메뉴 건너뛰기




Volumn 168, Issue 2, 2015, Pages 191-200

Mesenchymal stromal cells and chronic inflammatory bowel disease

Author keywords

Cell therapy; Crohn's disease; Inflammatory bowel disease; Mesenchymal stromal cells; Regenerative medicine; Translational research; Ulcerative colitis

Indexed keywords

CD4 ANTIGEN; CD45RB ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 22; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

EID: 84949623553     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2015.06.018     Document Type: Article
Times cited : (19)

References (118)
  • 2
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham C., Cho J.H. Inflammatory bowel disease. N. Engl. J. Med. 2009, 361:2066-2078.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 4
    • 34248136340 scopus 로고    scopus 로고
    • Inflammatory bowel disease: clinical aspects and established and evolving therapies
    • Baumgart D.C., Sandborn W.J. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007, 369:1641-1657.
    • (2007) Lancet , vol.369 , pp. 1641-1657
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 5
    • 84920675807 scopus 로고    scopus 로고
    • Treatment of IBD: where we are and where we are going
    • Bernstein C.N. Treatment of IBD: where we are and where we are going. Am. J. Gastroenterol. 2015, 110:114-126.
    • (2015) Am. J. Gastroenterol. , vol.110 , pp. 114-126
    • Bernstein, C.N.1
  • 7
    • 84857032992 scopus 로고    scopus 로고
    • Mesenchymal stromal cell therapy: a revolution in regenerative medicine?
    • Bernardo M.E., Pagliara D., Locatelli F. Mesenchymal stromal cell therapy: a revolution in regenerative medicine?. Bone Marrow Transplant. 2012, 47:164-171.
    • (2012) Bone Marrow Transplant. , vol.47 , pp. 164-171
    • Bernardo, M.E.1    Pagliara, D.2    Locatelli, F.3
  • 8
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • Friedenstein A.J., Chailakhyan R.K., Latsinik N.V., Panasyuk A.F., Keiliss-Borok I.V. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation 1974, 17:331-340.
    • (1974) Transplantation , vol.17 , pp. 331-340
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3    Panasyuk, A.F.4    Keiliss-Borok, I.V.5
  • 9
    • 0035889146 scopus 로고    scopus 로고
    • Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
    • Campagnoli C., Roberts I.A., Kumar S., Bennett P.R., Bellantuono I., Fisk N.M. Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood 2001, 98:2396-2402.
    • (2001) Blood , vol.98 , pp. 2396-2402
    • Campagnoli, C.1    Roberts, I.A.2    Kumar, S.3    Bennett, P.R.4    Bellantuono, I.5    Fisk, N.M.6
  • 10
    • 26444553353 scopus 로고    scopus 로고
    • Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?
    • Im G.I., Shin Y.W., Lee K.B. Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?. Osteoarthritis Cartilage/OARS, Osteoarthritis Res. Soc. 2005, 13:845-853.
    • (2005) Osteoarthritis Cartilage/OARS, Osteoarthritis Res. Soc. , vol.13 , pp. 845-853
    • Im, G.I.1    Shin, Y.W.2    Lee, K.B.3
  • 11
    • 1542286220 scopus 로고    scopus 로고
    • Mesenchymal stem cells: clinical applications and biological characterization
    • Barry F.P., Murphy J.M. Mesenchymal stem cells: clinical applications and biological characterization. Int. J. Biochem. Cell Biol. 2004, 36:568-584.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 568-584
    • Barry, F.P.1    Murphy, J.M.2
  • 13
    • 79958045747 scopus 로고    scopus 로고
    • The clinical use of human culture-expanded autologous bone marrow mesenchymal stem cells transplanted on platelet-rich fibrin glue in the treatment of articular cartilage defects: a pilot study and preliminary results
    • Haleem A.M., Singergy A.A., Sabry D., Atta H.M., Rashed L.A., Chu C.R., et al. The clinical use of human culture-expanded autologous bone marrow mesenchymal stem cells transplanted on platelet-rich fibrin glue in the treatment of articular cartilage defects: a pilot study and preliminary results. Cartilage 2010, 1:253-261.
    • (2010) Cartilage , vol.1 , pp. 253-261
    • Haleem, A.M.1    Singergy, A.A.2    Sabry, D.3    Atta, H.M.4    Rashed, L.A.5    Chu, C.R.6
  • 14
    • 34948892668 scopus 로고    scopus 로고
    • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation
    • Ball L.M., Bernardo M.E., Roelofs H., Lankester A., Cometa A., Egeler R.M., et al. Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation. Blood 2007, 110:2764-2767.
    • (2007) Blood , vol.110 , pp. 2764-2767
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3    Lankester, A.4    Cometa, A.5    Egeler, R.M.6
  • 15
    • 79951679002 scopus 로고    scopus 로고
    • Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation
    • Bernardo M.E., Ball L.M., Cometa A.M., Roelofs H., Zecca M., Avanzini M.A., et al. Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation. Bone Marrow Transplant. 2011, 46:200-207.
    • (2011) Bone Marrow Transplant. , vol.46 , pp. 200-207
    • Bernardo, M.E.1    Ball, L.M.2    Cometa, A.M.3    Roelofs, H.4    Zecca, M.5    Avanzini, M.A.6
  • 16
    • 84886404127 scopus 로고    scopus 로고
    • Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease
    • Ball L.M., Bernardo M.E., Roelofs H., van Tol M.J., Contoli B., Zwaginga J.J., et al. Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease. Br. J. Haematol. 2013, 163:501-509.
