-
1
-
-
77955332763
-
+ and acidic damage via autophagic pathway
-
20558269 10.1016/j.jep.2010.06.009 1:CAS:528:DC%2BC3cXpvVKrs7c%3D
-
+ and acidic damage via autophagic pathway. J Ethnopharmacol 131(1):122-129
-
(2010)
J Ethnopharmacol
, vol.131
, Issue.1
, pp. 122-129
-
-
Cao, B.Y.1
Yang, Y.P.2
Luo, W.F.3
Mao, C.J.4
Han, R.5
Sun, X.6
Cheng, J.7
Liu, C.F.8
-
2
-
-
1542616703
-
Proteins of the bcl-2 family in apoptosis signalling: From mechanistic insights to therapeutic opportunities
-
15008953 10.1111/j.1440-1681.2004.03975.x 1:CAS:528:DC%2BD2cXitlWntb0%3D
-
Chan SL, Yu VC (2004) Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities. Clin Exp Pharmacol Physiol 31(3):119-128
-
(2004)
Clin Exp Pharmacol Physiol
, vol.31
, Issue.3
, pp. 119-128
-
-
Chan, S.L.1
Yu, V.C.2
-
3
-
-
15244352198
-
Emerging role for ERK as a key regulator of neuronal apoptosis
-
Cheung EC, Slack RS (2004) Emerging role for ERK as a key regulator of neuronal apoptosis. Sci STKE 2004 (251):PE45
-
(2004)
Sci STKE
, Issue.251
-
-
Cheung, E.C.1
Slack, R.S.2
-
4
-
-
56449116314
-
Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade
-
19330070 10.3390/ijms9112217 1:CAS:528:DC%2BD1cXhsVyhsbbE
-
Cho JY, Park J (2008) Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade. Int J Mol Sci 9(11):2217-2230
-
(2008)
Int J Mol Sci
, vol.9
, Issue.11
, pp. 2217-2230
-
-
Cho, J.Y.1
Park, J.2
-
5
-
-
0027374638
-
A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′- tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1)
-
8250945 10.1006/bbrc.1993.2438 1:CAS:528:DyaK2cXis1Oktg%3D%3D
-
Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C (1993) A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′- tetrachloro-1,1′,3,3′-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Biochem Biophys Res Commun 197(1):40-45
-
(1993)
Biochem Biophys Res Commun
, vol.197
, Issue.1
, pp. 40-45
-
-
Cossarizza, A.1
Baccarani-Contri, M.2
Kalashnikova, G.3
Franceschi, C.4
-
6
-
-
84863218983
-
Mitochondrial Ca(2+) and apoptosis
-
22480931 10.1016/j.ceca.2012.02.008 1:CAS:528:DC%2BC38XltVejtrs%3D
-
Giorgi C, Baldassari F, Bononi A, Bonora M, De Marchi E, Marchi S, Missiroli S, Patergnani S, Rimessi A, Suski JM, Wieckowski MR, Pinton P (2012) Mitochondrial Ca(2+) and apoptosis. Cell Calcium 52(1):36-43
-
(2012)
Cell Calcium
, vol.52
, Issue.1
, pp. 36-43
-
-
Giorgi, C.1
Baldassari, F.2
Bononi, A.3
Bonora, M.4
De Marchi, E.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Rimessi, A.9
Suski, J.M.10
Wieckowski, M.R.11
Pinton, P.12
-
7
-
-
1542318100
-
Mitochondrial function in apoptotic neuronal cell death
-
15038600 10.1023/B:NERE.0000014823.74782.b7 1:CAS:528: DC%2BD2cXpslWhsg%3D%3D
-
Haeberlein SL (2004) Mitochondrial function in apoptotic neuronal cell death. Neurochem Res 29(3):521-530
-
(2004)
Neurochem Res
, vol.29
, Issue.3
, pp. 521-530
-
-
Haeberlein, S.L.1
-
8
-
-
33749009587
-
BCL-xL regulates synaptic plasticity
-
16960143 10.1124/mi.6.4.7 1:CAS:528:DC%2BD28XhtVyqurbO
-
Jonas E (2006) BCL-xL regulates synaptic plasticity. Mol Interv 6(4):208-222
-
(2006)
Mol Interv
, vol.6
, Issue.4
, pp. 208-222
-
-
Jonas, E.1
-
9
-
-
0036254633
-
JNK and ERK signaling pathways in multistage mouse carcinogenesis: Studies in the inhibition of signaling cascades as a means to understand their in vivo biological role
-
