Clostridium perfringens epsilon toxin causes selective death of mature oligodendrocytes and central nervous system demyelination

mBio

Volumn 6, Issue 3, 2015, Pages

  Linden, Jennifer R ^a   Ma, Yinghua ^a   Zhao, Baohua ^a   Harris, Jason Michael ^a   Rumah, Kareem Rashid ^a   Schaeren Wiemers, Nicole ^b   Vartanian, Timothy ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; CLOSTRIDIUM PERFRINGENS EPSILON TOXIN; MYELIN AND LYMPHOCYTE PROTEIN; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; CLOSTRIDIUM PERFRINGENS EPSILON-TOXIN; MAL PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING KINETICS; CELL CULTURE; CELL DEATH; CELL LINEAGE; CELL MATURATION; CELL SPECIFICITY; CLOSTRIDIUM PERFRINGENS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEMYELINATION; GLIA CELL; MICROGLIA; MOLECULAR MECHANICS; MOUSE; NERVE CELL; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; OLIGODENDROGLIA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIME; WHITE MATTER; ANIMAL; C57BL MOUSE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CHEMICALLY INDUCED; DEFICIENCY; DEMYELINATING DISEASE; DRUG EFFECTS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALIA; BACTERIA (MICROORGANISMS); CLOSTRIDIUM PERFRINGENS;

ANIMALS; BACTERIAL TOXINS; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN AND LYMPHOCYTE-ASSOCIATED PROTEOLIPID PROTEINS; OLIGODENDROGLIA;

EID: 84936971177     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.02513-14     Document Type: Article

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