Neurological disorders produced by Clostridium perfringens type D epsilon toxin

Anaerobe

Volumn 10, Issue 2, 2004, Pages 145-150

  Finnie, John W ^a,b  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Clostridium perfringens type D; Epsilon toxin; Neuropathology; Pathogenesis

Indexed keywords

BACTERIAL TOXIN; TYPE D EPSILON TOXIN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL INJURY; BRAIN REGION; CLOSTRIDIUM PERFRINGENS; DEATH; DISEASE COURSE; DISEASE SEVERITY; EDEMA; ENCEPHALOMALACIA; ENDOTHELIUM INJURY; IMMUNITY; LAMB; LIVESTOCK; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL;

CLOSTRIDIUM; CLOSTRIDIUM PERFRINGENS; OVIS ARIES;

EID: 1942518454     PISSN: 10759964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anaerobe.2003.08.003     Document Type: Short Survey

References (55)

1. Barker I.K., Van Dreumel A.A., Palmer N. The alimentary system. Jubb K.V.F., Kennedy P.C., Palmer N. Pathology of domestic animals. 4th ed:1993;241-247 Academic Press, San Diego.
2. Songer J.G. Clostridial enteric diseases of domestic animals. Clin Microbiol Rev. 9:1996;216-234.
3. Payne D., Oyston P. The Clostridium perfringens epsilon toxin. Rood J.I., McClane B.A., Songer J.G., Titball R.W. The clostridia: molecular biology and pathogenesis. 1997;439-447 Academic Press, San Diego.
4. Finnie J.W. Pathogenesis of brain damage produced in sheep by Clostridium perfringens type D epsilon toxin. a review Aust Vet J. 81:2003;219-221.
5. Blackwell T.E., Butler D.G., Prescott J.F., Wilcock B.P. Differences in signs and lesions in sheep and goats with enterotoxaemia induced by intraduodenal infusion of Clostridium perfringens type D. Am J Vet Res. 52:1991;1147-1152.
6. Blackwell T.E., Butler D.G. Clinical signs, treatment and postmortem lesions in dairy goats with enterotoxaemia. 13 cases (1979-1982) J Am Vet Med Assoc. 200:1992;214-217.
7. Uzal F.A., Kelly W.R. Enterotoxaemia in goats. Vet Res Commun. 20:1996;481-492.
8. Uzal F.A., Glastonbury J.R., Kelly W.R., Thomas R. Caprine enterotoxaemia associated with cerebral microangiopathy. Vet Rec. 141:1997;224-226.
9. Buxton D., MacLeod N.S.M., Nicolson T.B. Focal symmetrical encephalomalacia in young cattle. Vet Rec. 108:1981;459.
10. Munday B.L., Mason B.W., Cumming R. Observations on diseases of the central nervous system of cattle in Tasmania. Aust Vet J. 49:1973;451-455.
11. Munday B.L., Mason B.W., Hartley W.J. Encephalopathies in cattle in Tasmania. Aust Vet J. 52:1976;92-96.
12. Radostits OM, Gay CC, Blood DC, Hinchcliff KW. Veterinary Medicine. 9th ed. London: WB Saunders; 2000. p. 773-7.
13. Stubbings D.P. Clostridium perfringens enterotoxaemia in 2 young horses. Vet Rec. 127:1990;431.
14. Percival D.A., Shuttleworth A.D., Williamson D.E., Kelly D.C. Anti-idiotypic antibody-induced protection against Clostridium perfringens type D. Infect Immun. 58:1990;2487-2492.
15. Worthington R.W., Mulders M.S.G., Van Rensburg J.J. Epsilon prototoxin. Some chemical, immunological and biological properties of a highly purified prototoxin. Onderstepoort J Vet Res. 40:1973;145-152.
16. Summers BA, Cummings JF, deLahunta A. Veterinary neuropathology. St. Louis: Mosby; 1995. p. 269-70.
17. Pienaar J.G., Thornton D.J. Focal symmetrical encephalomalacia in sheep in South Africa. J S Afr Vet Med Assoc. 35:1964;351-357.