12014647 1:CAS:528:DC%2BD38XktF2nuro%3D
-
Katsanakis KD, Owen C, Zoumpourlis V (2002) JNK and ERK signaling pathways in multistage mouse carcinogenesis: studies in the inhibition of signaling cascades as a means to understand their in vivo biological role. Anticancer Res 22(2A):755-759
-
(2002)
Anticancer Res
, vol.22
, Issue.2 A
, pp. 755-759
-
-
Katsanakis, K.D.1
Owen, C.2
Zoumpourlis, V.3
-
10
-
-
0026662769
-
Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]
-
1368802 10.1016/0168-1656(92)90158-6 1:CAS:528:DyaK38XmsVOqsr8%3D
-
Legrand C, Bour JM, Jacob C, Capiaumont J, Martial A, Marc A, Wudtke M, Kretzmer G, Demangel C, Duval D et al (1992) Lactate dehydrogenase (LDH) activity of the cultured eukaryotic cells as marker of the number of dead cells in the medium [corrected]. J Biotechnol 25(3):231-243
-
(1992)
J Biotechnol
, vol.25
, Issue.3
, pp. 231-243
-
-
Legrand, C.1
Bour, J.M.2
Jacob, C.3
Capiaumont, J.4
Martial, A.5
Marc, A.6
Wudtke, M.7
Kretzmer, G.8
Demangel, C.9
Duval, D.10
-
11
-
-
33845221922
-
Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases
-
17097910 10.1016/j.biocel.2006.09.011 1:CAS:528:DC%2BD28Xht12ktLjN
-
Li CR, Zhou Z, Zhu D, Sun YN, Dai JM, Wang SQ (2007) Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases. Int J Biochem Cell Biol 39(2):426-438
-
(2007)
Int J Biochem Cell Biol
, vol.39
, Issue.2
, pp. 426-438
-
-
Li, C.R.1
Zhou, Z.2
Zhu, D.3
Sun, Y.N.4
Dai, J.M.5
Wang, S.Q.6
-
12
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
12851486 10.4161/cc.2.4.433 1:CAS:528:DC%2BD3sXnvVyjsLY%3D
-
Liang J, Slingerland JM (2003) Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2(4):339-345
-
(2003)
Cell Cycle
, vol.2
, Issue.4
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
13
-
-
34248597746
-
Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease
-
17451897 10.1016/j.jep.2007.03.022 1:CAS:528:DC%2BD2sXls1Wrs7k%3D
-
Liu DZ, Zhu J, Jin DZ, Zhang LM, Ji XQ, Ye Y, Tang CP, Zhu XZ (2007) Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease. J Ethnopharmacol 112(2):327-332
-
(2007)
J Ethnopharmacol
, vol.112
, Issue.2
, pp. 327-332
-
-
Liu, D.Z.1
Zhu, J.2
Jin, D.Z.3
Zhang, L.M.4
Ji, X.Q.5
Ye, Y.6
Tang, C.P.7
Zhu, X.Z.8
-
14
-
-
0038481271
-
Mitochondrial regulation of apoptosis
-
12750442 1:CAS:528:DC%2BD3sXltlSgsrc%3D
-
Mayer B, Oberbauer R (2003) Mitochondrial regulation of apoptosis. News Physiol Sci 18:89-94
-
(2003)
News Physiol Sci
, vol.18
, pp. 89-94
-
-
Mayer, B.1
Oberbauer, R.2
-
15
-
-
0029186517
-
Use of cultured neurons and neuronal cell lines to study morphological, biochemical, and molecular changes occurring in cell death
-
7609653 10.1016/S0091-679X(08)61931-7 1:CAS:528:DyaK2MXntVSntLk%3D
-
Mills JC, Wang S, Erecinska M, Pittman RN (1995) Use of cultured neurons and neuronal cell lines to study morphological, biochemical, and molecular changes occurring in cell death. Methods Cell Biol 46:217-242
-
(1995)
Methods Cell Biol
, vol.46
, pp. 217-242
-
-
Mills, J.C.1
Wang, S.2
Erecinska, M.3
Pittman, R.N.4
-
16
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65(1-2):55-63
-
(1983)
J Immunol Methods
, vol.65
, Issue.1-2
, pp. 55-63
-
-
Mosmann, T.1
-
17
-
-
70449536507
-
Mitochondria in neurodegenerative disorders: Regulation of the redox state and death signaling leading to neuronal death and survival
