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Volumn 11, Issue 11, 2015, Pages

Automated and Accurate Estimation of Gene Family Abundance from Shotgun Metagenomes

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; DISEASES; DNA SEQUENCES; GENE ENCODING;

EID: 84949219026     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004573     Document Type: Article
Times cited : (48)

References (83)
  • 1
    • 34547433545 scopus 로고    scopus 로고
    • Global patterns in bacterial diversity
    • Lozupone CA, Knight R, Global patterns in bacterial diversity. Proc Natl Acad Sci U S A [Internet]. 2007 Jul 3 [cited 2014 Dec 17];104(27):11436–40. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2040916&tool=pmcentrez&rendertype=abstract 17592124
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.27 , pp. 11436-11440
    • Lozupone, C.A.1    Knight, R.2
  • 2
    • 84865345637 scopus 로고    scopus 로고
    • Stochastic and deterministic assembly processes in subsurface microbial communities
    • Stegen JC, Lin X, Konopka AE, Fredrickson JK, Stochastic and deterministic assembly processes in subsurface microbial communities. ISME J [Internet]. 2012 Sep [cited 2015 Feb 18];6(9):1653–64. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3498916&tool=pmcentrez&rendertype=abstract doi: 10.1038/ismej.2012.22 22456445
    • (2012) ISME J , vol.6 , Issue.9 , pp. 1653-1664
    • Stegen, J.C.1    Lin, X.2    Konopka, A.E.3    Fredrickson, J.K.4
  • 3
    • 84355163066 scopus 로고    scopus 로고
    • Illumina-based analysis of microbial community diversity
    • Degnan PH, Ochman H, Illumina-based analysis of microbial community diversity. ISME J [Internet]. International Society for Microbial Ecology; 2012 Jan [cited 2014 Mar 19];6(1):183–94. http://dx.doi.org/10.1038/ismej.2011.74 doi: 10.1038/ismej.2011.74 21677692
    • (2012) ISME J , vol.6 , Issue.1 , pp. 183-194
    • Degnan, P.H.1    Ochman, H.2
  • 4
    • 84880917665 scopus 로고    scopus 로고
    • Temporal variability in soil microbial communities across land-use types
    • Lauber CL, Ramirez KS, Aanderud Z, Lennon J, Fierer N, Temporal variability in soil microbial communities across land-use types. ISME J [Internet]. 2013 Aug [cited 2014 Nov 23];7(8):1641–50. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3721119&tool=pmcentrez&rendertype=abstract doi: 10.1038/ismej.2013.50 23552625
    • (2013) ISME J , vol.7 , Issue.8 , pp. 1641-1650
    • Lauber, C.L.1    Ramirez, K.S.2    Aanderud, Z.3    Lennon, J.4    Fierer, N.5
  • 5
    • 84979608055 scopus 로고    scopus 로고
    • An introduction to the analysis of shotgun metagenomic data
    • Sharpton TJ, An introduction to the analysis of shotgun metagenomic data. Front Plant Sci [Internet]. 2014 Jan [cited 2014 Jul 9];5:209. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4059276&tool=pmcentrez&rendertype=abstract doi: 10.3389/fpls.2014.00209 24982662
    • (2014) Front Plant Sci , vol.5 , pp. 209
    • Sharpton, T.J.1
  • 6
    • 33847702910 scopus 로고    scopus 로고
    • MEGAN analysis of metagenomic data
    • Huson DH, Auch AF, Qi J, Schuster SC, MEGAN analysis of metagenomic data. Genome Res [Internet]. 2007 Mar [cited 2014 Jul 9];17(3):377–86. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1800929&tool=pmcentrez&rendertype=abstract 17255551
    • (2007) Genome Res , vol.17 , Issue.3 , pp. 377-386
    • Huson, D.H.1    Auch, A.F.2    Qi, J.3    Schuster, S.C.4
  • 7
    • 84864037467 scopus 로고    scopus 로고
    • Metabolic reconstruction for metagenomic data and its application to the human microbiome
    • Abubucker S, Segata N, Goll J, Schubert AM, Izard J, Cantarel BL, et al. Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput Biol [Internet]. 2012 Jan [cited 2014 Jan 23];8(6):e1002358. from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3374609&tool=pmcentrez&rendertype=abstract doi: 10.1371/journal.pcbi.1002358 22719234
    • (2012) PLoS Comput Biol , vol.8 , Issue.6 , pp. e1002358
    • Abubucker, S.1    Segata, N.2    Goll, J.3    Schubert, A.M.4    Izard, J.5    Cantarel, B.L.6
  • 8
    • 71749111168 scopus 로고    scopus 로고
    • Analysis and comparison of very large metagenomes with fast clustering and functional annotation
    • Li W, Analysis and comparison of very large metagenomes with fast clustering and functional annotation. BMC Bioinformatics [Internet]. 2009 Jan [cited 2014 Jan 25];10:359. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2774329&tool=pmcentrez&rendertype=abstract doi: 10.1186/1471-2105-10-359 19863816
    • (2009) BMC Bioinformatics , vol.10 , pp. 359
    • Li, W.1
  • 9
    • 78449297680 scopus 로고    scopus 로고
    • SmashCommunity: a metagenomic annotation and analysis tool
    • Arumugam M, Harrington ED, Foerstner KU, Raes J, Bork P, SmashCommunity: a metagenomic annotation and analysis tool. Bioinformatics [Internet]. 2010 Dec 1 [cited 2014 Jan 23];26(23):2977–8. http://bioinformatics.oxfordjournals.org/content/26/23/2977.long doi: 10.1093/bioinformatics/btq536 20959381
    • (2010) Bioinformatics , vol.26 , Issue.23 , pp. 2977-2978
    • Arumugam, M.1    Harrington, E.D.2    Foerstner, K.U.3    Raes, J.4    Bork, P.5
  • 10
    • 84867634981 scopus 로고    scopus 로고
    • MOCAT: a metagenomics assembly and gene prediction toolkit. PLoS One [Internet]
    • Kultima JR, Sunagawa S, Li J, Chen W, Chen H, Mende DR, et al. MOCAT: a metagenomics assembly and gene prediction toolkit. PLoS One [Internet]. Public Library of Science; 2012 Jan 17 [cited 2015 May 29];7(10):e47656. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047656
