Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release

Journal of Immunology

Volumn 194, Issue 8, 2015, Pages 3623-3633

  Cuadrado, Eloy ^a,b   Michailidou, Iliana ^c   Van Bodegraven, Emma J ^d   Jansen, Machiel H ^b   Sluijs, Jacqueline A ^a,d   Geerts, Dirk ^e   Couraud, Pierre Olivier ^f   Filippis, Lidia De ^g   Vescovi, Angelo L ^g   Kuijpers, Taco W ^b   Hol, Elly M ^a,d,h  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f CNRS   (France)

^g UNIVERSITY OF MILANO BICOCCA   (Italy)

^h UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HLA C ANTIGEN; INTERLEUKIN 6; RANTES; SHORT HAIRPIN RNA; ADAR1 PROTEIN, HUMAN; ADENOSINE DEAMINASE; CYTOKINE; EXODEOXYRIBONUCLEASE; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHOPROTEIN; RIBONUCLEASE H; RIBONUCLEASE HII; RNA BINDING PROTEIN; SAMHD1 PROTEIN, HUMAN; THREE PRIME REPAIR EXONUCLEASE 1;

ADAR1 GENE; AICARDI GOUTIERES SYNDROME; APOPTOSIS; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; ENDOTHELIUM CELL; GENE; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; PATHOGENESIS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RNASEH2A GENE; SAMHD1 GENE; TREX1 GENE; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; MORTALITY; MUTATION; NERVOUS SYSTEM MALFORMATION; NEURAL STEM CELL; NEUROLOGIC DISEASE; PATHOLOGY;

ADENOSINE DEAMINASE; ASTROCYTES; AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM; CYTOKINES; ENDOTHELIAL CELLS; EXODEOXYRIBONUCLEASES; GENE SILENCING; HEK293 CELLS; HUMANS; INTERFERON-ALPHA; MONOMERIC GTP-BINDING PROTEINS; MUTATION; NERVOUS SYSTEM MALFORMATIONS; NEURAL STEM CELLS; PHOSPHOPROTEINS; RIBONUCLEASE H; RNA-BINDING PROTEINS;

EID: 84927582093     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401334     Document Type: Article

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