Diminished metastasis in tetraspanin CD151-knockout mice

Blood

Volumn 118, Issue 2, 2011, Pages 464-472

  Takeda, Yoshito ^a   Li, Qinglin ^a   Kazarov, Alexander R ^a   Epardaud, Mathieu ^a   Elpek, Kutlu ^a   Turley, Shannon J ^a   Hemler, Martin E ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD151 ANTIGEN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; IMMUNOSURVEILLANCE; KNOCKOUT MOUSE; LEWIS CARCINOMA; LUNG METASTASIS; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 79960478974     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-08-302240     Document Type: Article

References (50)

1. Bogenrieder T, Herlyn M. Axis of evil: molecular mechanisms of cancer metastasis. Oncogene. 2003;22(42):6524-6536. (Pubitemid 37372332)
2. Al-Mehdi AB, Tozawa K, Fisher AB, et al. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nat Med. 2000;6(1):100-102. (Pubitemid 30048535)
3. Berditchevski F, Odintsova E, Sawada S, Gilbert E. Expression of the palmitoylation-deficient CD151 weakens the association of alpha 3beta 1 integrin with the tetraspanin-enriched microdomains and affects integrin-dependent signalling. J Biol Chem. 2002;277(40):36991-37000.
4. Hemler ME. Tetraspanin proteins mediate cellular penetration, invasion and fusion events, and define a novel type of membrane microdomain. Ann Rev Cell Dev Biol. 2003;19:397-422. (Pubitemid 37487354)
5. Hemler ME. Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol. 2005;6(10):801-811.
6. Martin F, Roth DM, Jans DA, et al. Tetraspanins in viral infections: a fundamental role in viral biology? J Virol. 2005;79(17):10839-10851. (Pubitemid 41170627)
7. Levy S, Shoham T. Protein-protein interactions in the tetraspanin web. Physiology (Bethesda). 2005;20:218-224.
8. Zöller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat Rev Cancer. 2009;9(1):40-55.
9. Ikeyama S, Koyama M, Yamaoko M, Sasada R, Miyake M. Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. J Exp Med. 1993;177(5):1231-1237. (Pubitemid 23117114)
10. Tonoli H, Barrett JC. CD82 metastasis suppressor gene: a potential target for new therapeutics? Trends Mol Med. 2005;11(12):563-570. (Pubitemid 41713998)
11. Claas C, Seiter S, Claas A, et al. Association between rat homologue of CO-029, a metastasis-associated tetraspanin molecule and consumption coagulopathy. J Cell Biol. 1998;141(1):267-280. (Pubitemid 28182657)
12. Testa JE, Brooks PC, Lin JM, Quigley JP. Eukaryotic expression cloning with an antimetastatic monoclonal antibody identifies a tetraspanin (PETA-3/CD151) as an effector of human tumor cell migration and metastasis. Cancer Res. 1999;59(15):3812-3820. (Pubitemid 29381891)
13. Zijlstra A, Lewis J, Degryse B, Stuhlmann H, Quigley JP. The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell. 2008;13(3):221-234. (Pubitemid 351318371)
14. Sadej R, Romanska H, Kavanagh D, et al. Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis. Cancer Res. 2010;70(14):6059-6070.
15. Yauch RL, Berditchevski F, Harler MB, Reichner J, Hemler ME. Highly stoichiometric, stable and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase and may regulate cell migration. Mol Biol Cell. 1998;9(10):2751-2765. (Pubitemid 28473659)
16. Sterk LM, Geuijen CA, van Den Berg JG, et al. Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo. J Cell Sci. 2002;115(pt 6):1161-1173. (Pubitemid 34272481)
17. Stipp CS, Hemler ME. Transmembrane-4-superfamily proteins CD151 and CD81 associate with alpha 3 beta 1 integrin, and selectively contribute to alpha 3 beta 1-dependent neurite outgrowth. J Cell Sci. 2000;113(pt 11):1871-1882. (Pubitemid 30386491)
18. Yáez-Mó M, Alfranca A, Cabañas C, et al. Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3beta1 integrin localized at endothelial lateral junctions. J Cell Biol. 1998;141(3):791-804. (Pubitemid 28217922)
19. Sincock PM, Fitter S, Parton RG, et al. PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. J Cell Sci. 1999;112(pt 6):833-844. (Pubitemid 29179316)
20. Lammerding J, Kazarov AR, Huang H, Lee RT, Hemler ME. Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening. Proc Natl Acad Sci U S A. 2003;100(13):7616-7621. (Pubitemid 36760018)
21. Winterwood NE, Varzavand A, Meland MN, Ashman LK, Stipp CS. A critical role for tetraspanin CD151 in alpha3beta1 and alpha6beta4 integrin-dependent tumor cell functions on laminin-5. Mol Biol Cell. 2006;17(6):2707-2721. (Pubitemid 43825507)
22. Takeda Y, Kazarov AR, Butterfield CE, et al. Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro. Blood. 2007;109(4):1524-1532. (Pubitemid 46239585)
23. Dlugosz AA, Glick AB, Tennenbaum T, Weinberg WC, Yuspa SH. Isolation and utilization of epidermal keratinocytes for oncogene research. Methods Enzymol. 1995;254:3-20.