    • (2012) Public Library of Science , vol.7 , Issue.10 , pp. e47656
    • Kultima, J.R.1    Sunagawa, S.2    Li, J.3    Chen, W.4    Chen, H.5    Mende, D.R.6
  • 11
    • 80052121849 scopus 로고    scopus 로고
    • CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computing
    • Angiuoli S V, Matalka M, Gussman A, Galens K, Vangala M, Riley DR, et al. CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computing. BMC Bioinformatics [Internet]. 2011 Jan [cited 2012 Feb 29];12:356. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3228541&tool=pmcentrez&rendertype=abstract doi: 10.1186/1471-2105-12-356 21878105
    • (2011) BMC Bioinformatics , vol.12 , pp. 356
    • Angiuoli S, V.1    Matalka, M.2    Gussman, A.3    Galens, K.4    Vangala, M.5    Riley, D.R.6
  • 12
    • 53549118607 scopus 로고    scopus 로고
    • The metagenomics RAST server—a public resource for the automatic phylogenetic and functional analysis of metagenomes
    • Meyer F, Paarmann D, D’Souza M, Olson R, Glass EM, Kubal M, et al. The metagenomics RAST server—a public resource for the automatic phylogenetic and functional analysis of metagenomes. BMC Bioinformatics [Internet]. 2008 Jan [cited 2014 Jan 21];9:386.: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2563014&tool=pmcentrez&rendertype=abstract doi: 10.1186/1471-2105-9-386 18803844
    • (2008) BMC Bioinformatics , vol.9 , pp. 386
    • Meyer, F.1    Paarmann, D.2    D’Souza, M.3    Olson, R.4    Glass, E.M.5    Kubal, M.6
  • 13
    • 75549088819 scopus 로고    scopus 로고
    • MicrobesOnline: an integrated portal for comparative and functional genomics
    • Dehal PS, Joachimiak MP, Price MN, Bates JT, Baumohl JK, Chivian D, et al. MicrobesOnline: an integrated portal for comparative and functional genomics. Nucleic Acids Res [Internet]. 2010 Jan [cited 2015 Feb 25];38(Database issue):D396–400. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2808868&tool=pmcentrez&rendertype=abstract doi: 10.1093/nar/gkp919 19906701
    • (2010) Nucleic Acids Res , vol.38 , pp. D396-400
    • Dehal, P.S.1    Joachimiak, M.P.2    Price, M.N.3    Bates, J.T.4    Baumohl, J.K.5    Chivian, D.6
  • 14
    • 84862024797 scopus 로고    scopus 로고
    • IMG/M: the integrated metagenome data management and comparative analysis system
    • Markowitz VM, Chen I-MA, Chu K, Szeto E, Palaniappan K, Grechkin Y, et al. IMG/M: the integrated metagenome data management and comparative analysis system. Nucleic Acids Res [Internet]. 2012 Jan [cited 2015 Feb 25];40(Database issue):D123–9. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3245048&tool=pmcentrez&rendertype=abstract doi: 10.1093/nar/gkr975 22086953
    • (2012) Nucleic Acids Res , vol.40 , pp. D123-9
    • Markowitz, V.M.1    Chen, I.-M.A.2    Chu, K.3    Szeto, E.4    Palaniappan, K.5    Grechkin, Y.6
  • 15
    • 70349993601 scopus 로고    scopus 로고
    • ShotgunFunctionalizeR: an R-package for functional comparison of metagenomes
    • Kristiansson E, Hugenholtz P, Dalevi D, ShotgunFunctionalizeR: an R-package for functional comparison of metagenomes. Bioinformatics [Internet]. 2009 Oct 15 [cited 2014 Jan 22];25(20):2737–8. http://bioinformatics.oxfordjournals.org/content/25/20/2737.abstract doi: 10.1093/bioinformatics/btp508 19696045
    • (2009) Bioinformatics , vol.25 , Issue.20 , pp. 2737-2738
    • Kristiansson, E.1    Hugenholtz, P.2    Dalevi, D.3
  • 16
    • 84887301559 scopus 로고    scopus 로고
    • Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States
    • Fierer N, Ladau J, Clemente JC, Leff JW, Owens SM, Pollard KS, et al. Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States. Science [Internet]. 2013 Nov 1 [cited 2014 Feb 20];342(6158):621–4. http://www.sciencemag.org/content/342/6158/621.full doi: 10.1126/science.1243768 24179225
    • (2013) Science , vol.342 , Issue.6158 , pp. 621-624
    • Fierer, N.1    Ladau, J.2    Clemente, J.C.3    Leff, J.W.4    Owens, S.M.5    Pollard, K.S.6
  • 17
    • 84862286169 scopus 로고    scopus 로고
    • A framework for human microbiome research
    • HMPA framework for human microbiome research. Nature [Internet]. NIH Public Access; 2012 Jun 14 [cited 2014 Jan 20];486(7402):215–21. http://europepmc.org/articles/PMC3377744/?report=abstract doi: 10.1038/nature11209 22699610
    • (2012) Nature , vol.486 , Issue.7402 , pp. 215-221
  • 18
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature [Internet]. 2010 Mar 4 [cited 2014 Jul 9];464(7285):59–65. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3779803&tool=pmcentrez&rendertype=abstract doi: 10.1038/nature08821 20203603
    • (2010) Nature , vol.464 , Issue.7285 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 19
    • 34249794257 scopus 로고    scopus 로고
    • Use of simulated data sets to evaluate the fidelity of metagenomic processing methods. Nat Methods
    • Mavromatis K, Ivanova N, Barry K, Shapiro H, Goltsman E, McHardy AC, et al. Use of simulated data sets to evaluate the fidelity of metagenomic processing methods. Nat Methods [Internet]. 2007 Jun [cited 2014 Jan 24];4(6):495–500. http://www.ncbi.nlm.nih.gov/pubmed/17468765
    • (2007) Internet] , vol.4 , Issue.6 , pp. 495-500
    • Mavromatis, K.1    Ivanova, N.2    Barry, K.3    Shapiro, H.4    Goltsman, E.5    McHardy, A.C.6
  • 20
    • 40549141418 scopus 로고    scopus 로고
    • Metagenomics: read length matters
    • Wommack KE, Bhavsar J, Ravel J, Metagenomics: read length matters. Appl Environ Microbiol [Internet]. 2008 Mar [cited 2015 Feb 28];74(5):1453–63. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2258652&tool=pmcentrez&rendertype=abstract doi: 10.1128/AEM.02181-07 18192407
