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Volumn 126, Issue 22, 2015, Pages 2502-2510

NBS1 is required for macrophage homeostasis and functional activity in mice

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; CELL DNA; COLONY STIMULATING FACTOR 1; CYTOKINE; NIBRIN; REACTIVE OXYGEN METABOLITE; ZYMOSAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA LIGASE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MRE11A PROTEIN, MOUSE; NIJMEGEN BREAKAGE SYNDROME 1 PROTEIN, MOUSE; NUCLEAR PROTEIN;

EID: 84948834256     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-04-637371     Document Type: Article
Times cited : (35)

References (55)
  • 1
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature. 2009;461(7267):1071-1078.
    • (2009) Nature , vol.461 , Issue.7267 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 2
    • 79953776915 scopus 로고    scopus 로고
    • DNA doublestrand break signaling and human disorders
    • Bohgaki T, Bohgaki M, Hakem R. DNA doublestrand break signaling and human disorders. Genome Integr. 2010;1(1):15.
    • (2010) Genome Integr , vol.1 , Issue.1 , pp. 15
    • Bohgaki, T.1    Bohgaki, M.2    Hakem, R.3
  • 3
    • 84865364870 scopus 로고    scopus 로고
    • Playing the end game: DNA double-strand break repair pathway choice
    • Chapman JR, Taylor MR, Boulton SJ. Playing the end game: DNA double-strand break repair pathway choice. Mol Cell. 2012;47(4):497-510.
    • (2012) Mol Cell , vol.47 , Issue.4 , pp. 497-510
    • Chapman, J.R.1    Taylor, M.R.2    Boulton, S.J.3
  • 5
    • 57349181439 scopus 로고    scopus 로고
    • Working together and apart: The twisted relationship of the Mre11 complex and Chk2 in apoptosis and tumor suppression
    • Stracker TH, Petrini JH. Working together and apart: the twisted relationship of the Mre11 complex and Chk2 in apoptosis and tumor suppression. Cell Cycle. 2008;7(23):3618-3621.
    • (2008) Cell Cycle , vol.7 , Issue.23 , pp. 3618-3621
    • Stracker, T.H.1    Petrini, J.H.2
  • 6
    • 84919346374 scopus 로고    scopus 로고
    • The MRE11 complex: An important source of stress relief
    • Rein K, Stracker TH. The MRE11 complex: an important source of stress relief. Exp Cell Res. 2014;329(1):162-169.
    • (2014) Exp Cell Res , vol.329 , Issue.1 , pp. 162-169
    • Rein, K.1    Stracker, T.H.2
  • 7
    • 78951474460 scopus 로고    scopus 로고
    • The MRE11 complex: Starting from the ends
    • Stracker TH, Petrini JH. The MRE11 complex: starting from the ends. Nat Rev Mol Cell Biol. 2011;12(2):90-103.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.2 , pp. 90-103
    • Stracker, T.H.1    Petrini, J.H.2
  • 8
    • 34249048548 scopus 로고    scopus 로고
    • Distinct domains in Nbs1 regulate irradiationinduced checkpoints and apoptosis
    • Difilippantonio S, Celeste A, Kruhlak MJ, et al. Distinct domains in Nbs1 regulate irradiationinduced checkpoints and apoptosis. J Exp Med. 2007;204(5):1003-1011.
    • (2007) J Exp Med , vol.204 , Issue.5 , pp. 1003-1011
    • Difilippantonio, S.1    Celeste, A.2    Kruhlak, M.J.3
  • 9
    • 0032076190 scopus 로고    scopus 로고
    • Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
    • Varon R, Vissinga C, Platzer M, et al. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell. 1998;93(3):467-476.
    • (1998) Cell , vol.93 , Issue.3 , pp. 467-476
    • Varon, R.1    Vissinga, C.2    Platzer, M.3
  • 10
    • 0032076248 scopus 로고    scopus 로고
    • The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • Carney JP, Maser RS, Olivares H, et al. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell. 1998;93(3):477-486.
    • (1998) Cell , vol.93 , Issue.3 , pp. 477-486
    • Carney, J.P.1    Maser, R.S.2    Olivares, H.3
  • 11
    • 0033710938 scopus 로고    scopus 로고
    • Clinical ascertainment of Nijmegen breakage syndrome (NBS) and prevalence of the major mutation, 657del5, in three Slav populations
    • Varon R, Seemanova E, Chrzanowska K, et al. Clinical ascertainment of Nijmegen breakage syndrome (NBS) and prevalence of the major mutation, 657del5, in three Slav populations. Eur J Hum Genet. 2000;8(11):900-902.
