메뉴 건너뛰기




Volumn 5, Issue 1, 2015, Pages 1-10

Targeting activated hepatic stellate cells (aHSCs) for liver fibrosis imaging

Author keywords

Activated hepatic stellate cells (aHSCs); Biomarkers; Ligands; Liver fibrosis; Molecular imaging

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN TYPE 6; DESMIN; FIBRINOGEN; FIBRONECTIN; INDOCYANINE GREEN; MANNOSE 6 PHOSPHATE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SOMATOMEDIN B RECEPTOR; TECHNETIUM 99M; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; VIMENTIN; VITRONECTIN RECEPTOR;

EID: 84949423334     PISSN: None     EISSN: 2191219X     Source Type: Journal    
DOI: 10.1186/s13550-015-0151-x     Document Type: Review
Times cited : (62)

References (117)
  • 1
    • 0036792679 scopus 로고    scopus 로고
    • Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection
    • PID: 12385448
    • Regev A, Berho M, Jeffers LJ, Milikowski C, Molina EG, Pyrsopoulos NT, et al. Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol. 2002;97:2614–8.
    • (2002) Am J Gastroenterol , vol.97 , pp. 2614-2618
    • Regev, A.1    Berho, M.2    Jeffers, L.J.3    Milikowski, C.4    Molina, E.G.5    Pyrsopoulos, N.T.6
  • 3
    • 58849116815 scopus 로고    scopus 로고
    • Elastography for the non-invasive assessment of liver disease: limitations and future developments
    • PID: 19136516
    • Vizzutti F, Arena U, Marra F, Pinzani M. Elastography for the non-invasive assessment of liver disease: limitations and future developments. Gut. 2009;58:157–60.
    • (2009) Gut , vol.58 , pp. 157-160
    • Vizzutti, F.1    Arena, U.2    Marra, F.3    Pinzani, M.4
  • 4
    • 39049101883 scopus 로고    scopus 로고
    • Technology insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography
    • COI: 1:CAS:528:DC%2BD1cXhs1Ojtb8%3D, PID: 18253138
    • Pinzani M, Vizzutti F, Arena U, Marra F. Technology insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography. Nat Clin Pract Gastroenterol Hepatol. 2008;5:95–106.
    • (2008) Nat Clin Pract Gastroenterol Hepatol , vol.5 , pp. 95-106
    • Pinzani, M.1    Vizzutti, F.2    Arena, U.3    Marra, F.4
  • 5
    • 46049100990 scopus 로고    scopus 로고
    • Magnetic resonance elastography for the noninvasive staging of liver fibrosis
    • PID: 18471441
    • Huwart L, Sempoux C, Vicaut E, Salameh N, Annet L, Danse E, et al. Magnetic resonance elastography for the noninvasive staging of liver fibrosis. Gastroenterology. 2008;135:32–40.
    • (2008) Gastroenterology , vol.135 , pp. 32-40
    • Huwart, L.1    Sempoux, C.2    Vicaut, E.3    Salameh, N.4    Annet, L.5    Danse, E.6
  • 6
    • 79952274678 scopus 로고    scopus 로고
    • Assessment of chronic hepatitis and fibrosis: comparison of MR elastography and diffusion-weighted imaging
    • PID: 21343496
    • Wang Y, Ganger DR, Levitsky J, Sternick LA, McCarthy RJ, Chen ZE, et al. Assessment of chronic hepatitis and fibrosis: comparison of MR elastography and diffusion-weighted imaging. AJR Am J Roentgenol. 2011;196:553–61.
    • (2011) AJR Am J Roentgenol , vol.196 , pp. 553-561
    • Wang, Y.1    Ganger, D.R.2    Levitsky, J.3    Sternick, L.A.4    McCarthy, R.J.5    Chen, Z.E.6
  • 7
    • 84863509606 scopus 로고    scopus 로고
    • Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis
    • PID: 22278368
    • Wang QB, Zhu H, Liu HL, Zhang B. Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis. Hepatology. 2012;56:239–47.
    • (2012) Hepatology , vol.56 , pp. 239-247
    • Wang, Q.B.1    Zhu, H.2    Liu, H.L.3    Zhang, B.4
  • 8
    • 24944480766 scopus 로고    scopus 로고
    • Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility
    • PID: 16176786
    • Fahey BJ, Nightingale KR, Nelson RC, Palmeri ML, Trahey GE. Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility. Ultrasound Med Biol. 2005;31:1185–98.
    • (2005) Ultrasound Med Biol , vol.31 , pp. 1185-1198
    • Fahey, B.J.1    Nightingale, K.R.2    Nelson, R.C.3    Palmeri, M.L.4    Trahey, G.E.5
  • 9
    • 70249130127 scopus 로고    scopus 로고
    • Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography
    • PID: 19703889
    • Friedrich-Rust M, Wunder K, Kriener S, Sotoudeh F, Richter S, Bojunga J, et al. Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology. 2009;252:595–604.
    • (2009) Radiology , vol.252 , pp. 595-604
    • Friedrich-Rust, M.1    Wunder, K.2    Kriener, S.3    Sotoudeh, F.4    Richter, S.5    Bojunga, J.6
  • 10
    • 84856591258 scopus 로고    scopus 로고
    • Utility of diffusion-weighted imaging in the evaluation of liver fibrosis
    • PID: 21984447
    • Bakan AA, Inci E, Bakan S, Gokturk S, Cimilli T. Utility of diffusion-weighted imaging in the evaluation of liver fibrosis. Eur Radiol. 2012;22:682–7.
    • (2012) Eur Radiol , vol.22 , pp. 682-687
    • Bakan, A.A.1    Inci, E.2    Bakan, S.3    Gokturk, S.4    Cimilli, T.5
  • 11
    • 58149179092 scopus 로고    scopus 로고
    • Liver cirrhosis: intravoxel incoherent motion MR imaging—pilot study
    • PID: 19011186
    • Luciani A, Vignaud A, Cavet M, Nhieu JT, Mallat A, Ruel L, et al. Liver cirrhosis: intravoxel incoherent motion MR imaging—pilot study. Radiology. 2008;249:891–9.
    • (2008) Radiology , vol.249 , pp. 891-899
    • Luciani, A.1    Vignaud, A.2    Cavet, M.3    Nhieu, J.T.4    Mallat, A.5    Ruel, L.6
  • 12
    • 34748912281 scopus 로고    scopus 로고
    • Diffusion-weighted MRI for quantification of liver fibrosis: preliminary experience
    • PID: 17885048
    • Taouli B, Tolia AJ, Losada M, Babb JS, Chan ES, Bannan MA, et al. Diffusion-weighted MRI for quantification of liver fibrosis: preliminary experience. AJR Am J Roentgenol. 2007;189:799–806.
    • (2007) AJR Am J Roentgenol , vol.189 , pp. 799-806
    • Taouli, B.1    Tolia, A.J.2    Losada, M.3    Babb, J.S.4    Chan, E.S.5    Bannan, M.A.6
  • 13
    • 84899576593 scopus 로고    scopus 로고
    • Evaluation of fibrotic liver disease with whole-liver T1rho MR imaging: a feasibility study at 1.5 T
    • PID: 24475807
    • Allkemper T, Sagmeister F, Cicinnati V, Beckebaum S, Kooijman H, Kanthak C, et al. Evaluation of fibrotic liver disease with whole-liver T1rho MR imaging: a feasibility study at 1.5 T. Radiology. 2014;271:408–15.
    • (2014) Radiology , vol.271 , pp. 408-415
    • Allkemper, T.1    Sagmeister, F.2    Cicinnati, V.3    Beckebaum, S.4    Kooijman, H.5    Kanthak, C.6
  • 14
    • 84864690011 scopus 로고    scopus 로고
    • MR T1rho as an imaging biomarker for monitoring liver injury progression and regression: an experimental study in rats with carbon tetrachloride intoxication
    • PID: 22752522
    • Zhao F, Wang YX, Yuan J, Deng M, Wong HL, Chu ES, et al. MR T1rho as an imaging biomarker for monitoring liver injury progression and regression: an experimental study in rats with carbon tetrachloride intoxication. Eur Radiol. 2012;22:1709–16.