    • (2008) Appl Environ Microbiol , vol.74 , Issue.5 , pp. 1453-1463
    • Wommack, K.E.1    Bhavsar, J.2    Ravel, J.3
  • 21
    • 44349136375 scopus 로고    scopus 로고
    • Expected Gene Order Distances and Model Selection in Bacteria
    • Dalevi D, Eriksen N, Expected Gene Order Distances and Model Selection in Bacteria. Bioinformatics [Internet]. 2008 Apr 1; http://bioinformatics.oxfordjournals.org/cgi/content/abstract/24/11/1332
    • (2008) Bioinformatics
    • Dalevi, D.1    Eriksen, N.2
  • 22
    • 84922717073 scopus 로고    scopus 로고
    • Comparative analysis of functional metagenomic annotation and the mappability of short reads
    • Carr R, Borenstein E, Comparative analysis of functional metagenomic annotation and the mappability of short reads. PLoS One [Internet]. 2014 Jan [cited 2015 Feb 28];9(8):e105776. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4141809&tool=pmcentrez&rendertype=abstract doi: 10.1371/journal.pone.0105776 25148512
    • (2014) PLoS One , vol.9 , Issue.8 , pp. e105776
    • Carr, R.1    Borenstein, E.2
  • 23
    • 84867294452 scopus 로고    scopus 로고
    • Sifting through genomes with iterative-sequence clustering produces a large, phylogenetically diverse protein-family resource
    • Sharpton TJ, Jospin G, Wu D, Langille MGI, Pollard KS, Eisen JA, Sifting through genomes with iterative-sequence clustering produces a large, phylogenetically diverse protein-family resource. BMC Bioinformatics [Internet]. 2012 Jan [cited 2014 Feb 14];13(1):264. http://www.biomedcentral.com/1471-2105/13/264
    • (2012) BMC Bioinformatics , vol.13 , Issue.1 , pp. 264
    • Sharpton, T.J.1    Jospin, G.2    Wu, D.3    Langille, M.G.I.4    Pollard, K.S.5    Eisen, J.A.6
  • 24
    • 84855167751 scopus 로고    scopus 로고
    • RAPSearch2: a fast and memory-efficient protein similarity search tool for next-generation sequencing data
    • Zhao Y, Tang H, Ye Y, RAPSearch2: a fast and memory-efficient protein similarity search tool for next-generation sequencing data. Bioinformatics [Internet]. 2012 Jan 1 [cited 2014 Jan 21];28(1):125–6. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3244761&tool=pmcentrez&rendertype=abstract doi: 10.1093/bioinformatics/btr595 22039206
    • (2012) Bioinformatics , vol.28 , Issue.1 , pp. 125-126
    • Zhao, Y.1    Tang, H.2    Ye, Y.3
  • 25
    • 0025183708 scopus 로고
    • Basic local alignment search tool
    • Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ, Basic local alignment search tool. J Mol Biol [Internet]. 1990 Oct 5 [cited 2014 Jul 10];215(3):403–10. http://www.ncbi.nlm.nih.gov/pubmed/2231712 2231712
    • (1990) J Mol Biol , vol.215 , Issue.3 , pp. 403-410
    • Altschul, S.F.1    Gish, W.2    Miller, W.3    Myers, E.W.4    Lipman, D.J.5
  • 26
    • 84865561269 scopus 로고    scopus 로고
    • Gene and translation initiation site prediction in metagenomic sequences
    • Hyatt D, LoCascio PF, Hauser LJ, Uberbacher EC, Gene and translation initiation site prediction in metagenomic sequences. Bioinformatics [Internet]. 2012 Sep 1 [cited 2015 Feb 25];28(17):2223–30. http://www.ncbi.nlm.nih.gov/pubmed/22796954 doi: 10.1093/bioinformatics/bts429 22796954
    • (2012) Bioinformatics , vol.28 , Issue.17 , pp. 2223-2230
    • Hyatt, D.1    LoCascio, P.F.2    Hauser, L.J.3    Uberbacher, E.C.4
  • 27
    • 78651326786 scopus 로고    scopus 로고
    • FragGeneScan: predicting genes in short and error-prone reads
    • Rho M, Tang H, Ye Y, FragGeneScan: predicting genes in short and error-prone reads. Nucleic Acids Res [Internet]. 2010 Nov [cited 2014 Jan 30];38(20):e191. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2978382&tool=pmcentrez&rendertype=abstract doi: 10.1093/nar/gkq747 20805240
    • (2010) Nucleic Acids Res , vol.38 , Issue.20 , pp. e191
    • Rho, M.1    Tang, H.2    Ye, Y.3
  • 28
    • 77955902981 scopus 로고    scopus 로고
    • Ab initio gene identification in metagenomic sequences
    • Zhu W, Lomsadze A, Borodovsky M, Ab initio gene identification in metagenomic sequences. Nucleic Acids Res [Internet]. 2010 Jul 1 [cited 2014 Jan 23];38(12):e132. http://nar.oxfordjournals.org/content/38/12/e132.abstract doi: 10.1093/nar/gkq275 20403810
    • (2010) Nucleic Acids Res , vol.38 , Issue.12 , pp. e132
    • Zhu, W.1    Lomsadze, A.2    Borodovsky, M.3
  • 29
    • 84864201343 scopus 로고    scopus 로고
    • Short-read reading-frame predictors are not created equal: sequence error causes loss of signal
    • Trimble WL, Keegan KP, D’Souza M, Wilke A, Wilkening J, Gilbert J, et al. Short-read reading-frame predictors are not created equal: sequence error causes loss of signal. BMC Bioinformatics [Internet]. 2012 Jan [cited 2014 Jan 28];13(1):183. http://www.biomedcentral.com/1471-2105/13/183
    • (2012) BMC Bioinformatics , vol.13 , Issue.1 , pp. 183
    • Trimble, W.L.1    Keegan, K.P.2    D’Souza, M.3    Wilke, A.4    Wilkening, J.5    Gilbert, J.6
  • 30
    • 68249126127 scopus 로고    scopus 로고
    • Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont
    • McCutcheon JP, McDonald BR, Moran NA, Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont. PLoS Genet [Internet]. 2009 Jul [cited 2015 Feb 25];5(7):e1000565. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2704378&tool=pmcentrez&rendertype=abstract doi: 10.1371/journal.pgen.1000565 19609354
    • (2009) PLoS Genet , vol.5 , Issue.7 , pp. e1000565
    • McCutcheon, J.P.1    McDonald, B.R.2    Moran, N.A.3
  • 31
    • 0035137890 scopus 로고    scopus 로고
    • Endless possibilities: translation termination and stop codon recognition
