Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

Neuroscience

Volumn 285, Issue , 2015, Pages 70-80

  Dong, H ^a   Li, R ^b   Yu, C ^a   Xu, T ^a   Zhang, X ^a   Dong, M ^a  

^a QIQIHAR MEDICAL UNIVERSITY   (China)

^b Hongqi Hospital of Mudanjiang Medical College   (China)

Author keywords

Apoptosis; Oxidative stress; Paeonia lactiflora Pall; Parkinson's disease

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CYTOCHROME C; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDOPAMINE; PAEONIFLORIN; PROTEIN KINASE B; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTIOXIDANT; GLUCOSIDE; NEUROPROTECTIVE AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TERPENE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CYTOSOL; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; CYTOCHROMES C; CYTOSOL; GLUCOSIDES; MONOTERPENES; NADPH OXIDASE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OXIDATIVE STRESS; OXIDOPAMINE; PC12 CELLS; PROTEIN KINASE C-DELTA; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84949114983     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.11.008     Document Type: Article

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