The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Rumah, Kareem Rashid ^a,b   Ma, Yinghua ^a   Linden, Jennifer R ^a   Oo, Myat Lin ^a   Anrather, Josef ^a   Schaeren Wiemers, Nicole ^c   Alonso, Miguel A ^d   Fischetti, Vincent A ^b   McClain, Mark S ^e   Vartanian, Timothy ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF BASEL   (Switzerland)

^d CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CLOSTRIDIUM PERFRINGENS EPSILON TOXIN; MYELIN AND LYMPHOCYTE PROTEIN; UNCLASSIFIED DRUG; CLOSTRIDIUM PERFRINGENS EPSILON-TOXIN; HYBRID PROTEIN; LIGAND; MAL PROTEIN, HUMAN; MAL PROTEIN, RAT; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; WESTERN BLOTTING; ANIMAL; BINDING SITE; C57BL MOUSE; CELL DEATH; CHEMISTRY; CHO CELL LINE; CLOSTRIDIUM PERFRINGENS; COMPARATIVE STUDY; CRICETULUS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; PATHOGENICITY; PROTEIN DOMAIN; RAT; TISSUE DISTRIBUTION; TOXICOKINETICS;

ANIMALIA; CLOSTRIDIUM PERFRINGENS; CRICETULUS GRISEUS; MAMMALIA; MUS; RATTUS;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CELL DEATH; CHO CELLS; CLOSTRIDIUM PERFRINGENS; CRICETULUS; HUMANS; INJECTIONS, INTRAVENOUS; LIGANDS; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS, INSERTIONAL; MYELIN AND LYMPHOCYTE-ASSOCIATED PROTEOLIPID PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PRECURSORS; RATS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION; TOXICOKINETICS;

EID: 84930329709     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004896     Document Type: Article

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