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Volumn 89, Issue 6, 2013, Pages 1154-1166

Mycobacterium tuberculosisEspB binds phospholipids and mediates EsxA-independent virulence

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; ESCHERICHIA COLI SECRETED PROTEIN A; INTERLEUKIN 1BETA; MESSENGER RNA; PHOSPHATIDIC ACID; PHOSPHATIDYLSERINE; PROTEIN ESPB; PROTEIN ESPC; PROTEIN ESPD; UNCLASSIFIED DRUG; PHOSPHOLIPID; PROTEIN BINDING; VIRULENCE FACTOR;

EID: 84884285987     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12336     Document Type: Article
Times cited : (66)

References (53)
  • 1
    • 0345621667 scopus 로고    scopus 로고
    • Survival of mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis
    • Bange, F.C., Collins, F.M., and Jacobs, W.R., Jr (1999) Survival of mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis. Tuber Lung Dis 79: 171-180.
    • (1999) Tuber Lung Dis , vol.79 , pp. 171-180
    • Bange, F.C.1    Collins, F.M.2    Jacobs Jr., W.R.3
  • 2
    • 84861210509 scopus 로고    scopus 로고
    • Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein
    • Blasco, B., Chen, J.M., Hartkoorn, R., Sala, C., Uplekar, S., Rougemont, J., etal. (2012) Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein. PLoS Pathog 8: e1002621.
    • (2012) PLoS Pathog , vol.8
    • Blasco, B.1    Chen, J.M.2    Hartkoorn, R.3    Sala, C.4    Uplekar, S.5    Rougemont, J.6
  • 3
    • 84872352440 scopus 로고    scopus 로고
    • Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis
    • Bohdanowicz, M., and Grinstein, S. (2013) Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis. Physiol Rev 93: 69-106.
    • (2013) Physiol Rev , vol.93 , pp. 69-106
    • Bohdanowicz, M.1    Grinstein, S.2
  • 4
    • 26644466308 scopus 로고    scopus 로고
    • Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity
    • Brodin, P., de Jonge, M.I., Majlessi, L., Leclerc, C., Nilges, M., Cole, S.T., and Brosch, R. (2005) Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity. J Biol Chem 280: 33953-33959.
    • (2005) J Biol Chem , vol.280 , pp. 33953-33959
    • Brodin, P.1    de Jonge, M.I.2    Majlessi, L.3    Leclerc, C.4    Nilges, M.5    Cole, S.T.6    Brosch, R.7
  • 5
    • 29644438456 scopus 로고    scopus 로고
    • Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence
    • Brodin, P., Majlessi, L., Marsollier, L., de Jonge, M.I., Bottai, D., Demangel, C., etal. (2006) Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infect Immun 74: 88-98.
    • (2006) Infect Immun , vol.74 , pp. 88-98
    • Brodin, P.1    Majlessi, L.2    Marsollier, L.3    de Jonge, M.I.4    Bottai, D.5    Demangel, C.6
  • 6
    • 84863116545 scopus 로고    scopus 로고
    • EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis
    • Chen, J.M., Boy-Rottger, S., Dhar, N., Sweeney, N., Buxton, R.S., Pojer, F., etal. (2012) EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis. J Bacteriol 194: 884-893.
    • (2012) J Bacteriol , vol.194 , pp. 884-893
    • Chen, J.M.1    Boy-Rottger, S.2    Dhar, N.3    Sweeney, N.4    Buxton, R.S.5    Pojer, F.6
  • 8
    • 84871752747 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis
    • De Leon, J., Jiang, G., Ma, Y., Rubin, E., Fortune, S., and Sun, J. (2012) Mycobacterium tuberculosis ESAT-6 exhibits a unique membrane-interacting activity that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis. J Biol Chem 287: 44184-44191.
    • (2012) J Biol Chem , vol.287 , pp. 44184-44191
    • De Leon, J.1    Jiang, G.2    Ma, Y.3    Rubin, E.4    Fortune, S.5    Sun, J.6
  • 9
    • 70350156606 scopus 로고    scopus 로고
    • ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria
    • DiGiuseppe Champion, P.A., Champion, M.M., Manzanillo, P., and Cox, J.S. (2009) ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria. Mol Microbiol 73: 950-962.