    • (2013) Br. J. Haematol. , vol.163 , pp. 501-509
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3    van Tol, M.J.4    Contoli, B.5    Zwaginga, J.J.6
  • 17
    • 78650071907 scopus 로고    scopus 로고
    • Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes
    • Jurewicz M., Yang S., Augello A., Godwin J.G., Moore R.F., Azzi J., et al. Congenic mesenchymal stem cell therapy reverses hyperglycemia in experimental type 1 diabetes. Diabetes 2010, 59:3139-3147.
    • (2010) Diabetes , vol.59 , pp. 3139-3147
    • Jurewicz, M.1    Yang, S.2    Augello, A.3    Godwin, J.G.4    Moore, R.F.5    Azzi, J.6
  • 18
    • 34249883938 scopus 로고    scopus 로고
    • Mesenchymal stem cells prevent progressive experimental renal failure but maldifferentiate into glomerular adipocytes
    • Kunter U., Rong S., Boor P., Eitner F., Muller-Newen G., Djuric Z., et al. Mesenchymal stem cells prevent progressive experimental renal failure but maldifferentiate into glomerular adipocytes. J. Am. Soc. Nephrol. 2007, 18:1754-1764.
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 1754-1764
    • Kunter, U.1    Rong, S.2    Boor, P.3    Eitner, F.4    Muller-Newen, G.5    Djuric, Z.6
  • 21
    • 33745187411 scopus 로고    scopus 로고
    • Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat
    • Honma T., Honmou O., Iihoshi S., Harada K., Houkin K., Hamada H., et al. Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp. Neurol. 2006, 199:56-66.
    • (2006) Exp. Neurol. , vol.199 , pp. 56-66
    • Honma, T.1    Honmou, O.2    Iihoshi, S.3    Harada, K.4    Houkin, K.5    Hamada, H.6
  • 22
    • 60449100851 scopus 로고    scopus 로고
    • Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses
    • Gonzalez M.A., Gonzalez-Rey E., Rico L., Buscher D., Delgado M. Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses. Gastroenterology 2009, 136:978-989.
    • (2009) Gastroenterology , vol.136 , pp. 978-989
    • Gonzalez, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Buscher, D.4    Delgado, M.5
  • 23
    • 34548610480 scopus 로고    scopus 로고
    • Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    • Gupta N., Su X., Popov B., Lee J.W., Serikov V., Matthay M.A. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J. Immunol. 2007, 179:1855-1863.
    • (2007) J. Immunol. , vol.179 , pp. 1855-1863
    • Gupta, N.1    Su, X.2    Popov, B.3    Lee, J.W.4    Serikov, V.5    Matthay, M.A.6
  • 24
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee R.H., Pulin A.A., Seo M.J., Kota D.J., Ylostalo J., Larson B.L., et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 2009, 5:54-63.
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3    Kota, D.J.4    Ylostalo, J.5    Larson, B.L.6
  • 27
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • Cho J.H. The genetics and immunopathogenesis of inflammatory bowel disease. Nat. Rev. Immunol. 2008, 8:458-466.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 28
    • 33846627302 scopus 로고    scopus 로고
    • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
    • Hampe J., Franke A., Rosenstiel P., Till A., Teuber M., Huse K., et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 2007, 39:207-211.
    • (2007) Nat. Genet. , vol.39 , pp. 207-211
    • Hampe, J.1    Franke, A.2    Rosenstiel, P.3    Till, A.4    Teuber, M.5    Huse, K.6
  • 29
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • Parkes M., Barrett J.C., Prescott N.J., Tremelling M., Anderson C.A., Fisher S.A., et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat. Genet. 2007, 39:830-832.
    • (2007) Nat. Genet. , vol.39 , pp. 830-832
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3    Tremelling, M.4    Anderson, C.A.5    Fisher, S.A.6
  • 30
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • Franke A., McGovern D.P., Barrett J.C., Wang K., Radford-Smith G.L., Ahmad T., et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet. 2010, 42:1118-1125.
    • (2010) Nat. Genet. , vol.42 , pp. 1118-1125
    • Franke, A.1    McGovern, D.P.2    Barrett, J.C.3    Wang, K.4    Radford-Smith, G.L.5    Ahmad, T.6
  • 31
    • 79955563439 scopus 로고    scopus 로고
    • Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases
    • Strober W., Fuss I.J. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011, 140:1756-1767.
    • (2011) Gastroenterology , vol.140 , pp. 1756-1767
    • Strober, W.1    Fuss, I.J.2
  • 32
    • 84869213229 scopus 로고    scopus 로고
    • Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease
    • Christophi G.P., Rong R., Holtzapple P.G., Massa P.T., Landas S.K. Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease. Inflamm. Bowel Dis. 2012, 18:2342-2356.
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 2342-2356
    • Christophi, G.P.1    Rong, R.2    Holtzapple, P.G.3    Massa, P.T.4    Landas, S.K.5
  • 33
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • Zhou L., Ivanov I.I., Spolski R., Min R., Shenderov K., Egawa T., et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 2007, 8:967-974.
    • (2007) Nat. Immunol. , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3    Min, R.4    Shenderov, K.5    Egawa, T.6
  • 34
    • 84860996207 scopus 로고    scopus 로고
    • Th17-related cytokines in inflammatory bowel diseases: friends or foes?
    • Monteleone I., Sarra M., Pallone F., Monteleone G. Th17-related cytokines in inflammatory bowel diseases: friends or foes?. Curr. Mol. Med. 2012, 12:592-597.