    • (2012) Eur Radiol , vol.22 , pp. 1709-1716
    • Zhao, F.1    Wang, Y.X.2    Yuan, J.3    Deng, M.4    Wong, H.L.5    Chu, E.S.6
  • 15
    • 79956296384 scopus 로고    scopus 로고
    • T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model
    • PID: 21436087
    • Wang YX, Yuan J, Chu ES, Go MY, Huang H, Ahuja AT, et al. T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model. Radiology. 2011;259:712–9.
    • (2011) Radiology , vol.259 , pp. 712-719
    • Wang, Y.X.1    Yuan, J.2    Chu, E.S.3    Go, M.Y.4    Huang, H.5    Ahuja, A.T.6
  • 16
    • 40949099048 scopus 로고    scopus 로고
    • Advanced liver fibrosis: diagnosis with 3D whole-liver perfusion MR imaging—initial experience
    • PID: 18195377
    • Hagiwara M, Rusinek H, Lee VS, Losada M, Bannan MA, Krinsky GA, et al. Advanced liver fibrosis: diagnosis with 3D whole-liver perfusion MR imaging—initial experience. Radiology. 2008;246:926–34.
    • (2008) Radiology , vol.246 , pp. 926-934
    • Hagiwara, M.1    Rusinek, H.2    Lee, V.S.3    Losada, M.4    Bannan, M.A.5    Krinsky, G.A.6
  • 17
    • 84857048025 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging with Gd-EOB-DTPA for the evaluation of liver fibrosis in chronic hepatitis patients
    • PID: 21879400
    • Chen BB, Hsu CY, Yu CW, Wei SY, Kao JH, Lee HS, et al. Dynamic contrast-enhanced magnetic resonance imaging with Gd-EOB-DTPA for the evaluation of liver fibrosis in chronic hepatitis patients. Eur Radiol. 2012;22:171–80.
    • (2012) Eur Radiol , vol.22 , pp. 171-180
    • Chen, B.B.1    Hsu, C.Y.2    Yu, C.W.3    Wei, S.Y.4    Kao, J.H.5    Lee, H.S.6
  • 18
    • 0019439315 scopus 로고
    • The lipocytes in normal human liver. A quantitative study
    • COI: 1:STN:280:DyaL38%2FntlGhsw%3D%3D, PID: 7308589
    • Giampieri MP, Jezequel AM, Orlandi F. The lipocytes in normal human liver. A quantitative study. Digestion. 1981;22:165–9.
    • (1981) Digestion , vol.22 , pp. 165-169
    • Giampieri, M.P.1    Jezequel, A.M.2    Orlandi, F.3
  • 19
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • COI: 1:CAS:528:DC%2BD1cXitVKgsbc%3D, PID: 18195085
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88:125–72.
    • (2008) Physiol Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 20
    • 84893141250 scopus 로고    scopus 로고
    • Hepatic stellate cells and liver fibrosis
    • PID: 24265236
    • Puche JE, Saiman Y, Friedman SL. Hepatic stellate cells and liver fibrosis. Compr Physiol. 2013;3:1473–92.
    • (2013) Compr Physiol , vol.3 , pp. 1473-1492
    • Puche, J.E.1    Saiman, Y.2    Friedman, S.L.3
  • 21
    • 0020581798 scopus 로고
    • Correlation between Ito cells and fibrogenesis in an experimental model of hepatic fibrosis. A sequential stereological study
    • COI: 1:STN:280:DyaL3s3hvVaitA%3D%3D, PID: 6855489
    • Ballardini G, Degli Esposti S, Bianchi FB, de Giorgi LB, Faccani A, Biolchini L, et al. Correlation between Ito cells and fibrogenesis in an experimental model of hepatic fibrosis. A sequential stereological study. Liver. 1983;3:58–63.
    • (1983) Liver , vol.3 , pp. 58-63
    • Ballardini, G.1    Degli Esposti, S.2    Bianchi, F.B.3    de Giorgi, L.B.4    Faccani, A.5    Biolchini, L.6
  • 22
    • 0030296956 scopus 로고    scopus 로고
    • Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis
    • COI: 1:STN:280:DyaK2s%2Fpt12rsQ%3D%3D, PID: 8938545
    • Reeves HL, Burt AD, Wood S, Day CP. Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis. J Hepatol. 1996;25:677–83.
    • (1996) J Hepatol , vol.25 , pp. 677-683
    • Reeves, H.L.1    Burt, A.D.2    Wood, S.3    Day, C.P.4
  • 23
    • 59149102918 scopus 로고    scopus 로고
    • Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection
    • COI: 1:STN:280:DC%2BD1M7htlyktw%3D%3D, PID: 19175868
    • Gonzalez SA, Fiel MI, Sauk J, Canchis PW, Liu RC, Chiriboga L, et al. Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection. J Viral Hepat. 2009;16:141–8.
    • (2009) J Viral Hepat , vol.16 , pp. 141-148
    • Gonzalez, S.A.1    Fiel, M.I.2    Sauk, J.3    Canchis, P.W.4    Liu, R.C.5    Chiriboga, L.6
  • 24
    • 49749145668 scopus 로고    scopus 로고
    • Senescence of activated stellate cells limits liver fibrosis
    • COI: 1:CAS:528:DC%2BD1cXhtVGqtrbI, PID: 18724938
    • Krizhanovsky V, Yon M, Dickins RA, Hearn S, Simon J, Miething C, et al. Senescence of activated stellate cells limits liver fibrosis. Cell. 2008;134:657–67.
    • (2008) Cell , vol.134 , pp. 657-667
    • Krizhanovsky, V.1    Yon, M.2    Dickins, R.A.3    Hearn, S.4    Simon, J.5    Miething, C.6
  • 25
    • 0033858742 scopus 로고    scopus 로고
    • Integrin structure
    • COI: 1:CAS:528:DC%2BD3cXmsVeitb4%3D, PID: 10961914
    • Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28:311–39.
    • (2000) Biochem Soc Trans , vol.28 , pp. 311-339
    • Humphries, M.J.1
  • 27
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: biological implications and therapeutic opportunities
    • COI: 1:CAS:528:DC%2BD1MXhsF2hsLzI, PID: 20029421
    • Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer. 2010;10:9–22.
    • (2010) Nat Rev Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 28
    • 51049108993 scopus 로고    scopus 로고
    • alphavbeta3 integrin and angiogenesis: a moody integrin in a changing environment
    • COI: 1:CAS:528:DC%2BD1cXhtVyks73J, PID: 18638550
    • Hodivala-Dilke K. alphavbeta3 integrin and angiogenesis: a moody integrin in a changing environment. Curr Opin Cell Biol. 2008;20:514–9.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 514-519
    • Hodivala-Dilke, K.1
  • 29
    • 33748616254 scopus 로고    scopus 로고
    • Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism
    • COI: 1:CAS:528:DC%2BD28Xos1Gqt7w%3D, PID: 17017851
    • Cai W, Chen X. Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism. Anticancer Agents Med Chem. 2006;6:407–28.
    • (2006) Anticancer Agents Med Chem , vol.6 , pp. 407-428
    • Cai, W.1    Chen, X.2
  • 30
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • COI: 1:CAS:528:DyaK2cXjt1Sis7w%3D, PID: 7512751
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 1994;264:569–71.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 31
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • COI: 1:CAS:528:DyaL1cXntVKkuw%3D%3D, PID: 2821619
    • Ruoslahti E, Pierschbacher MD. New perspectives in cell adhesion: RGD and integrins. Science. 1987;238:491–7.
    • (1987) Science , vol.238 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.D.2
  • 32
    • 0028899525 scopus 로고
    • Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins
    • COI: 1:CAS:528:DyaK2MXktFWitrs%3D
    • Koivunen E, Wang B, Ruoslahti E. Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins. Biotechnology (N Y). 1995;13:265–70.
