luzzi, K.J.1
Macdonald, I.C.2
Schmidt, E.E.3
Kerkvliet, N.4
Morris, V.L.5
Chambers, A.F.6
Groom, A.C.7
-
66
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
I. Malanchi, A. Santamaria-Martínez, E. Susanto, H. Peng, H.A. Lehr, J.F. Delaloye, and J. Huelsken Interactions between cancer stem cells and their niche govern metastatic colonization Nature 481 2012 85 89
-
(2012)
Nature
, vol.481
, pp. 85-89
-
-
Malanchi, I.1
Santamaria-Martínez, A.2
Susanto, E.3
Peng, H.4
Lehr, H.A.5
Delaloye, J.F.6
Huelsken, J.7
-
67
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
S.A. Mani, W. Guo, M.J. Liao, E.N. Eaton, A. Ayyanan, A.Y. Zhou, M. Brooks, F. Reinhard, C.C. Zhang, and M. Shipitsin The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 2008 704 715
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
-
68
-
-
79953750307
-
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
-
R. Mazzieri, F. Pucci, D. Moi, E. Zonari, A. Ranghetti, A. Berti, L.S. Politi, B. Gentner, J.L. Brown, L. Naldini, and M. De Palma Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells Cancer Cell 19 2011 512 526
-
(2011)
Cancer Cell
, vol.19
, pp. 512-526
-
-
Mazzieri, R.1
Pucci, F.2
Moi, D.3
Zonari, E.4
Ranghetti, A.5
Berti, A.6
Politi, L.S.7
Gentner, B.8
Brown, J.L.9
Naldini, L.10
De Palma, M.11
-
69
-
-
44649088833
-
Systemic endocrine instigation of indolent tumor growth requires osteopontin
-
S.S. McAllister, A.M. Gifford, A.L. Greiner, S.P. Kelleher, M.P. Saelzler, T.A. Ince, F. Reinhardt, L.N. Harris, B.L. Hylander, E.A. Repasky, and R.A. Weinberg Systemic endocrine instigation of indolent tumor growth requires osteopontin Cell 133 2008 994 1005
-
(2008)
Cell
, vol.133
, pp. 994-1005
-
-
McAllister, S.S.1
Gifford, A.M.2
Greiner, A.L.3
Kelleher, S.P.4
Saelzler, M.P.5
Ince, T.A.6
Reinhardt, F.7
Harris, L.N.8
Hylander, B.L.9
Repasky, E.A.10
Weinberg, R.A.11
-
70
-
-
0019426991
-
Renal cell carcinoma: Long-term survival and late recurrence
-
D.W. McNichols, J.W. Segura, and J.H. DeWeerd Renal cell carcinoma: long-term survival and late recurrence J. Urol. 126 1981 17 23
-
(1981)
J. Urol.
, vol.126
, pp. 17-23
-
-
McNichols, D.W.1
Segura, J.W.2
Deweerd, J.H.3
-
71
-
-
52049103847
-
The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
-
M.B. Meads, L.A. Hazlehurst, and W.S. Dalton The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance Clin. Cancer Res. 14 2008 2519 2526
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 2519-2526
-
-
Meads, M.B.1
Hazlehurst, L.A.2
Dalton, W.S.3
-
73
-
-
9444297917
-
Coregulation of fibronectin signaling and matrix contraction by tenascin-C and syndecan-4
-
K.S. Midwood, L.V. Valenick, H.C. Hsia, and J.E. Schwarzbauer Coregulation of fibronectin signaling and matrix contraction by tenascin-C and syndecan-4 Mol. Biol. Cell 15 2004 5670 5677
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 5670-5677
-
-
Midwood, K.S.1
Valenick, L.V.2
Hsia, H.C.3
Schwarzbauer, J.E.4
-
74
-
-
24944450362
-
The transcriptional repressor Snail promotes mammary tumor recurrence
-
S.E. Moody, D. Perez, T.C. Pan, C.J. Sarkisian, C.P. Portocarrero, C.J. Sterner, K.L. Notorfrancesco, R.D. Cardiff, and L.A. Chodosh The transcriptional repressor Snail promotes mammary tumor recurrence Cancer Cell 8 2005 197 209