    • (2000) Eur J Hum Genet , vol.8 , Issue.11 , pp. 900-902
    • Varon, R.1    Seemanova, E.2    Chrzanowska, K.3
  • 12
    • 77954731256 scopus 로고    scopus 로고
    • Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients
    • van der Burg M, Pac M, Berkowska MA, et al. Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients. Blood. 2010;115(23):4770-4777.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4770-4777
    • Van Der Burg, M.1    Pac, M.2    Berkowska, M.A.3
  • 13
    • 84866595059 scopus 로고    scopus 로고
    • The defect in humoral immunity in patients with Nijmegen breakage syndrome is explained by defects in peripheral B lymphocyte maturation
    • Piątosa B, van der Burg M, Siewiera K, et al. The defect in humoral immunity in patients with Nijmegen breakage syndrome is explained by defects in peripheral B lymphocyte maturation. Cytometry A. 2012;81(10):835-842.
    • (2012) Cytometry A , vol.81 , Issue.10 , pp. 835-842
    • Piątosa, B.1    Van Der Burg, M.2    Siewiera, K.3
  • 14
    • 0035710839 scopus 로고    scopus 로고
    • Molecular mechanisms involved in macrophage survival, proliferation, activation or apoptosis
    • Xaus J, Comalada M, Valledor AF, et al. Molecular mechanisms involved in macrophage survival, proliferation, activation or apoptosis. Immunobiology. 2001;204(5):543-550.
    • (2001) Immunobiology , vol.204 , Issue.5 , pp. 543-550
    • Xaus, J.1    Comalada, M.2    Valledor, A.F.3
  • 15
    • 0842346188 scopus 로고    scopus 로고
    • Regulation of myeloid development and function by colony stimulating factors
    • Barreda DR, Hanington PC, Belosevic M. Regulation of myeloid development and function by colony stimulating factors. Dev Comp Immunol. 2004;28(5):509-554.
    • (2004) Dev Comp Immunol , vol.28 , Issue.5 , pp. 509-554
    • Barreda, D.R.1    Hanington, P.C.2    Belosevic, M.3
  • 16
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: In vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest. 2012; 122(3):787-795.
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 17
    • 84905107360 scopus 로고    scopus 로고
    • Dendritic cells, monocytes and macrophages: A unified nomenclature based on ontogeny
    • Guilliams M, Ginhoux F, Jakubzick C, et al. Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol. 2014;14(8):571-578.
    • (2014) Nat Rev Immunol , vol.14 , Issue.8 , pp. 571-578
    • Guilliams, M.1    Ginhoux, F.2    Jakubzick, C.3
  • 18
    • 0344585940 scopus 로고    scopus 로고
    • The interacting pathways for prevention and repair of oxidative DNA damage
    • Slupphaug G, Kavli B, Krokan HE. The interacting pathways for prevention and repair of oxidative DNA damage. Mutat Res. 2003;531(1-2):231-251.
    • (2003) Mutat Res , vol.531 , Issue.1-2 , pp. 231-251
    • Slupphaug, G.1    Kavli, B.2    Krokan, H.E.3
  • 21
    • 0030057122 scopus 로고    scopus 로고
    • The transcription factor PU.1 is involved in macrophage proliferation
    • Celada A, Borràs FE, Soler C, et al. The transcription factor PU.1 is involved in macrophage proliferation. J Exp Med. 1996; 184(1):61-69.
    • (1996) J Exp Med , vol.184 , Issue.1 , pp. 61-69
    • Celada, A.1    Borràs, F.E.2    Soler, C.3
  • 22
    • 84890401989 scopus 로고    scopus 로고
    • The exonuclease Trex1 restrains macrophage proinflammatory activation
    • Pereira-Lopes S, Celhar T, Sans-Fons G, et al. The exonuclease Trex1 restrains macrophage proinflammatory activation. J Immunol. 2013; 191(12):6128-6135.
    • (2013) J Immunol , vol.191 , Issue.12 , pp. 6128-6135
    • Pereira-Lopes, S.1    Celhar, T.2    Sans-Fons, G.3
  • 23
    • 0033166302 scopus 로고    scopus 로고
    • Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
    • Xaus J, Cardó M, Valledor AF, Soler C, Lloberas J, Celada A. Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity. 1999;11(1):103-113.
    • (1999) Immunity , vol.11 , Issue.1 , pp. 103-113
    • Xaus, J.1    Cardó, M.2    Valledor, A.F.3    Soler, C.4    Lloberas, J.5    Celada, A.6
  • 24
    • 70149091119 scopus 로고    scopus 로고
    • Telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation
    • Sebastián C, Herrero C, Serra M, Lloberas J, Blasco MA, Celada A. Telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation. J Immunol. 2009;183(4):2356-2364.
