Characterization of the high affinity binding of epsilon toxin from Clostridium perfringens to the renal system

Veterinary Microbiology

Volumn 157, Issue 1-2, 2012, Pages 179-189

  Dorca Arévalo, Jonatan ^a,b   Martín Satué, Mireia ^a,b   Blasi, Juan ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

Clostridium perfringens; Enterotoxaemia; Epsilon toxin; MDCK cell line; Pulpy kidney

Indexed keywords

BACTERIAL TOXIN; EPSILON TOXIN; GLYCOSIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL LINE; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MOUSE; NONHUMAN; TISSUE SECTION; UROGENITAL SYSTEM;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CELL DEATH; CELL LINE; CELL MEMBRANE; CLOSTRIDIUM PERFRINGENS; DETERGENTS; DOGS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GREEN FLUORESCENT PROTEINS; KIDNEY; KIDNEY TUBULES, COLLECTING; LECTINS; MICE; MICROSCOPY, CONFOCAL; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PRONASE; PROTEIN BINDING;

CLOSTRIDIUM PERFRINGENS; MAMMALIA; PUFFINUS AURICULARIS;

EID: 84859714573     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2011.12.020     Document Type: Article

References (29)

1. Buxton D. Use of horseradish peroxidase to study the antagonism of Clostridium welchii (C. perfringens) type D epsilon toxin in mice by the formalinized epsilon prototoxin. J. Comp. Pathol. 1976, 86:67-72.
2. Chassin C., Bens M., de Barry J., Courjaret R., Bossu J.L., Cluzeaud F., Ben Mkaddem S., Gibert M., Poulain B., Popoff M.R., Vandewalle A. Pore-forming epsilon toxin causes membrane permeabilization and rapid ATP depletion-mediated cell death in renal collecting duct cells. Am. J. Physiol. Renal Physiol. 2007, 293:F927-F937.
3. Desantis S., Ventriglia G., Zubani D., Deflorio M., Megalofonou P., Acone F., Zarrilli A., Palmieri G., De Metrio G. Histochemical analysis of glycoconjugates in the domestic cat testis. Histol. Histopathol. 2006, 21:11-22.
4. Dorca-Arevalo J., Soler-Jover A., Gibert M., Popoff M.R., Martin-Satue M., Blasi J. Binding of epsilon-toxin from Clostridium perfringens in the nervous system. Vet. Microbiol. 2008, 131:14-25.
5. Egea G., Goldstein I.J., Roth J. Light and electron microscopic detection of (3 Gal beta 1,4 GlcNAc beta 1) sequences in asparagine-linked oligosaccharides with the Datura stramonium lectin. Histochemistry 1989, 92:515-522.
6. Fernandez-Miyakawa M.E., Fisher D.J., Poon R., Sayeed S., Adams V., Rood J.I., McClane B.A., Uzal F.A. Both epsilon-toxin and beta-toxin are important for the lethal properties of Clostridium perfringens type B isolates in the mouse intravenous injection model. Infect. Immun. 2007, 75:1443-1452.
7. Fernandez-Miyakawa M.E., Jost B.H., Billington S.J., Uzal F.A. Lethal effects of Clostridium perfringens epsilon toxin are potentiated by alpha and perfringolysin-O toxins in a mouse model. Vet. Microbiol. 2008, 127:379-385.
8. Fernandez-Miyakawa M.E., Sayeed S., Fisher D.J., Poon R., Adams V., Rood J.I., McClane B.A., Saputo J., Uzal F.A. Development and application of an oral challenge mouse model for studying Clostridium perfringens type D infection. Infect. Immun. 2007, 75:4282-4288.
9. Finnie J.W. Histopathological changes in the brain of mice given Clostridium perfringens type D epsilon toxin. J. Comp. Pathol. 1984, 94:363-370.
10. Finnie J.W. Ultrastructural changes in the brain of mice given Clostridium perfringens type D epsilon toxin. J. Comp. Pathol. 1984, 94:445-452.