-
(2005)
Cancer Cell
, vol.8
, pp. 197-209
-
-
Moody, S.E.1
Perez, D.2
Pan, T.C.3
Sarkisian, C.J.4
Portocarrero, C.P.5
Sterner, C.J.6
Notorfrancesco, K.L.7
Cardiff, R.D.8
Chodosh, L.A.9
-
75
-
-
39149144034
-
Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life
-
S.J. Morrison, and A.C. Spradling Stem cells and niches: mechanisms that promote stem cell maintenance throughout life Cell 132 2008 598 611
-
(2008)
Cell
, vol.132
, pp. 598-611
-
-
Morrison, S.J.1
Spradling, A.C.2
-
76
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
G.R. Mundy Metastasis to bone: causes, consequences and therapeutic opportunities Nat. Rev. Cancer 2 2002 584 593
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
77
-
-
84870168239
-
Cell polarity as a regulator of cancer cell behavior plasticity
-
S.K. Muthuswamy, and B. Xue Cell polarity as a regulator of cancer cell behavior plasticity Annu. Rev. Cell Dev. Biol. 28 2012 599 625
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 599-625
-
-
Muthuswamy, S.K.1
Xue, B.2
-
78
-
-
0036532065
-
Persistence of solitary mammary carcinoma cells in a secondary site: A possible contributor to dormancy
-
G.N. Naumov, I.C. MacDonald, P.M. Weinmeister, N. Kerkvliet, K.V. Nadkarni, S.M. Wilson, V.L. Morris, A.C. Groom, and A.F. Chambers Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy Cancer Res. 62 2002 2162 2168
-
(2002)
Cancer Res.
, vol.62
, pp. 2162-2168
-
-
Naumov, G.N.1
Macdonald, I.C.2
Weinmeister, P.M.3
Kerkvliet, N.4
Nadkarni, K.V.5
Wilson, S.M.6
Morris, V.L.7
Groom, A.C.8
Chambers, A.F.9
-
79
-
-
0347504928
-
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases
-
G.N. Naumov, J.L. Townson, I.C. MacDonald, S.M. Wilson, V.H. Bramwell, A.C. Groom, and A.F. Chambers Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases Breast Cancer Res. Treat. 82 2003 199 206
-
(2003)
Breast Cancer Res. Treat.
, vol.82
, pp. 199-206
-
-
Naumov, G.N.1
Townson, J.L.2
Macdonald, I.C.3
Wilson, S.M.4
Bramwell, V.H.5
Groom, A.C.6
Chambers, A.F.7
-
80
-
-
34247269026
-
Genetic determinants of cancer metastasis
-
D.X. Nguyen, and J. Massague Genetic determinants of cancer metastasis Nat. Rev. Genet. 8 2007 341 352
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 341-352
-
-
Nguyen, D.X.1
Massague, J.2
-
81
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
D.X. Nguyen, A.C. Chiang, X.H. Zhang, J.Y. Kim, M.G. Kris, M. Ladanyi, W.L. Gerald, and J. Massagué WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis Cell 138 2009 51 62
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
Chiang, A.C.2
Zhang, X.H.3
Kim, J.Y.4
Kris, M.G.5
Ladanyi, M.6
Gerald, W.L.7
Massagué, J.8
-
82
-
-
0017617796
-
Hormonal control of growth and progression in tumors of Nb rats and a theory of action
-
R.L. Noble Hormonal control of growth and progression in tumors of Nb rats and a theory of action Cancer Res. 37 1977 82 94
-
(1977)
Cancer Res.
, vol.37
, pp. 82-94
-
-
Noble, R.L.1
-
83
-
-
33746807641
-
Is cancer a disease of self-seeding?
-
L. Norton, and J. Massagué Is cancer a disease of self-seeding? Nat. Med. 12 2006 875 878
-
(2006)
Nat. Med.