    • (2009) Mol Microbiol , vol.73 , pp. 950-962
    • DiGiuseppe Champion, P.A.1    Champion, M.M.2    Manzanillo, P.3    Cox, J.S.4
  • 10
    • 24044538903 scopus 로고    scopus 로고
    • IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content
    • Dosztanyi, Z., Csizmok, V., Tompa, P., and Simon, I. (2005) IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics 21: 3433-3434.
    • (2005) Bioinformatics , vol.21 , pp. 3433-3434
    • Dosztanyi, Z.1    Csizmok, V.2    Tompa, P.3    Simon, I.4
  • 11
    • 58249100330 scopus 로고    scopus 로고
    • Intracellular replication of attenuated Mycobacterium tuberculosis phoP mutant in the absence of host cell cytotoxicity
    • Ferrer, N.L., Gomez, A.B., Soto, C.Y., Neyrolles, O., Gicquel, B., Garcia-Del Portillo, F., and Martin, C. (2009) Intracellular replication of attenuated Mycobacterium tuberculosis phoP mutant in the absence of host cell cytotoxicity. Microbes Infect 11: 115-122.
    • (2009) Microbes Infect , vol.11 , pp. 115-122
    • Ferrer, N.L.1    Gomez, A.B.2    Soto, C.Y.3    Neyrolles, O.4    Gicquel, B.5    Garcia-Del Portillo, F.6    Martin, C.7
  • 13
    • 77954668186 scopus 로고    scopus 로고
    • EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity
    • Garces, A., Atmakuri, K., Chase, M.R., Woodworth, J.S., Krastins, B., Rothchild, A.C., etal. (2010) EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog 6: e1000957.
    • (2010) PLoS Pathog , vol.6
    • Garces, A.1    Atmakuri, K.2    Chase, M.R.3    Woodworth, J.S.4    Krastins, B.5    Rothchild, A.C.6
  • 14
    • 71649089075 scopus 로고    scopus 로고
    • Natural lysophospholipids reduce Mycobacterium tuberculosis-induced cytotoxicity and induce anti-mycobacterial activity by a phagolysosome maturation-dependent mechanism in A549 type II alveolar epithelial cells
    • Greco, E., Santucci, M.B., Sali, M., De Angelis, F.R., Papi, M., De Spirito, M., etal. (2010) Natural lysophospholipids reduce Mycobacterium tuberculosis-induced cytotoxicity and induce anti-mycobacterial activity by a phagolysosome maturation-dependent mechanism in A549 type II alveolar epithelial cells. Immunology 129: 125-132.
    • (2010) Immunology , vol.129 , pp. 125-132
    • Greco, E.1    Santucci, M.B.2    Sali, M.3    De Angelis, F.R.4    Papi, M.5    De Spirito, M.6
  • 15
    • 0942290453 scopus 로고    scopus 로고
    • Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis
    • Guinn, K.M., Hickey, M.J., Mathur, S.K., Zakel, K.L., Grotzke, J.E., Lewinsohn, D.M., etal. (2004) Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis. Mol Microbiol 51: 359-370.
    • (2004) Mol Microbiol , vol.51 , pp. 359-370
    • Guinn, K.M.1    Hickey, M.J.2    Mathur, S.K.3    Zakel, K.L.4    Grotzke, J.E.5    Lewinsohn, D.M.6
  • 16
    • 80051798347 scopus 로고    scopus 로고
    • Manipulation of host membranes by bacterial effectors
    • Ham, H., Sreelatha, A., and Orth, K. (2011) Manipulation of host membranes by bacterial effectors. Nat Rev Microbiol 9: 635-646.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 635-646
    • Ham, H.1    Sreelatha, A.2    Orth, K.3
  • 17
    • 84872005854 scopus 로고    scopus 로고
    • Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA
    • Hayashi, T., Senda, M., Morohashi, H., Higashi, H., Horio, M., Kashiba, Y., etal. (2012) Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA. Cell Host Microbe 12: 20-33.
    • (2012) Cell Host Microbe , vol.12 , pp. 20-33
    • Hayashi, T.1    Senda, M.2    Morohashi, H.3    Higashi, H.4    Horio, M.5    Kashiba, Y.6
  • 18
    • 33749563813 scopus 로고    scopus 로고
    • Modulation of phosphoinositide metabolism by pathogenic bacteria
    • Hilbi, H. (2006) Modulation of phosphoinositide metabolism by pathogenic bacteria. Cell Microbiol 8: 1697-1706.