    • (1995) Biotechnology (N Y) , vol.13 , pp. 265-270
    • Koivunen, E.1    Wang, B.2    Ruoslahti, E.3
  • 33
    • 4644302286 scopus 로고    scopus 로고
    • Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells
    • PID: 15235124
    • Holig P, Bach M, Volkel T, Nahde T, Hoffmann S, Muller R, et al. Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells. Protein Eng Des Sel. 2004;17:433–41.
    • (2004) Protein Eng Des Sel , vol.17 , pp. 433-441
    • Holig, P.1    Bach, M.2    Volkel, T.3    Nahde, T.4    Hoffmann, S.5    Muller, R.6
  • 34
    • 0025880146 scopus 로고
    • Arg-Gly-Asp constrained within cyclic pentapeptides. Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1
    • COI: 1:CAS:528:DyaK38XisVGh, PID: 1718779
    • Aumailley M, Gurrath M, Muller G, Calvete J, Timpl R, Kessler H. Arg-Gly-Asp constrained within cyclic pentapeptides. Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1. FEBS Lett. 1991;291:50–4.
    • (1991) FEBS Lett , vol.291 , pp. 50-54
    • Aumailley, M.1    Gurrath, M.2    Muller, G.3    Calvete, J.4    Timpl, R.5    Kessler, H.6
  • 35
    • 0029778085 scopus 로고    scopus 로고
    • Structural and functional aspects of RGD-containing cyclic pentapeptides as highly potent and selective integrin αVβ3 antagonists
    • COI: 1:CAS:528:DyaK28XksFKhtrc%3D
    • Haubner R, Gratias R, Diefenbach B, Goodman SL, Jonczyk A, Kessler H. Structural and functional aspects of RGD-containing cyclic pentapeptides as highly potent and selective integrin αVβ3 antagonists. J Am Chem Soc. 1996;118:7461–72.
    • (1996) J Am Chem Soc , vol.118 , pp. 7461-7472
    • Haubner, R.1    Gratias, R.2    Diefenbach, B.3    Goodman, S.L.4    Jonczyk, A.5    Kessler, H.6
  • 36
    • 0033549864 scopus 로고    scopus 로고
    • N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists
    • COI: 1:CAS:528:DyaK1MXksFGhsr0%3D, PID: 10447947
    • Dechantsreiter MA, Planker E, Matha B, Lohof E, Holzemann G, Jonczyk A, et al. N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists. J Med Chem. 1999;42:3033–40.
    • (1999) J Med Chem , vol.42 , pp. 3033-3040
    • Dechantsreiter, M.A.1    Planker, E.2    Matha, B.3    Lohof, E.4    Holzemann, G.5    Jonczyk, A.6
  • 37
    • 27744539110 scopus 로고    scopus 로고
    • Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival
    • COI: 1:CAS:528:DC%2BD2MXht1Wju7%2FL, PID: 16256939
    • Mi J, Zhang X, Giangrande PH, McNamara 2nd JO, Nimjee SM, Sarraf-Yazdi S, et al. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochem Biophys Res Commun. 2005;338:956–63.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 956-963
    • Mi, J.1    Zhang, X.2    Giangrande, P.H.3    McNamara, J.O.4    Nimjee, S.M.5    Sarraf-Yazdi, S.6
  • 39
    • 84888640357 scopus 로고    scopus 로고
    • Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin alphavbeta3 via magnetic resonance imaging
    • PID: 23568770
    • Lim EK, Kim B, Choi Y, Ro Y, Cho EJ, Lee JH, et al. Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin alphavbeta3 via magnetic resonance imaging. J Biomed Mater Res A. 2014;102:49–59.
    • (2014) J Biomed Mater Res A , vol.102 , pp. 49-59
    • Lim, E.K.1    Kim, B.2    Choi, Y.3    Ro, Y.4    Cho, E.J.5    Lee, J.H.6
  • 40
    • 84857033911 scopus 로고    scopus 로고
    • Multimodality imaging of integrin alpha(v)beta(3) expression
    • COI: 1:CAS:528:DC%2BC38Xislaltrc%3D, PID: 21547156
    • Zhang Y, Yang Y, Cai W. Multimodality imaging of integrin alpha(v)beta(3) expression. Theranostics. 2011;1:135–48.
    • (2011) Theranostics , vol.1 , pp. 135-148
    • Zhang, Y.1    Yang, Y.2    Cai, W.3
  • 41
    • 80255141418 scopus 로고    scopus 로고
    • PET imaging of integrin alphaVbeta3 expression
    • COI: 1:CAS:528:DC%2BC38Xislaltrs%3D, PID: 21547152
    • Beer AJ, Kessler H, Wester HJ, Schwaiger M. PET imaging of integrin alphaVbeta3 expression. Theranostics. 2011;1:48–57.
    • (2011) Theranostics , vol.1 , pp. 48-57
    • Beer, A.J.1    Kessler, H.2    Wester, H.J.3    Schwaiger, M.4
  • 43
    • 81555224647 scopus 로고    scopus 로고
    • Integrin targeted delivery of chemotherapeutics
    • COI: 1:CAS:528:DC%2BC38Xislalt7w%3D, PID: 21547159
    • Chen K, Chen X. Integrin targeted delivery of chemotherapeutics. Theranostics. 2011;1:189–200.
    • (2011) Theranostics , vol.1 , pp. 189-200
    • Chen, K.1    Chen, X.2
  • 44
    • 2642537690 scopus 로고    scopus 로고
    • Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells
    • COI: 1:CAS:528:DC%2BD2cXksV2isrY%3D, PID: 15044441
    • Zhou X, Murphy FR, Gehdu N, Zhang J, Iredale JP, Benyon RC. Engagement of alphavbeta3 integrin regulates proliferation and apoptosis of hepatic stellate cells. J Biol Chem. 2004;279:23996–4006.
    • (2004) J Biol Chem , vol.279 , pp. 23996-24006
    • Zhou, X.1    Murphy, F.R.2    Gehdu, N.3    Zhang, J.4    Iredale, J.P.5    Benyon, R.C.6
  • 45
    • 77952287970 scopus 로고    scopus 로고
    • Biochemical characterization of the binding of cyclic RGDyK to hepatic stellate cells
    • COI: 1:CAS:528:DC%2BC3cXlt1Cgtbk%3D, PID: 20303335
    • Huang XW, Wang JY, Li F, Song ZJ, Xie C, Lu WY. Biochemical characterization of the binding of cyclic RGDyK to hepatic stellate cells. Biochem Pharmacol. 2010;80:136–43.
    • (2010) Biochem Pharmacol , vol.80 , pp. 136-143
    • Huang, X.W.1    Wang, J.Y.2    Li, F.3    Song, Z.J.4    Xie, C.5    Lu, W.Y.6
  • 46
    • 79954447126 scopus 로고    scopus 로고
    • MR imaging of activated hepatic stellate cells in liver injured by CCl(4) of rats with integrin-targeted ultrasmall superparamagnetic iron oxide
    • PID: 20972894
    • Wang QB, Han Y, Jiang TT, Chai WM, Chen KM, Liu BY, et al. MR imaging of activated hepatic stellate cells in liver injured by CCl(4) of rats with integrin-targeted ultrasmall superparamagnetic iron oxide. Eur Radiol. 2011;21:1016–25.
    • (2011) Eur Radiol , vol.21 , pp. 1016-1025
    • Wang, Q.B.1    Han, Y.2    Jiang, T.T.3    Chai, W.M.4    Chen, K.M.5    Liu, B.Y.6
  • 47
    • 80052023468 scopus 로고    scopus 로고
    • Molecular imaging of hepatic stellate cell activity by visualization of hepatic integrin alphavbeta3 expression with SPECT in rat
    • COI: 1:CAS:528:DC%2BC3MXhtVOktrvL, PID: 21618580
    • Li F, Song Z, Li Q, Wu J, Wang J, Xie C, et al. Molecular imaging of hepatic stellate cell activity by visualization of hepatic integrin alphavbeta3 expression with SPECT in rat. Hepatology. 2011;54:1020–30.