18. Gardner D.E. Pathology of Clostridium welchii type D enterotoxaemia. III. Basis of the hyperglycaemic response. J Comp Pathol. 83:1973;525-529.
19. Gay C.C., Blood D.C., Wilkinson J.S. Clinical observations on sheep with focal symmetrical encephalomalacia. Aust Vet J. 51:1975;266-269.
20. Hartley W.J. A focal symmetrical encephalomalacia of lambs. NZ Vet J. 4:1956;129-135.
21. Garcia J.H., Anderson M.L. Circulatory disorders and their effects on the brain. Davis R.L., Robertson D.M. Textbook of neuropathology. 2nd ed:1991;659 Williams and Wilkins, Baltimore.
22. Courville C.B. Aetiology and pathogenesis of laminar cortical necrosis. Arch Neurol Psychiatr. 79:1958;7-30.
23. Griner L.A. Enterotoxaemia of sheep. I. Effects of Clostridium perfringens type D toxin on the brains of sheep and mice. Am J Vet Res. 22:1961;429-442.
24. Gould DH. The development of the early brain lesions induced by the toxin of Clostridium perfringens type D in mice and lambs. Ph.D. thesis, University of California Davis, 1972.
25. Gardner D.E. Pathology of Clostridium welchii type D enterotoxaemia. II. Structural and ultrastructural alterations in the tissues of lambs and mice. J Comp Pathol. 83:1973;509-524.
26. Morgan K.T., Kelly B.G. Ultrastructural study of brain lesions produced in mice by the administration of Clostridium welchii type D toxin. J Comp Pathol. 84:1974;181-191.
27. Finnie J.W. Histopathological changes in the brain of mice given Clostridium perfringens type D epsilon toxin. J Comp Pathol. 94:1984;363-370.
28. Finnie J.W. Ultrastructural changes in the brain of mice given Clostridium perfringens type D epsilon toxin. J Comp Pathol. 94:1984;445-452.
29. Morgan K.T., Kelly B.G., Buxton D. Vascular leakage produced in the brains of mice by Clostridium welchii type D toxin. J Comp Pathol. 85:1975;461-466.
30. Finnie J.W., Blumbergs P.C., Manavis J. Neuronal damage produced in rat brains by Clostridium perfringens type D epsilon toxin. J Comp Pathol. 120:1999;415-420.
31. Ghabriel M.N., Zhu C., Reilly P.L., Blumbergs P.C., Manavis J., Finnie J.W. Toxin-induced vasogenic cerebral oedema in a rat model. Acta Neurochir Suppl. 76:2000;231-236.
32. Nagahama M., Sakurai J. Distribution of labelled Clostridium perfringens epsilon toxin in mice. Toxicon. 29:1991;211-217.
33. Okabe A, Miyata S, Tamai E, Minami J, Shimamoto S, Matsushita O. The molecular mechanism of Clostridium perfringens epsilon-toxin cytotoxicity. Proceedings of the 4th International Conference on the Molecular Biology and Pathogenesis of the Clostridia, April 26-30, Woods Hole, MA, USA, 2003.
34. Buxton D. The use of an immunoperoxidase technique to investigate by light and electron microscopy the site of binding of Clostridium welchii type D epsilon toxin in mice. J Med Microbiol. 11:1978;289-292.
35. Buxton D., Morgan K.T. Studies of lesions in the brains of colostrum deprived lambs by Clostridium welchii (Cl. p) type D toxin. J Comp Pathol. 86:1976;435-447.
36. Uzal F.A., Rolfe B.E., Smith N.J., Thomas A.C., Kelly W.R. Resistance of ovine, caprine and bovine endothelial cells to Clostridium perfringens type D epsilon toxin. Vet Res Commun. 23:1999;275-284.
