Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H2O2-induced neural progenitor cell injury

Neuroscience

Volumn 240, Issue , 2013, Pages 54-62

  Wu, Y M ^a   Jin, R ^b   Yang, L ^a   Zhang, J ^a   Yang, Q ^a   Guo, Y Y ^a   Li, X B ^a   Liu, S B ^a   Luo, X X ^a   Zhao, M G ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antioxidant; Apoptosis; H2O2; Neural progenitor cells; Paeoniflorin; Phosphatidylinositol 3 kinase (PI3K) protein kinase B (Akt 1) pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; HYDROGEN PEROXIDE; PAEONIFLORIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; STEM CELL;

ANALYSIS OF VARIANCE; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BENZOATES; BRAIN; BRIDGED COMPOUNDS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLUCOSIDES; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; INTERMEDIATE FILAMENT PROTEINS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROPROTECTIVE AGENTS; OXIDANTS; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84875799405     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.02.037     Document Type: Article

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