    • (2011) Hepatology , vol.54 , pp. 1020-1030
    • Li, F.1    Song, Z.2    Li, Q.3    Wu, J.4    Wang, J.5    Xie, C.6
  • 48
    • 34447336118 scopus 로고    scopus 로고
    • (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression
    • COI: 1:CAS:528:DC%2BD2sXhtVertL7F, PID: 17574975
    • Li ZB, Cai W, Cao Q, Chen K, Wu Z, He L, et al. (64)Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor alpha(v)beta(3) integrin expression. J Nucl Med. 2007;48:1162–71.
    • (2007) J Nucl Med , vol.48 , pp. 1162-1171
    • Li, Z.B.1    Cai, W.2    Cao, Q.3    Chen, K.4    Wu, Z.5    He, L.6
  • 49
    • 0032915892 scopus 로고    scopus 로고
    • Integrins and the kidney: biology and pathobiology
    • COI: 1:STN:280:DyaK1M7htlartg%3D%3D, PID: 9914855
    • Hamerski DA, Santoro SA. Integrins and the kidney: biology and pathobiology. Curr Opin Nephrol Hypertens. 1999;8:9–14.
    • (1999) Curr Opin Nephrol Hypertens , vol.8 , pp. 9-14
    • Hamerski, D.A.1    Santoro, S.A.2
  • 50
    • 27944457471 scopus 로고    scopus 로고
    • microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide
    • COI: 1:CAS:528:DC%2BD28XitVGlt7o%3D, PID: 16204722
    • Wu Y, Zhang X, Xiong Z, Cheng Z, Fisher DR, Liu S, et al. microPET imaging of glioma integrin {alpha}v{beta}3 expression using (64)Cu-labeled tetrameric RGD peptide. J Nucl Med. 2005;46:1707–18.
    • (2005) J Nucl Med , vol.46 , pp. 1707-1718
    • Wu, Y.1    Zhang, X.2    Xiong, Z.3    Cheng, Z.4    Fisher, D.R.5    Liu, S.6
  • 51
    • 72449156995 scopus 로고    scopus 로고
    • Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency
    • COI: 1:CAS:528:DC%2BD1MXhtVKmurvJ, PID: 19719118
    • Liu S. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency. Bioconjug Chem. 2009;20:2199–213.
    • (2009) Bioconjug Chem , vol.20 , pp. 2199-2213
    • Liu, S.1
  • 52
    • 84864403424 scopus 로고    scopus 로고
    • The efficient synthesis and biological evaluation of novel bi-functionalized sarcophagine for (64)cu radiopharmaceuticals
    • COI: 1:CAS:528:DC%2BC38XhtFCqsbjN, PID: 22737194
    • Liu S, Li D, Huang CW, Yap LP, Park R, Shan H, et al. The efficient synthesis and biological evaluation of novel bi-functionalized sarcophagine for (64)cu radiopharmaceuticals. Theranostics. 2012;2:589–96.
    • (2012) Theranostics , vol.2 , pp. 589-596
    • Liu, S.1    Li, D.2    Huang, C.W.3    Yap, L.P.4    Park, R.5    Shan, H.6
  • 53
    • 62649159557 scopus 로고    scopus 로고
    • Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers
    • COI: 1:CAS:528:DC%2BD1cXhsVOmt77I, PID: 19067525
    • Wang L, Shi J, Kim YS, Zhai S, Jia B, Zhao H, et al. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. Mol Pharm. 2009;6:231–45.
    • (2009) Mol Pharm , vol.6 , pp. 231-245
    • Wang, L.1    Shi, J.2    Kim, Y.S.3    Zhai, S.4    Jia, B.5    Zhao, H.6
  • 54
    • 80052646479 scopus 로고    scopus 로고
    • Blood clearance kinetics, biodistribution, and radiation dosimetry of a kit-formulated integrin alphavbeta3-selective radiotracer 99mTc-3PRGD 2 in non-human primates
    • PID: 20694579
    • Jia B, Liu Z, Zhu Z, Shi J, Jin X, Zhao H, et al. Blood clearance kinetics, biodistribution, and radiation dosimetry of a kit-formulated integrin alphavbeta3-selective radiotracer 99mTc-3PRGD 2 in non-human primates. Mol Imaging Biol. 2011;13:730–6.
    • (2011) Mol Imaging Biol , vol.13 , pp. 730-736
    • Jia, B.1    Liu, Z.2    Zhu, Z.3    Shi, J.4    Jin, X.5    Zhao, H.6
  • 55
    • 84856209326 scopus 로고    scopus 로고
    • Differential diagnosis of solitary pulmonary nodules using (9)(9)mTc-3P(4)-RGD(2) scintigraphy
    • PID: 21874323
    • Ma Q, Ji B, Jia B, Gao S, Ji T, Wang X, et al. Differential diagnosis of solitary pulmonary nodules using (9)(9)mTc-3P(4)-RGD(2) scintigraphy. Eur J Nucl Med Mol Imaging. 2011;38:2145–52.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 2145-2152
    • Ma, Q.1    Ji, B.2    Jia, B.3    Gao, S.4    Ji, T.5    Wang, X.6
  • 56
    • 84860736140 scopus 로고    scopus 로고
    • 99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study
    • PID: 22499615
    • Zhu Z, Miao W, Li Q, Dai H, Ma Q, Wang F, et al. 99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study. J Nucl Med. 2012;53:716–22.
    • (2012) J Nucl Med , vol.53 , pp. 716-722
    • Zhu, Z.1    Miao, W.2    Li, Q.3    Dai, H.4    Ma, Q.5    Wang, F.6
  • 57
    • 84922927635 scopus 로고    scopus 로고
    • Assessing activation of hepatic stellate cells by (99m)Tc-3PRGD2 scintigraphy targeting integrin alphavbeta3: a feasibility study
    • COI: 1:CAS:528:DC%2BC2MXmt12isA%3D%3D, PID: 25530210
    • Zhang X, Xin J, Shi Y, Xu W, Yu S, Yang Z, et al. Assessing activation of hepatic stellate cells by (99m)Tc-3PRGD2 scintigraphy targeting integrin alphavbeta3: a feasibility study. Nucl Med Biol. 2015;42:250–5.
    • (2015) Nucl Med Biol , vol.42 , pp. 250-255
    • Zhang, X.1    Xin, J.2    Shi, Y.3    Xu, W.4    Yu, S.5    Yang, Z.6
  • 58
    • 67649264901 scopus 로고    scopus 로고
    • Inorganic nanoparticles for MRI contrast agents
    • COI: 1:CAS:528:DC%2BD1MXntVGqu78%3D
    • Na HB, Song IC, Hyeon T. Inorganic nanoparticles for MRI contrast agents. Adv Mater. 2009;21:2133–48.
    • (2009) Adv Mater , vol.21 , pp. 2133-2148
    • Na, H.B.1    Song, I.C.2    Hyeon, T.3
  • 59
    • 0033363494 scopus 로고    scopus 로고
    • Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications
    • COI: 1:CAS:528:DyaK1MXlt12rsrg%3D, PID: 11749483
    • Caravan P, Ellison JJ, McMurry TJ, Lauffer RB. Gadolinium(III) chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev. 1999;99:2293–352.
    • (1999) Chem Rev , vol.99 , pp. 2293-2352
    • Caravan, P.1    Ellison, J.J.2    McMurry, T.J.3    Lauffer, R.B.4
  • 60
    • 84870567279 scopus 로고    scopus 로고
    • A synergistically enhanced T(1)-T(2) dual-modal contrast agent
    • COI: 1:CAS:528:DC%2BC38XhtlGjsrvK, PID: 22972529
    • Zhou Z, Huang D, Bao J, Chen Q, Liu G, Chen Z, et al. A synergistically enhanced T(1)-T(2) dual-modal contrast agent. Adv Mater. 2012;24:6223–8.