37. Ironside J.W., Pickard J.D. Raised intracranial pressure, oedema and hydrocephalus. Graham D.I., Lantos P.L. Greenfield's neuropathology. 7th ed:2002;193-225 Arnold, London.
38. Miyakawa MF, Ghoddusi M, Kelly WR, Uzal FA. Effect of Clostridium perfringens type D epsilon toxin on ovine carotid arteries in vitro. Proceedings of the 4th International Conference on the Molecular Biology and Pathogenesis of the Clostridia. April 26-30. Woods Hole, MA, USA, 2003.
39. Buxton D. Use of horseradish peroxidase to study the antagonism of Clostridium welchii (Cl. p) type D epsilon toxin in mice by the formalinised epsilon prototoxin. J Comp Pathol. 86:1976;67-72.
40. Nagahama M., Ochi S., Sakurai J. Assembly of Clostridium perfringens epsilon-toxin on MDCK cell membrane. J Nat Toxins. 7:1998;291-302.
41. Nagahama M., Sakurai J. High affinity binding of Clostridium perfringens epsilon toxin to rat brain. Infect Immun. 60:1992;1237-1240.
42. 131 radioiodinated serum albumin in brains of Clostridium perfringens type D intoxicated lambs. J Am Vet Med Assoc. 22:1961;443-446.
43. Worthington R.W., Mulders M.S.G. The effect of Clostridium perfringens epsilon toxin on the blood-brain barrier of mice. Onderstepoort J Vet Res. 42:1975;25-28.
44. Finnie J.W., Hajduk P. An immunohistochemical study of plasma albumin extravasation in the brain of mice after the administration of Clostridium perfringens type D epsilon toxin. Aust Vet J. 69:1992;261-262.
45. Zhu C., Ghabriel M.N., Blumbergs P.C., Reilly P.L., Finnie J.W. Clostridium perfringens prototoxin-induced alteration of endothelial barrier antigen (EBA) immunoreactivity at the blood-brain barrier (BBB). Exp Neurol. 169:2001;72-82.
46. Gardner D.E. Brain oedema. an experimental model J Exp Pathol. 55:1974;453-457.
47. Uzal F.A., Kelly W.R. Effects of the intravenous administration of Clostridium perfringens type D epsilon toxin on young goats and lambs. J Comp Pathol. 116:1997;63-71.
48. Uzal F.A., Kelly W.R. Experimental Clostridium perfringens type D enterotoxaemia in goats. Vet Pathol. 35:1998;132-140.
49. Uzal F.A., Kelly W.R., Morris W.E., Assis R.A. Effects of intravenous injection of Clostridium perfringens type D epsilon toxin in calves. J Comp Pathol. 126:2002;71-75.
50. Auer R.N., Sutherland G.R. Hypoxia and related conditions. Graham D.I., Lantos P.L. Greenfield's neuropathology. 7th ed:2002;233-264 Arnold, London.
51. Cole AR, Popoff MR, Moss DS, Titball RW, Basak AK. Crystal structure of epsilon toxin reveals the mode of action. Proceedings of the 4th International Conference on the Molecular Biology and Pathogenesis of the Clostridia. April 26-30. Woods Hole, MA, USA, 2003.
52. Miyamoto O., Minami J., Toyoshima T.et al. Neurotoxicity of Clostridium perfringens epsilon-toxin for the rat hippocampus via the glutamatergic system. Infect Immun. 66:1998;2501-2508.
53. Miyamoto O., Sumitani K., Nakamura T.et al. Clostridium perfringens epsilon toxin causes excessive release of glutamate in the mouse hippocampus. FEMS Microbiol Lett. 189:2000;109-113.
54. Nagahama M., Sakurai J. Effect of drugs acting on the central nervous system on the lethality in mice of Clostridium perfringens epsilon toxin. Toxicon. 31:1993;427-435.
55. Innes JRM, Saunders LZ. Comparative neuropathology. New York: Academic Press; 1962. p. 607-23.