    • (2012) Curr. Mol. Med. , vol.12 , pp. 592-597
    • Monteleone, I.1    Sarra, M.2    Pallone, F.3    Monteleone, G.4
  • 36
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M., Glennie S., Dyson J., Scott D., Laylor R., Simpson E., et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003, 101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6
  • 37
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation
    • Tse W.T., Pendleton J.D., Beyer W.M., Egalka M.C., Guinan E.C. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 2003, 75:389-397.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 38
    • 84878401681 scopus 로고    scopus 로고
    • Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells
    • Luz-Crawford P., Kurte M., Bravo-Alegria J., Contreras R., Nova-Lamperti E., Tejedor G., et al. Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells. Stem Cell Res. Ther. 2013, 4:65.
    • (2013) Stem Cell Res. Ther. , vol.4 , pp. 65
    • Luz-Crawford, P.1    Kurte, M.2    Bravo-Alegria, J.3    Contreras, R.4    Nova-Lamperti, E.5    Tejedor, G.6
  • 39
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I., Ringden O., Sundberg B., Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003, 76:1208-1213.
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 40
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R., Zibert A., Laryea M., Gobel U., Daubener W., Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004, 103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 41
    • 36349017810 scopus 로고    scopus 로고
    • A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells
    • Chabannes D., Hill M., Merieau E., Rossignol J., Brion R., Soulillou J.P., et al. A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells. Blood 2007, 110:3691-3694.
    • (2007) Blood , vol.110 , pp. 3691-3694
    • Chabannes, D.1    Hill, M.2    Merieau, E.3    Rossignol, J.4    Brion, R.5    Soulillou, J.P.6
  • 42
    • 84883614526 scopus 로고    scopus 로고
    • Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages
    • Melief S.M., Schrama E., Brugman M.H., Tiemessen M.M., Hoogduijn M.J., Fibbe W.E., et al. Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages. Stem Cells 2013, 31:1980-1991.
    • (2013) Stem Cells , vol.31 , pp. 1980-1991
    • Melief, S.M.1    Schrama, E.2    Brugman, M.H.3    Tiemessen, M.M.4    Hoogduijn, M.J.5    Fibbe, W.E.6
  • 43
    • 84872168547 scopus 로고    scopus 로고
    • Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance?
    • Burr S.P., Dazzi F., Garden O.A. Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance?. Immunol. Cell Biol. 2013, 91:12-18.
    • (2013) Immunol. Cell Biol. , vol.91 , pp. 12-18
    • Burr, S.P.1    Dazzi, F.2    Garden, O.A.3
  • 44
    • 80053221596 scopus 로고    scopus 로고
    • Pretreatment with interferon-gamma enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis
    • Duijvestein M., Wildenberg M.E., Welling M.M., Hennink S., Molendijk I., van Zuylen V.L., et al. Pretreatment with interferon-gamma enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis. Stem Cells 2011, 29:1549-1558.
    • (2011) Stem Cells , vol.29 , pp. 1549-1558
    • Duijvestein, M.1    Wildenberg, M.E.2    Welling, M.M.3    Hennink, S.4    Molendijk, I.5    van Zuylen, V.L.6
  • 45
    • 80052487336 scopus 로고    scopus 로고
    • Mesenchymal stromal cell 'licensing': a multistep process
    • Krampera M. Mesenchymal stromal cell 'licensing': a multistep process. Leukemia 2011, 25:1408-1414.
    • (2011) Leukemia , vol.25 , pp. 1408-1414
    • Krampera, M.1
  • 46
    • 84885099905 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: sensors and switchers of inflammation
    • Bernardo M.E., Fibbe W.E. Mesenchymal stromal cells: sensors and switchers of inflammation. Cell Stem Cell 2013, 13:392-402.
    • (2013) Cell Stem Cell , vol.13 , pp. 392-402
    • Bernardo, M.E.1    Fibbe, W.E.2
  • 47
    • 84880278485 scopus 로고    scopus 로고
    • Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells
    • Nemoto Y., Kanai T., Takahara M., Oshima S., Nakamura T., Okamoto R., et al. Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells. Gut 2013, 62:1142-1152.
    • (2013) Gut , vol.62 , pp. 1142-1152
    • Nemoto, Y.1    Kanai, T.2    Takahara, M.3    Oshima, S.4    Nakamura, T.5    Okamoto, R.6
  • 48
    • 69249227552 scopus 로고    scopus 로고
    • MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2
    • Spaggiari G.M., Abdelrazik H., Becchetti F., Moretta L. MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. Blood 2009, 113:6576-6583.
    • (2009) Blood , vol.113 , pp. 6576-6583
    • Spaggiari, G.M.1    Abdelrazik, H.2    Becchetti, F.3    Moretta, L.4
  • 49
    • 84906545300 scopus 로고    scopus 로고
    • Umbilical cord-derived mesenchymal stem cells instruct dendritic cells to acquire tolerogenic phenotypes through the IL-6-mediated upregulation of SOCS1
    • Deng Y., Yi S., Wang G., Cheng J., Zhang Y., Chen W., et al. Umbilical cord-derived mesenchymal stem cells instruct dendritic cells to acquire tolerogenic phenotypes through the IL-6-mediated upregulation of SOCS1. Stem Cells Dev. 2014, 23:2080-2092.
    • (2014) Stem Cells Dev. , vol.23 , pp. 2080-2092
    • Deng, Y.1    Yi, S.2    Wang, G.3    Cheng, J.4    Zhang, Y.5    Chen, W.6
  • 50
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • Spaggiari G.M., Capobianco A., Becchetti S., Mingari M.C., Moretta L. Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 2006, 107:1484-1490.
    • (2006) Blood , vol.107 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 51
    • 38949183675 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2
    • Spaggiari G.M., Capobianco A., Abdelrazik H., Becchetti F., Mingari M.C., Moretta L. Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2. Blood 2008, 111:1327-1333.
