Paeoniflorin Protects against Ischemia-Induced Brain Damages in Rats via Inhibiting MAPKs/NF-κB-Mediated Inflammatory Responses

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Guo, Ruo Bing ^a   Wang, Guo Feng ^b   Zhao, An Peng ^a   Gu, Jun ^a   Sun, Xiu Lan ^a   Hu, Gang ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b JINAN MILITARY GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PAEONIFLORIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN DAMAGE; BRAIN ISCHEMIA; CELL LOSS; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; IN VITRO STUDY; INFLAMMATION; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; BENZOATES; BRAIN; BRAIN ISCHEMIA; BRIDGED COMPOUNDS; CEREBRAL INFARCTION; CYCLOOXYGENASE 2; CYTOCHROMES C; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUCOSIDES; HIPPOCAMPUS; INFLAMMATION; INTERLEUKIN-1BETA; LIPOXYGENASE; MALE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 84869109672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049701     Document Type: Article

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