    • (2012) Adv Mater , vol.24 , pp. 6223-6228
    • Zhou, Z.1    Huang, D.2    Bao, J.3    Chen, Q.4    Liu, G.5    Chen, Z.6
  • 61
    • 29644442799 scopus 로고    scopus 로고
    • SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells
    • COI: 1:CAS:528:DC%2BD2MXhtlagtLvN, PID: 16365461
    • Huet D, Bagot M, Loyaux D, Capdevielle J, Conraux L, Ferrara P, et al. SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells. J Immunol. 2006;176:652–9.
    • (2006) J Immunol , vol.176 , pp. 652-659
    • Huet, D.1    Bagot, M.2    Loyaux, D.3    Capdevielle, J.4    Conraux, L.5    Ferrara, P.6
  • 62
    • 67650558915 scopus 로고    scopus 로고
    • Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength
    • COI: 1:CAS:528:DC%2BD1MXntFantL0%3D, PID: 19366731
    • Bhattacharya R, Gonzalez AM, Debiase PJ, Trejo HE, Goldman RD, Flitney FW, et al. Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. J Cell Sci. 2009;122:1390–400.
    • (2009) J Cell Sci , vol.122 , pp. 1390-1400
    • Bhattacharya, R.1    Gonzalez, A.M.2    Debiase, P.J.3    Trejo, H.E.4    Goldman, R.D.5    Flitney, F.W.6
  • 63
    • 69549131213 scopus 로고    scopus 로고
    • Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
    • COI: 1:CAS:528:DC%2BD1MXhtFWksLjF, PID: 19666588
    • Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009;106:13820–5.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 13820-13825
    • Creighton, C.J.1    Li, X.2    Landis, M.3    Dixon, J.M.4    Neumeister, V.M.5    Sjolund, A.6
  • 64
    • 77956842633 scopus 로고    scopus 로고
    • Vimentin and desmin possess GlcNAc-binding lectin-like properties on cell surfaces
    • COI: 1:CAS:528:DC%2BC3cXntVGis74%3D, PID: 20332081
    • Ise H, Kobayashi S, Goto M, Sato T, Kawakubo M, Takahashi M, et al. Vimentin and desmin possess GlcNAc-binding lectin-like properties on cell surfaces. Glycobiology. 2010;20:843–64.
    • (2010) Glycobiology , vol.20 , pp. 843-864
    • Ise, H.1    Kobayashi, S.2    Goto, M.3    Sato, T.4    Kawakubo, M.5    Takahashi, M.6
  • 65
    • 0032986367 scopus 로고    scopus 로고
    • Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells
    • COI: 1:CAS:528:DyaK1MXhtFOktrY%3D, PID: 9918930
    • Niki T, Pekny M, Hellemans K, Bleser PD, Berg KV, Vaeyens F, et al. Class VI intermediate filament protein nestin is induced during activation of rat hepatic stellate cells. Hepatology. 1999;29:520–7.
    • (1999) Hepatology , vol.29 , pp. 520-527
    • Niki, T.1    Pekny, M.2    Hellemans, K.3    Bleser, P.D.4    Berg, K.V.5    Vaeyens, F.6
  • 66
    • 84855752968 scopus 로고    scopus 로고
    • Interactions of vimentin- or desmin-expressing liver cells with N-acetylglucosamine-bearing polymers
    • COI: 1:CAS:528:DC%2BC38Xnt1egsg%3D%3D, PID: 22177839
    • Kim SJ, Ise H, Goto M, Akaike T. Interactions of vimentin- or desmin-expressing liver cells with N-acetylglucosamine-bearing polymers. Biomaterials. 2012;33:2154–64.
    • (2012) Biomaterials , vol.33 , pp. 2154-2164
    • Kim, S.J.1    Ise, H.2    Goto, M.3    Akaike, T.4
  • 67
    • 84879107260 scopus 로고    scopus 로고
    • Imaging and therapy of liver fibrosis using bioreducible polyethylenimine/siRNA complexes conjugated with N-acetylglucosamine as a targeting moiety
    • COI: 1:CAS:528:DC%2BC3sXot1Kiurg%3D, PID: 23726228
    • Kim SJ, Ise H, Kim E, Goto M, Akaike T, Chung BH. Imaging and therapy of liver fibrosis using bioreducible polyethylenimine/siRNA complexes conjugated with N-acetylglucosamine as a targeting moiety. Biomaterials. 2013;34:6504–14.
    • (2013) Biomaterials , vol.34 , pp. 6504-6514
    • Kim, S.J.1    Ise, H.2    Kim, E.3    Goto, M.4    Akaike, T.5    Chung, B.H.6
  • 68
    • 79961022478 scopus 로고    scopus 로고
    • Discovery of a linear peptide for improving tumor targeting of gene products and treatment of distal tumors by IL-12 gene therapy
    • COI: 1:CAS:528:DC%2BC3MXivVGgtLo%3D, PID: 21386825
    • Cutrera J, Dibra D, Xia X, Hasan A, Reed S, Li S. Discovery of a linear peptide for improving tumor targeting of gene products and treatment of distal tumors by IL-12 gene therapy. Mol Ther. 2011;19:1468–77.
    • (2011) Mol Ther , vol.19 , pp. 1468-1477
    • Cutrera, J.1    Dibra, D.2    Xia, X.3    Hasan, A.4    Reed, S.5    Li, S.6
  • 69
    • 0024382077 scopus 로고
    • Ligand interactions of the cation-independent mannose 6-phosphate receptor. The stoichiometry of mannose 6-phosphate binding
    • COI: 1:CAS:528:DyaL1MXkvFant7s%3D, PID: 2542254
    • Tong PY, Gregory W, Kornfeld S. Ligand interactions of the cation-independent mannose 6-phosphate receptor. The stoichiometry of mannose 6-phosphate binding. J Biol Chem. 1989;264:7962–9.
    • (1989) J Biol Chem , vol.264 , pp. 7962-7969
    • Tong, P.Y.1    Gregory, W.2    Kornfeld, S.3
  • 70
    • 0023834404 scopus 로고
    • The cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II
    • COI: 1:CAS:528:DyaL1cXht1Ghtr0%3D, PID: 2963812
    • Tong PY, Tollefsen SE, Kornfeld S. The cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II. J Biol Chem. 1988;263:2585–8.
    • (1988) J Biol Chem , vol.263 , pp. 2585-2588
    • Tong, P.Y.1    Tollefsen, S.E.2    Kornfeld, S.3
  • 71
    • 0023846016 scopus 로고
    • A single receptor binds both insulin-like growth factor II and mannose-6-phosphate
    • COI: 1:CAS:528:DyaL1cXhs1emsrg%3D, PID: 2964083
    • MacDonald RG, Pfeffer SR, Coussens L, Tepper MA, Brocklebank CM, Mole JE, et al. A single receptor binds both insulin-like growth factor II and mannose-6-phosphate. Science. 1988;239:1134–7.
    • (1988) Science , vol.239 , pp. 1134-1137
    • MacDonald, R.G.1    Pfeffer, S.R.2    Coussens, L.3    Tepper, M.A.4    Brocklebank, C.M.5    Mole, J.E.6
  • 72
    • 0029048875 scopus 로고
    • Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells
    • PID: 7737649
    • de Bleser PJ, Jannes P, van Buul-Offers SC, Hoogerbrugge CM, van Schravendijk CF, Niki T, et al. Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells. Hepatology. 1995;21:1429–37.