, vol.12
, pp. 875-878
-
-
Norton, L.1
Massagué, J.2
-
84
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
P.C. Nowell The clonal evolution of tumor cell populations Science 194 1976 23 28
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
85
-
-
84859073482
-
Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells
-
P. Nummela, J. Lammi, J. Soikkeli, O. Saksela, P. Laakkonen, and E. Hölttä Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells Am. J. Pathol. 180 2012 1663 1674
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 1663-1674
-
-
Nummela, P.1
Lammi, J.2
Soikkeli, J.3
Saksela, O.4
Laakkonen, P.5
Hölttä, E.6
-
86
-
-
20144379162
-
Endogenous inhibitors of angiogenesis
-
P. Nyberg, L. Xie, and R. Kalluri Endogenous inhibitors of angiogenesis Cancer Res. 65 2005 3967 3979
-
(2005)
Cancer Res.
, vol.65
, pp. 3967-3979
-
-
Nyberg, P.1
Xie, L.2
Kalluri, R.3
-
87
-
-
80053160728
-
VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization
-
J.T. O'Connell, H. Sugimoto, V.G. Cooke, B.A. MacDonald, A.I. Mehta, V.S. LeBleu, R. Dewar, R.M. Rocha, R.R. Brentani, and M.B. Resnick VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization Proc. Natl. Acad. Sci. USA 108 2011 16002 16007
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16002-16007
-
-
O'Connell, J.T.1
Sugimoto, H.2
Cooke, V.G.3
Macdonald, B.A.4
Mehta, A.I.5
Lebleu, V.S.6
Dewar, R.7
Rocha, R.M.8
Brentani, R.R.9
Resnick, M.B.10
-
88
-
-
84870816403
-
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1
-
O.H. Ocaña, R. Córcoles, A. Fabra, G. Moreno-Bueno, H. Acloque, S. Vega, A. Barrallo-Gimeno, A. Cano, and M.A. Nieto Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1 Cancer Cell 22 2012 709 724
-
(2012)
Cancer Cell
, vol.22
, pp. 709-724
-
-
Ocaña, O.H.1
Córcoles, R.2
Fabra, A.3
Moreno-Bueno, G.4
Acloque, H.5
Vega, S.6
Barrallo-Gimeno, A.7
Cano, A.8
Nieto, M.A.9
-
89
-
-
79960117895
-
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
-
T. Oskarsson, S. Acharyya, X.H. Zhang, S. Vanharanta, S.F. Tavazoie, P.G. Morris, R.J. Downey, K. Manova-Todorova, E. Brogi, and J. Massagué Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs Nat. Med. 17 2011 867 874
-
(2011)
Nat. Med.
, vol.17
, pp. 867-874
-
-
Oskarsson, T.1
Acharyya, S.2
Zhang, X.H.3
Vanharanta, S.4
Tavazoie, S.F.5
Morris, P.G.6
Downey, R.J.7
Manova-Todorova, K.8
Brogi, E.9
Massagué, J.10
-
90
-
-
77956641496
-
A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer
-
R. Pang, W.L. Law, A.C. Chu, J.T. Poon, C.S. Lam, A.K. Chow, L. Ng, L.W. Cheung, X.R. Lan, and H.Y. Lan A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer Cell Stem Cell 6 2010 603 615
-
(2010)
Cell Stem Cell
, vol.6
, pp. 603-615
-
-
Pang, R.1
Law, W.L.2
Chu, A.C.3
Poon, J.T.4
Lam, C.S.5
Chow, A.K.6
Ng, L.7
Cheung, L.W.8
Lan, X.R.9
Lan, H.Y.10
-
91
-
-
42649100970
-
Detection, clinical relevance and specific biological properties of disseminating tumour cells
-
K. Pantel, R.H. Brakenhoff, and B. Brandt Detection, clinical relevance and specific biological properties of disseminating tumour cells Nat. Rev. Cancer 8 2008 329 340
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 329-340
-
-
Pantel, K.1
Brakenhoff, R.H.2
Brandt, B.3
-
92
-
-
84870052886
-
Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis
-
N. Pencheva, H. Tran, C. Buss, D. Huh, M. Drobnjak, K. Busam, and S.F. Tavazoie Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis Cell 151 2012 1068 1082
-
(2012)
Cell
, vol.151
, pp. 1068-1082
-
-
Pencheva, N.1
Tran, H.2
Buss, C.3
Huh, D.4
Drobnjak, M.5
Busam, K.6
Tavazoie, S.F.7
-
93
-
-
84855813448
-
A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
-
K.J. Png, N. Halberg, M. Yoshida, and S.F. Tavazoie A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells Nature 481 2012 190 194
-
(2012)
Nature
, vol.481
, pp. 190-194
-
-
Png, K.J.1
Halberg, N.2
Yoshida, M.3
Tavazoie, S.F.4
-
94
-
-
52949139787
-
Seeding and propagation of untransformed mouse mammary cells in the lung
-
K. Podsypanina, Y.C. Du, M. Jechlinger, L.J. Beverly, D. Hambardzumyan, and H. Varmus Seeding and propagation of untransformed mouse mammary cells in the lung Science 321 2008 1841 1844
-
(2008)
Science
, vol.321
, pp. 1841-1844
-
-
Podsypanina, K.1
Du, Y.C.2
Jechlinger, M.3
Beverly, L.J.4
Hambardzumyan, D.5
Varmus, H.6
-
95
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
K. Polyak, and R.A. Weinberg Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits Nat. Rev. Cancer 9 2009 265 273
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
96
-
-
63049121364
-
The metastatic niche: Adapting the foreign soil
-
B. Psaila, and D. Lyden The metastatic niche: adapting the foreign soil Nat. Rev. Cancer 9 2009 285 293
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 285-293
-
-
Psaila, B.1
Lyden, D.2
-
97
-
-
79954533158
-
Shifting the equilibrium in cancer immunoediting: From tumor tolerance to eradication
-
S.A. Quezada, K.S. Peggs, T.R. Simpson, and J.P. Allison Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication Immunol. Rev. 241 2011 104 118
-
(2011)
Immunol. Rev.
, vol.241
, pp. 104-118
-
-
Quezada, S.A.1
Peggs, K.S.2
Simpson, T.R.3
Allison, J.P.4
-
98
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
E. Quintana, M. Shackleton, M.S. Sabel, D.R. Fullen, T.M. Johnson, and S.J. Morrison Efficient tumour formation by single human melanoma cells Nature 456 2008 593 598
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
99
-
-
34047111239
-
Cancer dormancy: Lessons from a B cell lymphoma and adenocarcinoma of the prostate
-
R. Rabinovsky, J.W. Uhr, E.S. Vitetta, and E. Yefenof Cancer dormancy: lessons from a B cell lymphoma and adenocarcinoma of the prostate Adv. Cancer Res. 97 2007 189 202
-
(2007)
Adv. Cancer Res.
, vol.97
, pp. 189-202
-
-
Rabinovsky, R.1
Uhr, J.W.2
Vitetta, E.S.3
Yefenof, E.4
-
100
-
-
32944478891
-
Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells
-
A.C. Ranganathan, L. Zhang, A.P. Adam, and J.A. Aguirre-Ghiso Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells Cancer Res. 66 2006 1702 1711
-
(2006)
Cancer Res.
, vol.66
, pp. 1702-1711
-
-
Ranganathan, A.C.1
Zhang, L.2
Adam, A.P.3
Aguirre-Ghiso, J.A.4
-
101
-
-
84873488509
-
The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis
-
M. Reichert, S. Takano, J. von Burstin, S.B. Kim, J.S. Lee, K. Ihida-Stansbury, C. Hahn, S. Heeg, G. Schneider, and A.D. Rhim The Prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis Genes Dev. 27 2013 288 300
-
(2013)
Genes Dev.