    • (2009) J Immunol , vol.183 , Issue.4 , pp. 2356-2364
    • Sebastián, C.1    Herrero, C.2    Serra, M.3    Lloberas, J.4    Blasco, M.A.5    Celada, A.6
  • 25
    • 0020554955 scopus 로고
    • Polyamine starvation causes parallel increase in nuclear and chromosomal aberrations in a polyaminedependent strain of CHO
    • Knuutila S, Pohjanpelto P. Polyamine starvation causes parallel increase in nuclear and chromosomal aberrations in a polyaminedependent strain of CHO. Exp Cell Res. 1983; 145(1):222-226.
    • (1983) Exp Cell Res , vol.145 , Issue.1 , pp. 222-226
    • Knuutila, S.1    Pohjanpelto, P.2
  • 26
    • 65749109755 scopus 로고    scopus 로고
    • Chapter 17. Zymosan-induced peritonitis as a simple experimental system for the study of inflammation
    • Cash JL, White GE, Greaves DR. Chapter 17. Zymosan-induced peritonitis as a simple experimental system for the study of inflammation. Methods Enzymol. 2009;461:379-396.
    • (2009) Methods Enzymol , vol.461 , pp. 379-396
    • Cash, J.L.1    White, G.E.2    Greaves, D.R.3
  • 27
    • 34248546719 scopus 로고    scopus 로고
    • Skin contact irritation conditions the development and severity of allergic contact dermatitis
    • Bonneville M, Chavagnac C, Vocanson M, et al. Skin contact irritation conditions the development and severity of allergic contact dermatitis. J Invest Dermatol. 2007;127(6):1430-1435.
    • (2007) J Invest Dermatol , vol.127 , Issue.6 , pp. 1430-1435
    • Bonneville, M.1    Chavagnac, C.2    Vocanson, M.3
  • 28
    • 4444322816 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor-, granulocyte-macrophage colony-stimulating factor-, or IL-3-dependent survival of macrophages, but not proliferation, requires the expression of p21(Waf1) through the phosphatidylinositol 3-kinase/Akt pathway
    • Comalada M, Xaus J, Sánchez E, Valledor AF, Celada A. Macrophage colony-stimulating factor-, granulocyte-macrophage colony-stimulating factor-, or IL-3-dependent survival of macrophages, but not proliferation, requires the expression of p21(Waf1) through the phosphatidylinositol 3-kinase/Akt pathway. Eur J Immunol. 2004;34(8):2257-2267.
    • (2004) Eur J Immunol , vol.34 , Issue.8 , pp. 2257-2267
    • Comalada, M.1    Xaus, J.2    Sánchez, E.3    Valledor, A.F.4    Celada, A.5
  • 29
    • 0026731894 scopus 로고
    • Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
    • Collins MK, Marvel J, Malde P, Lopez-Rivas A. Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents. J Exp Med. 1992;176(4):1043-1051.
    • (1992) J Exp Med , vol.176 , Issue.4 , pp. 1043-1051
    • Collins, M.K.1    Marvel, J.2    Malde, P.3    Lopez-Rivas, A.4
  • 30
    • 33646467053 scopus 로고    scopus 로고
    • Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages
    • Yeramian A, Martin L, Serrat N, et al. Arginine transport via cationic amino acid transporter 2 plays a critical regulatory role in classical or alternative activation of macrophages. J Immunol. 2006;176(10):5918-5924.
    • (2006) J Immunol , vol.176 , Issue.10 , pp. 5918-5924
    • Yeramian, A.1    Martin, L.2    Serrat, N.3
  • 31
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol. 2001;1(2):135-145.
    • (2001) Nat Rev Immunol , vol.1 , Issue.2 , pp. 135-145
    • Medzhitov, R.1
  • 32
    • 0034892653 scopus 로고    scopus 로고
    • Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication
    • Costanzo V, Robertson K, Bibikova M, et al. Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication. Mol Cell. 2001;8(1):137-147.
    • (2001) Mol Cell , vol.8 , Issue.1 , pp. 137-147
    • Costanzo, V.1    Robertson, K.2    Bibikova, M.3
  • 33
    • 1642270611 scopus 로고    scopus 로고
    • Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/ Chk2
    • RogoffHA, Pickering MT, Frame FM, et al. Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/ Chk2. Mol Cell Biol. 2004;24(7):2968-2977.