    • (2008) Blood , vol.111 , pp. 1327-1333
    • Spaggiari, G.M.1    Capobianco, A.2    Abdelrazik, H.3    Becchetti, F.4    Mingari, M.C.5    Moretta, L.6
  • 52
    • 20844440562 scopus 로고    scopus 로고
    • Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
    • Togel F., Hu Z., Weiss K., Isaac J., Lange C., Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am. J. Physiol. Ren. Physiol. 2005, 289:F31-F42.
    • (2005) Am. J. Physiol. Ren. Physiol. , vol.289 , pp. F31-F42
    • Togel, F.1    Hu, Z.2    Weiss, K.3    Isaac, J.4    Lange, C.5    Westenfelder, C.6
  • 53
    • 84861574208 scopus 로고    scopus 로고
    • Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models
    • Bai L., Lennon D.P., Caplan A.I., DeChant A., Hecker J., Kranso J., et al. Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models. Nat. Neurosci. 2012, 15:862-870.
    • (2012) Nat. Neurosci. , vol.15 , pp. 862-870
    • Bai, L.1    Lennon, D.P.2    Caplan, A.I.3    DeChant, A.4    Hecker, J.5    Kranso, J.6
  • 54
    • 84908132425 scopus 로고    scopus 로고
    • Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications
    • Wang Y., Chen X., Cao W., Shi Y. Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications. Nat. Immunol. 2014, 15:1009-1016.
    • (2014) Nat. Immunol. , vol.15 , pp. 1009-1016
    • Wang, Y.1    Chen, X.2    Cao, W.3    Shi, Y.4
  • 55
    • 84886696817 scopus 로고    scopus 로고
    • Mesenchymal stem cells migration homing and tracking
    • Sohni A., Verfaillie C.M. Mesenchymal stem cells migration homing and tracking. Stem Cells Int. 2013, 2013:130763.
    • (2013) Stem Cells Int. , vol.2013 , pp. 130763
    • Sohni, A.1    Verfaillie, C.M.2
  • 56
    • 84872914245 scopus 로고    scopus 로고
    • Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
    • Eggenhofer E., Benseler V., Kroemer A., Popp F.C., Geissler E.K., Schlitt H.J., et al. Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion. Front. Immunol. 2012, 3:297.
    • (2012) Front. Immunol. , vol.3 , pp. 297
    • Eggenhofer, E.1    Benseler, V.2    Kroemer, A.3    Popp, F.C.4    Geissler, E.K.5    Schlitt, H.J.6
  • 57
    • 7244224904 scopus 로고    scopus 로고
    • A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow
    • Wynn R.F., Hart C.A., Corradi-Perini C., O'Neill L., Evans C.A., Wraith J.E., et al. A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 2004, 104:2643-2645.
    • (2004) Blood , vol.104 , pp. 2643-2645
    • Wynn, R.F.1    Hart, C.A.2    Corradi-Perini, C.3    O'Neill, L.4    Evans, C.A.5    Wraith, J.E.6
  • 58
    • 33845277598 scopus 로고    scopus 로고
    • Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells
    • Ruster B., Gottig S., Ludwig R.J., Bistrian R., Muller S., Seifried E., et al. Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. Blood 2006, 108:3938-3944.
    • (2006) Blood , vol.108 , pp. 3938-3944
    • Ruster, B.1    Gottig, S.2    Ludwig, R.J.3    Bistrian, R.4    Muller, S.5    Seifried, E.6
  • 59
    • 34247368028 scopus 로고    scopus 로고
    • MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines
    • Ries C., Egea V., Karow M., Kolb H., Jochum M., Neth P. MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines. Blood 2007, 109:4055-4063.
    • (2007) Blood , vol.109 , pp. 4055-4063
    • Ries, C.1    Egea, V.2    Karow, M.3    Kolb, H.4    Jochum, M.5    Neth, P.6
  • 60
    • 84928396323 scopus 로고    scopus 로고
    • Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease
    • Chinnadurai R., Ng S., Velu V., Galipeau J. Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease. World J. Gastroenterol. 2015, 21:4779-4787.
    • (2015) World J. Gastroenterol. , vol.21 , pp. 4779-4787
    • Chinnadurai, R.1    Ng, S.2    Velu, V.3    Galipeau, J.4
  • 61
    • 34347262689 scopus 로고    scopus 로고
    • Chemically induced mouse models of intestinal inflammation
    • Wirtz S., Neufert C., Weigmann B., Neurath M.F. Chemically induced mouse models of intestinal inflammation. Nat. Protoc. 2007, 2:541-546.
    • (2007) Nat. Protoc. , vol.2 , pp. 541-546
    • Wirtz, S.1    Neufert, C.2    Weigmann, B.3    Neurath, M.F.4
  • 63
  • 64
    • 10944253153 scopus 로고    scopus 로고
    • Oxazolone-induced colitis in BALB/C mice: a new method to evaluate the efficacy of therapeutic agents for ulcerative colitis
    • Kojima R., Kuroda S., Ohkishi T., Nakamaru K., Hatakeyama S. Oxazolone-induced colitis in BALB/C mice: a new method to evaluate the efficacy of therapeutic agents for ulcerative colitis. J. Pharmacol. Sci. 2004, 96:307-313.
    • (2004) J. Pharmacol. Sci. , vol.96 , pp. 307-313
    • Kojima, R.1    Kuroda, S.2    Ohkishi, T.3    Nakamaru, K.4    Hatakeyama, S.5
  • 65
    • 0028519015 scopus 로고
    • Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
    • Powrie F., Leach M.W., Mauze S., Menon S., Caddle L.B., Coffman R.L. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994, 1:553-562.
