Kinetic distribution of paeoniflorin in cortex of normal and cerebral ischemia-reperfusion rats after intravenous administration of Paeoniae radix extract

Biomedical Chromatography

Volumn 20, Issue 12, 2006, Pages 1283-1288

  Cao, Chunai ^a   He, Xihui ^b   Wang, Wei ^a   Zhang, Lujun ^a   Lin, Han ^a   Du, Lijun ^a  

^a TSINGHUA UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Blood brain barrier; Cortex; HPLC; Ischemia reperfusion; Paeoniflorin

Indexed keywords

BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

BLOOD-BRAIN BARRIER; CEREBRAL ISCHEMIA-REPERFUSION; CORTEXES; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC; INTRAVENOUS ADMINISTRATION; ISCHAEMIA-REPERFUSION; PAEONIAE RADIXES; PAEONIFLORIN; PERFORMANCE; TIME COURSE;

RATS;

PAEONIA RADIX; PAEONIFLORIN; PENTOXIFYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG STABILITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEAN RESIDENCE TIME; NONHUMAN; RAT; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS;

RATTUS;

EID: 33846208637     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.658     Document Type: Article

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