    • (2004) Mol Cell Biol , vol.24 , Issue.7 , pp. 2968-2977
    • Rogoff, H.A.1    Pickering, M.T.2    Frame, F.M.3
  • 34
    • 84929513000 scopus 로고    scopus 로고
    • DNA damage checkpoint recovery and cancer development
    • Wang H, Zhang X, Teng L, Legerski RJ. DNA damage checkpoint recovery and cancer development. Exp Cell Res. 2015;334(2):350-358.
    • (2015) Exp Cell Res , vol.334 , Issue.2 , pp. 350-358
    • Wang, H.1    Zhang, X.2    Teng, L.3    Legerski, R.J.4
  • 35
    • 46149124528 scopus 로고    scopus 로고
    • Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage
    • Stracker TH, Couto SS, Cordon-Cardo C, Matos T, Petrini JH. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Mol Cell. 2008;31(1):21-32.
    • (2008) Mol Cell , vol.31 , Issue.1 , pp. 21-32
    • Stracker, T.H.1    Couto, S.S.2    Cordon-Cardo, C.3    Matos, T.4    Petrini, J.H.5
  • 36
    • 58849135489 scopus 로고    scopus 로고
    • Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS
    • Shull ER, Lee Y, Nakane H, et al. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS. Genes Dev. 2009;23(2):171-180.
    • (2009) Genes Dev , vol.23 , Issue.2 , pp. 171-180
    • Shull, E.R.1    Lee, Y.2    Nakane, H.3
  • 38
    • 84865433349 scopus 로고    scopus 로고
    • DNA damage checkpoints in stem cells, ageing and cancer
    • Sperka T, Wang J, Rudolph KL. DNA damage checkpoints in stem cells, ageing and cancer. Nat Rev Mol Cell Biol. 2012;13(9):579-590.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.9 , pp. 579-590
    • Sperka, T.1    Wang, J.2    Rudolph, K.L.3
  • 39
    • 0035116898 scopus 로고    scopus 로고
    • IFNgamma-dependent transcription of MHC class II IA is impaired in macrophages from aged mice
    • Herrero C, Marqués L, Lloberas J, Celada A. IFNgamma-dependent transcription of MHC class II IA is impaired in macrophages from aged mice. J Clin Invest. 2001;107(4):485-493.
    • (2001) J Clin Invest , vol.107 , Issue.4 , pp. 485-493
    • Herrero, C.1    Marqués, L.2    Lloberas, J.3    Celada, A.4
  • 40
    • 79960464308 scopus 로고    scopus 로고
    • Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-kB signaling in resident macrophages
    • Choi H, Lee RH, Bazhanov N, Oh JY, Prockop DJ. Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-kB signaling in resident macrophages. Blood. 2011; 118(2):330-338.
    • (2011) Blood , vol.118 , Issue.2 , pp. 330-338
    • Choi, H.1    Lee, R.H.2    Bazhanov, N.3    Oh, J.Y.4    Prockop, D.J.5
  • 41
    • 84878738380 scopus 로고    scopus 로고
    • Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation
    • 1886
    • Davies LC, Rosas M, Jenkins SJ, et al. Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation. Nat Commun. 2013;4:1886.
    • (2013) Nat Commun , vol.4
    • Davies, L.C.1    Rosas, M.2    Jenkins, S.J.3
  • 42
    • 0034782946 scopus 로고    scopus 로고
    • Redox signaling in macrophages
    • Forman HJ, Torres M. Redox signaling in macrophages. Mol Aspects Med. 2001;22(4-5):189-216.
    • (2001) Mol Aspects Med , vol.22 , Issue.4-5 , pp. 189-216
    • Forman, H.J.1    Torres, M.2
  • 43
    • 84867452253 scopus 로고    scopus 로고
    • Pathways for repairing and tolerating the spectrum of oxidative DNA lesions
    • Berquist BR, Wilson DM III. Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett. 2012;327(1-2):61-72.
    • (2012) Cancer Lett , vol.327 , Issue.1-2 , pp. 61-72
    • Berquist, B.R.1    Wilson, D.M.2
  • 44
    • 30344449735 scopus 로고    scopus 로고
    • Respiratory burst: Role in signal transduction in alveolar macrophages
    • Gwinn MR, Vallyathan V. Respiratory burst: role in signal transduction in alveolar macrophages. J Toxicol Environ Health B Crit Rev. 2006;9(1):27-39.
    • (2006) J Toxicol Environ Health B Crit Rev , vol.9 , Issue.1 , pp. 27-39
    • Gwinn, M.R.1    Vallyathan, V.2
  • 45
    • 68949149732 scopus 로고    scopus 로고
    • Multiple roles for MRE11 at uncapped telomeres
    • Deng Y, Guo X, Ferguson DO, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature. 2009;460(7257):914-918.