, vol.27
, pp. 288-300
-
-
Reichert, M.1
Takano, S.2
Von Burstin, J.3
Kim, S.B.4
Lee, J.S.5
Ihida-Stansbury, K.6
Hahn, C.7
Heeg, S.8
Schneider, G.9
Rhim, A.D.10
-
102
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
T. Reya, S.J. Morrison, M.F. Clarke, and I.L. Weissman Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
103
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
A.D. Rhim, E.T. Mirek, N.M. Aiello, A. Maitra, J.M. Bailey, F. McAllister, M. Reichert, G.L. Beatty, A.K. Rustgi, and R.H. Vonderheide EMT and dissemination precede pancreatic tumor formation Cell 148 2012 349 361
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
-
104
-
-
0036488496
-
Specialization of tumour vasculature
-
E. Ruoslahti Specialization of tumour vasculature Nat. Rev. Cancer 2 2002 83 90
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
-
105
-
-
79958735965
-
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth
-
M.S. Samuel, J.I. Lopez, E.J. McGhee, D.R. Croft, D. Strachan, P. Timpson, J. Munro, E. Schröder, J. Zhou, and V.G. Brunton Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth Cancer Cell 19 2011 776 791
-
(2011)
Cancer Cell
, vol.19
, pp. 776-791
-
-
Samuel, M.S.1
Lopez, J.I.2
McGhee, E.J.3
Croft, D.R.4
Strachan, D.5
Timpson, P.6
Munro, J.7
Schröder, E.8
Zhou, J.9
Brunton, V.G.10
-
106
-
-
24944534497
-
Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer
-
J.A. Schardt, M. Meyer, C.H. Hartmann, F. Schubert, O. Schmidt-Kittler, C. Fuhrmann, B. Polzer, M. Petronio, R. Eils, and C.A. Klein Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer Cancer Cell 8 2005 227 239
-
(2005)
Cancer Cell
, vol.8
, pp. 227-239
-
-
Schardt, J.A.1
Meyer, M.2
Hartmann, C.H.3
Schubert, F.4
Schmidt-Kittler, O.5
Fuhrmann, C.6
Polzer, B.7
Petronio, M.8
Eils, R.9
Klein, C.A.10
-
107
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
C. Scheel, E.N. Eaton, S.H. Li, C.L. Chaffer, F. Reinhardt, K.J. Kah, G. Bell, W. Guo, J. Rubin, A.L. Richardson, and R.A. Weinberg Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast Cell 145 2011 926 940
-
(2011)
Cell
, vol.145
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
Kah, K.J.6
Bell, G.7
Guo, W.8
Rubin, J.9
Richardson, A.L.10
Weinberg, R.A.11
-
108
-
-
84864854371
-
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas
-
A.G. Schepers, H.J. Snippert, D.E. Stange, M. van den Born, J.H. van Es, M. van de Wetering, and H. Clevers Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas Science 337 2012 730 735
-
(2012)
Science
, vol.337
, pp. 730-735
-
-
Schepers, A.G.1
Snippert, H.J.2
Stange, D.E.3
Van Den Born, M.4
Van Es, J.H.5
Van De Wetering, M.6
Clevers, H.7
-
109
-
-
48749105093
-
ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
-
D.M. Schewe, and J.A. Aguirre-Ghiso ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo Proc. Natl. Acad. Sci. USA 105 2008 10519 10524
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10519-10524
-
-
Schewe, D.M.1
Aguirre-Ghiso, J.A.2
-
110
-
-
34547743433
-
Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas
-
C. Schindlbeck, T. Kampik, W. Janni, B. Rack, U. Jeschke, S. Krajewski, H. Sommer, and K. Friese Prognostic relevance of disseminated tumor cells in the bone marrow and biological factors of 265 primary breast carcinomas Breast Cancer Res. 7 2005 R1174 R1185
-
(2005)
Breast Cancer Res.