    • Bertram G, Innes S, Minella O, Richardson J, Stansfield I, Endless possibilities: translation termination and stop codon recognition. Microbiology [Internet]. 2001 Feb [cited 2015 Feb 25];147(Pt 2):255–69. http://www.ncbi.nlm.nih.gov/pubmed/11158343
    • (2001) Microbiology , vol.147 , Issue.2 , pp. 255-269
    • Bertram, G.1    Innes, S.2    Minella, O.3    Richardson, J.4    Stansfield, I.5
  • 32
    • 84887301559 scopus 로고    scopus 로고
    • Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States
    • Fierer N, Ladau J, Clemente JC, Leff JW, Owens SM, Pollard KS, et al. Reconstructing the microbial diversity and function of pre-agricultural tallgrass prairie soils in the United States. Science [Internet]. 2013 Nov 1 [cited 2014 Feb 20];342(6158):621–4. http://www.sciencemag.org/content/342/6158/621.abstract doi: 10.1126/science.1243768 24179225
    • (2013) Science , vol.342 , Issue.6158 , pp. 621-624
    • Fierer, N.1    Ladau, J.2    Clemente, J.C.3    Leff, J.W.4    Owens, S.M.5    Pollard, K.S.6
  • 33
    • 84907028625 scopus 로고    scopus 로고
    • Lambda: the local aligner for massive biological data
    • Hauswedell H, Singer J, Reinert K, Lambda: the local aligner for massive biological data. Bioinformatics [Internet]. 2014 Sep 1 [cited 2015 Feb 25];30(17):i349–55. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4147892&tool=pmcentrez&rendertype=abstract doi: 10.1093/bioinformatics/btu439 25161219
    • (2014) Bioinformatics , vol.30 , Issue.17 , pp. i349-55
    • Hauswedell, H.1    Singer, J.2    Reinert, K.3
  • 34
    • 84875010465 scopus 로고    scopus 로고
    • An artificial functional family filter in homolog searching in next-generation sequencing metagenomics
    • Du R, Mercante D, Fang Z, An artificial functional family filter in homolog searching in next-generation sequencing metagenomics. PLoS One [Internet]. 2013 Jan [cited 2015 Feb 25];8(3):e58669. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3597637&tool=pmcentrez&rendertype=abstract doi: 10.1371/journal.pone.0058669 23516532
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e58669
    • Du, R.1    Mercante, D.2    Fang, Z.3
  • 35
    • 79960713932 scopus 로고    scopus 로고
    • Accurate and fast estimation of taxonomic profiles from metagenomic shotgun sequences
    • Liu B, Gibbons T, Ghodsi M, Treangen T, Pop M, Accurate and fast estimation of taxonomic profiles from metagenomic shotgun sequences. BMC Genomics [Internet]. 2011 Jan [cited 2014 Jan 22];12 Suppl 2(Suppl 2):S4. http://www.biomedcentral.com/1471-2164/12/S2/S4 doi: 10.1186/1471-2164-12-S2-S4 21989143
    • (2011) BMC Genomics , vol.12 , pp. S4
    • Liu, B.1    Gibbons, T.2    Ghodsi, M.3    Treangen, T.4    Pop, M.5
  • 36
    • 84939141968 scopus 로고    scopus 로고
    • Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome
    • Nayfach S, Pollard KS, Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome. Genome Biol [Internet]. 2015 Mar 25 [cited 2015 Mar 25];16(1):51. http://genomebiology.com/2015/16/1/51
    • (2015) Genome Biol , vol.16 , Issue.1 , pp. 51
    • Nayfach, S.1    Pollard, K.S.2
  • 37
    • 80055082271 scopus 로고    scopus 로고
    • Accelerated Profile HMM Searches
    • Eddy SR, Accelerated Profile HMM Searches. PLoS Comput Biol [Internet]. 2011 Oct [cited 2014 Jul 16];7(10):e1002195. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3197634&tool=pmcentrez&rendertype=abstract doi: 10.1371/journal.pcbi.1002195 22039361
    • (2011) PLoS Comput Biol , vol.7 , Issue.10 , pp. e1002195
    • Eddy, S.R.1
  • 38
    • 78649732106 scopus 로고    scopus 로고
    • The taxonomic and functional diversity of microbes at a temperate coastal site: a “multi-omic” study of seasonal and diel temporal variation
    • Gilbert JA, Field D, Swift P, Thomas S, Cummings D, Temperton B, Rodriguez-Valera F, et al. The taxonomic and functional diversity of microbes at a temperate coastal site: a “multi-omic” study of seasonal and diel temporal variation. PLoS One [Internet]. Public Library of Science; 2010 Jan [cited 2013 May 21];5(11):e15545. http://dx.plos.org/10.1371/journal.pone.0015545 doi: 10.1371/journal.pone.0015545 21124740
    • (2010) PLoS One , vol.5 , Issue.11 , pp. e15545
    • Gilbert, J.A.1    Field, D.2    Swift, P.3    Thomas, S.4    Cummings, D.5    Temperton, B.6    Rodriguez-Valera, F.7
  • 39
    • 73349120997 scopus 로고    scopus 로고
    • FIGfams: yet another set of protein families
    • Meyer F, Overbeek R, Rodriguez A, FIGfams: yet another set of protein families. Nucleic Acids Res [Internet]. 2009 Nov [cited 2015 Jan 6];37(20):6643–54. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2777423&tool=pmcentrez&rendertype=abstract doi: 10.1093/nar/gkp698 19762480
    • (2009) Nucleic Acids Res , vol.37 , Issue.20 , pp. 6643-6654
    • Meyer, F.1    Overbeek, R.2    Rodriguez, A.3
  • 40
    • 84905730761 scopus 로고    scopus 로고
    • Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
    • Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sunagawa S, et al. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes. Nat Biotechnol [Internet]. Nature Publishing Group; 2014 Jul 6 [cited 2014 Jul 9];32(8):822–8. http://www.nature.com/nbt/journal/v32/n8/full/nbt.2939.html#supplementary-information doi: 10.1038/nbt.2939 24997787
    • (2014) Nat Biotechnol , vol.32 , Issue.8 , pp. 822-828
    • Nielsen, H.B.1    Almeida, M.2    Juncker, A.S.3    Rasmussen, S.4    Li, J.5    Sunagawa, S.6
  • 41
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
    • Manichanh C, Rigottier-Gois L, Bonnaud E, Gloux K, Pelletier E, Frangeul L, et al. Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach. Gut [Internet]. 2006 Feb 1 [cited 2012 Oct 4];55(2):205–11. http://gut.bmj.com/content/55/2/205 16188921