-
19763773 10.1007/s00702-009-0309-7 1:CAS:528:DC%2BD1MXhtlKhsbzM
-
Naoi M, Maruyama W, Yi H, Inaba K, Akao Y, Shamoto-Nagai M (2009) Mitochondria in neurodegenerative disorders: regulation of the redox state and death signaling leading to neuronal death and survival. J Neural Transm 116(11):1371-1381
-
(2009)
J Neural Transm
, vol.116
, Issue.11
, pp. 1371-1381
-
-
Naoi, M.1
Maruyama, W.2
Yi, H.3
Inaba, K.4
Akao, Y.5
Shamoto-Nagai, M.6
-
18
-
-
77952573915
-
Deficiency in poly(ADP-ribose) polymerase-1 (PARP-1) accelerates aging and spontaneous carcinogenesis in mice
-
Piskunova TS, Yurova MN, Ovsyannikov AI, Semenchenko AV, Zabezhinski MA, Popovich IG, Wang ZQ, Anisimov VN (2008) Deficiency in poly(ADP-ribose) polymerase-1 (PARP-1) accelerates aging and spontaneous carcinogenesis in mice. Curr Gerontol Geriatr Res:754190
-
(2008)
Curr Gerontol Geriatr Res
, pp. 754190
-
-
Piskunova, T.S.1
Yurova, M.N.2
Ovsyannikov, A.I.3
Semenchenko, A.V.4
Ma, Z.5
Popovich, I.G.6
Wang, Z.Q.7
Anisimov, V.N.8
-
19
-
-
15844397278
-
Neurotoxins and neurotoxic species implicated in neurodegeneration
-
15639792 10.1007/BF03033456
-
Segura Aguilar J, Kostrzewa RM (2004) Neurotoxins and neurotoxic species implicated in neurodegeneration. Neurotox Res 6(7-8):615-630
-
(2004)
Neurotox Res
, vol.6
, Issue.7-8
, pp. 615-630
-
-
Segura Aguilar, J.1
Kostrzewa, R.M.2
-
20
-
-
33644832098
-
Dissociated primary nerve cell cultures as models for assessment of neurotoxicity
-
16257146 10.1016/j.toxlet.2005.09.033 1:CAS:528:DC%2BD28Xit1Cnt7w%3D
-
Silva RF, Falcao AS, Fernandes A, Gordo AC, Brito MA, Brites D (2006) Dissociated primary nerve cell cultures as models for assessment of neurotoxicity. Toxicol Lett 163(1):1-9
-
(2006)
Toxicol Lett
, vol.163
, Issue.1
, pp. 1-9
-
-
Silva, R.F.1
Falcao, A.S.2
Fernandes, A.3
Gordo, A.C.4
Brito, M.A.5
Brites, D.6
-
21
-
-
77953542201
-
Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species
-
20433817 10.1016/j.cbi.2010.04.012 1:CAS:528:DC%2BC3cXntVeltbw%3D
-
Soletti RC, del Barrio L, Daffre S, Miranda A, Borges HL, Moura-Neto V, Lopez MG, Gabilan NH (2010) Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species. Chem Biol Interact 186(2):135-143
-
(2010)
Chem Biol Interact
, vol.186
, Issue.2
, pp. 135-143
-
-
Soletti, R.C.1
Del Barrio, L.2
Daffre, S.3
Miranda, A.4
Borges, H.L.5
Moura-Neto, V.6
Lopez, M.G.7
Gabilan, N.H.8
-
22
-
-
0025893237
-
Inhibitory effect of peony root extract on pentylenetetrazol-induced EEG power spectrum changes and extracellular calcium concentration changes in rat cerebral cortex
-
1943164 10.1016/0378-8741(91)90174-C 1:STN:280:DyaK38%2FkslGiug%3D%3D
-
Sugaya A, Suzuki T, Sugaya E, Yuyama N, Yasuda K, Tsuda T (1991) Inhibitory effect of peony root extract on pentylenetetrazol-induced EEG power spectrum changes and extracellular calcium concentration changes in rat cerebral cortex. J Ethnopharmacol 33(1-2):159-167
-
(1991)
J Ethnopharmacol
, vol.33
, Issue.1-2
, pp. 159-167
-
-
Sugaya, A.1
Suzuki, T.2
Sugaya, E.3
Yuyama, N.4
Yasuda, K.5
Tsuda, T.6
-
23
-
-
0035166616
-
The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
-
11145972 10.1046/j.1471-4159.2001.00054.x 1:CAS:528:DC%2BD3MXhtVGls7w%3D
-
Sweatt JD (2001) The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76(1):1-10
-
(2001)
J Neurochem
, vol.76
, Issue.1