, vol.7
-
-
Schindlbeck, C.1
Kampik, T.2
Janni, W.3
Rack, B.4
Jeschke, U.5
Krajewski, S.6
Sommer, H.7
Friese, K.8
-
111
-
-
0025236989
-
Epithelial tumor cells in bone marrow of patients with colorectal cancer: Immunocytochemical detection, phenotypic characterization, and prognostic significance
-
G. Schlimok, I. Funke, B. Bock, B. Schweiberer, J. Witte, and G. Riethmüller Epithelial tumor cells in bone marrow of patients with colorectal cancer: immunocytochemical detection, phenotypic characterization, and prognostic significance J. Clin. Oncol. 8 1990 831 837
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 831-837
-
-
Schlimok, G.1
Funke, I.2
Bock, B.3
Schweiberer, B.4
Witte, J.5
Riethmüller, G.6
-
112
-
-
0038271868
-
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
-
O. Schmidt-Kittler, T. Ragg, A. Daskalakis, M. Granzow, A. Ahr, T.J. Blankenstein, M. Kaufmann, J. Diebold, H. Arnholdt, and P. Muller From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression Proc. Natl. Acad. Sci. USA 100 2003 7737 7742
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 7737-7742
-
-
Schmidt-Kittler, O.1
Ragg, T.2
Daskalakis, A.3
Granzow, M.4
Ahr, A.5
Blankenstein, T.J.6
Kaufmann, M.7
Diebold, J.8
Arnholdt, H.9
Muller, P.10
-
113
-
-
84872600554
-
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
-
S. Schwitalla, A.A. Fingerle, P. Cammareri, T. Nebelsiek, S.I. Göktuna, P.K. Ziegler, O. Canli, J. Heijmans, D.J. Huels, and G. Moreaux Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties Cell 152 2013 25 38
-
(2013)
Cell
, vol.152
, pp. 25-38
-
-
Schwitalla, S.1
Fingerle, A.A.2
Cammareri, P.3
Nebelsiek, T.4
Göktuna, S.I.5
Ziegler, P.K.6
Canli, O.7
Heijmans, J.8
Huels, D.J.9
Moreaux, G.10
-
114
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
N. Sethi, X. Dai, C.G. Winter, and Y. Kang Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells Cancer Cell 19 2011 192 205
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
115
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
C.M. Shachaf, A.M. Kopelman, C. Arvanitis, A. Karlsson, S. Beer, S. Mandl, M.H. Bachmann, A.D. Borowsky, B. Ruebner, and R.D. Cardiff MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer Nature 431 2004 1112 1117
-
(2004)
Nature
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
Karlsson, A.4
Beer, S.5
Mandl, S.6
Bachmann, M.H.7
Borowsky, A.D.8
Ruebner, B.9
Cardiff, R.D.10
-
116
-
-
67649849871
-
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
-
T. Shibue, and R.A. Weinberg Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs Proc. Natl. Acad. Sci. USA 106 2009 10290 10295
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 10290-10295
-
-
Shibue, T.1
Weinberg, R.A.2
-
117
-
-
84866242179
-
The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions
-
T. Shibue, M.W. Brooks, M.F. Inan, F. Reinhardt, and R.A. Weinberg The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions Cancer Discov. 2 2012 706 721
-
(2012)
Cancer Discov.
, vol.2
, pp. 706-721
-
-
Shibue, T.1
Brooks, M.W.2
Inan, M.F.3
Reinhardt, F.4
Weinberg, R.A.5
-
118
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Y. Shimono, M. Zabala, R.W. Cho, N. Lobo, P. Dalerba, D. Qian, M. Diehn, H. Liu, S.P. Panula, and E. Chiao Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells Cell 138 2009 592 603
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
Diehn, M.7
Liu, H.8
Panula, S.P.9
Chiao, E.10
-
119
-
-
44849114353
-
Subtypes of breast cancer show preferential site of relapse
-
M. Smid, Y. Wang, Y. Zhang, A.M. Sieuwerts, J. Yu, J.G. Klijn, J.A. Foekens, and J.W. Martens Subtypes of breast cancer show preferential site of relapse Cancer Res. 68 2008 3108 3114
-
(2008)
Cancer Res.
, vol.68
, pp. 3108-3114
-
-
Smid, M.1
Wang, Y.2
Zhang, Y.3
Sieuwerts, A.M.4
Yu, J.5
Klijn, J.G.6
Foekens, J.A.7
Martens, J.W.8
-
120
-
-
36749090553
-
Location, location, location: The cancer stem cell niche
-
J.B. Sneddon, and Z. Werb Location, location, location: the cancer stem cell niche Cell Stem Cell 1 2007 607 611
-
(2007)
Cell Stem Cell
, vol.1
, pp. 607-611
-
-
Sneddon, J.B.1
Werb, Z.2
-
121
-
-
77955268790
-
Transmission of donor melanoma by organ transplantation
-
D.C. Strauss, and J.M. Thomas Transmission of donor melanoma by organ transplantation Lancet Oncol. 11 2010 790 796
-
(2010)
Lancet Oncol.