    • (2006) Gut , vol.55 , Issue.2 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3    Gloux, K.4    Pelletier, E.5    Frangeul, L.6
  • 42
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. Nature Publishing Group; 2010 Mar 4;464(7285):59–65. doi: 10.1038/nature08821 20203603
    • (2010) Nature , vol.464 , Issue.7285 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 43
    • 79959961092 scopus 로고    scopus 로고
    • Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis
    • Lepage P, Häsler R, Spehlmann ME, Rehman A, Zvirbliene A, Begun A, et al. Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis. Gastroenterology [Internet]. 2011 Jul [cited 2015 Apr 3];141(1):227–36. http://www.ncbi.nlm.nih.gov/pubmed/21621540 doi: 10.1053/j.gastro.2011.04.011 21621540
    • (2011) Gastroenterology , vol.141 , Issue.1 , pp. 227-236
    • Lepage, P.1    Häsler, R.2    Spehlmann, M.E.3    Rehman, A.4    Zvirbliene, A.5    Begun, A.6
  • 44
    • 84870322666 scopus 로고    scopus 로고
    • Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn’s disease
    • Erickson AR, Cantarel BL, Lamendella R, Darzi Y, Mongodin EF, Pan C, et al. Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn’s disease. PLoS One [Internet]. Public Library of Science; 2012 Jan 28 [cited 2015 Jun 22];7(11):e49138. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049138 doi: 10.1371/journal.pone.0049138 23209564
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e49138
    • Erickson, A.R.1    Cantarel, B.L.2    Lamendella, R.3    Darzi, Y.4    Mongodin, E.F.5    Pan, C.6
  • 45
    • 84949242242 scopus 로고    scopus 로고
    • Oksanen J, Blanchet FG, Kindt R, Legendre P, Minchin PR, O’Hara RB, et al. vegan: Community Ecology Package [Internet]. 2015. http://cran.r-project.org/package=vegan
  • 46
    • 84866549438 scopus 로고    scopus 로고
    • Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
    • Morgan XC, Tickle TL, Sokol H, Gevers D, Devaney KL, Ward D V, et al. Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biol [Internet]. 2012 Jan [cited 2014 Jan 23];13(9):R79. http://genomebiology.com/2012/13/9/R79 doi: 10.1186/gb-2012-13-9-r79 23013615
    • (2012) Genome Biol , vol.13 , Issue.9 , pp. R79
    • Morgan, X.C.1    Tickle, T.L.2    Sokol, H.3    Gevers, D.4    Devaney, K.L.5    Ward D, V.6
  • 47
    • 33750956239 scopus 로고    scopus 로고
    • Differences between tissue-associated intestinal microfloras of patients with Crohn’s disease and ulcerative colitis
    • Gophna U, Sommerfeld K, Gophna S, Doolittle WF, Veldhuyzen van Zanten SJO, Differences between tissue-associated intestinal microfloras of patients with Crohn’s disease and ulcerative colitis. J Clin Microbiol [Internet]. 2006 Nov [cited 2015 Feb 26];44(11):4136–41. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1698347&tool=pmcentrez&rendertype=abstract 16988016
    • (2006) J Clin Microbiol , vol.44 , Issue.11 , pp. 4136-4141
    • Gophna, U.1    Sommerfeld, K.2    Gophna, S.3    Doolittle, W.F.4    Veldhuyzen van Zanten, S.J.O.5
  • 48
    • 84870824919 scopus 로고    scopus 로고
    • Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn’s but not in ulcerative colitis
    • Hansen R, Russell RK, Reiff C, Louis P, McIntosh F, Berry SH, et al. Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn’s but not in ulcerative colitis. Am J Gastroenterol [Internet]. 2012 Dec [cited 2015 Feb 26];107(12):1913–22. http://www.ncbi.nlm.nih.gov/pubmed/23044767 doi: 10.1038/ajg.2012.335 23044767
    • (2012) Am J Gastroenterol , vol.107 , Issue.12 , pp. 1913-1922
    • Hansen, R.1    Russell, R.K.2    Reiff, C.3    Louis, P.4    McIntosh, F.5    Berry, S.H.6
  • 49
    • 0025145696 scopus 로고
    • A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease
    • Saxon A, Shanahan F, Landers C, Ganz T, Targan S, A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol [Internet]. 1990 Aug [cited 2015 Feb 26];86(2):202–10.: http://www.ncbi.nlm.nih.gov/pubmed/2200820 2200820
    • (1990) J Allergy Clin Immunol , vol.86 , Issue.2 , pp. 202-210
    • Saxon, A.1    Shanahan, F.2    Landers, C.3    Ganz, T.4    Targan, S.5
  • 50
    • 0036242774 scopus 로고    scopus 로고
    • The value of serologic markers in indeterminate colitis: a prospective follow-up study
    • Joossens S, Reinisch W, Vermeire S, Sendid B, Poulain D, Peeters M, et al. The value of serologic markers in indeterminate colitis: a prospective follow-up study. Gastroenterology [Internet]. 2002 May [cited 2015 Feb 26];122(5):1242–7. http://www.ncbi.nlm.nih.gov/pubmed/11984510 11984510
    • (2002) Gastroenterology , vol.122 , Issue.5 , pp. 1242-1247
    • Joossens, S.1    Reinisch, W.2    Vermeire, S.3    Sendid, B.4    Poulain, D.5    Peeters, M.6
  • 51
    • 0033956320 scopus 로고    scopus 로고
    • Colonic bacteria express an ulcerative colitis pANCA-related protein epitope
    • Cohavy O, Bruckner D, Gordon LK, Misra R, Wei B, Eggena ME, et al. Colonic bacteria express an ulcerative colitis pANCA-related protein epitope. Infect Immun [Internet]. 2000 Mar [cited 2015 Feb 26];68(3):1542–8. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=97313&tool=pmcentrez&rendertype=abstract 10678972
    • (2000) Infect Immun , vol.68 , Issue.3 , pp. 1542-1548
    • Cohavy, O.1    Bruckner, D.2    Gordon, L.K.3    Misra, R.4    Wei, B.5    Eggena, M.E.6
  • 52
    • 33746542174 scopus 로고    scopus 로고
    • Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn’s disease
