Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages

Stem Cells

Volumn 31, Issue 9, 2013, Pages 1980-1991

  Melief, Sara M ^a   Schrama, Ellen ^a   Brugman, Martijn H ^a   Tiemessen, Machteld M ^a   Hoogduijn, Martin J ^b   Fibbe, Willem E ^a   Roelofs, Helene ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Bone marrow stromal; Bone marrow stromal cells; CCL18; Mesenchymal stem cells; Monocyte; T cells

Indexed keywords

CD163 ANTIGEN; CD206 ANTIGEN; CHEMOKINE; CYTOKINE; INTERLEUKIN 10; LYMPHOCYTE ANTIGEN; PROTEIN CCL 18; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL INTERACTION; CELL SURVIVAL; CELL VIABILITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MULTIPOTENT STEM CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; STROMA CELL;

BONE MARROW STROMAL; BONE MARROW STROMAL CELLS; CCL18; MESENCHYMAL STEM CELLS; MONOCYTE; T CELLS;

ANTIGENS, CD4; CELL DIFFERENTIATION; CELL SURVIVAL; CHEMOKINES, CC; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INFLAMMATION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MACROPHAGES; MONOCYTES; MULTIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; SOLUBILITY; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84883614526     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1432     Document Type: Article

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