    • (1995) Hepatology , vol.21 , pp. 1429-1437
    • de Bleser, P.J.1    Jannes, P.2    van Buul-Offers, S.C.3    Hoogerbrugge, C.M.4    van Schravendijk, C.F.5    Niki, T.6
  • 73
    • 33746919645 scopus 로고    scopus 로고
    • Mannose-6-phosphate/insulin-like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells
    • COI: 1:CAS:528:DC%2BD28XnvVymsb0%3D, PID: 16850269
    • Greupink R, Bakker HI, van Goor H, de Borst MH, Beljaars L, Poelstra K. Mannose-6-phosphate/insulin-like growth factor-II receptors may represent a target for the selective delivery of mycophenolic acid to fibrogenic cells. Pharm Res. 2006;23:1827–34.
    • (2006) Pharm Res , vol.23 , pp. 1827-1834
    • Greupink, R.1    Bakker, H.I.2    van Goor, H.3    de Borst, M.H.4    Beljaars, L.5    Poelstra, K.6
  • 74
    • 0026059613 scopus 로고
    • Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor
    • COI: 1:CAS:528:DyaK3MXpsFOmsw%3D%3D, PID: 1846448
    • Dennis PA, Rifkin DB. Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci U S A. 1991;88:580–4.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 580-584
    • Dennis, P.A.1    Rifkin, D.B.2
  • 75
    • 0032899156 scopus 로고    scopus 로고
    • Albumin modified with mannose 6-phosphate: a potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells
    • COI: 1:CAS:528:DyaK1MXjt1Wnu7k%3D, PID: 10216133
    • Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, et al. Albumin modified with mannose 6-phosphate: a potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells. Hepatology. 1999;29:1486–93.
    • (1999) Hepatology , vol.29 , pp. 1486-1493
    • Beljaars, L.1    Molema, G.2    Weert, B.3    Bonnema, H.4    Olinga, P.5    Groothuis, G.M.6
  • 76
    • 33645868663 scopus 로고    scopus 로고
    • The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo
    • COI: 1:CAS:528:DC%2BD28XktFamtLo%3D, PID: 16439617
    • Greupink R, Bakker HI, Bouma W, Reker-Smit C, Meijer DK, Beljaars L, et al. The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo. J Pharmacol Exp Ther. 2006;317:514–21.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 514-521
    • Greupink, R.1    Bakker, H.I.2    Bouma, W.3    Reker-Smit, C.4    Meijer, D.K.5    Beljaars, L.6
  • 77
    • 34248513301 scopus 로고    scopus 로고
    • Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells
    • COI: 1:CAS:528:DC%2BD2sXmsFeru78%3D, PID: 17369283
    • Gonzalo T, Beljaars L, van de Bovenkamp M, Temming K, van Loenen AM, Reker-Smit C, et al. Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells. J Pharmacol Exp Ther. 2007;321:856–65.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 856-865
    • Gonzalo, T.1    Beljaars, L.2    van de Bovenkamp, M.3    Temming, K.4    van Loenen, A.M.5    Reker-Smit, C.6
  • 78
    • 40849106637 scopus 로고    scopus 로고
    • Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers
    • COI: 1:CAS:528:DC%2BD1cXivVajsrs%3D, PID: 18077624
    • Hagens WI, Beljaars L, Mann DA, Wright MC, Julien B, Lotersztajn S, et al. Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers. J Pharmacol Exp Ther. 2008;324:902–10.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 902-910
    • Hagens, W.I.1    Beljaars, L.2    Mann, D.A.3    Wright, M.C.4    Julien, B.5    Lotersztajn, S.6
  • 79
    • 77950608186 scopus 로고    scopus 로고
    • Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats
    • COI: 1:CAS:528:DC%2BC3cXks1SqsLw%3D, PID: 20044807
    • Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, et al. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology. 2010;51:942–52.
    • (2010) Hepatology , vol.51 , pp. 942-952
    • Moreno, M.1    Gonzalo, T.2    Kok, R.J.3    Sancho-Bru, P.4    van Beuge, M.5    Swart, J.6
  • 81
    • 12344286971 scopus 로고    scopus 로고
    • Mono- and bivalent ligands bearing mannose 6-phosphate (M6P) surrogates: targeting the M6P/insulin-like growth factor II receptor
    • COI: 1:CAS:528:DC%2BD2cXhtVCru7jO, PID: 15606100
    • Berkowitz DB, Maiti G, Charette BD, Dreis CD, MacDonald RG. Mono- and bivalent ligands bearing mannose 6-phosphate (M6P) surrogates: targeting the M6P/insulin-like growth factor II receptor. Org Lett. 2004;6:4921–4.
    • (2004) Org Lett , vol.6 , pp. 4921-4924
    • Berkowitz, D.B.1    Maiti, G.2    Charette, B.D.3    Dreis, C.D.4    MacDonald, R.G.5
  • 82
    • 33645887257 scopus 로고    scopus 로고
    • Synthesis and receptor binding affinity of carboxylate analogues of the mannose 6-phosphate recognition marker
    • COI: 1:CAS:528:DC%2BD28XjtFGju7c%3D, PID: 16455258
    • Jeanjean A, Garcia M, Leydet A, Montero JL, Morere A. Synthesis and receptor binding affinity of carboxylate analogues of the mannose 6-phosphate recognition marker. Bioorg Med Chem. 2006;14:3575–82.
    • (2006) Bioorg Med Chem , vol.14 , pp. 3575-3582
    • Jeanjean, A.1    Garcia, M.2    Leydet, A.3    Montero, J.L.4    Morere, A.5
  • 83
    • 36849049303 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptor targeting and its applications in human diseases
    • COI: 1:CAS:528:DC%2BD1cXhtlSrs74%3D, PID: 18220730
    • Gary-Bobo M, Nirde P, Jeanjean A, Morere A, Garcia M. Mannose 6-phosphate receptor targeting and its applications in human diseases. Curr Med Chem. 2007;14:2945–53.
    • (2007) Curr Med Chem , vol.14 , pp. 2945-2953
    • Gary-Bobo, M.1    Nirde, P.2    Jeanjean, A.3    Morere, A.4    Garcia, M.5
  • 84
    • 50649101286 scopus 로고    scopus 로고
    • Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI)
    • COI: 1:CAS:528:DC%2BD1cXotlOitbc%3D, PID: 18400749
    • Fitzgerald J, Rich C, Zhou FH, Hansen U. Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI). J Biol Chem. 2008;283:20170–80.
    • (2008) J Biol Chem , vol.283 , pp. 20170-20180
    • Fitzgerald, J.1    Rich, C.2    Zhou, F.H.3    Hansen, U.4
  • 85
    • 0022539753 scopus 로고
    • Molecular assembly, secretion, and matrix deposition of type VI collagen
    • COI: 1:CAS:528:DyaL28XhsVKhtLY%3D, PID: 3456350
    • Engvall E, Hessle H, Klier G. Molecular assembly, secretion, and matrix deposition of type VI collagen. J Cell Biol. 1986;102:703–10.
    • (1986) J Cell Biol , vol.102 , pp. 703-710
    • Engvall, E.1    Hessle, H.2    Klier, G.3
  • 86
    • 84962957729 scopus 로고    scopus 로고
    • Type VI collagen: its biology and value as a biomarker of hepatic fibrosis
    • Mak KM, Sehgal P, Harris CK. Type VI collagen: its biology and value as a biomarker of hepatic fibrosis. Austin Biomark Diagn. 2014;1:1–9.
    • (2014) Austin Biomark Diagn , vol.1 , pp. 1-9
    • Mak, K.M.1    Sehgal, P.2    Harris, C.K.3
  • 87
    • 0026574956 scopus 로고
    • Distribution and cellular origin of collagen VI during development and in cirrhosis
    • COI: 1:STN:280:DyaK387msFSgsA%3D%3D, PID: 1537534
    • Loreal O, Clement B, Schuppan D, Rescan PY, Rissel M, Guillouzo A. Distribution and cellular origin of collagen VI during development and in cirrhosis. Gastroenterology. 1992;102:980–7.