, pp. 1-10
-
-
Sweatt, J.D.1
-
24
-
-
0029043888
-
A novel assay for apoptosis. flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin v
-
7622868 10.1016/0022-1759(95)00072-I 1:CAS:528:DyaK2MXnt1Ojsbo%3D
-
Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995) A novel assay for apoptosis. flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 184(1):39-51
-
(1995)
J Immunol Methods
, vol.184
, Issue.1
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
25
-
-
84862922033
-
Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro
-
22219646
-
Wankun X, Wenzhen Y, Min Z, Weiyan Z, Huan C, Wei D, Lvzhen H, Xu Y, Xiaoxin L (2011) Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro. Mol Vis 17:3512-3522
-
(2011)
Mol Vis
, vol.17
, pp. 3512-3522
-
-
Wankun, X.1
Wenzhen, Y.2
Min, Z.3
Weiyan, Z.4
Huan, C.5
Wei, D.6
Lvzhen, H.7
Xu, Y.8
Xiaoxin, L.9
-
26
-
-
0022079839
-
A review on the pharmacology of Paeonia lactiflora and its chemical components
-
2934174 1:STN:280:DyaL28%2FnvFOntA%3D%3D
-
Wu CF (1985) A review on the pharmacology of Paeonia lactiflora and its chemical components. Zhong Yao Tong Bao 10(6):43-45
-
(1985)
Zhong Yao Tong Bao
, vol.10
, Issue.6
, pp. 43-45
-
-
Wu, C.F.1
-
27
-
-
75449094617
-
Chemical constituents and bioactivities of plants from the genus Paeonia
-
20087998 10.1002/cbdv.200800148 1:CAS:528:DC%2BC3cXhtVKhu7k%3D
-
Wu SH, Wu DG, Chen YW (2010) Chemical constituents and bioactivities of plants from the genus Paeonia. Chem Biodivers 7(1):90-104
-
(2010)
Chem Biodivers
, vol.7
, Issue.1
, pp. 90-104
-
-
Wu, S.H.1
Wu, D.G.2
Chen, Y.W.3
-
28
-
-
27744529453
-
Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats
-
16137717 10.1016/j.lfs.2005.04.069
-
Xiao L, Wang YZ, Liu J, Luo XT, Ye Y, Zhu XZ (2005) Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. Life Sci 78(4):413-420
-
(2005)
Life Sci
, vol.78
, Issue.4
, pp. 413-420
-
-
Xiao, L.1
Wang, Y.Z.2
Liu, J.3
Luo, X.T.4
Ye, Y.5
Zhu, X.Z.6
-
29
-
-
0034641936
-
Apoptosis in the nervous system
-
11048732 10.1038/35037739 1:CAS:528:DC%2BD3cXnsFWrsbY%3D
-
Yuan J, Yankner BA (2000) Apoptosis in the nervous system. Nature 407(6805):802-809
-
(2000)
Nature
, vol.407
, Issue.6805
, pp. 802-809
-
-
Yuan, J.1
Yankner, B.A.2
-
30
-
-
0034765530
-
Systematic review of prediction of poor outcome in anoxic-ischaemic coma with biochemical markers of brain damage
-
11685309 10.1007/s001340101076 1:STN:280:DC%2BD3MnhtVeltg%3D%3D
-
Zandbergen EG, de Haan RJ, Hijdra A (2001) Systematic review of prediction of poor outcome in anoxic-ischaemic coma with biochemical markers of brain damage. Intensive Care Med 27(10):1661-1667
-
(2001)
Intensive Care Med
, vol.27
, Issue.10
, pp. 1661-1667
-
-
Zandbergen, E.G.1
De Haan, R.J.2
Hijdra, A.3
-
31
-
-
70349210047
-
Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A(1) receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway
-
19664651 10.1016/j.pbb.2009.07.013 1:CAS:528:DC%2BD1MXhtFyqurnN
-
Zhang XJ, Chen HL, Li Z, Zhang HQ, Xu HX, Sung JJ, Bian ZX (2009) Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A(1) receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway. Pharmacol Biochem Behav 94(1):88-97
-
(2009)
Pharmacol Biochem Behav
, vol.94
, Issue.1
, pp. 88-97
-
-
Zhang, X.J.1
Chen, H.L.2
Li, Z.3
Zhang, H.Q.4
Xu, H.X.5
Sung, J.J.6
Bian, Z.X.7
|