    • (1994) Immunity , vol.1 , pp. 553-562
    • Powrie, F.1    Leach, M.W.2    Mauze, S.3    Menon, S.4    Caddle, L.B.5    Coffman, R.L.6
  • 66
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells
    • Mottet C., Uhlig H.H., Powrie F. Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J. Immunol. 2003, 170:3939-3943.
    • (2003) J. Immunol. , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 67
    • 0033772055 scopus 로고    scopus 로고
    • Interleukin 10-deficient colitis: new similarities to human inflammatory bowel disease
    • Kennedy R.J., Hoper M., Deodhar K., Erwin P.J., Kirk S.J., Gardiner K.R. Interleukin 10-deficient colitis: new similarities to human inflammatory bowel disease. Br. J. Surg. 2000, 87:1346-1351.
    • (2000) Br. J. Surg. , vol.87 , pp. 1346-1351
    • Kennedy, R.J.1    Hoper, M.2    Deodhar, K.3    Erwin, P.J.4    Kirk, S.J.5    Gardiner, K.R.6
  • 68
    • 55749112995 scopus 로고    scopus 로고
    • Exogenous administration of mesenchymal stem cells ameliorates dextran sulfate sodium-induced colitis via anti-inflammatory action in damaged tissue in rats
    • Tanaka F., Tominaga K., Ochi M., Tanigawa T., Watanabe T., Fujiwara Y., et al. Exogenous administration of mesenchymal stem cells ameliorates dextran sulfate sodium-induced colitis via anti-inflammatory action in damaged tissue in rats. Life Sci. 2008, 83:771-779.
    • (2008) Life Sci. , vol.83 , pp. 771-779
    • Tanaka, F.1    Tominaga, K.2    Ochi, M.3    Tanigawa, T.4    Watanabe, T.5    Fujiwara, Y.6
  • 69
    • 47949120741 scopus 로고    scopus 로고
    • Topical implantation of mesenchymal stem cells has beneficial effects on healing of experimental colitis in rats
    • Hayashi Y., Tsuji S., Tsujii M., Nishida T., Ishii S., Iijima H., et al. Topical implantation of mesenchymal stem cells has beneficial effects on healing of experimental colitis in rats. J. Pharmacol. Exp. Ther. 2008, 326:523-531.
    • (2008) J. Pharmacol. Exp. Ther. , vol.326 , pp. 523-531
    • Hayashi, Y.1    Tsuji, S.2    Tsujii, M.3    Nishida, T.4    Ishii, S.5    Iijima, H.6
  • 70
    • 67651052481 scopus 로고    scopus 로고
    • Comparison of the population capacity of hematopoietic and mesenchymal stem cells in experimental colitis rat model
    • Wei Y., Nie Y., Lai J., Wan Y.J., Li Y. Comparison of the population capacity of hematopoietic and mesenchymal stem cells in experimental colitis rat model. Transplantation 2009, 88:42-48.
    • (2009) Transplantation , vol.88 , pp. 42-48
    • Wei, Y.1    Nie, Y.2    Lai, J.3    Wan, Y.J.4    Li, Y.5
  • 71
    • 67650093720 scopus 로고    scopus 로고
    • Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity
    • Yabana T., Arimura Y., Tanaka H., Goto A., Hosokawa M., Nagaishi K., et al. Enhancing epithelial engraftment of rat mesenchymal stem cells restores epithelial barrier integrity. J. Pathol. 2009, 218:350-359.
    • (2009) J. Pathol. , vol.218 , pp. 350-359
    • Yabana, T.1    Arimura, Y.2    Tanaka, H.3    Goto, A.4    Hosokawa, M.5    Nagaishi, K.6
  • 72
    • 76249084930 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis
    • Zhang Q., Shi S., Liu Y., Uyanne J., Shi Y., Shi S., et al. Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. J. Immunol. 2009, 183:7787-7798.
    • (2009) J. Immunol. , vol.183 , pp. 7787-7798
    • Zhang, Q.1    Shi, S.2    Liu, Y.3    Uyanne, J.4    Shi, Y.5    Shi, S.6
  • 73
    • 60449093316 scopus 로고    scopus 로고
    • Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
    • Gonzalez-Rey E., Anderson P., Gonzalez M.A., Rico L., Buscher D., Delgado M. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 2009, 58:929-939.
    • (2009) Gut , vol.58 , pp. 929-939
    • Gonzalez-Rey, E.1    Anderson, P.2    Gonzalez, M.A.3    Rico, L.4    Buscher, D.5    Delgado, M.6
  • 74
    • 80855129560 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis
    • Liang L., Dong C., Chen X., Fang Z., Xu J., Liu M., et al. Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis. Cell Transplant. 2011, 20:1395-1408.
    • (2011) Cell Transplant. , vol.20 , pp. 1395-1408
    • Liang, L.1    Dong, C.2    Chen, X.3    Fang, Z.4    Xu, J.5    Liu, M.6
  • 75
    • 84892978539 scopus 로고    scopus 로고
    • Human umbilical cord-derived mesenchymal stem cells downregulate inflammatory responses by shifting the Treg/Th17 profile in experimental colitis
    • Li L., Liu S., Xu Y., Zhang A., Jiang J., Tan W., et al. Human umbilical cord-derived mesenchymal stem cells downregulate inflammatory responses by shifting the Treg/Th17 profile in experimental colitis. Pharmacology 2013, 92:257-264.