    • Dotan I, Fishman S, Dgani Y, Schwartz M, Karban A, Lerner A, et al. Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn’s disease. Gastroenterology [Internet]. 2006 Aug [cited 2015 Feb 26];131(2):366–78. http://www.ncbi.nlm.nih.gov/pubmed/16890590 16890590
    • (2006) Gastroenterology , vol.131 , Issue.2 , pp. 366-378
    • Dotan, I.1    Fishman, S.2    Dgani, Y.3    Schwartz, M.4    Karban, A.5    Lerner, A.6
  • 53
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn disease
    • Lodes MJ, Cong Y, Elson CO, Mohamath R, Landers CJ, Targan SR, et al. Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest [Internet]. 2004 May [cited 2015 Feb 26];113(9):1296–306. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=398429&tool=pmcentrez&rendertype=abstract 15124021
    • (2004) J Clin Invest , vol.113 , Issue.9 , pp. 1296-1306
    • Lodes, M.J.1    Cong, Y.2    Elson, C.O.3    Mohamath, R.4    Landers, C.J.5    Targan, S.R.6
  • 54
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • Lu Y-C, Yeh W-C, Ohashi PS, LPS/TLR4 signal transduction pathway. Cytokine [Internet]. 2008 May [cited 2014 Jul 11];42(2):145–51. http://www.ncbi.nlm.nih.gov/pubmed/18304834 doi: 10.1016/j.cyto.2008.01.006 18304834
    • (2008) Cytokine , vol.42 , Issue.2 , pp. 145-151
    • Lu, Y.-C.1    Yeh, W.-C.2    Ohashi, P.S.3
  • 55
    • 0029010945 scopus 로고
    • Significance of systemic endotoxaemia in inflammatory bowel disease
    • Gardiner KR, Halliday MI, Barclay GR, Milne L, Brown D, Stephens S, et al. Significance of systemic endotoxaemia in inflammatory bowel disease. Gut [Internet]. 1995 Jun [cited 2015 Feb 26];36(6):897–901. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1382629&tool=pmcentrez&rendertype=abstract 7615280
    • (1995) Gut , vol.36 , Issue.6 , pp. 897-901
    • Gardiner, K.R.1    Halliday, M.I.2    Barclay, G.R.3    Milne, L.4    Brown, D.5    Stephens, S.6
  • 56
    • 77950666046 scopus 로고    scopus 로고
    • Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn’s disease and murine colitis
    • Pasternak BA, D’Mello S, Jurickova II, Han X, Willson T, Flick L, et al. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn’s disease and murine colitis. Inflamm Bowel Dis [Internet]. 2010 May [cited 2015 Feb 26];16(5):856–69. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3052288&tool=pmcentrez&rendertype=abstract doi: 10.1002/ibd.21132 19924809
    • (2010) Inflamm Bowel Dis , vol.16 , Issue.5 , pp. 856-869
    • Pasternak, B.A.1    D’Mello, S.2    Jurickova, I.I.3    Han, X.4    Willson, T.5    Flick, L.6
  • 57
    • 3042521641 scopus 로고    scopus 로고
    • Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis
    • Franchimont D, Vermeire S, El Housni H, Pierik M, Van Steen K, Gustot T, et al. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis. Gut [Internet]. 2004 Jul [cited 2015 Feb 26];53(7):987–92. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1774122&tool=pmcentrez&rendertype=abstract 15194649
    • (2004) Gut , vol.53 , Issue.7 , pp. 987-992
    • Franchimont, D.1    Vermeire, S.2    El Housni, H.3    Pierik, M.4    Van Steen, K.5    Gustot, T.6
  • 58
    • 12344312067 scopus 로고    scopus 로고
    • Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe
    • Arnott IDR, Ho G-T, Nimmo ER, Satsangi J, Toll-like receptor 4 gene in IBD: further evidence for genetic heterogeneity in Europe. Gut [Internet]. 2005 Feb [cited 2015 Feb 26];54(2):308; author reply 309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1774822&tool=pmcentrez&rendertype=abstract 15647200
    • (2005) Gut , vol.54 , Issue.2 , pp. 308
    • Arnott, I.D.R.1    Ho, G.-T.2    Nimmo, E.R.3    Satsangi, J.4
  • 59
    • 35449000411 scopus 로고    scopus 로고
    • Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene? Association study combined with meta-analysis shows strong evidence for association
    • Browning BL, Huebner C, Petermann I, Gearry RB, Barclay ML, Shelling AN, et al. Has toll-like receptor 4 been prematurely dismissed as an inflammatory bowel disease gene? Association study combined with meta-analysis shows strong evidence for association. Am J Gastroenterol [Internet]. 2007 Nov [cited 2015 Feb 26];102(11):2504–12.: http://www.ncbi.nlm.nih.gov/pubmed/17850411 17850411
    • (2007) Am J Gastroenterol , vol.102 , Issue.11 , pp. 2504-2512
    • Browning, B.L.1    Huebner, C.2    Petermann, I.3    Gearry, R.B.4    Barclay, M.L.5    Shelling, A.N.6
  • 60
    • 84923570274 scopus 로고    scopus 로고
    • Mucin glycan foraging in the human gut microbiome
    • Tailford LE, Crost EH, Kavanaugh D, Juge N, Mucin glycan foraging in the human gut microbiome. Front Genet [Internet]. 2015 Jan [cited 2015 Apr 9];6:81. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4365749&tool=pmcentrez&rendertype=abstract doi: 10.3389/fgene.2015.00081 25852737
    • (2015) Front Genet , vol.6 , pp. 81
    • Tailford, L.E.1    Crost, E.H.2    Kavanaugh, D.3    Juge, N.4
  • 61
    • 0027476810 scopus 로고
    • Disruption of sulphated glycosaminoglycans in intestinal inflammation
    • Murch SH, MacDonald TT, Walker-Smith JA, Levin M, Lionetti P, Klein NJ, Disruption of sulphated glycosaminoglycans in intestinal inflammation. Lancet [Internet]. 1993 Mar 20 [cited 2015 Feb 26];341(8847):711–4. http://www.ncbi.nlm.nih.gov/pubmed/8095623 8095623
    • (1993) Lancet , vol.341 , Issue.8847 , pp. 711-714
    • Murch, S.H.1    MacDonald, T.T.2    Walker-Smith, J.A.3    Levin, M.4    Lionetti, P.5    Klein, N.J.6
  • 62
    • 78149283854 scopus 로고    scopus 로고
    • Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria
    • Png CW, Lindén SK, Gilshenan KS, Zoetendal EG, McSweeney CS, Sly LI, et al. Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. Am J Gastroenterol [Internet]. 2010 Nov [cited 2015 Aug 19];105(11):2420–8. http://www.ncbi.nlm.nih.gov/pubmed/20648002 doi: 10.1038/ajg.2010.281 20648002