    • (1992) Gastroenterology , vol.102 , pp. 980-987
    • Loreal, O.1    Clement, B.2    Schuppan, D.3    Rescan, P.Y.4    Rissel, M.5    Guillouzo, A.6
  • 88
    • 0022227205 scopus 로고
    • Radioimmunoassay for human type VI collagen and its application to tissue and body fluids
    • COI: 1:CAS:528:DyaL2MXltF2jtbg%3D, PID: 4073480
    • Schuppan D, Ruhlmann T, Hahn EG. Radioimmunoassay for human type VI collagen and its application to tissue and body fluids. Anal Biochem. 1985;149:238–47.
    • (1985) Anal Biochem , vol.149 , pp. 238-247
    • Schuppan, D.1    Ruhlmann, T.2    Hahn, E.G.3
  • 89
    • 0028938520 scopus 로고
    • Type VI collagen gene expression in experimental liver fibrosis: quantitation and spatial distribution of mRNAs, and immunodetection of the protein
    • COI: 1:STN:280:DyaK2MzhtFKlsA%3D%3D, PID: 7791542
    • Takahara T, Sollberg S, Muona P, Uitto J. Type VI collagen gene expression in experimental liver fibrosis: quantitation and spatial distribution of mRNAs, and immunodetection of the protein. Liver. 1995;15:78–86.
    • (1995) Liver , vol.15 , pp. 78-86
    • Takahara, T.1    Sollberg, S.2    Muona, P.3    Uitto, J.4
  • 90
    • 0025985998 scopus 로고
    • Cell adhesion to type-VI collagen
    • COI: 1:CAS:528:DyaK3MXlsFGmu74%3D, PID: 1794570
    • Aumailley M, Specks U, Timpl R. Cell adhesion to type-VI collagen. Biochem Soc Trans. 1991;19:843–7.
    • (1991) Biochem Soc Trans , vol.19 , pp. 843-847
    • Aumailley, M.1    Specks, U.2    Timpl, R.3
  • 91
    • 0027189862 scopus 로고
    • Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI
    • COI: 1:CAS:528:DyaK3sXkvFait7k%3D, PID: 8387021
    • Pfaff M, Aumailley M, Specks U, Knolle J, Zerwes HG, Timpl R. Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI. Exp Cell Res. 1993;206:167–76.
    • (1993) Exp Cell Res , vol.206 , pp. 167-176
    • Pfaff, M.1    Aumailley, M.2    Specks, U.3    Knolle, J.4    Zerwes, H.G.5    Timpl, R.6
  • 92
    • 0023555151 scopus 로고
    • Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits
    • COI: 1:CAS:528:DyaL1cXjvF2j, PID: 2822727
    • Wayner EA, Carter WG. Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits. J Cell Biol. 1987;105:1873–84.
    • (1987) J Cell Biol , vol.105 , pp. 1873-1884
    • Wayner, E.A.1    Carter, W.G.2
  • 93
    • 0029921945 scopus 로고    scopus 로고
    • Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules
    • COI: 1:CAS:528:DyaK28XmsVCgs74%3D, PID: 8824254
    • Burg MA, Tillet E, Timpl R, Stallcup WB. Binding of the NG2 proteoglycan to type VI collagen and other extracellular matrix molecules. J Biol Chem. 1996;271:26110–6.
    • (1996) J Biol Chem , vol.271 , pp. 26110-26116
    • Burg, M.A.1    Tillet, E.2    Timpl, R.3    Stallcup, W.B.4
  • 94
    • 0027131865 scopus 로고
    • Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface
    • COI: 1:CAS:528:DyaK2cXitFektLk%3D, PID: 8305732
    • Nishiyama A, Stallcup WB. Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface. Mol Biol Cell. 1993;4:1097–108.
    • (1993) Mol Biol Cell , vol.4 , pp. 1097-1108
    • Nishiyama, A.1    Stallcup, W.B.2
  • 95
    • 0025663548 scopus 로고
    • Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen
    • COI: 1:CAS:528:DyaK3cXmt1yhuro%3D, PID: 2269670
    • Stallcup WB, Dahlin K, Healy P. Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen. J Cell Biol. 1990;111:3177–88.
    • (1990) J Cell Biol , vol.111 , pp. 3177-3188
    • Stallcup, W.B.1    Dahlin, K.2    Healy, P.3
  • 96
    • 0029053333 scopus 로고
    • Attachment of articular cartilage chondrocytes to the tissue form of type VI collagen
    • PID: 7599172
    • Marcelino J, McDevitt CA. Attachment of articular cartilage chondrocytes to the tissue form of type VI collagen. Biochim Biophys Acta. 1995;1249:180–8.
    • (1995) Biochim Biophys Acta , vol.1249 , pp. 180-188
    • Marcelino, J.1    McDevitt, C.A.2
  • 97
    • 0034724911 scopus 로고    scopus 로고
    • Successful targeting to rat hepatic stellate cells using albumin modified with cyclic peptides that recognize the collagen type VI receptor
    • COI: 1:CAS:528:DC%2BD3cXjtVartbs%3D, PID: 10777570
    • Beljaars L, Molema G, Schuppan D, Geerts A, De Bleser PJ, Weert B, et al. Successful targeting to rat hepatic stellate cells using albumin modified with cyclic peptides that recognize the collagen type VI receptor. J Biol Chem. 2000;275:12743–51.
    • (2000) J Biol Chem , vol.275 , pp. 12743-12751
    • Beljaars, L.1    Molema, G.2    Schuppan, D.3    Geerts, A.4    De Bleser, P.J.5    Weert, B.6
  • 98
    • 34547137386 scopus 로고    scopus 로고
    • Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats
    • COI: 1:CAS:528:DC%2BD2sXoslSjtLo%3D, PID: 17510318
    • Du SL, Pan H, Lu WY, Wang J, Wu J, Wang JY. Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats. J Pharmacol Exp Ther. 2007;322:560–8.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 560-568
    • Du, S.L.1    Pan, H.2    Lu, W.Y.3    Wang, J.4    Wu, J.5    Wang, J.Y.6
  • 99
    • 52049106824 scopus 로고    scopus 로고
    • Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis
    • COI: 1:CAS:528:DC%2BD1cXhtFensbzN, PID: 18692530
    • Li F, Sun JY, Wang JY, Du SL, Lu WY, Liu M, et al. Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis. J Control Release. 2008;131:77–82.
    • (2008) J Control Release , vol.131 , pp. 77-82
    • Li, F.1    Sun, J.Y.2    Wang, J.Y.3    Du, S.L.4    Lu, W.Y.5    Liu, M.6
  • 100
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • COI: 1:CAS:528:DC%2BD2cXltVKhtL8%3D, PID: 15207816
    • Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 2004;15:255–73.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 101
    • 2942676788 scopus 로고    scopus 로고
    • The PDGF family: four gene products form five dimeric isoforms
    • COI: 1:CAS:528:DC%2BD2cXltVKht7g%3D, PID: 15207811
    • Fredriksson L, Li H, Eriksson U. The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev. 2004;15:197–204.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 197-204
    • Fredriksson, L.1    Li, H.2    Eriksson, U.3
  • 102
    • 0028170153 scopus 로고
    • Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture
    • COI: 1:CAS:528:DyaK2cXmt1aqtbw%3D, PID: 7929832
    • Wong L, Yamasaki G, Johnson RJ, Friedman SL. Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture. J Clin Invest. 1994;94:1563–9.
    • (1994) J Clin Invest , vol.94 , pp. 1563-1569
    • Wong, L.1    Yamasaki, G.2    Johnson, R.J.3    Friedman, S.L.4
  • 103
    • 0030091214 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis
    • COI: 1:CAS:528:DyaK28Xit1yitb8%3D, PID: 8774134
    • Pinzani M, Milani S, Herbst H, DeFranco R, Grappone C, Gentilini A, et al. Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol. 1996;148:785–800.