    • (2013) Pharmacology , vol.92 , pp. 257-264
    • Li, L.1    Liu, S.2    Xu, Y.3    Zhang, A.4    Jiang, J.5    Tan, W.6
  • 76
    • 84868566915 scopus 로고    scopus 로고
    • Pre-treatment with IL-1beta enhances the efficacy of MSC transplantation in DSS-induced colitis
    • Fan H., Zhao G., Liu L., Liu F., Gong W., Liu X., et al. Pre-treatment with IL-1beta enhances the efficacy of MSC transplantation in DSS-induced colitis. Cell. Mol. Immunol. 2012, 9:473-481.
    • (2012) Cell. Mol. Immunol. , vol.9 , pp. 473-481
    • Fan, H.1    Zhao, G.2    Liu, L.3    Liu, F.4    Gong, W.5    Liu, X.6
  • 77
    • 84880305357 scopus 로고    scopus 로고
    • Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis
    • Anderson P., Souza-Moreira L., Morell M., Caro M., O'Valle F., Gonzalez-Rey E., et al. Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis. Gut 2013, 62:1131-1141.
    • (2013) Gut , vol.62 , pp. 1131-1141
    • Anderson, P.1    Souza-Moreira, L.2    Morell, M.3    Caro, M.4    O'Valle, F.5    Gonzalez-Rey, E.6
  • 78
    • 84860557456 scopus 로고    scopus 로고
    • New therapies for inflammatory bowel disease: from the bench to the bedside
    • Danese S. New therapies for inflammatory bowel disease: from the bench to the bedside. Gut 2012, 61:918-932.
    • (2012) Gut , vol.61 , pp. 918-932
    • Danese, S.1
  • 79
    • 84904205093 scopus 로고    scopus 로고
    • Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo
    • Chinnadurai R., Garcia M.A., Sakurai Y., Lam W.A., Kirk A.D., Galipeau J., et al. Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo. Stem Cell Rep. 2014, 3:60-72.
    • (2014) Stem Cell Rep. , vol.3 , pp. 60-72
    • Chinnadurai, R.1    Garcia, M.A.2    Sakurai, Y.3    Lam, W.A.4    Kirk, A.D.5    Galipeau, J.6
  • 80
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • Eliopoulos N., Stagg J., Lejeune L., Pommey S., Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood 2005, 106:4057-4065.
    • (2005) Blood , vol.106 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 82
    • 78649895490 scopus 로고    scopus 로고
    • Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study
    • Duijvestein M., Vos A.C., Roelofs H., Wildenberg M.E., Wendrich B.B., Verspaget H.W., et al. Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study. Gut 2010, 59:1662-1669.
    • (2010) Gut , vol.59 , pp. 1662-1669
    • Duijvestein, M.1    Vos, A.C.2    Roelofs, H.3    Wildenberg, M.E.4    Wendrich, B.B.5    Verspaget, H.W.6
  • 84
    • 84928761617 scopus 로고    scopus 로고
    • Safety of mesenchymal stromal cell therapy for inflammatory bowel diseases: results of a 5-year follow-up
    • Kniazev O.V., Parfenov A.I., KO A.G., Ruchkina I.N., Churikova A.A., BykovaF S.V., et al. Safety of mesenchymal stromal cell therapy for inflammatory bowel diseases: results of a 5-year follow-up. Ter. Arkh. 2015, 87:39-44.
    • (2015) Ter. Arkh. , vol.87 , pp. 39-44
    • Kniazev, O.V.1    Parfenov, A.I.2    KO, A.G.3    Ruchkina, I.N.4    Churikova, A.A.5    BykovaF, S.V.6
  • 85
    • 84857047378 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease
    • Liang J., Zhang H., Wang D., Feng X., Wang H., Hua B., et al. Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease. Gut 2012, 61:468-469.
    • (2012) Gut , vol.61 , pp. 468-469
    • Liang, J.1    Zhang, H.2    Wang, D.3    Feng, X.4    Wang, H.5    Hua, B.6
  • 89
    • 10744233679 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for treatment of rectovaginal fistula in perianal Crohn's disease: a new cell-based therapy
    • Garcia-Olmo D., Garcia-Arranz M., Garcia L.G., Cuellar E.S., Blanco I.F., Prianes L.A., et al. Autologous stem cell transplantation for treatment of rectovaginal fistula in perianal Crohn's disease: a new cell-based therapy. Int. J. Colorectal Dis. 2003, 18:451-454.
    • (2003) Int. J. Colorectal Dis. , vol.18 , pp. 451-454
    • Garcia-Olmo, D.1    Garcia-Arranz, M.2    Garcia, L.G.3    Cuellar, E.S.4    Blanco, I.F.5    Prianes, L.A.6
  • 91
    • 64049104052 scopus 로고    scopus 로고
    • Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial
    • Garcia-Olmo D., Herreros D., Pascual I., Pascual J.A., Del-Valle E., Zorrilla J., et al. Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial. Dis. Colon Rectum 2009, 52:79-86.
    • (2009) Dis. Colon Rectum , vol.52 , pp. 79-86
    • Garcia-Olmo, D.1    Herreros, D.2    Pascual, I.3    Pascual, J.A.4    Del-Valle, E.5    Zorrilla, J.6
  • 92
    • 77953206707 scopus 로고    scopus 로고
    • Histopathological analysis of human specimens removed from the injection area of expanded adipose-derived stem cells
    • Garcia-Arranz M., Gomez-Pinedo U., Hardisson D., Herreros D., Guadalajara H., Garcia-Gomez I., et al. Histopathological analysis of human specimens removed from the injection area of expanded adipose-derived stem cells. Histopathology 2010, 56:979-982.