    • (2010) Am J Gastroenterol , vol.105 , Issue.11 , pp. 2420-2428
    • Png, C.W.1    Lindén, S.K.2    Gilshenan, K.S.3    Zoetendal, E.G.4    McSweeney, C.S.5    Sly, L.I.6
  • 63
    • 79960418118 scopus 로고    scopus 로고
    • Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron
    • Benjdia A, Martens EC, Gordon JI, Berteau O, Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron. J Biol Chem [Internet]. 2011 Jul 22 [cited 2015 Feb 26];286(29):25973–82. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3138274&tool=pmcentrez&rendertype=abstract doi: 10.1074/jbc.M111.228841 21507958
    • (2011) J Biol Chem , vol.286 , Issue.29 , pp. 25973-25982
    • Benjdia, A.1    Martens, E.C.2    Gordon, J.I.3    Berteau, O.4
  • 64
    • 84906871300 scopus 로고    scopus 로고
    • Characterization of glycosaminoglycan (GAG) sulfatases from the human gut symbiont Bacteroides thetaiotaomicron reveals the first GAG-specific bacterial endosulfatase
    • Ulmer JE, Vilén EM, Namburi RB, Benjdia A, Beneteau J, Malleron A, et al. Characterization of glycosaminoglycan (GAG) sulfatases from the human gut symbiont Bacteroides thetaiotaomicron reveals the first GAG-specific bacterial endosulfatase. J Biol Chem [Internet]. 2014 Aug 29 [cited 2015 Feb 26];289(35):24289–303. http://www.ncbi.nlm.nih.gov/pubmed/25002587 doi: 10.1074/jbc.M114.573303 25002587
    • (2014) J Biol Chem , vol.289 , Issue.35 , pp. 24289-24303
    • Ulmer, J.E.1    Vilén, E.M.2    Namburi, R.B.3    Benjdia, A.4    Beneteau, J.5    Malleron, A.6
  • 65
    • 0029240465 scopus 로고
    • Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients
    • Buffinton GD, Doe WF, Altered ascorbic acid status in the mucosa from inflammatory bowel disease patients. Free Radic Res [Internet]. 1995 Feb [cited 2015 Jun 19];22(2):131–43. http://www.ncbi.nlm.nih.gov/pubmed/7704184 7704184
    • (1995) Free Radic Res , vol.22 , Issue.2 , pp. 131-143
    • Buffinton, G.D.1    Doe, W.F.2
  • 66
    • 0001561524 scopus 로고    scopus 로고
    • Colonic antioxidant status in dextran sulfate-induced colitis in mice
    • Blackburn AC, Doe WF, Buffinton GD, Colonic antioxidant status in dextran sulfate-induced colitis in mice. Inflamm Bowel Dis [Internet]. 1997 Jan [cited 2015 Jun 19];3(3):198–203. http://www.ncbi.nlm.nih.gov/pubmed/23282805 23282805
    • (1997) Inflamm Bowel Dis , vol.3 , Issue.3 , pp. 198-203
    • Blackburn, A.C.1    Doe, W.F.2    Buffinton, G.D.3
  • 67
    • 0032700434 scopus 로고    scopus 로고
    • Low levels of glutathione in endoscopic biopsies of patients with Crohn’s colitis: the role of malnutrition
    • Miralles-Barrachina O, Savoye G, Belmonte-Zalar L, Hochain P, Ducrotté P, Hecketsweiler B, et al. Low levels of glutathione in endoscopic biopsies of patients with Crohn’s colitis: the role of malnutrition. Clin Nutr [Internet]. 1999 Oct [cited 2015 Jun 19];18(5):313–7. http://www.ncbi.nlm.nih.gov/pubmed/10601540 10601540
    • (1999) Clin Nutr , vol.18 , Issue.5 , pp. 313-317
    • Miralles-Barrachina, O.1    Savoye, G.2    Belmonte-Zalar, L.3    Hochain, P.4    Ducrotté, P.5    Hecketsweiler, B.6
  • 68
    • 84881556644 scopus 로고    scopus 로고
    • Does active Crohn’s disease have decreased intestinal antioxidant capacity?
    • Pinto MAS, Lopes MS-MS, Bastos STO, Reigada CLL, Dantas RF, Neto JCB, et al. Does active Crohn’s disease have decreased intestinal antioxidant capacity? J Crohns Colitis [Internet]. 2013 Oct [cited 2015 Jun 19];7(9):e358–66. http://www.ncbi.nlm.nih.gov/pubmed/23523266 doi: 10.1016/j.crohns.2013.02.010 23523266
    • (2013) J Crohns Colitis , vol.7 , Issue.9 , pp. e358-66
    • Pinto, M.A.S.1    Lopes, M.S.-M.S.2    Bastos, S.T.O.3    Reigada, C.L.L.4    Dantas, R.F.5    Neto, J.C.B.6
  • 69
    • 0027959253 scopus 로고
    • Oxidants and free radicals in inflammatory bowel disease
    • Grisham MB, Oxidants and free radicals in inflammatory bowel disease. Lancet [Internet]. 1994 Sep 24 [cited 2015 Jun 14];344(8926):859–61. http://www.ncbi.nlm.nih.gov/pubmed/7916405 7916405
    • (1994) Lancet , vol.344 , Issue.8926 , pp. 859-861
    • Grisham, M.B.1
  • 70
    • 84899988992 scopus 로고    scopus 로고
    • Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases
    • Bhattacharyya A, Chattopadhyay R, Mitra S, Crowe SE, Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. Physiol Rev [Internet]. 2014 Apr [cited 2015 Jun 19];94(2):329–54. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4044300&tool=pmcentrez&rendertype=abstract doi: 10.1152/physrev.00040.2012 24692350
    • (2014) Physiol Rev , vol.94 , Issue.2 , pp. 329-354
    • Bhattacharyya, A.1    Chattopadhyay, R.2    Mitra, S.3    Crowe, S.E.4
  • 71
    • 49949117379 scopus 로고    scopus 로고
    • Altered status of antioxidant vitamins and fatty acids in patients with inactive inflammatory bowel disease
    • Hengstermann S, Valentini L, Schaper L, Buning C, Koernicke T, Maritschnegg M, et al. Altered status of antioxidant vitamins and fatty acids in patients with inactive inflammatory bowel disease. Clin Nutr [Internet]. 2008 Aug [cited 2015 Jun 24];27(4):571–8. http://www.ncbi.nlm.nih.gov/pubmed/18316141 doi: 10.1016/j.clnu.2008.01.007 18316141
    • (2008) Clin Nutr , vol.27 , Issue.4 , pp. 571-578
    • Hengstermann, S.1    Valentini, L.2    Schaper, L.3    Buning, C.4    Koernicke, T.5    Maritschnegg, M.6
  • 72
    • 0033789463 scopus 로고    scopus 로고
    • Homocysteine in inflammatory bowel disease: a risk factor for thromboembolic complications?