    • (2006) Cell Microbiol , vol.8 , pp. 1697-1706
    • Hilbi, H.1
  • 19
    • 84865154655 scopus 로고    scopus 로고
    • Secretive bacterial pathogens and the secretory pathway
    • Hilbi, H., and Haas, A. (2012) Secretive bacterial pathogens and the secretory pathway. Traffic 13: 1187-1197.
    • (2012) Traffic , vol.13 , pp. 1187-1197
    • Hilbi, H.1    Haas, A.2
  • 20
    • 82355174106 scopus 로고    scopus 로고
    • Anchors for effectors: subversion of phosphoinositide lipids by legionella
    • Hilbi, H., Weber, S., and Finsel, I. (2011) Anchors for effectors: subversion of phosphoinositide lipids by legionella. Front Microbiol 2: 1-8.
    • (2011) Front Microbiol , vol.2 , pp. 1-8
    • Hilbi, H.1    Weber, S.2    Finsel, I.3
  • 21
    • 46549085541 scopus 로고    scopus 로고
    • A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures
    • Ivanova, L., and Uhlig, S. (2008) A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures. Anal Biochem 379: 16-19.
    • (2008) Anal Biochem , vol.379 , pp. 16-19
    • Ivanova, L.1    Uhlig, S.2
  • 22
    • 34547766513 scopus 로고    scopus 로고
    • ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
    • de Jonge, M.I., Pehau-Arnaudet, G., Fretz, M.M., Romain, F., Bottai, D., Brodin, P., etal. (2007) ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. J Bacteriol 189: 6028-6034.
    • (2007) J Bacteriol , vol.189 , pp. 6028-6034
    • de Jonge, M.I.1    Pehau-Arnaudet, G.2    Fretz, M.M.3    Romain, F.4    Bottai, D.5    Brodin, P.6
  • 23
    • 80655149460 scopus 로고    scopus 로고
    • Functional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands
    • Krachler, A.M., and Orth, K. (2011) Functional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands. J Biol Chem 286: 38939-38947.
    • (2011) J Biol Chem , vol.286 , pp. 38939-38947
    • Krachler, A.M.1    Orth, K.2
  • 24
    • 79961010783 scopus 로고    scopus 로고
    • Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens
    • Krachler, A.M., Ham, H., and Orth, K. (2011a) Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens. Proc Natl Acad Sci USA 108: 11614-11619.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 11614-11619
    • Krachler, A.M.1    Ham, H.2    Orth, K.3
  • 25
    • 84856785397 scopus 로고    scopus 로고
    • Manipulation of kinase signaling by bacterial pathogens
    • Krachler, A.M., Woolery, A.R., and Orth, K. (2011b) Manipulation of kinase signaling by bacterial pathogens. J Cell Biol 195: 1083-1092.
    • (2011) J Cell Biol , vol.195 , pp. 1083-1092
    • Krachler, A.M.1    Woolery, A.R.2    Orth, K.3
  • 26
    • 0033957426 scopus 로고    scopus 로고
    • ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D
    • Kusner, D.J., and Adams, J. (2000) ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J Immunol 164: 379-388.
    • (2000) J Immunol , vol.164 , pp. 379-388
    • Kusner, D.J.1    Adams, J.2
  • 28
    • 0037219942 scopus 로고    scopus 로고
    • Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation
    • Lewis, K.N., Liao, R., Guinn, K.M., Hickey, M.J., Smith, S., Behr, M.A., and Sherman, D.R. (2003) Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation. J Infect Dis 187: 117-123.
    • (2003) J Infect Dis , vol.187 , pp. 117-123
    • Lewis, K.N.1    Liao, R.2    Guinn, K.M.3    Hickey, M.J.4    Smith, S.5    Behr, M.A.6    Sherman, D.R.7
  • 29
    • 25144441735 scopus 로고    scopus 로고
    • A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis
    • MacGurn, J.A., Raghavan, S., Stanley, S.A., and Cox, J.S. (2005) A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis. Mol Microbiol 57: 1653-1663.
    • (2005) Mol Microbiol , vol.57 , pp. 1653-1663
    • MacGurn, J.A.1    Raghavan, S.2    Stanley, S.A.3    Cox, J.S.4
  • 32
    • 79955044495 scopus 로고    scopus 로고
    • Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection
    • Millington, K.A., Fortune, S.M., Low, J., Garces, A., Hingley-Wilson, S.M., Wickremasinghe, M., etal. (2011) Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 108: 5730-5735.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 5730-5735
    • Millington, K.A.1    Fortune, S.M.2    Low, J.3    Garces, A.4    Hingley-Wilson, S.M.5    Wickremasinghe, M.6
  • 34
    • 77955292149 scopus 로고    scopus 로고
    • Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein
    • Murata-Kamiya, N., Kikuchi, K., Hayashi, T., Higashi, H., and Hatakeyama, M. (2010) Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein. Cell Host Microbe 7: 399-411.