    • (2010) Histopathology , vol.56 , pp. 979-982
    • Garcia-Arranz, M.1    Gomez-Pinedo, U.2    Hardisson, D.3    Herreros, D.4    Guadalajara, H.5    Garcia-Gomez, I.6
  • 93
    • 84863683915 scopus 로고    scopus 로고
    • Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: fistula advanced therapy trial 1) and long-term evaluation
    • Herreros M.D., Garcia-Arranz M., Guadalajara H., De-La-Quintana P., Garcia-Olmo D., Group F.C. Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: fistula advanced therapy trial 1) and long-term evaluation. Dis. Colon Rectum 2012, 55:762-772.
    • (2012) Dis. Colon Rectum , vol.55 , pp. 762-772
    • Herreros, M.D.1    Garcia-Arranz, M.2    Guadalajara, H.3    De-La-Quintana, P.4    Garcia-Olmo, D.5    Group, F.C.6
  • 94
    • 84879459518 scopus 로고    scopus 로고
    • Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial
    • de la Portilla F., Alba F., Garcia-Olmo D., Herrerias J.M., Gonzalez F.X., Galindo A. Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial. Int. J. Colorectal Dis. 2013, 28:313-323.
    • (2013) Int. J. Colorectal Dis. , vol.28 , pp. 313-323
    • de la Portilla, F.1    Alba, F.2    Garcia-Olmo, D.3    Herrerias, J.M.4    Gonzalez, F.X.5    Galindo, A.6
  • 95
    • 84874356143 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells for the treatment of Crohn's fistula: a phase I clinical study
    • Cho Y.B., Lee W.Y., Park K.J., Kim M., Yoo H.W., Yu C.S. Autologous adipose tissue-derived stem cells for the treatment of Crohn's fistula: a phase I clinical study. Cell Transplant. 2013, 22:279-285.
    • (2013) Cell Transplant. , vol.22 , pp. 279-285
    • Cho, Y.B.1    Lee, W.Y.2    Park, K.J.3    Kim, M.4    Yoo, H.W.5    Yu, C.S.6
  • 96
    • 84887040879 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula
    • Lee W.Y., Park K.J., Cho Y.B., Yoon S.N., Song K.H., Kim do S., et al. Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula. Stem Cells 2013, 31:2575-2581.
    • (2013) Stem Cells , vol.31 , pp. 2575-2581
    • Lee, W.Y.1    Park, K.J.2    Cho, Y.B.3    Yoon, S.N.4    Song, K.H.5    Kim do, S.6
  • 98
    • 79955853222 scopus 로고    scopus 로고
    • Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease
    • Ciccocioppo R., Bernardo M.E., Sgarella A., Maccario R., Avanzini M.A., Ubezio C., et al. Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease. Gut 2011, 60:788-798.
    • (2011) Gut , vol.60 , pp. 788-798
    • Ciccocioppo, R.1    Bernardo, M.E.2    Sgarella, A.3    Maccario, R.4    Avanzini, M.A.5    Ubezio, C.6
  • 100
    • 84868091993 scopus 로고    scopus 로고
    • Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials
    • Lalu M.M., McIntyre L., Pugliese C., Fergusson D., Winston B.W., Marshall J.C., et al. Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLOS ONE 2012, 7:e47559.
    • (2012) PLOS ONE , vol.7 , pp. e47559
    • Lalu, M.M.1    McIntyre, L.2    Pugliese, C.3    Fergusson, D.4    Winston, B.W.5    Marshall, J.C.6
  • 102
    • 84855890176 scopus 로고    scopus 로고
    • Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-gamma licensing
    • Francois M., Copland I.B., Yuan S., Romieu-Mourez R., Waller E.K., Galipeau J. Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-gamma licensing. Cytotherapy 2012, 14:147-152.
    • (2012) Cytotherapy , vol.14 , pp. 147-152
    • Francois, M.1    Copland, I.B.2    Yuan, S.3    Romieu-Mourez, R.4    Waller, E.K.5    Galipeau, J.6
  • 103
    • 84906275192 scopus 로고    scopus 로고
    • Do cryopreserved mesenchymal stromal cells display impaired immunomodulatory and therapeutic properties?
    • Moll G., Alm J.J., Davies L.C., von Bahr L., Heldring N., Stenbeck-Funke L., et al. Do cryopreserved mesenchymal stromal cells display impaired immunomodulatory and therapeutic properties?. Stem Cells 2014, 32:2430-2442.
    • (2014) Stem Cells , vol.32 , pp. 2430-2442
    • Moll, G.1    Alm, J.J.2    Davies, L.C.3    von Bahr, L.4    Heldring, N.5    Stenbeck-Funke, L.6
  • 104
    • 70450158753 scopus 로고    scopus 로고
    • Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease
    • Bernardo M.E., Avanzini M.A., Ciccocioppo R., Perotti C., Cometa A.M., Moretta A., et al. Phenotypical/functional characterization of in vitro-expanded mesenchymal stromal cells from patients with Crohn's disease. Cytotherapy 2009, 11:825-836.
    • (2009) Cytotherapy , vol.11 , pp. 825-836
    • Bernardo, M.E.1    Avanzini, M.A.2    Ciccocioppo, R.3    Perotti, C.4    Cometa, A.M.5    Moretta, A.6
  • 105
    • 84872095397 scopus 로고    scopus 로고
    • Inflammatory bowel disease: dysfunction of autophagy?
    • Scharl M., Rogler G. Inflammatory bowel disease: dysfunction of autophagy?. Dig. Dis. 2012, 30(Suppl. 3):12-19.
    • (2012) Dig. Dis. , vol.30 , pp. 12-19
    • Scharl, M.1    Rogler, G.2
  • 106
    • 84888258395 scopus 로고    scopus 로고
    • Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2
    • 1392-1403 e1391-1398.