24. Ye Z, Shi M, Chan T, et al. Engineered CD8(+) cytotoxic T cells with fiber-modified adenovirus-mediated TNF-alpha gene transfection counteract immunosuppressive interleukin-10-secreting lung metastasis and solid tumors. Cancer Gene Ther. 2007;14(7):661-675. (Pubitemid 46912034)
25. Grundy MA, Zhang T, Sentman CL. NK cells rapidly remove B16F10 tumor cells in a perforin and interferon-gamma independent manner in vivo. Cancer Immunol Immunother. 2007;56(8):1153-1161. (Pubitemid 46763930)
26. Sheng KC, van Spriel AB, Gartlan KH, et al. Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC. Eur J Immunol. 2009;39(1):50-55.
27. Barnhill RL. The biology of melanoma micrometastases. Recent Results Cancer Res. 2001;158:3-13.
28. Cowin AJ, Adams D, Geary SM, et al. Wound healing is defective in mice lacking tetraspanin CD151. J Invest Dermatol. 2006;126(3):680-689. (Pubitemid 43255660)
29. Lee TH, Avraham HK, Jiang S, Avraham S. Vascular endothelial growth factor modulates the transendothelial migration of MDA-MB-231 breast cancer cells through regulation of brain microvascular endothelial cell permeability. J Biol Chem. 2003;278(7):5277-5284. (Pubitemid 36801042)
30. Dvorak HF. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol. 2002;20(21):4368-4380. (Pubitemid 35266299)
31. Zachary I. VEGF signalling: integration and multi-tasking in endothelial cell biology. Biochem Soc Trans. 2003;31(pt 6):1171-1177. (Pubitemid 38030933)
32. Issbrücker K, Marti HH, Hippenstiel S, et al. p38 MAP kinase - a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J. 2003;17(2):262-264.
33. Nakashima Y, Yano M, Kobayashi Y, et al. Endostatin gene therapy on murine lung metastases model utilizing cationic vector-mediated intravenous gene delivery. Gene Ther. 2003;10(2):123-130. (Pubitemid 36582584)
34. Barreiro O, Yanez-Mo M, Sala-Valdes M, et al. Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood. 2005;105(7):2852-2861. (Pubitemid 40446279)
35. Engbring JA, Kleinman HK. The basement membrane matrix in malignancy. J Pathol. 2003;200(4):465-470.
36. Oka H, Emori Y, Hayashi Y, Nomoto K. Breakdown of Th cell immune responses and steroidogenic CYP11A1 expression in CD4+ T cells in a murine model implanted with B16 melanoma. Cell Immunol. 2000;206(1):7-15. (Pubitemid 32105806)
37. Paget C, Mallevaey T, Speak AO, et al. Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity. 2007;27(4):597-609. (Pubitemid 47628833)
38. Wright MD, Geary SM, Fitter S, et al. Characterization of mice lacking the tetraspanin superfamily member CD151. Mol Cell Biol. 2004;24(13):5978-5988. (Pubitemid 38787980)
39. Yang XH, Flores LM, Li Q, et al. Disruption of laminin-integrin-CD151- focal adhesion kinase axis sensitizes breast cancer cells to ErbB2 antagonists. Cancer Res. 2010;70(6):2256-2263.
40. Yang XH, Richardson AL, Torres-Arzayus MI, et al. CD151 accelerates breast cancer by regulating alpha 6 integrin functions, signaling, and molecular organization. Cancer Res. 2008;68(9):3204-3213.
41. Barreiro O, Zamai M, Yanez-Mo M, et al. Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms. J Cell Biol. 2008;183(3):527-542.
42. Rebhun RB, Cheng H, Gershenwald JE, et al. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia. 2010;12(2):173-182.
43. Vitolo D, Ciocci L, Deriu G, et al. Laminin alpha2 chain-positive vessels and epidermal growth factor in lung neuroendocrine carcinoma: a model of a novel cooperative role of laminin-2 and epidermal growth factor in vessel neoplastic invasion and metastasis. Am J Pathol. 2006;168(3):991-1003. (Pubitemid 43327750)
44. Stipp CS. Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets. Expert Rev Mol Med. 2010;12:e3.
45. Weis SM, Lindquist JN, Barnes LA, et al. Cooperation between VEGF and beta3 integrin during cardiac vascular development. Blood. 2007;109(5):1962- 1970. (Pubitemid 46348193)
46. Shi GM, Ke AW, Zhou J, et al. CD151 modulates expression of matrix metalloproteinase 9 and promotes neoangiogenesis and progression of hepatocellular carcinoma. Hepatology. 2010;52(1):183-196.
47. Sugiura T, Berditchevski F. Function of α3β1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2). J Cell Biol. 1999;146(6):1375-1389. (Pubitemid 29477702)
48. Itoh T, Tanioka M, Yoshida H, et al. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. Cancer Res. 1998;58(5):1048-1051. (Pubitemid 28182477)
49. Hiratsuka S, Nakamura K, Iwai S, et al. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell. 2002;2(4):289-300. (Pubitemid 41043963)
50. Camerer E, Qazi AA, Duong DN, et al. Platelets, protease-activated receptors, and fibrinogen in hematogenous metastasis. Blood. 2004;104(2):397-401. (Pubitemid 38900020)