    • Oldenburg B, Fijnheer R, van der Griend R, vanBerge-Henegouwen GP, Koningsberger JC, Homocysteine in inflammatory bowel disease: a risk factor for thromboembolic complications? Am J Gastroenterol [Internet]. 2000 Oct [cited 2015 Feb 27];95(10):2825–30. http://www.ncbi.nlm.nih.gov/pubmed/11051355 11051355
    • (2000) Am J Gastroenterol , vol.95 , Issue.10 , pp. 2825-2830
    • Oldenburg, B.1    Fijnheer, R.2    van der Griend, R.3    vanBerge-Henegouwen, G.P.4    Koningsberger, J.C.5
  • 73
    • 0034933207 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study
    • Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M, Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study. Am J Gastroenterol [Internet]. 2001 Jul [cited 2015 Feb 7];96(7):2143–9. http://www.ncbi.nlm.nih.gov/pubmed/11467646 11467646
    • (2001) Am J Gastroenterol , vol.96 , Issue.7 , pp. 2143-2149
    • Romagnuolo, J.1    Fedorak, R.N.2    Dias, V.C.3    Bamforth, F.4    Teltscher, M.5
  • 74
    • 42449117676 scopus 로고    scopus 로고
    • Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications
    • Erzin Y, Uzun H, Celik AF, Aydin S, Dirican A, Uzunismail H, Hyperhomocysteinemia in inflammatory bowel disease patients without past intestinal resections: correlations with cobalamin, pyridoxine, folate concentrations, acute phase reactants, disease activity, and prior thromboembolic complications. J Clin Gastroenterol [Internet]. Jan [cited 2015 Feb 27];42(5):481–6. http://www.ncbi.nlm.nih.gov/pubmed/18344891
    • (2015) J Clin Gastroenterol , vol.42 , Issue.5 , pp. 481-486
    • Erzin, Y.1    Uzun, H.2    Celik, A.F.3    Aydin, S.4    Dirican, A.5    Uzunismail, H.6
  • 75
    • 77955413734 scopus 로고    scopus 로고
    • Serum vitamin B12 and folate status in patients with inflammatory bowel diseases
    • Yakut M, Ustün Y, Kabaçam G, Soykan I, Serum vitamin B12 and folate status in patients with inflammatory bowel diseases. Eur J Intern Med [Internet]. 2010 Aug [cited 2015 Feb 27];21(4):320–3. http://www.ncbi.nlm.nih.gov/pubmed/20603044 doi: 10.1016/j.ejim.2010.05.007 20603044
    • (2010) Eur J Intern Med , vol.21 , Issue.4 , pp. 320-323
    • Yakut, M.1    Ustün, Y.2    Kabaçam, G.3    Soykan, I.4
  • 76
    • 84896092821 scopus 로고    scopus 로고
    • The treatment-naive microbiome in new-onset Crohn’s disease
    • Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, et al. The treatment-naive microbiome in new-onset Crohn’s disease. Cell Host Microbe [Internet]. 2014 Mar 12 [cited 2014 Jul 10];15(3):382–92. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=4059512&tool=pmcentrez&rendertype=abstract doi: 10.1016/j.chom.2014.02.005 24629344
    • (2014) Cell Host Microbe , vol.15 , Issue.3 , pp. 382-392
    • Gevers, D.1    Kugathasan, S.2    Denson, L.A.3    Vázquez-Baeza, Y.4    Van Treuren, W.5    Ren, B.6
  • 77
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy human microbiome
    • HMPStructure, function and diversity of the healthy human microbiome. Nature [Internet]. 2012 Jun 14 [cited 2014 Jan 20];486(7402):207–14. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3564958&tool=pmcentrez&rendertype=abstract doi: 10.1038/nature11234 22699609
    • (2012) Nature , vol.486 , Issue.7402 , pp. 207-214
  • 78
    • 84871732071 scopus 로고    scopus 로고
    • Genomic variation landscape of the human gut microbiome
    • Schloissnig S, Arumugam M, Sunagawa S, Mitreva M, Tap J, Zhu A, et al. Genomic variation landscape of the human gut microbiome. Nature [Internet]. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.; 2013 Jan 3 [cited 2014 Jan 20];493(7430):45–50. http://dx.doi.org/10.1038/nature11711 doi: 10.1038/nature11711 23222524
    • (2013) Nature , vol.493 , Issue.7430 , pp. 45-50
    • Schloissnig, S.1    Arumugam, M.2    Sunagawa, S.3    Mitreva, M.4    Tap, J.5    Zhu, A.6
  • 79
    • 69949116874 scopus 로고    scopus 로고
    • IMG ER: a system for microbial genome annotation expert review and curation
    • Markowitz VM, Mavromatis K, Ivanova NN, Chen I- MA, Chu K, Kyrpides NC, IMG ER: a system for microbial genome annotation expert review and curation. Bioinformatics [Internet]. 2009 Sep 1 [cited 2015 Feb 27];25(17):2271–8. http://www.ncbi.nlm.nih.gov/pubmed/19561336 doi: 10.1093/bioinformatics/btp393 19561336
    • (2009) Bioinformatics , vol.25 , Issue.17 , pp. 2271-2278
    • Markowitz, V.M.1    Mavromatis, K.2    Ivanova, N.N.3    Chen I-, M.A.4    Chu, K.5    Kyrpides, N.C.6
  • 80
    • 84863190624 scopus 로고    scopus 로고
    • Grinder: a versatile amplicon and shotgun sequence simulator
    • Angly FE, Willner D, Rohwer F, Hugenholtz P, Tyson GW, Grinder: a versatile amplicon and shotgun sequence simulator. Nucleic Acids Res [Internet]. 2012 Jul [cited 2014 Nov 3];40(12):e94. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3384353&tool=pmcentrez&rendertype=abstract doi: 10.1093/nar/gks251 22434876
    • (2012) Nucleic Acids Res , vol.40 , Issue.12 , pp. e94
    • Angly, F.E.1    Willner, D.2    Rohwer, F.3    Hugenholtz, P.4    Tyson, G.W.5
  • 81
    • 84865591846 scopus 로고    scopus 로고
    • A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers
    • Quail MA, Smith M, Coupland P, Otto TD, Harris SR, Connor TR, et al. A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers. BMC Genomics [Internet]. 2012 Jan [cited 2014 Jul 9];13:341. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3431227&tool=pmcentrez&rendertype=abstract doi: 10.1186/1471-2164-13-341 22827831
    • (2012) BMC Genomics , vol.13 , pp. 341
    • Quail, M.A.1    Smith, M.2    Coupland, P.3    Otto, T.D.4    Harris, S.R.5    Connor, T.R.6
  • 82
    • 0034201441 scopus 로고    scopus 로고
    • EMBOSS: The European Molecular Biology Open Software Suite
    • Rice P, Longden I, Bleasby A, EMBOSS: The European Molecular Biology Open Software Suite. Trends Genet [Internet]. 2000 Jun [cited 2014 Jan 28];16(6):276–7. http://www.sciencedirect.com/science/article/pii/S0168952500020242 10827456
    • (2000) Trends Genet , vol.16 , Issue.6 , pp. 276-277
    • Rice, P.1    Longden, I.2    Bleasby, A.3
  • 83
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R, Statistical significance for genomewide studies. Proc Natl Acad Sci U S A [Internet]. 2003 Aug 5 [cited 2014 Aug 17];100(16):9440–5. http://www.pnas.org/content/100/16/9440.short 12883005
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.16 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2


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