    • Kim H.S., Shin T.H., Lee B.C., Yu K.R., Seo Y., Lee S., et al. Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2. Gastroenterology 2013, 145. 1392-1403 e1391-1398.
    • (2013) Gastroenterology , vol.145
    • Kim, H.S.1    Shin, T.H.2    Lee, B.C.3    Yu, K.R.4    Seo, Y.5    Lee, S.6
  • 107
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
    • Le Blanc K., Frassoni F., Ball L., Locatelli F., Roelofs H., Lewis I., et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 2008, 371:1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3    Locatelli, F.4    Roelofs, H.5    Lewis, I.6
  • 108
    • 77955361735 scopus 로고    scopus 로고
    • Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus
    • Sun L., Wang D., Liang J., Zhang H., Feng X., Wang H., et al. Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus. Arthritis Rheum. 2010, 62:2467-2475.
    • (2010) Arthritis Rheum. , vol.62 , pp. 2467-2475
    • Sun, L.1    Wang, D.2    Liang, J.3    Zhang, H.4    Feng, X.5    Wang, H.6
  • 109
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert D., Sobinsky J., Douglas G., Kidd M., Moadsiri A., Reina E., et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur. J. Immunol. 2008, 38:1745-1755.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1745-1755
    • Polchert, D.1    Sobinsky, J.2    Douglas, G.3    Kidd, M.4    Moadsiri, A.5    Reina, E.6
  • 110
    • 84927636027 scopus 로고    scopus 로고
    • Failure of interferon-gamma pre-treated mesenchymal stem cell treatment in a patient with Crohn's disease
    • Taddio A., Tommasini A., Valencic E., Biagi E., Decorti G., De Iudicibus S., et al. Failure of interferon-gamma pre-treated mesenchymal stem cell treatment in a patient with Crohn's disease. World J. Gastroenterol. 2015, 21:4379-4384.
    • (2015) World J. Gastroenterol. , vol.21 , pp. 4379-4384
    • Taddio, A.1    Tommasini, A.2    Valencic, E.3    Biagi, E.4    Decorti, G.5    De Iudicibus, S.6
  • 111
    • 80052875315 scopus 로고    scopus 로고
    • Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease
    • Duijvestein M., Molendijk I., Roelofs H., Vos A.C., Verhaar A.P., Reinders M.E., et al. Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease. Cytotherapy 2011, 13:1066-1073.
    • (2011) Cytotherapy , vol.13 , pp. 1066-1073
    • Duijvestein, M.1    Molendijk, I.2    Roelofs, H.3    Vos, A.C.4    Verhaar, A.P.5    Reinders, M.E.6
  • 112
    • 84906911104 scopus 로고    scopus 로고
    • The interaction between mesenchymal stem cells and steroids during inflammation
    • Chen X., Gan Y., Li W., Su J., Zhang Y., Huang Y., et al. The interaction between mesenchymal stem cells and steroids during inflammation. Cell Death Dis. 2014, 5:e1009.
    • (2014) Cell Death Dis. , vol.5 , pp. e1009
    • Chen, X.1    Gan, Y.2    Li, W.3    Su, J.4    Zhang, Y.5    Huang, Y.6
  • 113
    • 0041431109 scopus 로고    scopus 로고
    • Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution
    • Barbash I.M., Chouraqui P., Baron J., Feinberg M.S., Etzion S., Tessone A., et al. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 2003, 108:863-868.
    • (2003) Circulation , vol.108 , pp. 863-868
    • Barbash, I.M.1    Chouraqui, P.2    Baron, J.3    Feinberg, M.S.4    Etzion, S.5    Tessone, A.6
  • 114
    • 84949632189 scopus 로고    scopus 로고
    • Mesenchymal stem cells administered via novel selective mesenteric artery cannulation for the treatment of severe refractory Crohn's disease
    • Dinesen L., Wang A., Vianello F., Tait P., Leen E., Davis J., et al. Mesenchymal stem cells administered via novel selective mesenteric artery cannulation for the treatment of severe refractory Crohn's disease. 4th Conference of ESCO 2009.
    • (2009) 4th Conference of ESCO
    • Dinesen, L.1    Wang, A.2    Vianello, F.3    Tait, P.4    Leen, E.5    Davis, J.6
  • 115
    • 51349121836 scopus 로고    scopus 로고
    • Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice
    • Zhang J., Gong J.F., Zhang W., Zhu W.M., Li J.S. Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice. J. Biomed. Sci. 2008, 15:585-594.
    • (2008) J. Biomed. Sci. , vol.15 , pp. 585-594
    • Zhang, J.1    Gong, J.F.2    Zhang, W.3    Zhu, W.M.4    Li, J.S.5
  • 117
    • 84878757605 scopus 로고    scopus 로고
    • EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool
    • Colletti E., El Shabrawy D., Soland M., Yamagami T., Mokhtari S., Osborne C., et al. EphB2 isolates a human marrow stromal cell subpopulation with enhanced ability to contribute to the resident intestinal cellular pool. FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. 2013, 27:2111-2121.
    • (2013) FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. , vol.27 , pp. 2111-2121
    • Colletti, E.1    El Shabrawy, D.2    Soland, M.3    Yamagami, T.4    Mokhtari, S.5    Osborne, C.6
  • 118
    • 84885111559 scopus 로고    scopus 로고
    • MRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation
    • Levy O., Zhao W., Mortensen L.J., Leblanc S., Tsang K., Fu M., et al. mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation. Blood 2013, 122:e23-e32.
    • (2013) Blood , vol.122 , pp. e23-e32
    • Levy, O.1    Zhao, W.2    Mortensen, L.J.3    Leblanc, S.4    Tsang, K.5    Fu, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.