, vol.11
, pp. 790-796
-
-
Strauss, D.C.1
Thomas, J.M.2
-
122
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
S.F. Tavazoie, C. Alarcón, T. Oskarsson, D. Padua, Q. Wang, P.D. Bos, W.L. Gerald, and J. Massagué Endogenous human microRNAs that suppress breast cancer metastasis Nature 451 2008 147 152
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcón, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
Gerald, W.L.7
Massagué, J.8
-
123
-
-
84874908195
-
Modeling boundary conditions for balanced proliferation in metastatic latency
-
D.P. Taylor, J.Z. Wells, A. Savol, C. Chennubhotla, and A. Wells Modeling boundary conditions for balanced proliferation in metastatic latency Clin. Cancer Res. 19 2013 1063 1070
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 1063-1070
-
-
Taylor, D.P.1
Wells, J.Z.2
Savol, A.3
Chennubhotla, C.4
Wells, A.5
-
124
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
J.P. Thiery, H. Acloque, R.Y. Huang, and M.A. Nieto Epithelial- mesenchymal transitions in development and disease Cell 139 2009 871 890
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
125
-
-
84870845421
-
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
-
J.H. Tsai, J.L. Donaher, D.A. Murphy, S. Chau, and J. Yang Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis Cancer Cell 22 2012 725 736
-
(2012)
Cancer Cell
, vol.22
, pp. 725-736
-
-
Tsai, J.H.1
Donaher, J.L.2
Murphy, D.A.3
Chau, S.4
Yang, J.5
-
126
-
-
0030902368
-
Ultra-late recurrence (15 years or longer) of cutaneous melanoma
-
H. Tsao, A.B. Cosimi, and A.J. Sober Ultra-late recurrence (15 years or longer) of cutaneous melanoma Cancer 79 1997 2361 2370
-
(1997)
Cancer
, vol.79
, pp. 2361-2370
-
-
Tsao, H.1
Cosimi, A.B.2
Sober, A.J.3
-
127
-
-
80054686286
-
Tumor metastasis: Molecular insights and evolving paradigms
-
S. Valastyan, and R.A. Weinberg Tumor metastasis: molecular insights and evolving paradigms Cell 147 2011 275 292
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
128
-
-
84876817355
-
Beyond TGFβ: Roles of other TGFβ superfamily members in cancer
-
L.M. Wakefield, and C.S. Hill Beyond TGFβ: roles of other TGFβ superfamily members in cancer Nat. Rev. Cancer 13 2013 328 341
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 328-341
-
-
Wakefield, L.M.1
Hill, C.S.2
-
129
-
-
52049093659
-
The many faces of tumor dormancy
-
R.A. Weinberg The many faces of tumor dormancy APMIS 116 2008 548 551
-
(2008)
APMIS
, vol.116
, pp. 548-551
-
-
Weinberg, R.A.1
-
130
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
U. Wellner, J. Schubert, U.C. Burk, O. Schmalhofer, F. Zhu, A. Sonntag, B. Waldvogel, C. Vannier, D. Darling, and A. zur Hausen The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs Nat. Cell Biol. 11 2009 1487 1495
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
Waldvogel, B.7
Vannier, C.8
Darling, D.9
Zur Hausen, A.10
-
131
-
-
0025734512
-
A prolactin-dependent, metastasising rat mammary carcinoma as a model for endocrine-related tumour dormancy
-
J.H. Wijsman, C.J. Cornelisse, R. Keijzer, C.J. van de Velde, and J.H. van Dierendonck A prolactin-dependent, metastasising rat mammary carcinoma as a model for endocrine-related tumour dormancy Br. J. Cancer 64 1991 463 468
-
(1991)
Br. J. Cancer
, vol.64
, pp. 463-468
-
-
Wijsman, J.H.1
Cornelisse, C.J.2
Keijzer, R.3
Van De Velde, C.J.4
Van Dierendonck, J.H.5
-
132
-
-
79955584983
-
Suppression of lung adenocarcinoma progression by Nkx2-1
-
