Clostridium perfringens epsilon toxin binds to membrane lipids and its cytotoxic action depends on sulfatide

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Gil, Carles ^a   Dorca Arévalo, Jonatan ^b,c   Blasi, Juan ^b,c  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CHOLESTEROL; EPSILON TOXIN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLINOSITOL 5 PHOSPHATE; PHOSPHATIDYLSERINE; SPHINGOLIPID; SULFATIDE; UNCLASSIFIED DRUG; CLOSTRIDIUM PERFRINGENS EPSILON-TOXIN; CYTOTOXIN; DETERGENT; SULFATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; BRAIN SYNAPTOSOME; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; CYTOTOXICITY; LIPID MEMBRANE; LIPID RAFT; NONHUMAN; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PROTEIN LIPID INTERACTION; RAT; SCHWANN CELL; ANIMAL; CELL MEMBRANE; CHEMISTRY; DOG; DRUG EFFECTS; MDCK CELL LINE; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; BACTERIAL TOXINS; CELL MEMBRANE; CYTOTOXINS; DETERGENTS; DOGS; MADIN DARBY CANINE KIDNEY CELLS; PHOSPHATIDYLINOSITOLS; PHOSPHATIDYLSERINES; RATS; RATS, SPRAGUE-DAWLEY; SULFATES; SULFOGLYCOSPHINGOLIPIDS;

EID: 84948650513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140321     Document Type: Article

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