11. Hanai T., Usuda N., Morita T., Nagata T. Light microscopic lectin histochemistry in aging mouse kidney: study of compositional changes in glycoconjugates. J. Histochem. Cytochem. 1994, 42:897-906.
12. Ivie S.E., Fennessey C.M., Sheng J., Rubin D.H., McClain M.S. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens epsilon-toxin. PLoS One 2011, 6:e17787.
13. Koppelman M.C., Dufau M.L. Prolactin receptors in luteinized rat ovaries: unmasking of specific binding sites with detergent treatment. Endocrinology 1982, 111:1350-1357.
14. Laitinen L., Virtanen I., Saxen L. Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates. J. Histochem. Cytochem. 1987, 35:55-65.
15. Lindsay C.D. Assessment of aspects of the toxicity of Clostridium perfringens epsilon-toxin using the MDCK cell line. Hum. Exp. Toxicol. 1996, 15:904-908.
16. McCaslin D.R. Detergent properties. Encyclopedia Biol. Chem. 2004, 1:577-581.
17. Mello R.J., Brown M.S., Goldstein J.L., Anderson R.G. LDL receptors in coated vesicles isolated from bovine adrenal cortex: binding sites unmasked by detergent treatment. Cell 1980, 20:829-837.
18. Minami J., Katayama S., Matsushita O., Matsushita C., Okabe A. Lambda-toxin of Clostridium perfringens activates the precursor of epsilon-toxin by releasing its N- and C-terminal peptides. Microbiol. Immunol. 1997, 41:527-535.
19. Miyamoto O., Minami J., Toyoshima T., Nakamura T., Masada T., Nagao S., Negi T., Itano T., Okabe A. Neurotoxicity of Clostridium perfringens epsilon-toxin for the rat hippocampus via the glutamatergic system. Infect. Immun. 1998, 66:2501-2508.
20. Nagahama M., Sakurai J. High-affinity binding of Clostridium perfringens epsilon-toxin to rat brain. Infect. Immun. 1992, 60:1237-1240.
21. Payne D.W., Williamson E.D., Havard H., Modi N., Brown J. Evaluation of a new cytotoxicity assay for Clostridium perfringens type D epsilon toxin. FEMS Microbiol. Lett. 1994, 116:161-167.
22. Payne D.W., Oyston P.C. The Clostridium perfringens epsilon-toxin. The Clostridia. Molecular biology and pathogenesis 1997, 439-447. Academic Press, San Diego. J.I. Rood (Ed.).
23. Petit L., Gibert M., Gillet D., Laurent-Winter C., Boquet P., Popoff M.R. Clostridium perfringens epsilon-toxin acts on MDCK cells by forming a large membrane complex. J. Bacteriol. 1997, 179:6480-6487.
24. Pilch P.F., Shia M.A., Benson R.J., Fine R.E. Coated vesicles participate in the receptor-mediated endocytosis of insulin. J Cell Biol. 1983, 96:133-138.
25. Shimamoto S., Tamai E., Matsushita O., Minami J., Okabe A., Miyata S. Changes in ganglioside content affect the binding of Clostridium perfringens epsilon-toxin to detergent-resistant membranes of Madin-Darby canine kidney cells. Microbiol. Immunol. 2005, 49:245-253.
26. Soler-Jover A., Blasi J., Gomez de Aranda I., Navarro P., Gibert M., Popoff M.R., Martin-Satue M. Effect of epsilon toxin-GFP on MDCK cells and renal tubules in vivo. J. Histochem. Cytochem. 2004, 52:931-942.
27. Soler-Jover A., Dorca J., Popoff M.R., Gibert M., Saura J., Tusell J.M., Serratosa J., Blasi J., Martin-Satue M. Distribution of Clostridium perfringens epsilon toxin in the brains of acutely intoxicated mice and its effect upon glial cells. Toxicon 2007, 50:530-540.
28. Tamai E., Ishida T., Miyata S., Matsushita O., Suda H., Kobayashi S., Sonobe H., Okabe A. Accumulation of Clostridium perfringens epsilon-toxin in the mouse kidney and its possible biological significance. Infect. Immun. 2003, 71:5371-5375.
29. van der Goot F.G., Ausio J., Wong K.R., Pattus F., Buckley J.T. Dimerization stabilizes the pore-forming toxin aerolysin in solution. J. Biol. Chem. 1993, 268:18272-18279.