M.M. Winslow, T.L. Dayton, R.G. Verhaak, C. Kim-Kiselak, E.L. Snyder, D.M. Feldser, D.D. Hubbard, M.J. DuPage, C.A. Whittaker, and S. Hoersch Suppression of lung adenocarcinoma progression by Nkx2-1 Nature 473 2011 101 104
-
(2011)
Nature
, vol.473
, pp. 101-104
-
-
Winslow, M.M.1
Dayton, T.L.2
Verhaak, R.G.3
Kim-Kiselak, C.4
Snyder, E.L.5
Feldser, D.M.6
Hubbard, D.D.7
Dupage, M.J.8
Whittaker, C.A.9
Hoersch, S.10
-
133
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
D.J. Wong, H. Liu, T.W. Ridky, D. Cassarino, E. Segal, and H.Y. Chang Module map of stem cell genes guides creation of epithelial cancer stem cells Cell Stem Cell 2 2008 333 344
-
(2008)
Cell Stem Cell
, vol.2
, pp. 333-344
-
-
Wong, D.J.1
Liu, H.2
Ridky, T.W.3
Cassarino, D.4
Segal, E.5
Chang, H.Y.6
-
134
-
-
84862776537
-
Clonal selection drives genetic divergence of metastatic medulloblastoma
-
X. Wu, P.A. Northcott, A. Dubuc, A.J. Dupuy, D.J. Shih, H. Witt, S. Croul, E. Bouffet, D.W. Fults, and C.G. Eberhart Clonal selection drives genetic divergence of metastatic medulloblastoma Nature 482 2012 529 533
-
(2012)
Nature
, vol.482
, pp. 529-533
-
-
Wu, X.1
Northcott, P.A.2
Dubuc, A.3
Dupuy, A.J.4
Shih, D.J.5
Witt, H.6
Croul, S.7
Bouffet, E.8
Fults, D.W.9
Eberhart, C.G.10
-
135
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
S. Yachida, S. Jones, I. Bozic, T. Antal, R. Leary, B. Fu, M. Kamiyama, R.H. Hruban, J.R. Eshleman, and M.A. Nowak Distant metastasis occurs late during the genetic evolution of pancreatic cancer Nature 467 2010 1114 1117
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
Kamiyama, M.7
Hruban, R.H.8
Eshleman, J.R.9
Nowak, M.A.10
-
136
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
J. Yang, S.A. Mani, J.L. Donaher, S. Ramaswamy, R.A. Itzykson, C. Come, P. Savagner, I. Gitelman, A. Richardson, and R.A. Weinberg Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis Cell 117 2004 927 939
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
137
-
-
79952660821
-
Control of the embryonic stem cell state
-
R.A. Young Control of the embryonic stem cell state Cell 144 2011 940 954
-
(2011)
Cell
, vol.144
, pp. 940-954
-
-
Young, R.A.1
-
138
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
M. Yu, A. Bardia, B.S. Wittner, S.L. Stott, M.E. Smas, D.T. Ting, S.J. Isakoff, J.C. Ciciliano, M.N. Wells, and A.M. Shah Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition Science 339 2013 580 584
-
(2013)
Science
, vol.339
, pp. 580-584
-
-
Yu, M.1
Bardia, A.2
Wittner, B.S.3
Stott, S.L.4
Smas, M.E.5
Ting, D.T.6
Isakoff, S.J.7
Ciciliano, J.C.8
Wells, M.N.9
Shah, A.M.10
-
139
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
X.H. Zhang, Q. Wang, W. Gerald, C.A. Hudis, L. Norton, M. Smid, J.A. Foekens, and J. Massagué Latent bone metastasis in breast cancer tied to Src-dependent survival signals Cancer Cell 16 2009 67 78
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
Hudis, C.A.4
Norton, L.5
Smid, M.6
Foekens, J.A.7
Massagué, J.8
-
140
-
-
84877726784
-
The identification and characterization of breast cancer CTCs competent for brain metastasis
-
180ra148
-
L. Zhang, L.D. Ridgway, M.D. Wetzel, J. Ngo, W. Yin, D. Kumar, J.C. Goodman, M.D. Groves, and D. Marchetti The identification and characterization of breast cancer CTCs competent for brain metastasis Sci. Transl. Med. 5 2013 180ra148
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Zhang, L.1
Ridgway, L.D.2
Wetzel, M.D.3
Ngo, J.4
Yin, W.5
Kumar, D.6
Goodman, J.C.7
Groves, M.D.8
Marchetti, D.9
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