    • (1996) Am J Pathol , vol.148 , pp. 785-800
    • Pinzani, M.1    Milani, S.2    Herbst, H.3    DeFranco, R.4    Grappone, C.5    Gentilini, A.6
  • 104
    • 0025987534 scopus 로고
    • Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation
    • COI: 1:CAS:528:DyaK3sXjtlCltg%3D%3D, PID: 1661670
    • Clements JM, Bawden LJ, Bloxidge RE, Catlin G, Cook AL, Craig S, et al. Two PDGF-B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation. EMBO J. 1991;10:4113–20.
    • (1991) EMBO J , vol.10 , pp. 4113-4120
    • Clements, J.M.1    Bawden, L.J.2    Bloxidge, R.E.3    Catlin, G.4    Cook, A.L.5    Craig, S.6
  • 105
    • 0141740706 scopus 로고    scopus 로고
    • The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue
    • COI: 1:CAS:528:DC%2BD3sXnsVamsLk%3D, PID: 14505810
    • Beljaars L, Weert B, Geerts A, Meijer DK, Poelstra K. The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue. Biochem Pharmacol. 2003;66:1307–17.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1307-1317
    • Beljaars, L.1    Weert, B.2    Geerts, A.3    Meijer, D.K.4    Poelstra, K.5
  • 107
    • 84862777181 scopus 로고    scopus 로고
    • Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor-beta on hepatic fibrosis in rats
    • COI: 1:CAS:528:DC%2BC38XntVWisbc%3D, PID: 22226772
    • Li F, Li QH, Wang JY, Zhan CY, Xie C, Lu WY. Effects of interferon-gamma liposomes targeted to platelet-derived growth factor receptor-beta on hepatic fibrosis in rats. J Control Release. 2012;159:261–70.
    • (2012) J Control Release , vol.159 , pp. 261-270
    • Li, F.1    Li, Q.H.2    Wang, J.Y.3    Zhan, C.Y.4    Xie, C.5    Lu, W.Y.6
  • 108
    • 84862670553 scopus 로고    scopus 로고
    • The improving effects on hepatic fibrosis of interferon-gamma liposomes targeted to hepatic stellate cells
    • PID: 22700686
    • Li Q, Yan Z, Li F, Lu W, Wang J, Guo C. The improving effects on hepatic fibrosis of interferon-gamma liposomes targeted to hepatic stellate cells. Nanotechnology. 2012;23:265101.
    • (2012) Nanotechnology , vol.23 , pp. 265101
    • Li, Q.1    Yan, Z.2    Li, F.3    Lu, W.4    Wang, J.5    Guo, C.6
  • 109
    • 0026670167 scopus 로고
    • Identification of a peptide antagonist for platelet-derived growth factor
    • COI: 1:STN:280:DyaK38zlsFKgsA%3D%3D, PID: 1322909
    • Engstrom U, Engstrom A, Ernlund A, Westermark B, Heldin CH. Identification of a peptide antagonist for platelet-derived growth factor. J Biol Chem. 1992;267:16581–7.
    • (1992) J Biol Chem , vol.267 , pp. 16581-16587
    • Engstrom, U.1    Engstrom, A.2    Ernlund, A.3    Westermark, B.4    Heldin, C.H.5
  • 110
    • 0030805072 scopus 로고    scopus 로고
    • Identification of a cyclic peptide inhibitor of platelet-derived growth factor-BB receptor-binding and mitogen-induced DNA synthesis in human fibroblasts
    • COI: 1:CAS:528:DyaK2sXlt1GlsLc%3D, PID: 9287119
    • Brennand DM, Dennehy U, Ellis V, Scully MF, Tripathi P, Kakkar VV, et al. Identification of a cyclic peptide inhibitor of platelet-derived growth factor-BB receptor-binding and mitogen-induced DNA synthesis in human fibroblasts. FEBS Lett. 1997;413:70–4.
    • (1997) FEBS Lett , vol.413 , pp. 70-74
    • Brennand, D.M.1    Dennehy, U.2    Ellis, V.3    Scully, M.F.4    Tripathi, P.5    Kakkar, V.V.6
  • 111
    • 0031435566 scopus 로고    scopus 로고
    • A cyclic peptide analogue of loop III of PDGF-BB causes apoptosis in human fibroblasts
    • COI: 1:CAS:528:DyaK2sXnvFGks7g%3D, PID: 9428627
    • Brennand DM, Scully MF, Kakkar VV, Patel G. A cyclic peptide analogue of loop III of PDGF-BB causes apoptosis in human fibroblasts. FEBS Lett. 1997;419:166–70.
    • (1997) FEBS Lett , vol.419 , pp. 166-170
    • Brennand, D.M.1    Scully, M.F.2    Kakkar, V.V.3    Patel, G.4
  • 112
    • 0029949727 scopus 로고    scopus 로고
    • Identification of three amino acid residues in the B-chain of platelet-derived growth factor with different importance for binding to PDGF alpha- and beta-receptors
    • COI: 1:CAS:528:DyaK28XivFOhsrg%3D, PID: 8647246
    • Kreysing J, Ostman A, van de Poll M, Backstrom G, Heldin CH. Identification of three amino acid residues in the B-chain of platelet-derived growth factor with different importance for binding to PDGF alpha- and beta-receptors. FEBS Lett. 1996;385:181–4.
    • (1996) FEBS Lett , vol.385 , pp. 181-184
    • Kreysing, J.1    Ostman, A.2    van de Poll, M.3    Backstrom, G.4    Heldin, C.H.5
  • 113
    • 84897573237 scopus 로고    scopus 로고
    • Inhibition of receptor signaling and of glioblastoma-derived tumor growth by a novel PDGFRbeta aptamer
    • COI: 1:CAS:528:DC%2BC2cXhs12ht74%3D, PID: 24566984
    • Camorani S, Esposito CL, Rienzo A, Catuogno S, Iaboni M, Condorelli G, et al. Inhibition of receptor signaling and of glioblastoma-derived tumor growth by a novel PDGFRbeta aptamer. Mol Ther. 2014;22:828–41.
    • (2014) Mol Ther , vol.22 , pp. 828-841
    • Camorani, S.1    Esposito, C.L.2    Rienzo, A.3    Catuogno, S.4    Iaboni, M.5    Condorelli, G.6
  • 114
    • 0036717382 scopus 로고    scopus 로고
    • Molecular imaging of cancer with positron emission tomography
    • COI: 1:CAS:528:DC%2BD38Xmslanu7c%3D, PID: 12209157
    • Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer. 2002;2:683–93.
    • (2002) Nat Rev Cancer , vol.2 , pp. 683-693
    • Gambhir, S.S.1
  • 115
    • 84944740458 scopus 로고    scopus 로고
    • Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery
    • PID: 26441654
    • Paefgen V, Doleschel D, Kiessling F. Evolution of contrast agents for ultrasound imaging and ultrasound-mediated drug delivery. Front Pharmacol. 2015;6:197.
    • (2015) Front Pharmacol , vol.6 , pp. 197
    • Paefgen, V.1    Doleschel, D.2    Kiessling, F.3
  • 116
    • 79960727727 scopus 로고    scopus 로고
    • Hepatic stellate cells: partners in crime for liver metastases?
    • COI: 1:CAS:528:DC%2BC3MXpt1yju70%3D, PID: 21520207
    • Kang N, Gores GJ, Shah VH. Hepatic stellate cells: partners in crime for liver metastases? Hepatology. 2011;54:707–13.
    • (2011) Hepatology , vol.54 , pp. 707-713
    • Kang, N.1    Gores, G.J.2    Shah, V.H.3
  • 117
    • 84901203792 scopus 로고    scopus 로고
    • Stellate cells and the development of liver cancer: therapeutic potential of targeting the stroma
    • COI: 1:CAS:528:DC%2BC2cXkslegtLo%3D, PID: 24530649
    • Coulouarn C, Clement B. Stellate cells and the development of liver cancer: therapeutic potential of targeting the stroma. J Hepatol. 2014;60:1306–9.
    • (2014) J Hepatol , vol.60 , pp. 1306-1309
    • Coulouarn, C.1    Clement, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.