    • (2009) Nature , vol.460 , Issue.7257 , pp. 914-918
    • Deng, Y.1    Guo, X.2    Ferguson, D.O.3    Chang, S.4
  • 46
    • 84855490596 scopus 로고    scopus 로고
    • Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress
    • Bauer M, Goldstein M, Christmann M, Becker H, Heylmann D, Kaina B. Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress. Proc Natl Acad Sci USA. 2011; 108(52):21105-21110.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.52 , pp. 21105-21110
    • Bauer, M.1    Goldstein, M.2    Christmann, M.3    Becker, H.4    Heylmann, D.5    Kaina, B.6
  • 47
    • 68249096784 scopus 로고    scopus 로고
    • Persistent DNA damage signalling triggers senescenceassociated inflammatory cytokine secretion
    • Rodier F, Coppé JP, Patil CK, et al. Persistent DNA damage signalling triggers senescenceassociated inflammatory cytokine secretion. Nat Cell Biol. 2009;11(8):973-979.
    • (2009) Nat Cell Biol , vol.11 , Issue.8 , pp. 973-979
    • Rodier, F.1    Coppé, J.P.2    Patil, C.K.3
  • 48
    • 84926523961 scopus 로고    scopus 로고
    • Senescence-associated inflammatory responses: Aging and cancer perspectives
    • Lasry A, Ben-Neriah Y. Senescence-associated inflammatory responses: aging and cancer perspectives. Trends Immunol. 2015;36(4):217-228.
    • (2015) Trends Immunol , vol.36 , Issue.4 , pp. 217-228
    • Lasry, A.1    Ben-Neriah, Y.2
  • 49
    • 84901038448 scopus 로고    scopus 로고
    • Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1b production
    • Roth S, Rottach A, Lotz-Havla AS, et al. Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1b production. Nat Immunol. 2014;15(6):538-545.
    • (2014) Nat Immunol , vol.15 , Issue.6 , pp. 538-545
    • Roth, S.1    Rottach, A.2    Lotz-Havla, A.S.3
  • 50
    • 84874278336 scopus 로고    scopus 로고
    • DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type i interferon by regulating STING trafficking
    • Kondo T, Kobayashi J, Saitoh T, et al. DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking. Proc Natl Acad Sci USA. 2013;110(8):2969-2974.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.8 , pp. 2969-2974
    • Kondo, T.1    Kobayashi, J.2    Saitoh, T.3
  • 51
    • 84922986861 scopus 로고    scopus 로고
    • DNA damage primes the type i interferon system via the cytosolic DNA sensor STING to promote antimicrobial innate immunity
    • Härtlova A, Erttmann SF, RaffiFA, et al. DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote antimicrobial innate immunity. Immunity. 2015;42(2):332-343.
    • (2015) Immunity , vol.42 , Issue.2 , pp. 332-343
    • Härtlova, A.1    Erttmann, S.F.2    Raffi, F.A.3
  • 52
    • 84925501444 scopus 로고    scopus 로고
    • Human disease phenotypes associated with mutations in TREX1
    • Rice GI, Rodero MP, Crow YJ. Human disease phenotypes associated with mutations in TREX1. J Clin Immunol. 2015;35(3):235-243.
    • (2015) J Clin Immunol , vol.35 , Issue.3 , pp. 235-243
    • Rice, G.I.1    Rodero, M.P.2    Crow, Y.J.3
  • 53
    • 36248988008 scopus 로고    scopus 로고
    • Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
    • Yang YG, Lindahl T, Barnes DE. Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease. Cell. 2007;131(5):873-886.
    • (2007) Cell , vol.131 , Issue.5 , pp. 873-886
    • Yang, Y.G.1    Lindahl, T.2    Barnes, D.E.3
  • 54
    • 84927582093 scopus 로고    scopus 로고
    • Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFNstimulated gene response and cytokine release
    • Cuadrado E, Michailidou I, van Bodegraven EJ, et al. Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFNstimulated gene response and cytokine release. J Immunol. 2015;194(8):3623-3633.
    • (2015) J Immunol , vol.194 , Issue.8 , pp. 3623-3633
    • Cuadrado, E.1    Michailidou, I.2    Van Bodegraven, E.J.3
  • 55
    • 84933279572 scopus 로고    scopus 로고
    • Aicardi-Goutières syndrome and the type i interferonopathies
    • Crow YJ, Manel N. Aicardi-Goutières syndrome and the type I interferonopathies. Nat Rev Immunol. 2015;15(7):429-440.
    • (2015) Nat Rev Immunol , vol.15 , Issue.7 , pp. 429-440
    • Crow, Y.J.1    Manel, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.