    • (2010) Cell Host Microbe , vol.7 , pp. 399-411
    • Murata-Kamiya, N.1    Kikuchi, K.2    Hayashi, T.3    Higashi, H.4    Hatakeyama, M.5
  • 35
    • 0033003283 scopus 로고    scopus 로고
    • Vaccinated mice remain more susceptible to Mycobacterium tuberculosis infection initiated via the respiratory route than via the intravenous route
    • North, R.J., LaCourse, R., and Ryan, L. (1999) Vaccinated mice remain more susceptible to Mycobacterium tuberculosis infection initiated via the respiratory route than via the intravenous route. Infect Immun 67: 2010-2012.
    • (1999) Infect Immun , vol.67 , pp. 2010-2012
    • North, R.J.1    LaCourse, R.2    Ryan, L.3
  • 36
    • 77749336398 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence
    • Ohol, Y.M., Goetz, D.H., Chan, K., Shiloh, M.U., Craik, C.S., and Cox, J.S. (2010) Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence. Cell Host Microbe 7: 210-220.
    • (2010) Cell Host Microbe , vol.7 , pp. 210-220
    • Ohol, Y.M.1    Goetz, D.H.2    Chan, K.3    Shiloh, M.U.4    Craik, C.S.5    Cox, J.S.6
  • 37
    • 84868093284 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis modulators of the macrophage's cellular events
    • Poirier, V., and Av-Gay, Y. (2012) Mycobacterium tuberculosis modulators of the macrophage's cellular events. Microbes Infect 14: 1211-1219.
    • (2012) Microbes Infect , vol.14 , pp. 1211-1219
    • Poirier, V.1    Av-Gay, Y.2
  • 38
    • 0036437048 scopus 로고    scopus 로고
    • Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti
    • Pym, A.S., Brodin, P., Brosch, R., Huerre, M., and Cole, S.T. (2002) Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Mol Microbiol 46: 709-717.
    • (2002) Mol Microbiol , vol.46 , pp. 709-717
    • Pym, A.S.1    Brodin, P.2    Brosch, R.3    Huerre, M.4    Cole, S.T.5
  • 39
    • 0037077299 scopus 로고    scopus 로고
    • Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence
    • Renshaw, P.S., Panagiotidou, P., Whelan, A., Gordon, S.V., Hewinson, R.G., Williamson, R.A., and Carr, M.D. (2002) Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence. J Biol Chem 277: 21598-21603.
    • (2002) J Biol Chem , vol.277 , pp. 21598-21603
    • Renshaw, P.S.1    Panagiotidou, P.2    Whelan, A.3    Gordon, S.V.4    Hewinson, R.G.5    Williamson, R.A.6    Carr, M.D.7
  • 40
    • 84867648270 scopus 로고    scopus 로고
    • Subversion of phagocytosis for pathogen survival
    • Sarantis, H., and Grinstein, S. (2012) Subversion of phagocytosis for pathogen survival. Cell Host Microbe 12: 419-431.
    • (2012) Cell Host Microbe , vol.12 , pp. 419-431
    • Sarantis, H.1    Grinstein, S.2
  • 41
    • 3042803777 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis H37Rv: Delta RD1 is more virulent than M. bovis bacille Calmette-Guerin in long-term murine infection
    • Sherman, D.R., Guinn, K.M., Hickey, M.J., Mathur, S.K., Zakel, K.L., and Smith, S. (2004) Mycobacterium tuberculosis H37Rv: Delta RD1 is more virulent than M. bovis bacille Calmette-Guerin in long-term murine infection. J Infect Dis 190: 123-126.
