The Legionella longbeachae Icm/Dot substrate SidC selectively binds phosphatidylinositol 4-phosphate with nanomolar affinity and promotes pathogen vacuole-endoplasmic reticulum interactions

Infection and Immunity

Volumn 82, Issue 10, 2014, Pages 4021-4033

  Dolinsky, Stephanie ^a   Haneburger, Ina ^a,b   Cichy, Adam ^c   Hannemann, Mandy ^c   Itzen, Aymelt ^c   Hilbi, Hubert ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c Munich Center for Integrated Protein Science   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALNEXIN; PHOSPHATIDYLINOSITOL 4 PHOSPHATE; BACTERIAL PROTEIN; PHOSPHATIDYLINOSITOL 4-PHOSPHATE; POLYPHOSPHOINOSITIDE;

ACANTHAMOEBA CASTELLANII; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; BINDING AFFINITY; CELL INTERACTION; CELL VACUOLE; CONTROLLED STUDY; DELETION MUTANT; DICTYOSTELIUM DISCOIDEUM; ENDOPLASMIC RETICULUM; ENZYME BINDING; HOST PATHOGEN INTERACTION; ISOTHERMAL TITRATION CALORIMETRY; LEGIONELLA LONGBEACHAE; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; MACROPHAGE; NONHUMAN; SDCA GENE; SIDC GENE; TYPE IV SECRETION SYSTEM; WILD TYPE; ANIMAL; CALORIMETRY; CELL LINE; CHEMISTRY; CHROMOSOME MAP; DICTYOSTELIUM; GENE DELETION; GENETICS; KINETICS; METABOLISM; MICROBIOLOGY; MOLECULAR WEIGHT; MOUSE; PHYSIOLOGY; PROTEIN BINDING;

ACANTHAMOEBA CASTELLANII; ANIMALS; BACTERIAL PROTEINS; CALNEXIN; CALORIMETRY; CELL LINE; CHROMOSOME MAPPING; DICTYOSTELIUM; ENDOPLASMIC RETICULUM; GENE DELETION; HOST-PATHOGEN INTERACTIONS; KINETICS; LEGIONELLA LONGBEACHAE; MACROPHAGES; MICE; MOLECULAR WEIGHT; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN BINDING; VACUOLES;

EID: 84907099490     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01685-14     Document Type: Article

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