    • (2004) J Infect Dis , vol.190 , pp. 123-126
    • Sherman, D.R.1    Guinn, K.M.2    Hickey, M.J.3    Mathur, S.K.4    Zakel, K.L.5    Smith, S.6
  • 42
    • 60049091769 scopus 로고    scopus 로고
    • ESX/type VII secretion systems and their role in host-pathogen interaction
    • Simeone, R., Bottai, D., and Brosch, R. (2009) ESX/type VII secretion systems and their role in host-pathogen interaction. Curr Opin Microbiol 12: 4-10.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 4-10
    • Simeone, R.1    Bottai, D.2    Brosch, R.3
  • 44
    • 57349164051 scopus 로고    scopus 로고
    • Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole
    • Smith, J., Manoranjan, J., Pan, M., Bohsali, A., Xu, J., Liu, J., etal. (2008) Evidence for pore formation in host cell membranes by ESX-1-secreted ESAT-6 and its role in Mycobacterium marinum escape from the vacuole. Infect Immun 76: 5478-5487.
    • (2008) Infect Immun , vol.76 , pp. 5478-5487
    • Smith, J.1    Manoranjan, J.2    Pan, M.3    Bohsali, A.4    Xu, J.5    Liu, J.6
  • 45
    • 33748300590 scopus 로고    scopus 로고
    • Phosphatidic acid- and phosphatidylserine-binding proteins
    • Stace, C.L., and Ktistakis, N.T. (2006) Phosphatidic acid- and phosphatidylserine-binding proteins. Biochim Biophys Acta 1761: 913-926.
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 913-926
    • Stace, C.L.1    Ktistakis, N.T.2
  • 46
    • 0242268398 scopus 로고    scopus 로고
    • Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system
    • Stanley, S.A., Raghavan, S., Hwang, W.W., and Cox, J.S. (2003) Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system. Proc Natl Acad Sci USA 100: 13001-13006.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13001-13006
    • Stanley, S.A.1    Raghavan, S.2    Hwang, W.W.3    Cox, J.S.4
  • 48
    • 84866951194 scopus 로고    scopus 로고
    • Tubercle bacilli rely on a type VII army for pathogenicity
    • Stoop, E.J., Bitter, W., and van der Sar, A.M. (2012) Tubercle bacilli rely on a type VII army for pathogenicity. Trends Microbiol 20: 477-484.
    • (2012) Trends Microbiol , vol.20 , pp. 477-484
    • Stoop, E.J.1    Bitter, W.2    van der Sar, A.M.3
  • 49
    • 0035991858 scopus 로고    scopus 로고
    • Simple fibroblast-based assay for screening of new antimicrobial drugs against Mycobacterium tuberculosis
    • Takii, T., Yamamoto, Y., Chiba, T., Abe, C., Belisle, J.T., Brennan, P.J., and Onozaki, K. (2002) Simple fibroblast-based assay for screening of new antimicrobial drugs against Mycobacterium tuberculosis. Antimicrob Agents Chemother 46: 2533-2539.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2533-2539
    • Takii, T.1    Yamamoto, Y.2    Chiba, T.3    Abe, C.4    Belisle, J.T.5    Brennan, P.J.6    Onozaki, K.7
  • 50
    • 34250716965 scopus 로고    scopus 로고
    • M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells
    • van der Wel, N., Hava, D., Houben, D., Fluitsma, D., van Zon, M., Pierson, J., etal. (2007) M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129: 1287-1298.
    • (2007) Cell , vol.129 , pp. 1287-1298
    • van der Wel, N.1    Hava, D.2    Houben, D.3    Fluitsma, D.4    van Zon, M.5    Pierson, J.6
  • 51
    • 80051810145 scopus 로고    scopus 로고
    • Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis
    • Wong, K.W., and Jacobs, W.R., Jr (2011) Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis. Cell Microbiol 13: 1371-1384.
    • (2011) Cell Microbiol , vol.13 , pp. 1371-1384
    • Wong, K.W.1    Jacobs Jr., W.R.2
  • 52
    • 20744437001 scopus 로고    scopus 로고
    • RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins
    • Yang, Z.R., Thomson, R., McNeil, P., and Esnouf, R.M. (2005) RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins. Bioinformatics 21: 3369-3376.
    • (2005) Bioinformatics , vol.21 , pp. 3369-3376
    • Yang, Z.R.1    Thomson, R.2    McNeil, P.3    Esnouf, R.M.4
  • 53
    • 66349091880 scopus 로고    scopus 로고
    • Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation
    • Yeung, T., Heit, B., Dubuisson, J.F., Fairn, G.D., Chiu, B., Inman, R., etal. (2009) Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol 185: 917-928.
    • (2009) J Cell Biol , vol.185 , pp. 917-928
    • Yeung, T.1    Heit, B.2    Dubuisson, J.F.3    Fairn, G.D.4    Chiu, B.5    Inman, R.6


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